公开(公告)号：US20100074296A1

公开(公告)日：2010-03-25

申请号：US12513176

申请日：2007-12-06

申请人： Kuniaki Iwashiro ,  Hiroyuki Suzuki ,  Tetsuo Kojima ,  Tomotaka Katsura

发明人： Kuniaki Iwashiro ,  Hiroyuki Suzuki ,  Tetsuo Kojima ,  Tomotaka Katsura

IPC分类号： H01S3/08

CPC分类号： H01S3/08045 ,  G02F1/353 ,  G02F1/37 ,  G02F2001/3503 ,  G02F2001/3507 ,  G02F2001/354 ,  H01S3/08 ,  H01S3/08072

摘要： Two convex lenses (61, 62), each of which has a focal length “f”, and a 90 degree polarization rotator (5) are interposed between solid-state laser elements (21, 22) of a symmetrical resonator having the two solid-state laser elements (21, 22); a space between the two lenses (61, 62) is made shorter than 2f; and distances between the respective lenses (61, 62) and centers of their adjacent solid-state laser elements (21, 22) are set substantially to “f”, to thus achieve a solid-state laser capable of stably performing high power transverse single mode oscillation desirably having power of 100 W or more. There is acquired a wavelength conversion laser that is further provided with a Q switch (3) and a polarization element (4) and that causes an output fundamental wave laser beam to enter nonlinear elements (91, 92) so as to undergo wavelength conversion, thereby producing a high power harmonic laser beam having a high frequency of; desirably, about 100 kHz.

摘要翻译： 在具有两个固体的对称共振器的固体激光元件（21,22）之间插入两个具有焦距“f”的凸透镜（61,62）和90度偏振旋转器（5） 状态激光元件（21,22）; 使两个透镜（61,62）之间的空间短于2f; 并且各透镜（61,62）与其相邻的固体激光元件（21,22）的中心之间的距离设定为大致为“f”，从而实现能够稳定地执行大功率横向单 期望具有100W或更大的功率的模式振荡。 获得进一步设置有Q开关（3）和偏振元件（4）的波长转换激光器，并且使得输出基波激光束进入非线性元件（91,92）以进行波长转换， 从而产生具有高频率的高功率谐波激光束; 理想地，约100kHz。

公开(公告)号：US07936804B2

公开(公告)日：2011-05-03

申请号：US12513176

申请日：2007-12-06

申请人： Kuniaki Iwashiro ,  Hiroyuki Suzuki ,  Tetsuo Kojima ,  Tomotaka Katsura

发明人： Kuniaki Iwashiro ,  Hiroyuki Suzuki ,  Tetsuo Kojima ,  Tomotaka Katsura

IPC分类号： H01S3/08

CPC分类号： H01S3/08045 ,  G02F1/353 ,  G02F1/37 ,  G02F2001/3503 ,  G02F2001/3507 ,  G02F2001/354 ,  H01S3/08 ,  H01S3/08072

摘要： Two convex lenses (61, 62), each of which has a focal length “f”, and a 90 degree polarization rotator (5) are interposed between solid-state laser elements (21, 22) of a symmetrical resonator having the two solid-state laser elements (21, 22); a space between the two lenses (61, 62) is made shorter than 2f; and distances between the respective lenses (61, 62) and centers of their adjacent solid-state laser elements (21, 22) are set substantially to “f”, to thus achieve a solid-state laser capable of stably performing high power transverse single mode oscillation desirably having power of 100 W or more. There is acquired a wavelength conversion laser that is further provided with a Q switch (3) and a polarization element (4) and that causes an output fundamental wave laser beam to enter nonlinear elements (91, 92) so as to undergo wavelength conversion, thereby producing a high power harmonic laser beam having a high frequency of; desirably, about 100 kHz.

