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    4.sup.G -alpha-D-glucopyranosyl rutin, and its preparation and uses
    5.
    发明授权
    4.sup.G -alpha-D-glucopyranosyl rutin, and its preparation and uses 失效
    4G-α-D-吡喃葡萄糖芦丁及其制备和用途

    公开(公告)号：US5171573A

    公开(公告)日：1992-12-15

    申请号：US745634

    申请日：1991-08-15

    申请人： Yukio Suzuki ,  Kei Suzuki ,  Masaru Yoneyama ,  Toshio Miyake

    发明人： Yukio Suzuki ,  Kei Suzuki ,  Masaru Yoneyama ,  Toshio Miyake

    IPC分类号： A23L3/3472 ,  A23L3/3544 ,  A61K8/49 ,  A61K8/60 ,  A61Q1/02 ,  A61Q5/02 ,  A61Q11/00 ,  A61Q17/04 ,  A61Q19/00 ,  A61Q19/02 ,  C07H17/07

    CPC分类号： C07H17/07 ,  A23L3/3472 ,  A23L3/3544 ,  A61K8/602 ,  A61Q1/02 ,  A61Q1/06 ,  A61Q17/04 ,  A61Q19/00 ,  A61Q5/02 ,  A61K2800/522 ,  A61Q11/00 ,  A61Q19/02 ,  Y10S514/827 ,  Y10S514/844 ,  Y10S514/845 ,  Y10S514/846 ,  Y10S514/847 ,  Y10S514/848

    摘要： A novel glycoside, 4.sup.G -alpha-D-glucopyranosyl rutin, is formed by a saccharide-transferring enzyme and glucoamylase in a solution which contains rutin together with glucoamylase. The 4.sup.G -alpha-D-glucopyranosyl rutin formed in such a solution is purified with a synthetic macroreticular resin, and crystallization in an organic solvent yields a complex crystal with the organic solvent. 4.sup.G -Alpha-D-glucopyranosyl rutin exhibits the same molecular absorption coefficient as intact rutin, and is readily water-soluble, substantially tasteless and odorless, and readily hydrolyzable in vivo to exhibit physiological activities inherent to rutin. These render 4.sup.G -alpha-D-glucopyranosyl rutin very useful as a highly-safe, natural yellow coloring agent, antioxidant, stabilizer, quality-improving agent, preventive, remedy, uv-absorbent and deterioration-preventing agent in foods, beverages, tobaccos, cigarets, feeds, pet foods, pharmaceuticals, cosmetics and plastics.

    摘要翻译： 通过糖转移酶和葡糖淀粉酶在含有芦丁与葡糖淀粉酶的溶液中形成新的糖苷，4G-α-D-吡喃葡萄糖苷芦丁。 在这种溶液中形成的4G-α-D-吡喃葡糖基芦丁用合成的大网状树脂进行纯化，在有机溶剂中结晶，得到有机溶剂的复合结晶。 4G-α-D-吡喃葡萄糖芦丁显示出与完整芦丁相同的分子吸收系数，易溶于水，基本上无味无味，并且在体内易于水解，表现出芦丁固有的生理活性。 这些使4G-α-D-吡喃葡萄糖芦荟非常适用于食品，饮料，烟草中高度安全，天然的黄色着色剂，抗氧化剂，稳定剂，质量改进剂，预防，补救，紫外线吸收剂和防腐剂 ，烟草，饲料，宠物食品，药品，化妆品和塑料。

    .alpha.-glycosyl quercetin, and its preparation and uses
    8.
    发明授权
    .alpha.-glycosyl quercetin, and its preparation and uses 失效
    α-糖基槲皮素及其制备和用途

    公开(公告)号：US5565435A

    公开(公告)日：1996-10-15

    申请号：US390277

    申请日：1995-02-15

    申请人： Masaru Yoneyama ,  Satoshi Iritani ,  Toshio Miyake

    发明人： Masaru Yoneyama ,  Satoshi Iritani ,  Toshio Miyake

    IPC分类号： A23K1/16 ,  A23L1/275 ,  A61K8/00 ,  A61K8/49 ,  A61K31/70 ,  A61K31/7042 ,  A61K31/7048 ,  A61P17/00 ,  A61P17/16 ,  A61Q17/04 ,  A61Q19/00 ,  A61Q19/02 ,  C07H17/07 ,  C09K3/00 ,  C09K15/08 ,  C12P19/60 ,  C07H15/24 ,  C12P19/14 ,  C12P19/18

    CPC分类号： A61Q19/00 ,  A61K8/602 ,  A61Q17/04 ,  A61Q19/02 ,  C07H17/07

    摘要： A novel .alpha.-glycosyl quercetin, wherein at least equimolar D-glucose residues are attached to quercetin via the .alpha.-bond, has a satisfactory water-solubility, light tolerance and stability, and exerts the inherent activity of quercetin in vivo. The .alpha.-glycosyl quercetin is prepared by a process comprising subjecting a solution containing quercetin and an .alpha.-glucosyl saccharide to the action of a saccharide-transferring enzyme to form an .alpha.-glycosyl quercetin, and recoverying the resultant .alpha.-glycosyl quercetin. The .alpha.-glycosyl quercetin can be advantageously used in combination with other materials in food products, cosmetic compositions and pharmaceutical compositions as a highly-safe and natural vitamin P-enriched agent, yellow-color-imparting agent, antioxidant, deodorant, stabilizer, quality-improving agent, antiseptic, prophylactic agent, therapeutic agent and ultraviolet-absorbing agent.

    摘要翻译： 一种新型α-糖基槲皮素，其中至少等摩尔D-葡萄糖残基通过α键与槲皮素连接，具有令人满意的水溶性，光耐受性和稳定性，并且在体内发挥槲皮素的固有活性。 α-糖基槲皮素通过包括使含有槲皮素和α-葡糖基糖的溶液进行糖转移酶的作用以形成α-糖基槲皮素并回收所得的α-糖基槲皮素的方法制备。 α-糖基槲皮素可有利地与食品，化妆品组合物和药物组合物中的其它材料组合使用，作为高度安全和天然的维生素P富集剂，黄色赋予剂，抗氧化剂，除臭剂，稳定剂，质量 改善剂，防腐剂，预防剂，治疗剂和紫外线吸收剂。