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205 条记录 (耗时 0.039 秒)

    Adsorbent, method for production thereof, and method for use thereof
    1.
    发明授权
    Adsorbent, method for production thereof, and method for use thereof 失效
    吸附剂，其制造方法及其使用方法

    公开(公告)号：US5132402A

    公开(公告)日：1992-07-21

    申请号：US265540

    申请日：1988-11-01

    申请人： Masao Tanihara ,  Kiichiro Oka ,  Hideaki Yamada ,  Akira Kobayashi ,  Toshihide Nakashima ,  Yoshiaki Omura ,  Koichi Takakura

    发明人： Masao Tanihara ,  Kiichiro Oka ,  Hideaki Yamada ,  Akira Kobayashi ,  Toshihide Nakashima ,  Yoshiaki Omura ,  Koichi Takakura

    IPC分类号： A61M1/36 ,  C07K14/705

    CPC分类号： C07K14/705 ,  A61M1/3679

    摘要： There is disclosed an adsorbent, comprising a carrier on which is immobilized a peptide possessing an ability to bind to the human antibody to the nicotinic acetylcholine receptor and represented by the formula:H--X--A--Y--Zwherein A stands for a peptide residue, one of X and Y stands for a single bond, an amino acid residue selected from the class consisting of Asp, Glu, Lys and a divalent group represented by the formula, ##STR1## (wherein n stands for an integer in the range of 1 to 17), or a peptide residue formed by peptide linkage of two to ten amino acid residues of at least one species selected from the class mentioned above and the other of X and Y stands for an amino acid residue selected from the class consisting of Asp, Glu, Lys and a divalent group represented by the formula, ##STR2## (wherein n stands for an integer in the range of 1 to 17), or a peptide residue formed by peptide linkage of two to ten amino acid residues of at least one species selected from the class mentioned above and Z stands for a hydroxyl group or an amino group. A method for the production of the adsorbent and a method for the use of the adsorbent are also disclosed.

    摘要翻译： 公开了一种吸附剂，其包含载体，其上固定有具有与烟碱乙酰胆碱受体的人抗体结合的能力并由下式表示的肽：HXAYZ其中A代表肽残基，X和Y之一 对于单键，选自Asp，Glu，Lys和由下式表示的二价基团的氨基酸残基（其中n表示1至17的整数）或 通过选自上述类别的至少一种的2至10个氨基酸残基和X和Y中的另一个的肽键形成的肽残基代表选自Asp，Glu，Lys和 由下式表示的二价基团（其中n表示1〜17的整数），或由选自所述类别的至少一种的2〜10个氨基酸残基通过肽键形成的肽残基 提到 Z代表羟基或氨基。 还公开了制备吸附剂的方法和吸附剂的使用方法。

    Peptide
    2.
    发明授权
    Peptide 失效
    肽

    公开(公告)号：US4889917A

    公开(公告)日：1989-12-26

    申请号：US265550

    申请日：1988-11-01

    申请人： Masao Tanihara ,  Kiichiro Oka ,  Hideaki Yamada ,  Akira Kobayashi ,  Toshihide Nakashima ,  Yoshiaki Omura ,  Koichi Takakura

    发明人： Masao Tanihara ,  Kiichiro Oka ,  Hideaki Yamada ,  Akira Kobayashi ,  Toshihide Nakashima ,  Yoshiaki Omura ,  Koichi Takakura

    IPC分类号： A61K38/00 ,  A61M1/36 ,  A61P43/00 ,  C07K7/08 ,  C07K14/00 ,  C07K14/435 ,  C07K14/705 ,  G01N33/564 ,  G01N33/566

    CPC分类号： C07K14/705 ,  A61M1/3679 ,  Y02P20/55

    摘要： A peptide is disclosed which is represented by the formula:H-X-Gly-Trp-Lys-His-Trp-Val-Tyr-Tyr-Thr-Cys-Cys-Pro-Asp-Thr-Pro-Tyr-Leu-Asp-Y -Zwherein one of X and Y stands for a single bond, an amino acid residue selected from the class consisting of Asp, Glu, Lys and a divalent group represented by the formula, ##STR1## (wherein n stands for an integer in the range of 1 to 17), or a peptide residue formed by peptide linkage of two to ten amino acid residues of at least one species selected from the class mentioned above, the other of X and Y stands for an amino acid residue selected from the class consisting of Asp, Glu, Lys and a divalent group represented by the formula, ##STR2## (wherein n stands for an integer in the range of 1 to 17), or a peptide residue formed by peptide linkage of two to ten amino acid residues of at least one species selected from the class mentioned above and Z stands for a hydroxyl group or an amino group, and two cysteinyl mercapto groups in the Cys-Cys moiety may be interlinked to each other to form a disulfide bond.