摘要翻译： 在具有两个固体的对称共振器的固体激光元件（21,22）之间插入两个具有焦距“f”的凸透镜（61,62）和90度偏振旋转器（5） 状态激光元件（21,22）; 使两个透镜（61,62）之间的空间短于2f; 并且各透镜（61,62）与其相邻的固体激光元件（21,22）的中心之间的距离设定为大致为“f”，从而实现能够稳定地执行大功率横向单 期望具有100W或更大的功率的模式振荡。 获得进一步设置有Q开关（3）和偏振元件（4）的波长转换激光器，并且使得输出基波激光束进入非线性元件（91,92）以进行波长转换， 从而产生具有高频率的高功率谐波激光束; 理想地，约100kHz。

公开(公告)号：US5359616A

公开(公告)日：1994-10-25

申请号：US114086

申请日：1993-08-31

申请人： Koji Yasui ,  Tetsuo Kojima ,  Takashi Yamamoto ,  Akira Ishimori ,  Kuniaki Iwashiro

发明人： Koji Yasui ,  Tetsuo Kojima ,  Takashi Yamamoto ,  Akira Ishimori ,  Kuniaki Iwashiro

IPC分类号： H01S3/06 ,  B23K26/06 ,  H01S3/04 ,  H01S3/042 ,  H01S3/07 ,  H01S3/08 ,  H01S3/093 ,  H01S3/0941 ,  H01S3/105 ,  H01S3/23 ,  H01S3/14

CPC分类号： H01S3/0931 ,  B23K26/0622 ,  H01S2301/20 ,  H01S2301/206 ,  H01S3/0407 ,  H01S3/042 ,  H01S3/061 ,  H01S3/0617 ,  H01S3/07 ,  H01S3/08 ,  H01S3/08063 ,  H01S3/08068 ,  H01S3/08072 ,  H01S3/08081 ,  H01S3/0941 ,  H01S3/23 ,  H01S3/2308

摘要： A solid state laser apparatus is provided to generate a high quality and high power laser beam, and a laser machining apparatus is provided to perform laser machining by a laser beam generated from the solid state laser apparatus. In the solid state laser apparatus, a laser resonator includes a solid state component cooled in a cylindrical pipe by contacting liquid which is introduced through an inflow opening and discharged through an outflow opening, the solid state component having larger refractive index than that of the liquid, a light source turned ON by a power source to excite the solid state component, and an optical system transmitting light from the light source to the solid state component. Further, a surface roughness of the solid state component is adjusted so as to adjust an excitation distribution in a section of the solid state component. The solid state component further includes moving means for moving a reflection mirror and a condensing lens in a direction of an optical axis of the laser resonator, and a housing accommodating an image transferring optical system. A laser beam is generated from the laser resonator, and is externally derived and used to perform the laser machining.

摘要翻译： 提供固体激光装置以产生高质量和高功率的激光束，并且提供激光加工装置以通过由固态激光装置产生的激光束进行激光加工。 在固体激光装置中，激光谐振器包括通过使通过流入开口引入并通过流出开口排出的液体接触在圆筒形管中冷却的固态成分，固体成分的折射率比液体的折射率大 通过电源将光源接通以激发固体成分，以及将光从光源透射到固体成分的光学系统。 此外，调整固体成分的表面粗糙度，以调整固体成分的截面中的激发分布。 固态分量还包括用于在激光谐振器的光轴的方向上移动反射镜和聚光透镜的移动装置，以及容纳图像转印光学系统的壳体。 从激光谐振器产生激光束，并从外部衍生并用于执行激光加工。

公开(公告)号：US07170911B2

公开(公告)日：2007-01-30

申请号：US10940817

申请日：2004-09-15

申请人： Tomotaka Katsura ,  Susumu Konno ,  Tetsuo Kojima ,  Junichi Nishimae

发明人： Tomotaka Katsura ,  Susumu Konno ,  Tetsuo Kojima ,  Junichi Nishimae

IPC分类号： H01S3/109

CPC分类号： H01S3/109 ,  G02F2001/3503 ,  G02F2001/3505 ,  G02F2001/354 ,  H01S3/005 ,  H01S3/1611 ,  H01S3/1643

摘要： A wavelength conversion apparatus in which output direction of a wavelength-converted laser beam, having a wavelength converted by a nonlinear optical crystal and emitted through an output-window, can be brought close to the direction of optical axis of the laser beam passing through the nonlinear optical crystal. In addition, axial deviation of the wavelength-converted laser beam converted by the nonlinear optical crystal and emitted through an output-window, can be reduced when the position of the nonlinear optical crystal is moved. The output facet of the nonlinear optical crystal is inclined at Brewster's angle with respect to the wavelength-converted laser beam. An output-window of a case containing the nonlinear optical crystal has a prism form in which the distance between a laser beam input facet and a laser beam output facet of the output-window is reduced along a direction in which the wavelength-converted laser beam, emitted from the nonlinear optical crystal, inclines.

