公开(公告)号：US08628949B2

公开(公告)日：2014-01-14

申请号：US12364825

申请日：2009-02-03

申请人： Makoto Kameyama ,  Nobuyuki Okamura ,  Tadashi Okamoto

发明人： Makoto Kameyama ,  Nobuyuki Okamura ,  Tadashi Okamoto

IPC分类号： C12M1/36

CPC分类号： B01L3/0268 ,  B01J19/0046 ,  B01J2219/0036 ,  B01J2219/00378 ,  B01J2219/00385 ,  B01J2219/00527 ,  B01J2219/00605 ,  B01J2219/00659 ,  B01J2219/00698 ,  B01J2219/0072 ,  B01J2219/00722 ,  B01J2219/00725 ,  B01J2219/0074 ,  B01L2200/0684 ,  B01L2200/142 ,  C40B40/06 ,  C40B40/10 ,  C40B60/14

摘要： An apparatus for producing a probe carrier in which ambient humidity for a plurality of nozzles of a liquid ejection device for ejecting droplets of solutions containing probes to the surface of a carrier is controlled to 50% or more, preferably 60% or more. A part of solution supply passages to the plurality of nozzles is constructed from gas permeable membranes permitting gas-liquid separation under reduced pressure. These gas permeable membrane portions are gathered and altogether placed under reduced pressure to remove air bubbles from the respective solutions supplied to the plural nozzles and decrease the amount of a dissolved gas, which causes air bubbles to be generated.

摘要翻译： 一种用于制造探针载体的装置，其中将用于将含有探针的溶液的液滴喷射到载体表面的液体喷射装置的多个喷嘴的环境湿度控制在50％以上，优选为60％以上。 多个喷嘴的溶液供给通道的一部分由气体渗透膜构成，允许在减压下气液分离。 将这些透气膜部分聚集在一起并放置在减压下以从供应给多个喷嘴的各溶液中除去气泡并减少溶解气体的量，从而产生气泡。

公开(公告)号：US20090143251A1

公开(公告)日：2009-06-04

申请号：US12364825

申请日：2009-02-03

申请人： Makoto Kameyama ,  Nobuyuki Okamura ,  Tadashi Okamoto

发明人： Makoto Kameyama ,  Nobuyuki Okamura ,  Tadashi Okamoto

IPC分类号： C40B60/14

CPC分类号： B01L3/0268 ,  B01J19/0046 ,  B01J2219/0036 ,  B01J2219/00378 ,  B01J2219/00385 ,  B01J2219/00527 ,  B01J2219/00605 ,  B01J2219/00659 ,  B01J2219/00698 ,  B01J2219/0072 ,  B01J2219/00722 ,  B01J2219/00725 ,  B01J2219/0074 ,  B01L2200/0684 ,  B01L2200/142 ,  C40B40/06 ,  C40B40/10 ,  C40B60/14

摘要： An apparatus for producing a probe carrier in which ambient humidity for a plurality of nozzles of a liquid ejection device for ejecting droplets of solutions containing probes to the surface of a carrier is controlled to 50% or more, preferably 60% or more. A part of solution supply passages to the plurality of nozzles is constructed from gas permeable membranes permitting gas-liquid separation under reduced pressure. These gas permeable membrane portions are gathered and altogether placed under reduced pressure to remove air bubbles from the respective solutions supplied to the plural nozzles and decrease the amount of a dissolved gas, which causes air bubbles to be generated.

摘要翻译： 一种用于制造探针载体的装置，其中将用于将含有探针的溶液的液滴喷射到载体表面的液体喷射装置的多个喷嘴的环境湿度控制在50％以上，优选为60％以上。 多个喷嘴的溶液供给通道的一部分由气体渗透膜构成，允许在减压下气液分离。 将这些透气膜部分聚集在一起并放置在减压下以从供应到多个喷嘴的各溶液中除去气泡，并减少产生气泡的溶解气体的量。

公开(公告)号：US20050158738A1

公开(公告)日：2005-07-21

申请号：US10958348

申请日：2004-10-06

申请人： Nobuyuki Okamura ,  Tadashi Okamoto ,  Makoto Kameyama

发明人： Nobuyuki Okamura ,  Tadashi Okamoto ,  Makoto Kameyama

IPC分类号： B01J19/00 ,  B01L3/00 ,  B05D3/00 ,  C12M1/34 ,  C12Q1/68 ,  C40B40/06 ,  C40B40/10 ,  C40B40/12 ,  C40B60/14

CPC分类号： B01J19/0046 ,  B01J2219/00317 ,  B01J2219/00378 ,  B01J2219/00432 ,  B01J2219/00497 ,  B01J2219/0056 ,  B01J2219/00576 ,  B01J2219/00585 ,  B01J2219/00596 ,  B01J2219/00605 ,  B01J2219/00612 ,  B01J2219/00626 ,  B01J2219/00635 ,  B01J2219/00659 ,  B01J2219/00677 ,  B01J2219/00707 ,  B01J2219/00722 ,  B01J2219/00725 ,  B01J2219/00729 ,  B01J2219/00731 ,  B01L3/5085 ,  C40B40/06 ,  C40B40/10 ,  C40B40/12 ,  C40B60/14

