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公开(公告)号:US20170233834A1
公开(公告)日:2017-08-17
申请号:US15433650
申请日:2017-02-15
Applicant: MODERN MEADOW, INC
Inventor: Brendan Patrick PURCELL , David Thomas Williamson , Francoise Suzanne Marga , Susan J. Schofer , Darryl Miles Cassingham , Stephen M. Spinella , Amy Congdon
IPC: C14C9/00 , D04H1/4382 , C07K14/78 , C14C9/02 , D06P3/32
CPC classification number: C08J3/24 , B32B1/08 , B32B3/266 , B32B5/022 , B32B5/024 , B32B5/026 , B32B5/26 , B32B7/12 , B32B9/025 , B32B15/02 , B32B15/14 , B32B23/10 , B32B27/12 , B32B29/02 , B32B2250/02 , B32B2250/03 , B32B2250/20 , B32B2250/40 , B32B2250/42 , B32B2255/02 , B32B2255/26 , B32B2262/0207 , B32B2262/0261 , B32B2262/0269 , B32B2262/0276 , B32B2262/0292 , B32B2262/04 , B32B2262/062 , B32B2262/065 , B32B2262/067 , B32B2262/08 , B32B2262/10 , B32B2262/101 , B32B2262/103 , B32B2262/106 , B32B2262/14 , B32B2264/105 , B32B2307/202 , B32B2307/208 , B32B2307/308 , B32B2307/4026 , B32B2307/422 , B32B2307/50 , B32B2307/51 , B32B2307/54 , B32B2307/5825 , B32B2307/708 , B32B2307/7265 , B32B2437/00 , B32B2437/02 , B32B2437/04 , B32B2439/46 , B32B2451/00 , B32B2457/00 , B32B2471/00 , B32B2479/00 , B32B2519/00 , B32B2571/00 , B32B2601/00 , B32B2605/003 , B32B2605/08 , B32B2605/12 , B32B2605/18 , C07K14/78 , C08J2389/06 , C14C9/00 , C14C9/02 , C14C13/00 , D01C3/00 , D01F4/00 , D04H1/00 , D04H1/4382 , D04H13/00 , D06M15/05 , D06M15/15 , D06M23/16 , D06M2101/06 , D06N3/00 , D06N3/0018 , D06N7/0097 , D06N2201/06 , D06N2203/02 , D06P3/32
Abstract: Described herein is a method for producing a biofabricated material from collagen or collagen-like proteins which are recombinantly produced and which contain substantially no 3-hydroxyproline. The collagen or collagen-like proteins are isolated from animal sources, or produced by recombinant DNA techniques or by chemical synthesis. The collagen or collagen-like proteins are fibrillated, crosslinked, dehydrated and lubricated thus forming the biofabricated material having a substantially uniform network of collagen fibrils.
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公开(公告)号:US20170233944A1
公开(公告)日:2017-08-17
申请号:US15433566
申请日:2017-02-15
Applicant: MODERN MEADOW, INC.
