公开(公告)号：US6142333A

公开(公告)日：2000-11-07

申请号：US865300

申请日：1997-05-29

申请人： Masayoshi Sasamoto ,  Seiichi Sato ,  Takashi Takeuchi ,  Shogo Sasaoka ,  Takehiro Terai

发明人： Masayoshi Sasamoto ,  Seiichi Sato ,  Takashi Takeuchi ,  Shogo Sasaoka ,  Takehiro Terai

IPC分类号： B60R7/04 ,  E05D15/50 ,  B65D43/26

CPC分类号： B60R7/04 ,  E05B83/32 ,  E05D15/502 ,  E05Y2900/538

摘要： An opening and closing apparatus for a lid including a box body, a lid openable and closable in a first direction and a second direction relative to the box body, a movable member movable to a first position for opening the lid in the first direction, a second position for opening the lid in the second direction, and a closing position for closing the lid, first and second operating buttons integrally coupled to the opposite end portions of the movable member, a first biasing member for normally biasing the movable member to the closing position, and a holding member for holding the movable member in the first position against the biasing force of the first biasing member when the first operating button is pressed and the movable member is moved to the first position, and holding the movable member in the second position against the biasing force of the first biasing member when the second operating button is pressed and the movable member is moved to the second position, the holding member being disposed near the edge of the lid extending parallel to the first and second directions, the movable member being disposed off the center of the lid and near the holding member.

摘要翻译： 一种用于盖子的开闭装置，包括盒体，在第一方向可开启和关闭的盖子，相对于盒体的第二方向可移动的第一位置，用于沿第一方向打开盖子的可移动部件， 用于在第二方向上打开盖的第二位置和用于关闭盖的关闭位置，与可动构件的相对端部一体地联接的第一和第二操作按钮，用于将可动构件正常地偏压到闭合位置的第一偏压构件 位置，以及保持构件，当第一操作按钮被按压并且可动构件移动到第一位置时，抵抗第一施力构件的作用力将可动构件保持在第一位置，并且将可动构件保持在第二位置 当所述第二操作按钮被按压并且所述可移动部件移动到所述第二位置时，抵抗所述第一偏压部件的偏置力的位置，所述保持部 灰烬设置在平行于第一和第二方向延伸的盖的边缘附近，可动构件设置在盖的中心附近并且靠近保持构件。

公开(公告)号：US08673168B2

公开(公告)日：2014-03-18

申请号：US13821603

申请日：2011-09-09

申请人： Seiichi Sato ,  Mari Miyano ,  Shigeki Endo ,  Osamu Shiino ,  Shingo Ono ,  Masato Yoshikawa

发明人： Seiichi Sato ,  Mari Miyano ,  Shigeki Endo ,  Osamu Shiino ,  Shingo Ono ,  Masato Yoshikawa

IPC分类号： B44C1/22 ,  C03C15/00 ,  C03C25/68 ,  C23F1/00

CPC分类号： B44C1/227 ,  C01B33/025 ,  C01B33/037

摘要： An object and project of the present invention is to provide a method for producing silicon fine particles and a method for controlling a particle diameter of silicon fine particles which enable efficient production of silicon fine particles having a uniform particle diameter. A the characteristics of the present invention is producing silicon fine particles having a smaller particle diameter than silicon particles and controlling a particle diameter of silicon fine particles by immersing the silicon particles into an etching solution and irradiating the silicon particles immersed in the etching solution with light having a larger energy than a band gap energy of the silicon particles.

摘要翻译： 本发明的目的和项目是提供一种硅微粒的制造方法和控制硅微粒的粒径的方法，能够有效地制造具有均匀粒径的硅微粒。 本发明的特征在于制造粒径小于硅粒子的硅微粒，通过将硅粒子浸渍在蚀刻溶液中并照射浸渍在蚀刻溶液中的硅粒子来控制硅微粒的粒径 具有比硅颗粒的带隙能量更大的能量。

公开(公告)号：US08575153B2

公开(公告)日：2013-11-05

申请号：US13131561

申请日：2009-11-27

申请人： Takahiro Kitamura ,  Hajime Yamada ,  Shunji Takemura ,  Masanori Ashikawa ,  Tetsuya Ishikawa ,  Yoshiharu Miyake ,  Akiyasu Kouketsu ,  Seiichi Sato ,  Hiroyuki Ishiwata ,  Yuichiro Tabunoki ,  Manabu Shibasaki ,  Takatoshi Ozawa ,  Ryota Shigemi ,  Takeshi Doi ,  Masahiro Tamura