摘要翻译： 一种波长转换装置，其中具有由非线性光学晶体转换并通过输出窗口发射的波长的波长转换激光束的输出方向可以靠近通过该激光束的激光束的光轴方向 非线性光学晶体。 此外，当非线性光学晶体的位置移动时，可以减少由非线性光学晶体转换并通过输出窗口发射的波长转换的激光束的轴向偏移。 非线性光学晶体的输出面相对于波长转换的激光束以布鲁斯特角倾斜。 包含非线性光学晶体的壳体的输出窗口具有棱镜形式，其中激光束输入面与输出窗口的激光束输出面之间的距离沿着波长转换激光束 ，从非线性光学晶体发射，倾斜。

公开(公告)号：US20090080475A1

公开(公告)日：2009-03-26

申请号：US12233174

申请日：2008-09-18

申请人： Masashi YOSHIMURA ,  Takatomo Sasaki ,  Yusuke Mori ,  Muneyuki Nishioka ,  Tomotaka Katsura ,  Tetsuo Kojima ,  Junichi Nishimae

发明人： Masashi YOSHIMURA ,  Takatomo Sasaki ,  Yusuke Mori ,  Muneyuki Nishioka ,  Tomotaka Katsura ,  Tetsuo Kojima ,  Junichi Nishimae

IPC分类号： H01S3/10 ,  G02F1/35 ,  C01B35/10

CPC分类号： G02F1/37 ,  G02F1/3551 ,  G02F2001/3505 ,  G02F2001/354

摘要： An optical wavelength conversion element includes a cesium-lithium-borate crystal processed into a 10-mm long optical element cut in an orientation that allows a fourth harmonic of a Nd:YAG laser to be generated. A transmittance (Ta) at 3589 cm−1 in an infrared transmission spectrum of the optical element is used as an index that indicates a content of water impurities in the crystal and is independent of a polarization direction. An actual measurement of the transmittance Ta is at least 1%, without taking into account loss at an optically polished surface of the crystal. A wavelength conversion device, a ultraviolet laser irradiation apparatus, a laser processing system, and a method of manufacturing an optical wavelength conversion element are also described.

摘要翻译： 光波长转换元件包括加工成允许产生Nd：YAG激光器的四次谐波的取向切割的10mm长的光学元件的铯 - 硼酸锂晶体。 光学元件的红外透射光谱中的3589cm -1处的透射率（Ta）被用作指示晶体中的水杂质含量并且与偏振方向无关的指标。 透射率Ta的实际测量值至少为1％，而不考虑在晶体的光学抛光表面处的损耗。 还描述了波长转换装置，紫外激光照射装置，激光加工系统和制造光波长转换元件的方法。

公开(公告)号：US20050068998A1

公开(公告)日：2005-03-31

申请号：US10940817

申请日：2004-09-15

申请人： Tomotaka Katsura ,  Susumu Konno ,  Tetsuo Kojima ,  Junichi Nishimae

发明人： Tomotaka Katsura ,  Susumu Konno ,  Tetsuo Kojima ,  Junichi Nishimae

IPC分类号： G02F1/37 ,  G02F1/015 ,  G02F2/02 ,  H01L21/02 ,  H01S3/00 ,  H01S3/10 ,  H01S3/109 ,  H01S3/16

CPC分类号： H01S3/109 ,  G02F2001/3503 ,  G02F2001/3505 ,  G02F2001/354 ,  H01S3/005 ,  H01S3/1611 ,  H01S3/1643

摘要： A wavelength conversion apparatus in which output direction of a wavelength-converted laser beam, having a wavelength converted by a nonlinear optical crystal and emitted through an output-window, can be brought close to the direction of optical axis of the laser beam passing through the nonlinear optical crystal. In addition, axial deviation of the wavelength-converted laser beam converted by the nonlinear optical crystal and emitted through an output-window, can be reduced when the position of the nonlinear optical crystal is moved. The output facet of the nonlinear optical crystal is inclined at Brewster's angle with respect to the wavelength-converted laser beam. An output-window of a case containing the nonlinear optical crystal has a prism form in which the distance between a laser beam input facet and a laser beam output facet of the output-window is reduced along a direction in which the wavelength-converted laser beam, emitted from the nonlinear optical crystal, inclines.