Inventor: Brendan Patrick PURCELL , David Thomas WILLIAMSON , Lixin DAI , Darryl Miles CASSINGHAM , Stephen M. SPINELLA , Amy CONGDON
IPC: D06N3/00
CPC classification number: C08J3/24 , B32B1/08 , B32B3/266 , B32B5/022 , B32B5/024 , B32B5/026 , B32B5/26 , B32B7/12 , B32B9/025 , B32B15/02 , B32B15/14 , B32B23/10 , B32B27/12 , B32B29/02 , B32B2250/02 , B32B2250/03 , B32B2250/20 , B32B2250/40 , B32B2250/42 , B32B2255/02 , B32B2255/26 , B32B2262/0207 , B32B2262/0261 , B32B2262/0269 , B32B2262/0276 , B32B2262/0292 , B32B2262/04 , B32B2262/062 , B32B2262/065 , B32B2262/067 , B32B2262/08 , B32B2262/10 , B32B2262/101 , B32B2262/103 , B32B2262/106 , B32B2262/14 , B32B2264/105 , B32B2307/202 , B32B2307/208 , B32B2307/308 , B32B2307/4026 , B32B2307/422 , B32B2307/50 , B32B2307/51 , B32B2307/54 , B32B2307/5825 , B32B2307/708 , B32B2307/7265 , B32B2437/00 , B32B2437/02 , B32B2437/04 , B32B2439/46 , B32B2451/00 , B32B2457/00 , B32B2471/00 , B32B2479/00 , B32B2519/00 , B32B2571/00 , B32B2601/00 , B32B2605/003 , B32B2605/08 , B32B2605/12 , B32B2605/18 , C07K14/78 , C08J2389/06 , C14C9/00 , C14C9/02 , C14C13/00 , D01C3/00 , D01F4/00 , D04H1/00 , D04H1/4382 , D04H13/00 , D06M15/05 , D06M15/15 , D06M23/16 , D06M2101/06 , D06N3/00 , D06N3/0018 , D06N7/0097 , D06N2201/06 , D06N2203/02 , D06P3/32
Abstract: A biofabricated material comprising a network of crosslinked collagen fibrils produced from recombinant collagen that contains substantially no 3-hydroxyproline residues is disclosed. This material is composed of collagen which is also a major component of natural leather and is produced by a process of fibrillation of collagen molecules into fibrils, crosslinking the fibrils and lubricating the crosslinked fibrils. Unlike natural leathers, this biofabricated material exhibits non-anisotropic (not directionally dependent) physical properties, for example, a sheet of biofabricated material can have substantially the same elasticity or tensile strength when stretched or stressed in different directions. Unlike natural leather, it has a uniform texture that facilitates uniform uptake of dyes and coatings. Aesthetically, it produces a uniform and consistent grain for ease of manufacturability. It can have substantially identical grain, texture and other aesthetic properties on both sides distinct from natural leather where the grain increases from one side (e.g., distal surface) to the other (proximal inner layers).
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公开(公告)号:US20200207932A1
公开(公告)日:2020-07-02
申请号:US16673603
申请日:2019-11-04
Applicant: Modern Meadow, Inc.
Inventor: Brendan Patrick PURCELL , David Thomas WILLIAMSON , Suzanne LEE , Amy CONGDON
IPC: C08J3/24 , D06M15/05 , D04H1/00 , D06N3/00 , D01C3/00 , D04H1/4382 , C14C9/02 , C14C9/00 , C07K14/78 , D06P3/32 , D04H13/00 , C14C13/00 , B32B3/26 , B32B1/08 , B32B29/02 , B32B27/12 , B32B23/10 , B32B15/14 , B32B15/02 , B32B9/02 , B32B7/12 , B32B5/02 , D06N7/00 , D06M15/15 , B32B5/26 , D01F4/00
Abstract: The invention is directed to a method for producing a composite material comprising a biofabricated material and a secondary component. The secondary component may be a porous material, such as a sheet of paper, cellulose, or fabric that has been coated or otherwise contacted with the biofabricated material. The biofabricated material comprises a uniform network of crosslinked collagen fibrils and provides strength, elasticity and an aesthetic appearance to the composite material.
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公开(公告)号:US20190144957A1
公开(公告)日:2019-05-16
申请号:US16189692
申请日:2018-11-13
Applicant: MODERN MEADOW, INC.
Inventor: Brendan Patrick PURCELL , Suzanne LEE , Lixin DAI , Katherine Amy CONGDON , Stephen M. SPINELLA , Chi Man NG
Abstract: The invention herein provides biofabricated materials having zonal properties and methods of making biofabricated materials having zonal properties.
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公开(公告)号:US20190024303A1
公开(公告)日:2019-01-24
申请号:US15713300
申请日:2017-09-22
Applicant: Modern Meadow, Inc.
Inventor: Suzanne LEE , Catherine Amy CONGDON , Morgan SCHNEIDER , Brendan Patrick PURCELL , Callie McBride CLAYTON , Natalia KRASNODEBSKA , Nicole MUSE
Abstract: The invention herein provides biofabricated leather materials, solutions comprising collagen that can be used to create biofabricated leather materials, articles comprising biofabricated leather materials applied to portions of a substrate in a pattern or a design such a lace like pattern, and/or that serve to join end portions of one or more substrates, e.g., to replace stitching and/or adhesives, and methods thereof.