发明人： Takahiro Kitamura ,  Hajime Yamada ,  Shunji Takemura ,  Masanori Ashikawa ,  Tetsuya Ishikawa ,  Yoshiharu Miyake ,  Akiyasu Kouketsu ,  Seiichi Sato ,  Hiroyuki Ishiwata ,  Yuichiro Tabunoki ,  Manabu Shibasaki ,  Takatoshi Ozawa ,  Ryota Shigemi ,  Takeshi Doi ,  Masahiro Tamura

IPC分类号： A61K31/506 ,  C07D239/48

CPC分类号： C07D213/82 ,  C07D401/12 ,  C07D401/14 ,  C07D405/12 ,  C07D413/12 ,  C07D417/12

摘要： To provide a novel JAK3 inhibitor that is useful as a preventive and/or therapeutic agent for rejection and graft versus host disease (GvHD) in organ transplantation, rheumatoid arthritis, multiple sclerosis, systemic lupus erythematosus, Sjögren syndrome, Behcet's disease, type I diabetes mellitus, autoimmune thyroiditis, idiopathic thrombocytopenic purpura, ulcerative colitis, Crohn's disease, asthma, allergic rhinitis, atopic dermatitis, contact dermatitis, urticaria, eczema, psoriasis, allergic conjunctivitis, uveitis, cancer, leukemia and the like. The pyridine-3-carboxyamide derivative represented by the general formula (1): or its salt or a solvate thereof.

摘要翻译： 提供可用作器官移植，类风湿关节炎，多发性硬化症，系统性红斑狼疮，Sjögren综合征，Behcet氏病，I型糖尿病的排斥反应和宿主疾病（GvHD）的预防和/或治疗剂的新型JAK3抑制剂 过敏性甲状腺炎，特发性血小板减少性紫癜，溃疡性结肠炎，克罗恩病，哮喘，过敏性鼻炎，特应性皮炎，接触性皮炎，荨麻疹，湿疹，牛皮癣，过敏性结膜炎，葡萄膜炎，癌症，白血病等。 由通式（1）表示的吡啶-3-甲酰胺衍生物或其盐或其溶剂化物。

公开(公告)号：US20120034364A1

公开(公告)日：2012-02-09

申请号：US13249523

申请日：2011-09-30

申请人： FUMIE FUTAKI ,  Reiko Yasuda ,  Seiichi Sato ,  Takashi Miyaki ,  Naohiro Miyamura ,  Yuzuru Eto

发明人： FUMIE FUTAKI ,  Reiko Yasuda ,  Seiichi Sato ,  Takashi Miyaki ,  Naohiro Miyamura ,  Yuzuru Eto

IPC分类号： A23L1/227 ,  C07K5/072

CPC分类号： A23L27/22 ,  A23L27/21

摘要： The inventors of this invention have conducted the search for a variety of compounds which may possess a desired CaSR agonist activity to thus find out a substance capable of imparting a kokumi, which shows a more excellent kokumi-imparting effect, in particular, a kokumi-imparting effect of the initial taste-imparting type one, which is excellent in the stability and which can easily be produced at a low cost and the present invention thus provide a kokumi-imparting agent consisting of such a substance as well as a complex kokumi-imparting agent comprising the substance and other substances possessing the CaSR agonist activities in combination. More particularly, the present invention herein provides a kokumi-imparting agent consisting of γ-Glu-Abu (L-γ-glutamyl-L-2-amino-butyric acid) and a complex kokumi-imparting agent comprising the foregoing substance and another substance having a CaSR agonist activity, in combination.

摘要翻译： 本发明的发明人已经进行了可能具有所需CaSR激动剂活性的各种化合物的寻找，从而找出能够赋予kokumi的物质，这表现出更优异的赋粉效果，特别是kokumi- 赋予了稳定性优异且易于以低成本制造的初始味觉赋予型赋予效果，因此本发明提供了由这种物质组成的赋粉剂以及复合的kokumi- 包含该物质和具有CaSR激动剂活性的其它物质组合的赋形剂。 更具体地说，本发明提供由γ-Glu-Abu（L-γ-谷氨酰基-L-2-氨基 - 丁酸）和包含上述物质的复合kokumi赋予剂和另一种物质 具有CaSR激动剂活性。

公开(公告)号：US20120028983A1

公开(公告)日：2012-02-02

申请号：US13263023

申请日：2010-04-16

申请人： Toru Miura ,  Kazuhiro Onogi ,  Seiichi Sato ,  Junya Tagashira ,  Gen Watanabe ,  Ryohei Sekimoto ,  Rie Ishida ,  Hitomi Aoki ,  Tadaaki Ohgiya