摘要翻译： 一种波长转换装置，其中具有由非线性光学晶体转换并通过输出窗口发射的波长的波长转换激光束的输出方向可以靠近通过该激光束的激光束的光轴方向 非线性光学晶体。 此外，当非线性光学晶体的位置移动时，可以减少由非线性光学晶体转换并通过输出窗口发射的波长转换的激光束的轴向偏移。 非线性光学晶体的输出面相对于波长转换的激光束以布鲁斯特角倾斜。 包含非线性光学晶体的壳体的输出窗口具有棱镜形式，其中激光束输入面与输出窗口的激光束输出面之间的距离沿着波长转换激光束 ，从非线性光学晶体发射，倾斜。

公开(公告)号：US07948673B2

公开(公告)日：2011-05-24

申请号：US12233174

申请日：2008-09-18

申请人： Masashi Yoshimura ,  Takatomo Sasaki ,  Yusuke Mori ,  Muneyuki Nishioka ,  Tomotaka Katsura ,  Tetsuo Kojima ,  Junichi Nishimae

发明人： Masashi Yoshimura ,  Takatomo Sasaki ,  Yusuke Mori ,  Muneyuki Nishioka ,  Tomotaka Katsura ,  Tetsuo Kojima ,  Junichi Nishimae

IPC分类号： G02F1/35 ,  H01S3/10

CPC分类号： G02F1/37 ,  G02F1/3551 ,  G02F2001/3505 ,  G02F2001/354

摘要： An optical wavelength conversion element includes a cesium-lithium-borate crystal processed into a 10-mm long optical element cut in an orientation that allows a fourth harmonic of a Nd:YAG laser to be generated. A transmittance (Ta) at 3589 cm−1 in an infrared transmission spectrum of the optical element is used as an index that indicates a content of water impurities in the crystal and is independent of a polarization direction. An actual measurement of the transmittance Ta is at least 1%, without taking into account loss at an optically polished surface of the crystal. A wavelength conversion device, a ultraviolet laser irradiation apparatus, a laser processing system, and a method of manufacturing an optical wavelength conversion element are also described.

摘要翻译： 光波长转换元件包括加工成允许产生Nd：YAG激光器的四次谐波的取向切割的10mm长的光学元件的铯 - 硼酸锂晶体。 光学元件的红外透射光谱中的3589cm -1处的透射率（Ta）被用作指示晶体中的水杂质含量并且与偏振方向无关的指标。 透射率Ta的实际测量值至少为1％，而不考虑在晶体的光学抛光表面处的损耗。 还描述了波长转换装置，紫外激光照射装置，激光加工系统和制造光波长转换元件的方法。

公开(公告)号：US20140029640A1

公开(公告)日：2014-01-30

申请号：US14110378

申请日：2011-04-08

申请人： Tetsuo Kojima ,  Hiroyuki Suzuki ,  Tatsuhide Takayama ,  Yoshio Saitou

发明人： Tetsuo Kojima ,  Hiroyuki Suzuki ,  Tatsuhide Takayama ,  Yoshio Saitou

IPC分类号： H01S3/094

CPC分类号： H01S3/094 ,  H01S3/025 ,  H01S3/0405 ,  H01S3/042 ,  H01S3/061 ,  H01S3/07 ,  H01S3/08054 ,  H01S3/08072 ,  H01S3/09408 ,  H01S3/094084 ,  H01S3/0941 ,  H01S3/1022 ,  H01S3/1611 ,  H01S3/1643 ,  H01S5/02415 ,  H01S5/02438

摘要： In a conventional solid-state laser device, uniformity of an excitation distribution around the axis of a solid-state laser medium is only considered, and symmetry of the excitation distribution in the optical axis direction of the solid-state laser device as a whole is not considered. Therefore, there has been a problem that it is difficult to generate a high-power and high-quality laser beam with high efficiency. In order to solve the problem, in the present invention, excitation modules 51, 52 of an even number is provided, along the optical axis of a solid-state laser beam 18, near the center of a resonator, and semiconductor lasers 21-28 serving as excitation light sources and solid-state laser media 11, 12 provided in the excitation module 51 or in the excitation module 52 are arranged to be symmetrical with respect to a virtual symmetry plane 61 located at a center gap between the excitation modules of the even number.