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公开(公告)号:US20180230644A1
公开(公告)日:2018-08-16
申请号:US15761209
申请日:2016-09-21
Applicant: MODERN MEADOW, INC.
Inventor: Brendan Patrick PURCELL , Gabor FORGACS
CPC classification number: D06N3/0006 , C12N5/0068 , C12N2533/50 , C14C3/06 , D06N3/00 , D06N3/0011
Abstract: Engineered, reinforced leather materials (engineered leathers) including a composite of a fibrous matrix that has been tanned to allow crosslinking of the fibrous matrix to the collagen formed by cultured cells (e.g., fibroblasts). These engineered leathers may be referred to as fiber-reinforced biological tissue composites. Also described herein are methods of making such fiber-reinforced biological tissue composites.
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公开(公告)号:US20170233837A1
公开(公告)日:2017-08-17
申请号:US15433693
申请日:2017-02-15
Applicant: MODERN MEADOW, INC.
Inventor: Brendan Patrick PURCELL , David Thomas Williamson , Suzanne Lee , Amy Congdon
CPC classification number: C08J3/24 , B32B1/08 , B32B3/266 , B32B5/022 , B32B5/024 , B32B5/026 , B32B5/26 , B32B7/12 , B32B9/025 , B32B15/02 , B32B15/14 , B32B23/10 , B32B27/12 , B32B29/02 , B32B2250/02 , B32B2250/03 , B32B2250/20 , B32B2250/40 , B32B2250/42 , B32B2255/02 , B32B2255/26 , B32B2262/0207 , B32B2262/0261 , B32B2262/0269 , B32B2262/0276 , B32B2262/0292 , B32B2262/04 , B32B2262/062 , B32B2262/065 , B32B2262/067 , B32B2262/08 , B32B2262/10 , B32B2262/101 , B32B2262/103 , B32B2262/106 , B32B2262/14 , B32B2264/105 , B32B2307/202 , B32B2307/208 , B32B2307/308 , B32B2307/4026 , B32B2307/422 , B32B2307/50 , B32B2307/51 , B32B2307/54 , B32B2307/5825 , B32B2307/708 , B32B2307/7265 , B32B2437/00 , B32B2437/02 , B32B2437/04 , B32B2439/46 , B32B2451/00 , B32B2457/00 , B32B2471/00 , B32B2479/00 , B32B2519/00 , B32B2571/00 , B32B2601/00 , B32B2605/003 , B32B2605/08 , B32B2605/12 , B32B2605/18 , C07K14/78 , C08J2389/06 , C14C9/00 , C14C9/02 , C14C13/00 , D01C3/00 , D01F4/00 , D04H1/00 , D04H1/4382 , D04H13/00 , D06M15/05 , D06M15/15 , D06M23/16 , D06M2101/06 , D06N3/00 , D06N3/0018 , D06N7/0097 , D06N2201/06 , D06N2203/02 , D06P3/32
Abstract: The invention is directed to a composite material comprising a biofabricated material and a secondary component. The secondary component may be a porous material, such as a sheet of paper, cellulose, or fabric that has been coated or otherwise contacted with the biofabricated material. The biofabricated material comprises a uniform network of crosslinked collagen fibrils and provides strength, elasticity and an aesthetic appearance to the composite material.
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公开(公告)号:US20210023764A1
公开(公告)日:2021-01-28
申请号:US16978545
申请日:2019-03-05
Applicant: Modern Meadow, Inc.
Inventor: Nicholas John BABIN , Kevin SPARKS , Stephen SPINELLA , Brendan Patrick PURCELL
IPC: B29C51/00 , C08K5/3415 , C08J5/18 , B29C45/00 , B29C51/10
Abstract: Described herein are three dimensionally shaped biofabricated materials and method of making three dimensionally shaped biofabricated materials.
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公开(公告)号:US20190203000A1
公开(公告)日:2019-07-04
申请号:US16358299
申请日:2019-03-19
Applicant: MODERN MEADOW, INC.