发明人： Toru Miura ,  Kazuhiro Onogi ,  Seiichi Sato ,  Junya Tagashira ,  Gen Watanabe ,  Ryohei Sekimoto ,  Rie Ishida ,  Hitomi Aoki ,  Tadaaki Ohgiya

IPC分类号： A61K31/53 ,  C07D403/14 ,  C07D413/14 ,  C07D417/14 ,  A61P13/12 ,  A61P3/00 ,  A61P3/10 ,  A61P9/00 ,  A61P9/10 ,  A61P9/12 ,  C07D401/14 ,  A61K31/513

CPC分类号： C07D401/14 ,  C07D403/14 ,  C07D413/14 ,  C07D417/14

摘要： Disclosed is a compound which has both an angiotensin-II receptor antagonistic activity and a PPARγ activation activity and is useful as a prophylactic and/or therapeutic agent for hypertension, heart diseases, angina pectoris, cerebrovascular disorders, cerebral circulatory disorders, ischemic peripheral circulatory disorders, renal diseases, arteriosclerosis, inflammatory diseases, type-2 diabetes, diabetic complications, insulin resistance syndrome, syndrome X, metabolic syndrome and hyperinsulinemia. [In the formula, A represents a 5- to 10-membered heteroaryl group; R1 and R2 independently represent a C1-6 alkyl group; and each of R3 to R5 is absent or represents H, a halogen atom, OH, NO2, a halo-C1-6 alkyl group, a (substituted) C1-6 alkoxy group, a (substituted) C3-6 cycloalkyloxy group, or a 5- to 10-membered heteroaryl group.]

摘要翻译： 公开了具有血管紧张素-II受体拮抗作用和PPARγ活化活性的化合物，可用作高血压，心脏病，心绞痛，脑血管病，脑循环障碍，缺血性外周循环障碍的预防和/或治疗剂 肾脏疾病，动脉硬化，炎性疾病，2型糖尿病，糖尿病并发症，胰岛素抵抗综合征，X综合征，代谢综合征和高胰岛素血症。 [式中，A表示5至10元杂芳基; R1和R2独立地表示C1-6烷基; 并且R 3至R 5不存在或表示H，卤素原子，OH，NO 2，卤代C 1-6烷基，（取代的）C 1-6烷氧基，（取代的）C 3-6环烷氧基或 5至10元杂芳基。]

公开(公告)号：US07919203B2

公开(公告)日：2011-04-05

申请号：US11664699

申请日：2005-10-07

申请人： Kentaro Shibuya ,  Hiroshi Kosaka ,  Keishi Kousaka ,  Koichi Hasegawa ,  Seiichi Sato

发明人： Kentaro Shibuya ,  Hiroshi Kosaka ,  Keishi Kousaka ,  Koichi Hasegawa ,  Seiichi Sato

IPC分类号： H01M2/10

CPC分类号： H01M2/105

摘要： A battery box structure includes a battery module, a holding frame which holds the battery module, a case which is made from expanded insulating resin and which stores the holding frame, and an elastic member secured to the holding frame and arranged between the battery module and the case, wherein the elastic member includes an upper wall and flanges extending from both side edges of the upper wall, and wherein a distance between the flanges is substantially the same as a width of a protrusion of the holding frame for securing the elastic member to the holding frame.

摘要翻译： 电池盒结构包括电池模块，保持电池模块的保持框架，由膨胀绝缘树脂制成并存储保持框架的壳体，以及固定到保持框架并布置在电池模块和 所述弹性构件包括上壁和从所述上壁的两个侧边缘延伸的凸缘，并且所述凸缘之间的距离与用于将所述弹性构件固定的所述保持框架的突起的宽度基本相同 保持框架。

公开(公告)号：US20100120844A1

公开(公告)日：2010-05-13

申请号：US12531318

申请日：2008-04-03

申请人： Seiichi Sato ,  Junya Tagashira ,  Shunji Takemura ,  Yoshiharu Miyake ,  Tetsuya Ishikawa ,  Toshiharu Arai ,  Takahiro Ito ,  Takuya Hara

发明人： Seiichi Sato ,  Junya Tagashira ,  Shunji Takemura ,  Yoshiharu Miyake ,  Tetsuya Ishikawa ,  Toshiharu Arai ,  Takahiro Ito ,  Takuya Hara

IPC分类号： A61K31/4709 ,  C07D401/02 ,  C07D217/18 ,  A61K31/47 ,  A61P11/06 ,  A61P31/18 ,  A61P37/06 ,  A61P1/00

CPC分类号： C07D217/04 ,  A61K31/472 ,  A61K31/4725 ,  C07D217/02 ,  C07D217/14 ,  C07D401/06 ,  C07D401/12 ,  C07D401/14 ,  C07D405/12 ,  C07D409/12 ,  C07D409/14 ,  C07D417/12

摘要： The present invention relates a specific tetrahydroisoquinoline compound which is useful as a chemokine receptor type 3 (CCR3) antagonist, and a pharmaceutical composition comprising the same as an active ingredient. The tetrahydroisoquinoline compound of the present invention is useful for the treatment or prevention of a disease in which CCR3 participates.

