公开(公告)号：US09376547B2

公开(公告)日：2016-06-28

申请号：US14775184

申请日：2014-03-12

申请人： KANEKA CORPORATION

发明人： Koji Noda ,  Ryohei Ishimaru ,  Satohiro Yanagisawa ,  Masashi Izumida

IPC分类号： C08K5/35 ,  C08F2/26 ,  C07K1/14 ,  C07K1/36

CPC分类号： C08K5/35 ,  C08F2/26 ,  C08F220/14 ,  C08F220/18 ,  C08F2220/1825 ,  C08F220/40

摘要： The objective of the present invention is to provide a method for producing a polymer of a monomer having a vinyl group while reducing a residual amount of a surfactant within the polymer as the target compound and waste water. The method for producing a polymer according to the present invention is characterized in comprising the step of polymerizing a monomer having a vinyl group in an aqueous medium in the presence of a surfactin salt, which is a natural peptide surfactant, and a polymerization initiator, wherein a ratio of the surfactin salt (I) to 100 parts by mass of the monomer is not less than 0.0005 parts by mass and less than 0.1 parts by mass.

摘要翻译： 本发明的目的是提供一种制备具有乙烯基的单体的聚合物的方法，同时减少作为目标化合物和废水的聚合物内的表面活性剂的残留量。 本发明的聚合物的制造方法的特征在于，在作为天然肽表面活性剂的表面活性素盐的存在下，在水性介质中聚合具有乙烯基的单体和聚合引发剂的工序，其中， 表面活性素盐（I）与100质量份单体的比例为0.0005质量份以上且小于0.1质量份。

公开(公告)号：US08993800B2

公开(公告)日：2015-03-31

申请号：US13897079

申请日：2013-05-17

申请人： Kaneka Corporation

发明人： Takahiro Ohishi ,  Hirokazu Nanba ,  Masanobu Sugawara ,  Masashi Izumida ,  Tatsuya Honda ,  Kohei Mori ,  Satohiro Yanagisawa ,  Nobuo Nagashima ,  Kenji Inoue

IPC分类号： C07C315/00 ,  C12P13/12 ,  C07C319/06 ,  C07D233/76 ,  C12P17/04 ,  C12P17/10 ,  C12P41/00

CPC分类号： C12P13/12 ,  C07C319/06 ,  C07D233/76 ,  C12P17/04 ,  C12P17/10 ,  C12P41/009 ,  C07C323/58

摘要： The present invention provides a simple industrial process for producing an L- or D-optically active α-methylcysteine derivative or its salt, which is a useful pharmaceutical intermediate, from readily available, inexpensive raw materials. In a process for producing an L- or D-optically active α-methylcysteine derivative or its salt, a racemic N-carbamoyl-α-methylcysteine derivative or its salt is D-selectively cyclized with hydantoinase to produce a D-5-methyl-5-thiomethylhydantoin derivative or its salt and an N-carbamoyl-α-methyl-L-cysteine derivative or its salt, which are then subjected to deprotection of the amino group and the sulfur atom, and hydrolysis.

摘要翻译： 本发明提供了一种简单的工业方法，用于从容易获得的便宜的原料制备作为有用的药物中间体的L-或D-光学活性的α-甲基半胱氨酸衍生物或其盐。 在制备L-或D-光学活性α-甲基半胱氨酸衍生物或其盐的方法中，外消旋的N-氨基甲酰基-α-甲基半胱氨酸衍生物或其盐与乙内酰脲酶D选择性环化以产生D-5-甲基 - 5-硫代甲基乙内酰脲衍生物或其盐和N-氨基甲酰基-α-甲基-L-半胱氨酸衍生物或其盐，然后进行氨基和硫原子的脱保护和水解。

公开(公告)号：US10035974B2

公开(公告)日：2018-07-31

申请号：US14778685

申请日：2014-03-25

申请人： KANEKA CORPORATION ,  NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY

发明人： Koji Noda ,  Masashi Izumida ,  Satohiro Yanagisawa ,  Tohru Nakashima ,  Takuto Nagano ,  Toshiaki Taira ,  Tomohiro Imura ,  Dai Kitamoto

IPC分类号： C11D1/10 ,  B05D3/00 ,  C07K7/56 ,  B08B3/10

CPC分类号： C11D1/10 ,  B05D3/002 ,  B08B3/10 ,  C07K7/56

摘要： The objective of the present invention is to provide a cleaning agent composition which can be used in the open air without any problems since the cleaning agent is environmentally friendly and which is effective for removing a low-molecular-weight and poorly-water-soluble cyclic silicone compound that causes a stain of a silicone sealing. The cleaning agent for washing out a silicone stain according to the present invention is characterized in comprising a cyclic lipopeptide biosurfactant, wherein the specific silicone stain compound such as D4 compound is the objective compound to be removed.