摘要： A carrier having indexes in a probe non-fixing region is used and solutions containing probes are applied to respective specific positions on the carrier by referring to said indexes and fixed. The position of a target compound that is specifically bonded to a probe fixed to a probe carrier manufactured by a method according to the invention can be accurately and quickly detected by referring to the indexes.

摘要翻译： 使用具有探针非固定区域中的索引的载体，并且将包含探针的溶液通过参考所述索引应用于载体上的各个特定位置并固定。 通过参照这些指标，可以准确，快速地检测特异性地结合固定于通过本发明的方法制造的探针载体的探针的探针的目标化合物的位置。

公开(公告)号：US07684943B2

公开(公告)日：2010-03-23

申请号：US11687946

申请日：2007-03-19

申请人： Nobuyuki Okamura ,  Makoto Kameyama ,  Tadashi Okamoto

发明人： Nobuyuki Okamura ,  Makoto Kameyama ,  Tadashi Okamoto

IPC分类号： G06F19/00

CPC分类号： C12Q1/6837 ,  B01J19/0046 ,  B01J2219/00378 ,  B01J2219/00549 ,  B01J2219/00605 ,  B01J2219/00659 ,  B01J2219/00662 ,  B01J2219/00693 ,  B01J2219/00695 ,  B01J2219/0072 ,  B01J2219/00722 ,  C40B40/06 ,  C40B60/14 ,  C40B70/00 ,  G01N2035/00752 ,  Y10T436/11 ,  Y10T436/112499 ,  Y10T436/113332 ,  Y10T436/2575

摘要： A method for appropriately managing the quality and distribution of a probe carrier. Probe carriers manufactured by a probe carrier manufacturing apparatus having ejecting portions for ejecting probe solutions, each containing a probe, which can be specifically coupled with a target substance, for applying the probe solution on a carrier, and a plurality of probe tanks storing mutually different probe solutions for supplying ejecting portions. Each probe tank is labeled with the bar-code. The labeled bar-code is read by the bar-code reader. On the basis of the read bar-code, the probe solution stored in the probe tank is identified. On the other hand, the probe tank is mounted on the ejecting portion.

摘要翻译： 一种适当管理探头载体的质量和分布的方法。 由具有用于喷射探针溶液的喷射部分的探针载体制造的探针载体，每个探针溶液包含可与靶物质特异性结合的探针，用于将探针溶液施加在载体上，以及存储相互不同的多个探针罐 用于提供喷射部分的探针溶液。 每个探针槽都标有条形码。 标签条码由条形码阅读器读取。 根据读取的条形码，识别存储在探针罐中的探针溶液。 另一方面，探针箱安装在喷射部上。

公开(公告)号：US20070160505A1

公开(公告)日：2007-07-12

申请号：US11687946

申请日：2007-03-19

申请人： Nobuyuki Okamura ,  Makoto Kameyama ,  Tadashi Okamoto

发明人： Nobuyuki Okamura ,  Makoto Kameyama ,  Tadashi Okamoto

IPC分类号： B01L9/00

CPC分类号： C12Q1/6837 ,  B01J19/0046 ,  B01J2219/00378 ,  B01J2219/00549 ,  B01J2219/00605 ,  B01J2219/00659 ,  B01J2219/00662 ,  B01J2219/00693 ,  B01J2219/00695 ,  B01J2219/0072 ,  B01J2219/00722 ,  C40B40/06 ,  C40B60/14 ,  C40B70/00 ,  G01N2035/00752 ,  Y10T436/11 ,  Y10T436/112499 ,  Y10T436/113332 ,  Y10T436/2575

摘要： A method for appropriately managing the quality and distribution of a probe carrier. Probe carriers manufactured by a probe carrier manufacturing apparatus having ejecting portions for ejecting probe solutions, each containing a probe, which can be specifically coupled with a target substance, for applying the probe solution on a carrier, and a plurality of probe tanks storing mutually different probe solutions for supplying ejecting portions. Each probe tank is labeled with the bar-code. The labeled bar-code is read by the bar-code reader. On the basis of the read bar-code, the probe solution stored in the probe tank is identified. On the other hand, the probe tank is mounted on the ejecting portion.

