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    Excimer laser beam irradiation apparatus for optically processing workpiece
    1.
    发明授权
    Excimer laser beam irradiation apparatus for optically processing workpiece 失效
    用于光学处理工件的准分子激光束照射装置

    公开(公告)号：US5661744A

    公开(公告)日：1997-08-26

    申请号：US512710

    申请日：1995-08-08

    申请人： Kazuyuki Murakami ,  Hajime Nakatani ,  Atsushi Sugitatsu ,  Tadao Minagawa ,  Toshinori Yagi ,  Keiko Ito

    发明人： Kazuyuki Murakami ,  Hajime Nakatani ,  Atsushi Sugitatsu ,  Tadao Minagawa ,  Toshinori Yagi ,  Keiko Ito

    IPC分类号： B23K26/38 ,  H05K3/00 ,  H05K3/46 ,  H01S3/22 ,  H01S3/223

    CPC分类号： B23K26/083 ,  B23K26/066

    摘要： An excimer laser beam irradiation apparatus capable of processing a workpiece optimally with an excimer irradiation beam even when intensity distribution of the excimer laser beam undergone multiple reflections is non-uniform. A patterning mask has light-transmissive portions for allowing the excimer laser beam to pass through and a reflecting layer for reflecting it. A high reflectivity mirror disposed in opposition to the reflecting layer reflects the excimer laser beam reflected from the reflecting layer toward the patterning mask. An imaging lens images a pattern of the excimer laser beam transmitted through the patterning mask onto a workpiece for irradiation thereof. A workpiece moving mechanism and a mask moving mechanism move the workpiece and the mask moving mechanism, respectively. A control unit controls the workpiece moving mechanism and the mask moving mechanism such that the patterning mask and the workpiece are displaced along a same axis synchronously with each other in a scan moving direction which coincides with a direction in which the excimer laser beam shifts positionally while being reflected between the patterning mask and the reflecting means, for thereby allowing the workpiece to be scanned with the excimer laser beam. The workpiece can be processed uniformly and stably in accordance with a pattern of the patterning mask with high accuracy and reliability.

    摘要翻译： 即使准分子激光束的强度分布发生多次反射也能够用准分子照射光束最佳地处理工件的准分子激光束照射装置是不均匀的。 图形掩模具有用于允许准分子激光束通过的透光部分和用于反射它的反射层。 与反射层相对设置的高反射率反射镜将从反射层反射的准分子激光束朝向图案掩模反射。 成像透镜将通过图案化掩模透射的准分子激光束的图案成像到工件上以进行照射。 工件移动机构和掩模移动机构分别移动工件和掩模移动机构。 控制单元控制工件移动机构和掩模移动机构，使得图案掩模和工件沿着与准分子激光束在位置上移动的方向一致的扫描移动方向沿同一轴线同步地移位，同时 在图案掩模和反射装置之间被反射，从而允许用准分子激光束扫描工件。 可以以高精度和可靠性根据图案化掩模的图案均匀且稳定地加工工件。

    Assay kit for use in method of detecting a target nucleic acid
    2.
    发明授权
    Assay kit for use in method of detecting a target nucleic acid 有权
    用于检测靶核酸的方法的测定试剂盒

    公开(公告)号：US07951541B2

    公开(公告)日：2011-05-31

    申请号：US12851675

    申请日：2010-08-06

    申请人： Naoko Nakamura ,  Keiko Ito

    发明人： Naoko Nakamura ,  Keiko Ito

    IPC分类号： C12Q1/68 ,  C12P19/34

    CPC分类号： C12Q1/6844 ,  C12Q2525/161 ,  C12Q2525/301 ,  C12Q2531/101

    摘要： Kits for use in a method of detecting an amplification product by hybridizing it with a probe, the amplification product is amplified from a target nucleic acid with the primers, including placing F3, F2 and F1 regions in this order from a 5′ terminal side and B3c, B2c and B1c regions in this order from a 3′ terminal side, and additionally an FP region in the region from the F2 to F1 regions and/or a BPc region in the region from the B2c to B1c regions in the target nucleic acid, determining the respective regions in such a manner that the FP and F2 regions and/or the BPc and B2c regions have an unoverlapping region of at least 10 bases or more and overlapping regions of 10 bases or less, and designing the primers according to the regions.

    摘要翻译： 用于通过与探针杂交来检测扩增产物的方法的试剂盒，使用引物从靶核酸扩增扩增产物，包括从5'末端侧依次放置F3，F2和F1区， B3c，B2c和B1c区域，另外在靶核酸中的从B2c到B1c区域的F2到F1区和/或BPc区的区域中的FP区域 以这样的方式确定各个区域，使得FP和F2区域和/或BPc和B2c区域具有至少10个碱基以上的重叠区域和10个碱基以下的重叠区域，并且根据 地区。

    SEPARATION CONTAINER, ATTACHMENT AND SEPARATION METHOD
    3.
    发明申请
    SEPARATION CONTAINER, ATTACHMENT AND SEPARATION METHOD 审中-公开
    分离容器，附件和分离方法