公开(公告)号：US09868097B2

公开(公告)日：2018-01-16

申请号：US15121630

申请日：2015-03-03

申请人： KANEKA CORPORATION ,  NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY

发明人： Satohiro Yanagisawa ,  Takuto Nagano ,  Masashi Izumida ,  Toshiaki Taira ,  Tomohiro Imura ,  Dai Kitamoto

IPC分类号： A61K38/08 ,  A61K47/00 ,  B01F17/00 ,  A61K8/64 ,  A61K47/20 ,  C11D1/10 ,  A61K47/18 ,  A61Q19/00 ,  A23L33/10 ,  A23L2/52 ,  A61K8/46 ,  A61K47/42 ,  C05G3/00 ,  C09D7/12 ,  C11D1/00 ,  C11D1/22 ,  D21H17/09 ,  D21H17/20 ,  D21H27/20 ,  A61K8/36 ,  A61K8/70 ,  A61Q5/02 ,  A61Q11/00 ,  A61Q15/00 ,  A61Q17/04

CPC分类号： B01F17/005 ,  A23L2/52 ,  A23L33/10 ,  A23V2002/00 ,  A61K8/361 ,  A61K8/463 ,  A61K8/466 ,  A61K8/64 ,  A61K8/70 ,  A61K47/183 ,  A61K47/20 ,  A61K47/42 ,  A61K2800/10 ,  A61K2800/596 ,  A61Q5/02 ,  A61Q11/00 ,  A61Q15/00 ,  A61Q17/04 ,  A61Q19/00 ,  A61Q19/007 ,  B01F17/0057 ,  B01F17/0085 ,  C05G3/00 ,  C09D7/41 ,  C09D7/63 ,  C09D7/65 ,  C11D1/008 ,  C11D1/10 ,  C11D1/22 ,  D21H17/09 ,  D21H17/20 ,  D21H27/20

摘要： The objective of the present invention is to provide a method for remarkably reducing a critical micelle concentration of an anionic surfactant, which is used in a large amount currently, to reduce the amount to be used. Also, the objective of the present invention is to provide a surfactant composition of which whole critical micelle concentration is remarkably reduced and in which an amount of an anionic surfactant is reduced in comparison with the case of using an anionic surfactant only as a surfactant. The method for reducing a critical micelle concentration of an anionic surfactant according to the present invention is characterized in using a cyclic lipopeptide biosurfactant in combination with the anionic surfactant.

公开(公告)号：US20130261331A1

公开(公告)日：2013-10-03

申请号：US13897079

申请日：2013-05-17

申请人： Kaneka Corporation

发明人： Takahiro Ohishi ,  Hirokazu Nanba ,  Masanobu Sugawara ,  Masashi Izumida ,  Tatsuya Honda ,  Kohei Mori ,  Satohiro Yanagisawa ,  Nabuo Nagashima ,  Kenji Inoue

IPC分类号： C12P13/12

CPC分类号： C12P13/12 ,  C07C319/06 ,  C07D233/76 ,  C12P17/04 ,  C12P17/10 ,  C12P41/009 ,  C07C323/58

摘要： The present invention provides a simple industrial process for producing an L- or D-optically active α-methylcysteine derivative or its salt, which is a useful pharmaceutical intermediate, from readily available, inexpensive raw materials. In a process for producing an L- or D-optically active α-methylcysteine derivative or its salt, a racemic N-carbamoyl-α-methylcysteine derivative or its salt is D-selectively cyclized with hydantoinase to produce a D-5-methyl-5-thiomethylhydantoin derivative or its salt and an N-carbamoyl-α-methyl-L-cysteine derivative or its salt, which are then subjected to deprotection of the amino group and the sulfur atom, and hydrolysis.

摘要翻译： 本发明提供了一种用于从容易得到的廉价原料生产L-或D-光学活性α-甲基半胱氨酸衍生物或其盐的简单工业方法，其是有用的药物中间体。 在制备L-或D-光学活性α-甲基半胱氨酸衍生物或其盐的方法中，外消旋的N-氨基甲酰基-α-甲基半胱氨酸衍生物或其盐与乙内酰脲酶D选择性环化以产生D-5-甲基 - 5-硫代甲基乙内酰脲衍生物或其盐和N-氨基甲酰基-α-甲基-L-半胱氨酸衍生物或其盐，然后对氨基和硫原子进行脱保护和水解。