-
1.发明授权
公开(公告)号：US5521164A
公开(公告)日：1996-05-28
申请号：US116268
申请日：1993-09-03
IPC分类号： A61K31/70 , A61K31/7028 , A61P25/00 , C07H1/08 , C07H15/04 , C07H15/10 , C07H15/12 , A61K35/30 , A61K31/715
摘要： The process of the invention relates to a process for the preparation of a ganglioside mixture, free from contaminants associated with non-conventional, life-threatening viruses, without altering the biological and pharmacological characteristics of the mixture on the central and peripheral nervous systems.
摘要翻译： 本发明的方法涉及一种制备神经节苷脂混合物的方法，所述神经节苷脂混合物没有与非传统的危及生命的病毒相关的污染物，而不改变中枢和周围神经系统上混合物的生物学和药理学特性。
-
公开(公告)号：US5210185A
公开(公告)日：1993-05-11
申请号：US322729
申请日：1989-03-13
IPC分类号： C12P21/00 , A61K38/00 , A61P25/28 , C07K1/18 , C07K1/22 , C07K14/435 , C07K14/48 , C07K14/52
CPC分类号： C07K14/48 , A61K38/00 , Y10S530/851
摘要： The present invention is directed to a method for the isolation of Human Nerve Growth Factor (HNGF) from human placenta. More particularly, the invention is directed to the method of isolation of the .beta.-subunit of Human Nerve Growth Factor and Compositions containing the same for the treatment of neuropathological conditions.
-
公开(公告)号：US5332809A
公开(公告)日：1994-07-26
申请号：US833517
申请日：1992-02-11
IPC分类号： A23L1/30 , A61K8/40 , A61K8/41 , A61K8/49 , A61K8/64 , A61K8/72 , A61K8/73 , A61K8/96 , A61L15/28 , A61L31/00 , C08B37/00 , C07H13/02
CPC分类号： C08B37/006
摘要： The present invention is directed to total and partial esters of gellan in which the esterifying alcohol component is derived from aliphatic, araliphatic, cycloaliphatic or heterocyclic alcohols, and salts of said partial esters with inorganic or organic bases, and compositions containing the same.
摘要翻译： 本发明涉及结构甘醇的全部和部分酯，其中酯化醇组分衍生自脂族，芳脂族，脂环族或杂环醇，所述偏酯与无机或有机碱的盐，以及含有它们的组合物。
-
公开(公告)号：US5457034A
公开(公告)日：1995-10-10
申请号：US156792
申请日：1993-11-24
IPC分类号： C12N15/09 , A61K31/702 , A61K38/00 , A61K38/22 , A61P25/00 , A61P25/28 , A61P37/00 , C07K14/005 , C07K14/195 , C07K14/48 , C07K14/52 , C12N5/10 , C12N15/16 , C12N15/18 , C12P21/00 , C12P21/02 , C12R1/91 , C12P21/06 , C07H17/00 , C07K14/00 , C12N15/00
摘要： This invention relates to a process for obtaining, from transformed cells, the polypeptide called nerve growth factor (.beta.-NGF), and more precisely to the process for obtaining, by recombinant DNA technology using genetic constructions insertible in appropriate eukaryotic cell lines, the biologically active human mature form (.beta.-subunit).
摘要翻译： 本发明涉及一种从转化细胞获得称为神经生长因子（β-NGF）的多肽的方法，更确切地说，涉及通过使用可插入适当真核生物细胞系的遗传构建体的重组DNA技术获得生物学方法 活性人成熟形式（β亚基）。
-
5.发明授权Purification of nerve growth factor (.beta. subunit) by subunit exchange chromatography 失效通过子交换色谱纯化神经生长因子（（BETA）亚基）
-
6.发明授权Biodegradable and bioabsorbable guide channels for use in nerve treatment and regeneration 失效用于神经治疗和再生的可生物降解和生物可吸收的引导通道
公开(公告)号：US5735863A
公开(公告)日：1998-04-07
申请号：US104025
申请日：1994-05-24
IPC分类号： A61L31/00 , A61B17/11 , A61F2/00 , A61F2/02 , A61F2/04 , A61L31/04 , A61L31/12 , A61L31/14 , A61L31/16 , A61B17/00
CPC分类号： A61L31/148 , A61L31/042 , A61L31/129 , A61B17/1128 , A61F2/0077 , A61F2/04 , A61F2210/0004 , A61L2430/32
摘要： The present invention is drawn to medical devices comprised of biodegradable guide channels for use in repair and regeneration of nerve tissue. The guide channels are comprised of threads embedded in a matrix and coextruded with active factors wherein both the matrix and the threads are comprised of biocompatible and bioabsorbable esters of hyaluronic acid.
