专利检索 ap:("Mark Eshoo" OR "Christopher Crowder" OR "John Picuri" OR "Neill White" OR "Megan A. Rounds") AND inv:"Neill White" 第 1 页

1.

发明申请
TARGETED GENOME AMPLIFICATION METHODS 审中-公开
标题翻译：目标基因扩增方法

公开(公告)号：US20120100549A1

公开(公告)日：2012-04-26

申请号：US13250173

申请日：2011-09-30

申请人： Mark Eshoo , Christopher Crowder , John Picuri , Neill White , Megan A. Rounds

发明人： Mark Eshoo , Christopher Crowder , John Picuri , Neill White , Megan A. Rounds

IPC分类号： C12Q1/68

CPC分类号： C12Q1/686 , C12Q2531/119 , C12Q2537/159

摘要： The methods disclosed herein relate to methods and compositions for amplifying nucleic acid sequences, more specifically, from nucleic acid sequences of pathogens by targeted genome amplification. In certain embodiments, multiple primer pairs are employed that flank a target region and polymerization is conducted with a strand displacing enzyme.

摘要翻译： 本文公开的方法涉及用于通过靶向基因组扩增来更好地从核酸序列扩增核酸序列的方法和组合物。在某些实施方案中，使用在靶区域侧面的多个引物对，并且用链置换酶进行聚合。

2.

发明申请
Methods for rapid forensic analysis of mitochondrial DNA 审中-公开
标题翻译：线粒体DNA快速法医分析方法

公开(公告)号：US20050266411A1

公开(公告)日：2005-12-01

申请号：US10853660

申请日：2004-05-25

申请人： Steven Hofstadler , Thomas Hall , David Ecker , Lawrence Blyn , Mark Eshoo , Vivek Samant , Neill White

发明人： Steven Hofstadler , Thomas Hall , David Ecker , Lawrence Blyn , Mark Eshoo , Vivek Samant , Neill White

IPC分类号： C12Q1/68 , G01N27/447 , G01N33/48 , G01N33/50 , G06F19/00

CPC分类号： G01N27/62 , C12Q1/683 , C12Q1/6846 , G01N27/447 , G16B50/00 , C12Q2565/627 , C12Q2521/301

摘要： The present invention provides methods for rapid forensic analysis of mitochondrial DNA by amplification of a segment of mitochondrial DNA containing restriction sites, digesting the mitochondrial DNA segments with restriction enzymes, determining the molecular masses of the restriction fragments and comparing the molecular masses with the molecular masses of theoretical restriction digests of known mitochondrial DNA sequences stored in a database.

摘要翻译： 本发明提供了通过扩增含有限制性位点的线粒体DNA片段，用限制酶消化线粒体DNA片段，确定限制性片段的分子量并将分子量与分子量进行比较的线粒体DNA的快速法医分析方法已知线粒体DNA序列的理论限制性消化存储在数据库中。

3.

发明授权
Methods for rapid forensic analysis of mitochondrial DNA 失效
标题翻译：线粒体DNA快速法医分析方法

公开(公告)号：US08407010B2

公开(公告)日：2013-03-26

申请号：US12049949

申请日：2008-03-17

申请人： Steven A. Hofstadler , Thomas A. Hall , David J. Ecker , Lawrence B. Blyn , Mark W. Eshoo , Vivek Samant , Neill White

发明人： Steven A. Hofstadler , Thomas A. Hall , David J. Ecker , Lawrence B. Blyn , Mark W. Eshoo , Vivek Samant , Neill White

IPC分类号： G06F7/00

CPC分类号： G01N27/62 , C12Q1/683 , C12Q1/6846 , G01N27/447 , G06F19/28 , C12Q2565/627 , C12Q2521/301

摘要： The present invention provides methods for rapid forensic analysis of mitochondrial DNA by amplification of a segment of mitochondrial DNA containing restriction sites, digesting the mitochondrial DNA segments with restriction enzymes, determining the molecular masses of the restriction fragments and comparing the molecular masses with the molecular masses of theoretical restriction digests of known mitochondrial DNA sequences stored in a database.

摘要翻译： 本发明提供了通过扩增含有限制性位点的线粒体DNA片段，用限制酶消化线粒体DNA片段，确定限制性片段的分子量并将分子量与分子量进行比较的线粒体DNA的快速法医分析方法已知线粒体DNA序列的理论限制性消化存储在数据库中。

4.

