Process for preparing a hyaluronic acid fraction having a low polydispersion index
    6.
    发明授权
    Process for preparing a hyaluronic acid fraction having a low polydispersion index 有权
    具有低多分散指数的透明质酸级分的制备方法

    公开(公告)号:US06232303B1

    公开(公告)日:2001-05-15

    申请号:US09426536

    申请日:1999-10-26

    IPC分类号: A61K3170

    CPC分类号: C08B37/0072

    摘要: A process for preparing a hyaluronic acid fraction having an average molecular weight comprised between 5000 and 300,000 and a polydispersion index lower than 1.7, comprising treating the starting high molecular weight hyaluronic acid, contemporaneously with sodium hypochlorite and ultrasounds.

    摘要翻译: 一种制备平均分子量在5000至300,000之间并且多分散指数低于1.7的透明质酸级分的方法,包括用次氯酸钠和超声波同时处理起始高分子量透明质酸。

    Ulcer treatment using choline esters of polysaccharides
    8.
    发明授权
    Ulcer treatment using choline esters of polysaccharides 失效
    使用多糖胆碱酯的溃疡治疗

    公开(公告)号:US5300493A

    公开(公告)日:1994-04-05

    申请号:US945495

    申请日:1992-09-16

    摘要: Acidic polysaccharide esters containing carboxylic groups are useful for protecting against and curing ulcers of the gastro-enteric system. These esters include choline esters with acidic polysaccharide selected from the group consisting of hyaluronic acid, alginic acid, gellan, oxidized cellulose, oxidized chitin, carboxy-hydrocarbyl-cellulose, carboxy-hydrocarbyl-starch and carboxy-hydrocarbyl-chitin, wherein the term hydrocarbyl means the residue of a hydrocarbon selected from the group consisting of by alkyl, aralkyl and cycloalkyl.

    摘要翻译: 含有羧基的酸性多糖酯可用于防止和治疗胃肠系统的溃疡。 这些酯包括选自透明质酸,海藻酸,结冷胶,氧化纤维素,氧化几丁质,羧基 - 烃基 - 纤维素,羧基 - 烃基 - 淀粉和羧基 - 烃基几丁质的酸性多糖的胆碱酯,其中术语烃基 是指选自烷基,芳烷基和环烷基的烃的残基。