摘要翻译： 一种适当管理探头载体的质量和分布的方法。 由具有用于喷射探针溶液的喷射部分的探针载体制造的探针载体，每个探针溶液包含可与靶物质特异性结合的探针，用于将探针溶液施加在载体上，以及存储相互不同的多个探针罐 用于提供喷射部分的探针溶液。 每个探针槽都标有条形码。 标签条码由条形码阅读器读取。 根据读取的条形码，识别存储在探针罐中的探针溶液。 另一方面，探针箱安装在喷射部上。

公开(公告)号：US06852524B2

公开(公告)日：2005-02-08

申请号：US10133675

申请日：2002-04-29

申请人： Nobuyuki Okamura ,  Tadashi Okamoto ,  Makoto Kameyama

发明人： Nobuyuki Okamura ,  Tadashi Okamoto ,  Makoto Kameyama

IPC分类号： B01J19/00 ,  B01L3/00 ,  B05D3/00 ,  C12M1/34 ,  C12Q1/68 ,  C40B40/06 ,  C40B40/10 ,  C40B40/12 ,  C40B60/14 ,  G01N21/00

CPC分类号： B01J19/0046 ,  B01J2219/00317 ,  B01J2219/00378 ,  B01J2219/00432 ,  B01J2219/00497 ,  B01J2219/0056 ,  B01J2219/00576 ,  B01J2219/00585 ,  B01J2219/00596 ,  B01J2219/00605 ,  B01J2219/00612 ,  B01J2219/00626 ,  B01J2219/00635 ,  B01J2219/00659 ,  B01J2219/00677 ,  B01J2219/00707 ,  B01J2219/00722 ,  B01J2219/00725 ,  B01J2219/00729 ,  B01J2219/00731 ,  B01L3/5085 ,  C40B40/06 ,  C40B40/10 ,  C40B40/12 ,  C40B60/14

摘要： A carrier having indexes in a probe non-fixing region is used and solutions containing probes are applied to respective specific positions on the carrier by referring to said indexes and fixed. The position of a target compound that is specifically bonded to a probe fixed to a probe carrier manufactured by a method according to the invention can be accurately and quickly detected by referring to the indexes.

公开(公告)号：US07216042B2

公开(公告)日：2007-05-08

申请号：US10105312

申请日：2002-03-26

申请人： Nobuyuki Okamura ,  Makoto Kameyama ,  Tadashi Okamoto

发明人： Nobuyuki Okamura ,  Makoto Kameyama ,  Tadashi Okamoto

IPC分类号： G06F19/00

CPC分类号： C12Q1/6837 ,  B01J19/0046 ,  B01J2219/00378 ,  B01J2219/00549 ,  B01J2219/00605 ,  B01J2219/00659 ,  B01J2219/00662 ,  B01J2219/00693 ,  B01J2219/00695 ,  B01J2219/0072 ,  B01J2219/00722 ,  C40B40/06 ,  C40B60/14 ,  C40B70/00 ,  G01N2035/00752 ,  Y10T436/11 ,  Y10T436/112499 ,  Y10T436/113332 ,  Y10T436/2575

摘要： A method for appropriately managing the quality and distribution of a probe carrier. Probe carriers manufactured by a probe carrier manufacturing apparatus having ejecting portions for ejecting probe solutions, each containing a probe, which can be specifically coupled with a target substance, for applying the probe solution on a carrier, and a plurality of probe tanks storing mutually different probe solutions for supplying ejecting portions. Each probe tank is labeled with the bar-code. The labeled bar-code is read by the bar-code reader. On the basis of the read bar-code, the probe solution stored in the probe tank is identified. On the other hand, the probe tank is mounted on the ejecting portion.

摘要翻译： 一种适当管理探头载体的质量和分布的方法。 由具有用于喷射探针溶液的喷射部分的探针载体制造的探针载体，每个探针溶液包含可与靶物质特异性结合的探针，用于将探针溶液施加在载体上，以及存储相互不同的多个探针罐 用于提供喷射部分的探针溶液。 每个探针槽都标有条形码。 标签条码由条形码阅读器读取。 根据读取的条形码，识别存储在探针罐中的探针溶液。 另一方面，探针箱安装在喷射部上。

公开(公告)号：US5725959A

公开(公告)日：1998-03-10

申请号：US754475

申请日：1996-11-22

申请人： Junji Terada ,  Makoto Kameyama ,  Junichi Sakamoto

发明人： Junji Terada ,  Makoto Kameyama ,  Junichi Sakamoto

IPC分类号： G02B1/11 ,  B32B9/04

CPC分类号： G02B1/115 ,  Y10T428/264 ,  Y10T428/31667

摘要： An antireflection film is procided on a plastic optical element as follows. An undercoat composed principally of unsaturated silicon exide SiO.sub.x (2>x>1) with a thickness within a range of 200 to 300 nm is formed on the optical element. A multi-layered film of a repeating structure is formed on the undercoat. The multi-layerd film has antireflective characteristics. The undercoat has a refractive index within a range of 1.49 to 1.59. The multi-layered film is composed of alternate lamination of a layer of a material which has a high refractive index and which is composed principally of TiO.sub.2, ZrO.sub.2 or a mixture thereof, and a layer of a material which has a low refractive index and which is composed principally of SiO.sub.x (2.gtoreq.x.gtoreq.1).