发明申请
Methods for identifying bioagents 有权
标题翻译：识别生物标签的方法

公开(公告)号：US20090239224A1

公开(公告)日：2009-09-24

申请号：US12326800

申请日：2008-12-02

申请人： David J. Ecker , Richard H. Griffey , Rangarajan Sampath , Steven A. Hofstadler , John McNeil , Stanley T. Crooke , Lawrence B. Blyn , Thomas A. Hall , Yun Jiang , James C. Hannis , Neill White , Vivek Samant , Mark W. Eshoo , Jared J. Drader

发明人： David J. Ecker , Richard H. Griffey , Rangarajan Sampath , Steven A. Hofstadler , John McNeil , Stanley T. Crooke , Lawrence B. Blyn , Thomas A. Hall , Yun Jiang , James C. Hannis , Neill White , Vivek Samant , Mark W. Eshoo , Jared J. Drader

IPC分类号： C12Q1/68

CPC分类号： C12Q1/686 , C12Q1/6806 , C12Q1/6844 , C12Q1/6858 , C12Q1/6872 , C12Q1/6888 , C12Q1/689 , C12Q2600/156 , G01N2333/28 , G01N2333/32 , G01N2333/35 , G01N2333/36 , C12Q2563/167 , C12Q2545/101 , C12Q2531/113 , C12Q2565/627 , C12Q2545/113

摘要： The present invention provides methods for rapid forensic analysis of mitochondrial DNA and methods for characterizing heteroplasmy of mitochondrial DNA, which can be used to assess the progression of mitochondrial diseases.

摘要翻译： 本发明提供线粒体DNA的快速法医分析方法和线粒体DNA异质性表征的方法，可用于评估线粒体疾病的进展。

5.

发明申请
Methods For Rapid Forensic Analysis Of Mitochondrial DNA 审中-公开

公开(公告)号：US20130337452A1

公开(公告)日：2013-12-19

申请号：US13850683

申请日：2013-03-26

申请人： Steven A. Hofstadler , Thomas A. Hall , David J. Ecker , Lawrence B. Blyn , Mark W. Eshoo , Vivek Samant , Neill White

发明人： Steven A. Hofstadler , Thomas A. Hall , David J. Ecker , Lawrence B. Blyn , Mark W. Eshoo , Vivek Samant , Neill White

IPC分类号： G01N27/62

CPC分类号： G01N27/62 , C12Q1/683 , C12Q1/6846 , G01N27/447 , G16B50/00 , C12Q2565/627 , C12Q2521/301

摘要： The present invention provides methods for rapid forensic analysis of mitochondrial DNA by amplification of a segment of mitochondrial DNA containing restriction sites, digesting the mitochondrial DNA segments with restriction enzymes, determining the molecular masses of the restriction fragments and comparing the molecular masses with the molecular masses of theoretical restriction digests of known mitochondrial DNA sequences stored in a database.

6.

发明申请
Methods For Rapid Forensic Analysis Of Mitochondrial DNA 失效
标题翻译：线粒体DNA快速法医分析方法

公开(公告)号：US20090125245A1

公开(公告)日：2009-05-14

申请号：US12049949

申请日：2008-03-17

申请人： Steven A. Hofstadler , Thomas A. Hall , David J. Ecker , Lawrence B. Blyn , Mark W. Eshoo , Vivek Samant , Neill White

发明人： Steven A. Hofstadler , Thomas A. Hall , David J. Ecker , Lawrence B. Blyn , Mark W. Eshoo , Vivek Samant , Neill White

IPC分类号： C12Q1/68 , G01N33/48 , C07H21/04

CPC分类号： G01N27/62 , C12Q1/683 , C12Q1/6846 , G01N27/447 , G06F19/28 , C12Q2565/627 , C12Q2521/301

摘要： The present invention provides methods for rapid forensic analysis of mitochondrial DNA by amplification of a segment of mitochondrial DNA containing restriction sites, digesting the mitochondrial DNA segments with restriction enzymes, determining the molecular masses of the restriction fragments and comparing the molecular masses with the molecular masses of theoretical restriction digests of known mitochondrial DNA sequences stored in a database.

摘要翻译： 本发明提供了通过扩增含有限制性位点的线粒体DNA片段，用限制酶消化线粒体DNA片段，确定限制性片段的分子量并将分子量与分子量进行比较的线粒体DNA的快速法医分析方法已知线粒体DNA序列的理论限制性消化存储在数据库中。