Inventor: Brendan Patrick PURCELL , David Thomas WILLIAMSON , Lixin DAI , Darryl Miles CASSINGHAM , Stephen M. SPINELLA
IPC: C08J3/24 , B32B3/26 , D06P3/32 , B32B29/02 , B32B27/12 , B32B23/10 , B32B15/14 , B32B15/02 , B32B9/02 , B32B7/12 , B32B5/02 , D01F4/00 , D04H1/00 , D06N3/00 , D04H1/4382 , C14C9/02 , C14C9/00 , C07K14/78 , D04H13/00 , C14C13/00 , D06N7/00 , D06M15/15 , B32B5/26 , D06M15/05 , D01C3/00 , B32B1/08
CPC classification number: C08J3/24 , B32B1/08 , B32B3/266 , B32B5/022 , B32B5/024 , B32B5/026 , B32B5/26 , B32B7/12 , B32B9/025 , B32B15/02 , B32B15/14 , B32B23/10 , B32B27/12 , B32B29/02 , B32B2250/02 , B32B2250/03 , B32B2250/20 , B32B2250/40 , B32B2250/42 , B32B2255/02 , B32B2255/26 , B32B2262/0207 , B32B2262/0261 , B32B2262/0269 , B32B2262/0276 , B32B2262/0292 , B32B2262/04 , B32B2262/062 , B32B2262/065 , B32B2262/067 , B32B2262/08 , B32B2262/10 , B32B2262/101 , B32B2262/103 , B32B2262/106 , B32B2262/14 , B32B2264/105 , B32B2307/202 , B32B2307/208 , B32B2307/308 , B32B2307/4026 , B32B2307/422 , B32B2307/50 , B32B2307/51 , B32B2307/54 , B32B2307/5825 , B32B2307/708 , B32B2307/7265 , B32B2437/00 , B32B2437/02 , B32B2437/04 , B32B2439/46 , B32B2451/00 , B32B2457/00 , B32B2471/00 , B32B2479/00 , B32B2519/00 , B32B2571/00 , B32B2601/00 , B32B2605/003 , B32B2605/08 , B32B2605/12 , B32B2605/18 , C07K14/78 , C08J2389/06 , C14C9/00 , C14C9/02 , C14C13/00 , D01C3/00 , D01F4/00 , D04H1/00 , D04H1/4382 , D04H13/00 , D06M15/05 , D06M15/15 , D06M23/16 , D06M2101/06 , D06N3/00 , D06N3/0018 , D06N7/0097 , D06N2201/06 , D06N2203/02 , D06P3/32
Abstract: A biofabricated material containing a network of crosslinked collagen fibrils is disclosed. This material is composed of collagen which is also a major component of natural leather and is produced by a process of fibrillation of collagen molecules into fibrils, crosslinking the fibrils and lubricating the crosslinked fibrils. Unlike natural leathers, this biofabricated material exhibits non-anisotropic (not directionally dependent) physical properties, for example, a sheet of biofabricated material can have substantially the same elasticity or tensile strength when stretched or stressed in different directions. Unlike natural leather, it has a uniform texture that facilitates uniform uptake of dyes and coatings. Aesthetically, it produces a uniform and consistent grain for ease of manufacturability. It can have substantially identical grain, texture and other aesthetic properties on both sides distinct from natural leather where the grain increases from one side (e.g., distal surface) to the other (proximal inner layers).
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公开(公告)号:US20170233945A1
公开(公告)日:2017-08-17
申请号:US15433675
申请日:2017-02-15
Applicant: MODERN MEADOW, INC.
Inventor: Brendan Patrick PURCELL , David Thomas WILLIAMSON , Suzanne LEE , Amy CONGDON
Abstract: The invention is directed to a method for producing a composite material comprising a biofabricated material and a secondary component. The secondary component may be a porous material, such as a sheet of paper, cellulose, or fabric that has been coated or otherwise contacted with the biofabricated material. The biofabricated material comprises a uniform network of crosslinked collagen fibrils and provides strength, elasticity and an aesthetic appearance to the composite material.
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