摘要翻译： 在现有的固态激光装置中，仅考虑固体激光介质轴的激发分布的均匀性，固体激光装置的光轴方向的激发分布的整体的对称性为 不考虑。 因此，存在难以以高效率生成高功率和高质量的激光束的问题。 为了解决这个问题，在本发明中，沿着固体激光束18的光轴，靠近谐振器的中心设置有偶数的激励模块51,52，半导体激光器21-28 用作激发光源的激光模块51或激励模块52中设置的固体激光介质11,12被布置成相对于虚拟对称平面61对称，虚拟对称平面61位于激光模块51的激励模块之间的中心间隙 偶数。

公开(公告)号：US09334331B2

公开(公告)日：2016-05-10

申请号：US13885421

申请日：2011-11-17

申请人： Tomoyuki Igawa ,  Zenjiro Sampei ,  Tetsuo Kojima ,  Tetsuhiro Soeda ,  Atsushi Muto ,  Takehisa Kitazawa ,  Yukiko Nishida ,  Chifumi Imai ,  Tsukasa Suzuki ,  Kazutaka Yoshihashi

发明人： Tomoyuki Igawa ,  Zenjiro Sampei ,  Tetsuo Kojima ,  Tetsuhiro Soeda ,  Atsushi Muto ,  Takehisa Kitazawa ,  Yukiko Nishida ,  Chifumi Imai ,  Tsukasa Suzuki ,  Kazutaka Yoshihashi

IPC分类号： C07K16/40 ,  C07K16/36

CPC分类号： C07K16/40 ,  C07K16/36 ,  C07K2317/31 ,  C07K2317/51 ,  C07K2317/56 ,  C07K2317/565 ,  C07K2317/75 ,  C07K2317/76 ,  C07K2317/94

摘要： Various bispecific antibodies that specifically bind to both blood coagulation factor IX/activated blood coagulation factor IX and blood coagulation factor X and functionally substitute for the cofactor function of blood coagulation factor VIII, that is, the function to promote activation of blood coagulation factor X by activated blood coagulation factor IX, were produced. From these antibodies, multispecific antigen-binding molecules having a high activity of functionally substituting for blood coagulation factor VIII were successfully discovered.

摘要翻译： 各种双特异性抗体特异性结合血液凝固因子IX /活化血液凝固因子IX和血液凝固因子X，并功能取代血液凝固因子VIII的辅因子功能，即促进凝血因子X活化的功能 活化血液凝固因子IX。 从这些抗体中，成功发现了具有高功能取代凝血因子VIII活性的多特异性抗原结合分子。

公开(公告)号：US08964414B2

公开(公告)日：2015-02-24

申请号：US13480503

申请日：2012-05-25

申请人： Tetsuo Kojima ,  Yuichiro Nozaki ,  Masafumi Makino ,  Takeshi Shinomiya ,  Tetsu Sugiura

发明人： Tetsuo Kojima ,  Yuichiro Nozaki ,  Masafumi Makino ,  Takeshi Shinomiya ,  Tetsu Sugiura

IPC分类号： H02M1/34 ,  H02M3/335

CPC分类号： H02M3/33576 ,  Y02B70/1433

摘要： A DC power supply including a resonant circuit on a secondary side of a transformer suppresses a surge voltage during power recovery of diodes constituting a rectifier circuit, correctly estimates a load current from a secondary current of the transformer, and adjusts supplied power when a load is light. The DC power supply includes a DC voltage source, a converter, a transformer, a rectifier circuit, a resonant circuit composed of a resonant switch and a resonant capacitor, a filter reactor, a filter capacitor, a snubber diode, a snubber capacitor, a load, first and second voltage sensors, a current sensor, and a controller for controlling gate pulses of semiconductor devices constituting a converter and the resonant switch and a signal for adjusting operation timings of A/D converters converting the signals of these sensors.

摘要翻译： 包括变压器次级侧的谐振电路的直流电源在构成整流电路的二极管的功率恢复期间抑制浪涌电压，正确地估计来自变压器的次级电流的负载电流，并且当负载为负载时，调整供电电力 光。 直流电源包括直流电压源，转换器，变压器，整流电路，由谐振开关和谐振电容器组成的谐振电路，滤波电抗器，滤波电容器，缓冲二极管，缓冲电容器，缓冲电容器 负载，第一和第二电压传感器，电流传感器和用于控制构成转换器的半导体器件的门脉冲和谐振开关的控制器，以及用于调整转换这些传感器的信号的A / D转换器的操作定时的信号。