    公开(公告)号：US20100222196A1

    公开(公告)日：2010-09-02

    申请号：US12739096

    申请日：2008-10-23

    申请人： Keiko Ito ,  Satoshi Hirai ,  Osamu Okitsu ,  Yasunori Okamoto

    发明人： Keiko Ito ,  Satoshi Hirai ,  Osamu Okitsu ,  Yasunori Okamoto

    IPC分类号： B01D21/26 ,  B04B11/00

    CPC分类号： B01L3/5021 ,  B01L2200/026 ,  B01L2300/041 ,  B01L2300/047 ,  B01L2300/0618 ,  B01L2300/0681 ,  G01N2035/00495

    摘要： A separation container that can prevent the contamination with unnecessary components is provided. A separation container 1 for separating a separation subject from a sample by causing the separation subject to gather on the bottom thereof by centrifugation includes a container main body 11 and a dividing portion. The container main body 11 is a tubular container elongated in the axial direction with an upper end thereof being open and a lower end thereof being the bottom. The dividing portion has a partition 12 formed along the axial direction of the container main body, and an inner space of the container main body 11 is divided into a sample supply chamber 14 and a separation subject discharge chamber 15 by the partition 12. The sample supply chamber 14 and the separation subject discharge chamber 15 communicate with each other via a through hole 13 formed in a lower portion of the partition 12. A collection tube can be inserted into a lower portion of the separation subject discharge chamber 15 from the opening, and the separation subject located in the lower portion of the separation subject discharge chamber 15 can be collected with the collection tube and recovered to the outside of the container main body 11.

    摘要翻译： 提供了可以防止不必要的部件污染的分离容器。 用于通过使分离对象通过离心而聚集在其底部的分离对象与样品分离的分离容器1包括容器主体11和分隔部。 容器主体11是沿轴向延伸的管状容器，其上端开口，下端为底部。 分隔部具有沿着容器主体的轴向形成的隔壁12，容器主体11的内部空间被分隔件12分割成样品供给室14和分离对象排出室15.样品 供给室14和分离对象物排出室15通过形成在分隔部12的下部的通孔13相互连通。收集管可以从开口插入分离对象排出室15的下部， 并且分离对象物排出室15的下部的分离对象能够与收集管一起收集并回收到容器主体11的外部。

    METHOD OF DESIGNING PRIMERS FOR USE IN METHOD OF DETECTING TARGET NUCLEIC ACID AND ASSAY KIT
    4.
    发明申请
    METHOD OF DESIGNING PRIMERS FOR USE IN METHOD OF DETECTING TARGET NUCLEIC ACID AND ASSAY KIT 有权
    设计用于检测目标核酸和测定试剂盒的方法中使用的方法

    公开(公告)号：US20090117544A1

    公开(公告)日：2009-05-07

    申请号：US11624814

    申请日：2007-01-19

    申请人： Naoko Nakamura ,  Keiko Ito

    发明人： Naoko Nakamura ,  Keiko Ito

    IPC分类号： C12Q1/68 ,  C07H21/04

    CPC分类号： C12Q1/6844 ,  C12Q2525/161 ,  C12Q2525/301 ,  C12Q2531/101

    摘要： A method of designing primers for use in a method of detecting an amplification product by hybridizing it with a probe, the amplification product is amplified from a target nucleic acid with the primers, including placing F3, F2 and F1 regions in this order from a 5′ terminal side and Bc, B2c and B1c regions in this order from a 3′ terminal side, and additionally an FP region in the region from the F2 to F1 regions and/or a BPc region in the region from the B2c to B1c regions in the target nucleic acid, determining the respective regions in such a manner that the FP and F2 regions and/or the BPc and B2c regions have an unoverlapping region of at least 10 bases or more and overlapping regions of 10 bases or less, and designing the primers according to the regions.

    摘要翻译： 一种设计引物用于通过与探针杂交来检测扩增产物的方法的引物的方法，用引物从靶核酸扩增扩增产物，其中包括将F3，F2和F1区域从5 '端子侧和Bc，B2c和B1c区域，另外在从F2到F1区域的区域中的FP区域和/或从B2c到B1c区域的区域中的BPc区域 靶核酸，以使得FP和F2区域和/或BPc和B2c区域具有至少10个碱基以上的不重叠区域和10个碱基以下的重叠区域的方式来确定各个区域，并且设计 引物根据区域。

    Semiconductor device having a fuse layer
    5.
    发明授权
    Semiconductor device having a fuse layer 失效
    具有熔丝层的半导体器件

    公开(公告)号：US5872389A

    公开(公告)日：1999-02-16

    申请号：US672867

    申请日：1996-06-28

    申请人： Yasumasa Nishimura ,  Keiko Ito ,  Hiroyuki Takeoka ,  Masanao Maruta ,  Masaharu Moriyasu

    发明人： Yasumasa Nishimura ,  Keiko Ito ,  Hiroyuki Takeoka ,  Masanao Maruta ,  Masaharu Moriyasu

    IPC分类号： H01L21/82 ,  H01L23/525 ,  H01L27/10 ,  H01L29/00

    CPC分类号： H01L23/5258 ,  H01L2924/0002

    摘要： Burst pressure P of an insulating layer positioned immediately on a fuse layer is defined by using planar width W of fuse layer and thickness t of insulating layer. The value of the planar width W of fuse layer and the value of the thickness t of insulating layer are set such that the value of burst pressure P is at most about 1000 kg/cm.sup.2. The value of the thickness t and the value of the planar width W are set such that the value t/W is at least 0.45 and at most 0.91. Consequently, stable fuse blowing becomes possible while reducing manufacturing cost.