摘要翻译： PCT No.PCT / EP92 / 00285 Sec。 371日期：1994年5月24日 102（e）日期1994年5月24日PCT提交1992年2月10日PCT公布。 出版物WO92 / 13579 日本1992年8月20日本发明涉及由可用于修复和再生神经组织的生物可降解导向通道构成的医疗器械。 引导通道由嵌入基质中的螺纹组成并与活性因子共挤出，其中基质和螺纹均由透明质酸的生物相容性和生物可吸收的酯组成。
-
7.发明授权Biomaterials, their preparation by electrospinning and their use in the biomedical and surgical field 有权生物材料，它们通过静电纺丝制备及其在生物医学和外科领域的应用公开(公告)号：US08865964B2
公开(公告)日：2014-10-21
申请号：US13056541
申请日：2009-07-24
CPC分类号： A61L27/60 , Y10T442/3065 , Y10T442/614 , Y10T442/626
摘要： There is described a new non-woven fabric produced with the electrospinning technique, and the use thereof as new biomaterial for the biomedical and surgical field.
摘要翻译： 描述了一种用静电纺丝技术生产的新型无纺织物，并将其用作生物医学和外科领域的新生物材料。
-
8.发明授权公开(公告)号：US08147811B1
公开(公告)日：2012-04-03
申请号：US10019387
申请日：2000-06-29
IPC分类号： A61K8/18
CPC分类号： A61K31/728 , A61K31/715 , A61L15/28 , A61L15/44 , A61L17/005 , A61L17/10 , A61L31/042 , A61L31/16 , A61L2300/00 , A61L2300/236 , A61L2300/404 , A61L2300/414 , A61L2300/45 , A61K31/00 , A61K2300/00 , C08L5/08
摘要： Use of hyaluronic acid derivatives for the preparation of biomaterials for the prevention of the formation and the treatment of cutaneous scars, wherein the hyaluronic acid derivatives are optionally combined with pharmacologically or biologically active compounds.
摘要翻译： 透明质酸衍生物用于制备用于预防皮肤瘢痕形成和治疗的生物材料的透明质酸衍生物，其中任选地与药理学或生物活性化合物组合。
-
9.发明授权Use of a biological material containing three-dimensional scaffolds of hyaluronic acid derivatives for the preparation of implants in arthroscopy and kit for instruments for implanting said biological material by arthroscopy 有权使用含有透明质酸衍生物的立体支架的生物材料用于在关节镜中制备植入物，以及用于通过关节镜检查植入所述生物材料的器械的试剂盒公开(公告)号：US07722616B2
公开(公告)日：2010-05-25
申请号：US10250408
申请日：2001-12-27
CPC分类号： A61L27/3804 , A61L27/20 , A61L27/3852 , C08L5/08
摘要： The invention relates to use of a biological material containing cells supported on three-dimensional scaffolds containing at least one hyaluronic acid derivative for the preparation of grafts suitable for application by arthroscopy, and a kit of surgical instruments for implanting said biological material by arthroscopy.
摘要翻译： 本发明涉及包含支持在含有至少一种透明质酸衍生物的三维支架上的细胞的生物材料用于制备适于通过关节镜检查应用的移植物的用途，以及用于通过关节镜检查植入所述生物材料的外科器械套件的用途。
-
10.发明授权Injectable carrier formulations of hyaluronic acid derivatives for delivery of osteogenic proteins 失效用于输送成骨蛋白质的透明质酸衍生物的可注射载体制剂公开(公告)号：US07608580B2
公开(公告)日：2009-10-27
申请号：US11624463
申请日：2007-01-18
申请人： Hyun Kim , Rebecca Li , Alessandra Pavesio , Lanfranco Callegaro , Howard Seeherman , John Wozney
发明人： Hyun Kim , Rebecca Li , Alessandra Pavesio , Lanfranco Callegaro , Howard Seeherman , John Wozney
IPC分类号： A61K38/16
CPC分类号： A61K9/0024 , A61K9/0019 , A61K38/1875 , A61K47/26 , A61K47/36 , A61L27/20 , A61L27/227 , A61L27/46 , A61L2300/414 , A61L2400/06 , A61K2300/00 , C08L5/08
摘要： An injectable formulation is disclosed for delivery of osteogenic proteins. The formulation comprises a pharmaceutically acceptable admixture of an osteogenic protein; and formulations comprising osteogenic protein, hyaluronic acid derivatives and tricalcium phosphate are also disclosed. Methods for formulating porous injectable gels and pastes from hyaluronic acid are also disclosed.
摘要翻译： 公开了用于递送成骨蛋白质的可注射制剂。 该制剂包含成骨蛋白的药学上可接受的混合物; 并且还公开了包含成骨蛋白，透明质酸衍生物和磷酸三钙的制剂。 还公开了从透明质酸配制多孔可注射凝胶和糊剂的方法。
-
-
-
-
-
-
-
-
-
搜索结果
64 条记录 (耗时 0.023 秒)