    摘要翻译： 公开了由下式表示的肽：HX-Gly-Trp-Lys-His-Trp-Val-Tyr-Tyr-Thr-Cys-Cys-Pro-Asp-Thr-Pro-Tyr-Le-Asp- Y -Z其中X和Y中的一个代表单键，选自Asp，Glu，Lys和由下式表示的二价基团的氨基酸残基：其中n表示 1至17的范围）或通过选自上述类别的至少一种的2至10个氨基酸残基的肽键形成的肽残基，X和Y中的另一个表示选自以下的氨基酸残基： 由Asp，Glu，Lys和由式表示的二价基团，其中n表示1〜17的整数，或由2〜10个氨基酸的肽键形成的肽残基 选自上述类别中的至少一种的残基和Z表示羟基或氨基，并且Cys-Cys moie中的两个半胱氨酰巯基 ty可以彼此互连以形成二硫键。

    Vibration damping bushing and manufacturing method thereof
    3.
    发明授权
    Vibration damping bushing and manufacturing method thereof 有权
    振动阻尼衬套及其制造方法

    公开(公告)号：US08979082B2

    公开(公告)日：2015-03-17

    申请号：US13491271

    申请日：2012-06-07

    申请人： Takashi Makino ,  Chiharu Tanaka ,  Akira Kobayashi

    发明人： Takashi Makino ,  Chiharu Tanaka ,  Akira Kobayashi

    IPC分类号： F16F15/08 ,  F16F1/38 ,  B60G7/00

    CPC分类号： F16F1/3828 ,  B60G7/001 ,  B60G2204/41 ,  F16F1/3863 ,  Y10T29/49844

    摘要： A vibration damping bushing including: an inner axial member; an outer cylindrical member through which the inner axial member is inserted; a main rubber elastic body elastically connecting the two members; and a stopper member that is fitted onto the inner axial member as a component of a first stopper mechanism that limits relative displacement of the inner axial member against the outer cylindrical member to one side in an axial direction. The inner axial member is formed with a latching depression that opens toward an outer periphery thereof, and the stopper member is provided with a latching piece that protrudes outward in the axial direction. The latching piece is engaged with the latching depression so as to provide a slipping out prevention mechanism for preventing the stopper member from slipping out from the inner axial member.

    摘要翻译： 一种减震衬套，包括：内轴向构件; 内部轴向构件插入其中的外部圆柱形构件; 弹性地连接两个构件的主橡胶弹性体; 以及止动构件，其配合在作为第一止动机构的部件的内轴构件上，该第一止动机构限制内轴向构件相对于外圆筒构件相对于轴向一侧的相对位移。 内轴向构件形成有朝向其外周开口的卡止凹部，止动构件设置有沿轴向向外突出的卡定片。 闩锁件与闩锁凹部接合，以提供防止止动构件从内轴向构件滑出的防滑机构。

    Content distribution system, content distribution method and program
    4.
    发明授权
    Content distribution system, content distribution method and program 有权
    内容分发系统，内容分发方式和程序

    公开(公告)号：US08484697B2

    公开(公告)日：2013-07-09

    申请号：US12523854

    申请日：2007-12-26

    申请人： Junichi Sato ,  Akira Kobayashi ,  Katsuhiro Ochiai ,  Motonobu Kimura ,  Kaname Naito ,  Shuhei Miura

    发明人： Junichi Sato ,  Akira Kobayashi ,  Katsuhiro Ochiai ,  Motonobu Kimura ,  Kaname Naito ,  Shuhei Miura

    IPC分类号： G06F7/04 ,  G06F17/30 ,  G06F15/173

    CPC分类号： H04L63/168 ,  G06F21/10 ,  G06F21/33 ,  H04L63/0838

    摘要： A content distribution system. A distribution management and unauthorized operation management device generates a one-time URL by using URL of content information specified by a user terminal and transmits the one-time URL and bandwidth information concerning the content information to the user terminal. A session control server extracts the one-time URL from a session control message transmitted from the user terminal, transmits it to the distribution management and unauthorized operation management device, and establishes a session between the content distribution server and the user terminal according to an authentication result performed by using the one-time URL transmitted from the distribution management and unauthorized operation management device and a correlation result obtained by correlating the bandwidth information contained in the session control message transmitted from the user terminal with the bandwidth information transmitted together with the authentication result from the distribution management and unauthorized operation management device.