    摘要翻译： 通过使用熔丝层的平面宽度W和绝缘层的厚度t来定义紧靠在熔丝层上的绝缘层的爆破压力P. 熔丝层的平面宽度W的值和绝缘层的厚度t的值被设定为使得爆破压力P的值为至多约1000kg / cm 2。 厚度t的值和平面宽度W的值被设定为使得值t / W为至少0.45且至多为0.91。 因此，可以在降低制造成本的同时实现稳定的熔断器熔断。

    METHOD OF DESIGNING PRIMERS FOR USE IN METHOD OF DETECTING TARGET NUCLEIC ACID AND ASSAY KIT
    6.
    发明申请
    METHOD OF DESIGNING PRIMERS FOR USE IN METHOD OF DETECTING TARGET NUCLEIC ACID AND ASSAY KIT 有权
    设计用于检测目标核酸和测定试剂盒的方法中使用的方法

    公开(公告)号：US20110021379A1

    公开(公告)日：2011-01-27

    申请号：US12851675

    申请日：2010-08-06

    申请人： Naoko NAKAMURA ,  Keiko Ito

    发明人： Naoko NAKAMURA ,  Keiko Ito

    IPC分类号： C40B40/06 ,  C12Q1/68

    CPC分类号： C12Q1/6844 ,  C12Q2525/161 ,  C12Q2525/301 ,  C12Q2531/101

    摘要： Kits for use in a method of detecting an amplification product by hybridizing it with a probe, the amplification product is amplified from a target nucleic acid with the primers, including placing F3, F2 and F1 regions in this order from a 5′ terminal side and B3c, B2c and B1c regions in this order from a 3′ terminal side, and additionally an FP region in the region from the F2 to F1 regions and/or a BPc region in the region from the B2c to B1c regions in the target nucleic acid, determining the respective regions in such a manner that the FP and F2 regions and/or the BPc and B2c regions have an unoverlapping region of at least 10 bases or more and overlapping regions of 10 bases or less, and designing the primers according to the regions.

    摘要翻译： 用于通过与探针杂交来检测扩增产物的方法的试剂盒，使用引物从靶核酸扩增扩增产物，包括从5'末端侧依次放置F3，F2和F1区， B3c，B2c和B1c区域，另外在靶核酸中的从B2c到B1c区域的F2到F1区和/或BPc区的区域中的FP区域 以这样的方式确定各个区域，使得FP和F2区域和/或BPc和B2c区域具有至少10个碱基以上的重叠区域和10个碱基以下的重叠区域，并且根据 地区。

    Gene detection method
    10.
    发明授权
    Gene detection method 失效
    基因检测方法

    公开(公告)号：US5972692A

    公开(公告)日：1999-10-26

    申请号：US886161

    申请日：1997-06-30

    申请人： Koji Hashimoto ,  Keiko Ito ,  Yoshio Ishimori

    发明人： Koji Hashimoto ,  Keiko Ito ,  Yoshio Ishimori

    IPC分类号： C12N15/10 ,  C12Q1/68 ,  C12M3/04 ,  C12M1/00

    CPC分类号： C12Q1/6834 ,  B01L7/525 ,  C12N15/1006 ,  C12Q1/6816 ,  C12Q1/6825 ,  G01N27/3276 ,  B01L2300/0645 ,  B01L2300/0819 ,  B01L3/50851 ,  B01L7/54

    摘要： A single stranded nucleic acid probe having a base sequence complementary to the gene to be detected is immobilized onto the surface of an electrode or the tip of an optical fiber, and the nucleic probe is reacted with the gene sample denatured to a single stranded form, and then the nucleic acid probe hybridized with the gene is detected. In this procedure, to the reaction system consisting of the nucleic acid probe and the gene sample, a double stranded nucleic acid recognizing substance capable of binding specifically to the double stranded nucleic acid and being active electrochemically or optically is added. The detection of the nucleic acid probe is conducted by electrochemical or optical determination utilizing the electrode or optical fiber mentioned above. By this method, safer and more convenient detection of the gene is possible at a higher sensitivity even in a reduced time period.

    摘要翻译： 将具有与待检测基因互补的碱基序列的单链核酸探针固定在电极表面或光纤尖端上，使核酸探针与基因样品变性为单链形式， 然后检测与该基因杂交的核酸探针。 在该方法中，对于由核酸探针和基因样品构成的反应体系，添加能够特异性结合双链核酸并且以电化学或光学活性结合的双链核酸识别物质。 通过使用上述电极或光纤的电化学或光学测定来进行核酸探针的检测。 通过这种方法，即使在减少的时间内也可以以更高的灵敏度检测更基础的基因。