摘要翻译： 如下在塑料光学元件上进行防反射膜的制作。 在光学元件上形成厚度在200〜300nm范围内的主要由不饱和硅离子SiO x（2> x> 1）组成的底涂层。 在底涂层上形成重复结构的多层膜。 多层膜具有抗反射特性。 底涂层的折射率在1.49〜1.59的范围内。 多层膜由具有高折射率且主要由TiO 2，ZrO 2或其混合物组成的材料层的交替叠层和具有低折射率的材料层组成，并且其中 主要由SiOx（2> / = x> / = 1）组成。

公开(公告)号：US5578536A

公开(公告)日：1996-11-26

申请号：US428800

申请日：1995-04-24

申请人： Makoto Kameyama ,  Noboru Sugahara ,  Mitsuharu Sawamura ,  Junji Terada ,  Junichi Sakamoto

发明人： Makoto Kameyama ,  Noboru Sugahara ,  Mitsuharu Sawamura ,  Junji Terada ,  Junichi Sakamoto

IPC分类号： C23C14/08 ,  C23C14/24 ,  G02B1/10 ,  G02B1/115 ,  G02B5/28 ,  C04B35/46 ,  C04B35/48

CPC分类号： G02B5/285 ,  G02B1/10

摘要： An evaporation material is employed to form an optical thin film which is adapted to be formed on an optical element such as a lens or the like. The evaporation material is provided such that zirconium oxide (ZrO.sub.2) is mixed with a titanium oxide (TiO.sub.A) having a molar ratio A(O/Ti) of oxygen to titanium in a range of 1.0 to 1.75 so that the mixture assumes a molar ratio (Ti/Zr) of titanium to zirconium in a range of 1.0 to 4.0. The mixture is sintered or fused and solidified.

摘要翻译： 采用蒸发材料形成适于形成在诸如透镜等的光学元件上的光学薄膜。 提供蒸发材料，使得氧化锆（ZrO 2）与氧摩尔比A（O / Ti）至钛的氧化钛（TiOA）与1.0至1.75的范围内混合，使得混合物呈现摩尔比 （Ti / Zr）为1.0〜4.0的钛。 混合物烧结或熔融固化。

公开(公告)号：US4890378A

公开(公告)日：1990-01-02

申请号：US235824

申请日：1988-08-19

申请人： Takashi Suzuki ,  Toshio Yamanaka ,  Hiroyuki Suzuki ,  Tsuyoshi Orikasa ,  Takeshi Sawada ,  Makoto Kameyama ,  Kiyozumi Niizuma

发明人： Takashi Suzuki ,  Toshio Yamanaka ,  Hiroyuki Suzuki ,  Tsuyoshi Orikasa ,  Takeshi Sawada ,  Makoto Kameyama ,  Kiyozumi Niizuma

IPC分类号： G11B5/127 ,  G11B5/187 ,  G11B5/42

CPC分类号： G11B5/1878 ,  G11B5/127 ,  Y10T29/49043 ,  Y10T29/49057 ,  Y10T29/49067

摘要： A magnetic head in which a first magnetic film made of a material of high saturation magnetic flux density is deposited on the surface of a block made of a high permeability material and which contains a groove for winding. A nonmagnetic film made of a nonmagnetic material and serving as a magnetic gap is formed on the first magnetic film; and a second magnetic film made of a material of high saturation magnetic flux density is further formed on the nonmagnetic film. A reinforcing block is arranged on the second magnetic film and has a nonmagnetic material portion exposed to a slide surface of a recording medium. The high permeability material block, the first magnetic film and the second magnetic film together constitute a magnetic core, and the second magnetic film is bonded with the reinforcing block.

摘要翻译： 一种磁头，其中由高饱和磁通密度材料制成的第一磁性膜沉积在由高磁导率材料制成并且包含用于卷绕的凹槽的块的表面上。 在第一磁性膜上形成由非磁性材料制成并用作磁隙的非磁性膜; 并且在非磁性膜上进一步形成由高饱和磁通密度的材料制成的第二磁性膜。 加强块布置在第二磁性膜上，并且具有暴露于记录介质的滑动表面的非磁性材料部分。 高磁导率材料块，第一磁性膜和第二磁性膜一起构成磁芯，第二磁性膜与加强块结合。