    摘要翻译： 内容分发系统。 分发管理和未经授权的操作管理设备通过使用由用户终端指定的内容信息的URL来生成一次性URL，并将一次性URL和关于内容信息的带宽信息发送给用户终端。 会话控制服务器从用户终端发送的会话控制消息中提取一次性URL，将其发送到分发管理和未经授权的操作管理设备，并根据认证建立内容分发服务器与用户终端之间的会话 通过使用从分发管理和未经授权的操作管理装置发送的一次性URL执行的结果以及将从用户终端发送的会话控制消息中包含的带宽信息与认证结果一起发送的带宽信息相关联的相关结果 从配送管理和未经授权的运营管理设备。

    Rail manufacturing method
    6.
    发明授权
    Rail manufacturing method 有权
    轨道制造方法

    公开(公告)号：US07828917B2

    公开(公告)日：2010-11-09

    申请号：US10585472

    申请日：2005-01-07

    申请人： Noriaki Onodera ,  Takuya Satoh ,  Masaharu Ueda ,  Kazuo Fujita ,  Akira Kobayashi

    发明人： Noriaki Onodera ,  Takuya Satoh ,  Masaharu Ueda ,  Kazuo Fujita ,  Akira Kobayashi

    IPC分类号： C21D9/04 ,  C21D9/06

    CPC分类号： C21D9/06 ,  B21B1/085 ,  B21B2045/0254 ,  C21D1/84 ,  C21D9/04

    摘要： A rail manufacturing method is provided, in which a billet is hot-rolled into a rail form and the rail is cooled to ambient temperature. The foot part of the rail can be mechanically restrained to improve the straightness of the rail during at least the period of cooling where the surface temperature is between 800° C. and 400° C. In the subsequent cooling process, at least while the surface temperature of the foot of the rail is between 400° C. and 250° C., the rail is kept in an upright state, and cooled naturally without using insulation or accelerated cooling.

    摘要翻译： 提供了一种轨道制造方法，其中坯料被热轧成轨道形式并且轨道被冷却到环境温度。 轨道的脚部可以被机械地约束，以至少在表面温度在800℃和400℃之间的冷却期间提高轨道的平直度。在随后的冷却过程中，至少在表面 导轨脚的温度在400°C到250°C之间，轨道保持直立状态，并自然冷却而不使用绝缘或加速冷却。

    STEM CELL SEPARATING MATERIAL AND METHOD OF SEPARATION
    9.
    发明申请
    STEM CELL SEPARATING MATERIAL AND METHOD OF SEPARATION 有权
    干细胞分离材料和分离方法

    公开(公告)号：US20090142835A1

    公开(公告)日：2009-06-04

    申请号：US12091029

    申请日：2006-10-20

    申请人： Akira Kobayashi ,  Kazuaki Yamamoto ,  Shinya Yoshida ,  Hideo Niwa ,  Naohiro Imai ,  Hirokazu Kurata ,  Yoshiaki Miyamoto

    发明人： Akira Kobayashi ,  Kazuaki Yamamoto ,  Shinya Yoshida ,  Hideo Niwa ,  Naohiro Imai ,  Hirokazu Kurata ,  Yoshiaki Miyamoto

    IPC分类号： C12N5/06

    CPC分类号： C12N5/0607 ,  B01D39/1623 ,  B01D39/1692 ,  B01D2239/0414 ,  C12M33/14 ,  C12M47/02

    摘要： The present invention has its object to provide a material for separating stem cell and a filter for separating stem cell, each is capable of selectively separating and recovering, in a simple and easy manner, stem cells from body fluids or biological tissue-derived treated fluids, a method for separating and recovering stem cells, and stem cells obtained by such method. The present invention is a material for separating stem cell which has a density K of 1.0×104≦K≦1.0×106 and a fiber diameter of 3 to 40 μm; a filter for separating stem cell which comprises the material for separating stem cell as packed in a container having a fluid inlet port and a fluid outlet port; a method of separating and recovering stem cells which comprises using the material for separating stem cell or the filter for separating stem cell; and a method of producing a multipotent cell fraction.

    摘要翻译： 本发明的目的是提供用于分离干细胞的材料和用于分离干细胞的过滤器，每种能够以简单和容易的方式从体液或生物组织衍生的处理液中分离和回收干细胞 ，分离和回收干细胞的方法和通过这种方法获得的干细胞。 本发明是一种用于分离密度K为1.0×104 <= K <= 1.0×10 6，纤维直径为3〜40μm的干细胞的材料。 用于分离干细胞的过滤器，其包括用于分离干细胞的材料，所述干细胞包装在具有流体入口和流体出口的容器中; 分离和回收干细胞的方法，其包括使用用于分离干细胞的材料或用于分离干细胞的过滤器; 以及多能细胞部分的制造方法。