摘要翻译： 本发明涉及可用作3型趋化因子受体（CCR3）拮抗剂的特定四氢异喹啉化合物，以及包含其作为活性成分的药物组合物。 本发明的四氢异喹啉化合物可用于治疗或预防CCR3参与的疾病。

公开(公告)号：US20080196957A1

公开(公告)日：2008-08-21

申请号：US11440364

申请日：2006-05-25

申请人： Eiji Koike ,  Harumi Takedomi ,  Satoyoshi Oya ,  Kanae Ohkuma ,  Seiichi Sato

发明人： Eiji Koike ,  Harumi Takedomi ,  Satoyoshi Oya ,  Kanae Ohkuma ,  Seiichi Sato

IPC分类号： B60R16/04

CPC分类号： H01M2/1077 ,  B60K1/04 ,  B60K2001/005 ,  B60K2001/0416 ,  B60L3/0007 ,  B60L11/1874 ,  B60L11/1877 ,  B60L11/1879 ,  B60L2240/36 ,  H01M2/1083 ,  H01M10/613 ,  H01M10/625 ,  H01M10/6563 ,  H01M10/6566 ,  H01M10/667 ,  Y02T10/7005 ,  Y02T10/705

摘要： A battery box housing a battery is mounted between left and right side frames extending in a longitudinal direction of a vehicle body so that the battery box is offset to a left side of the vehicle body, and an intake duct and an exhaust duct for cooling air for cooling the battery are connected to an end of the battery box on a right side of the vehicle body. Therefore, it is possible not only to protect the battery between the left and right frames from a shock caused upon a side collision, but also to ensure a space for disposition of the intake duct and the exhaust duct while ensuring a volume of the battery box to the maximum. Moreover, the battery box is connected at its left and right ends to the left and right side frames.

摘要翻译： 容纳电池的电池盒安装在沿着车体的纵向方向延伸的左右侧框架之间，使得电池盒偏移到车体的左侧，以及用于冷却空气的进气管道和排气管道 为了冷却电池，连接到车身右侧的电池盒的一端。 因此，不仅可以保护左右框架之间的电池免受因侧面碰撞引起的冲击，还可以确保用于配置进气管道和排气管道的空间，同时确保电池盒的体积 到最大。 此外，电池盒的左右两端连接左侧和右侧。

公开(公告)号：USD508858S1

公开(公告)日：2005-08-30

申请号：US29215057

申请日：2004-10-12

申请人： Seiichi Sato ,  Yoshinori Ito

设计人： Seiichi Sato ,  Yoshinori Ito

公开(公告)号：US06861428B2

公开(公告)日：2005-03-01

申请号：US10396726

申请日：2003-03-26

申请人： Yoshinori Kyotani ,  Tomoyuki Koshi ,  Hiromichi Shigyo ,  Hideo Yoshizaki ,  Takahiro Kitamura ,  Shunji Takemura ,  Kyoko Yasuoka ,  Junko Totsuka ,  Seiichi Sato

发明人： Yoshinori Kyotani ,  Tomoyuki Koshi ,  Hiromichi Shigyo ,  Hideo Yoshizaki ,  Takahiro Kitamura ,  Shunji Takemura ,  Kyoko Yasuoka ,  Junko Totsuka ,  Seiichi Sato

IPC分类号： A61K31/50 ,  A61K31/501 ,  C07D237/14 ,  C07D237/24 ,  A61K31/51 ,  C07D237/04 ,  C07D403/06

CPC分类号： A61K31/50 ,  A61K31/501 ,  C07D237/14 ,  C07D237/24

摘要： Compounds having the formula (1): wherein R1 represents an alkyl or alkenyl group, R2 and R3 each independently represents a hydrogen atom or an alkyl, hydroxyalkyl, dihydroxyalkyl or alkynyl group, or R2 and R3 may be fused together with the adjacent nitrogen atom to form a substituted or unsubstituted, nitrogen-containing, saturated heterocyclic group, X, Y and Z each independently represents a hydrogen atom, an alkyl group, a halogen atom or the like, and n stands for an integer of from 1 to 5; and also to pharmaceutical compositions containing them. These compounds have inhibitory activity against IL-1β production, high water solubility and good oral absorbability.

摘要翻译： 具有式（1）的化合物：其中R 1表示烷基或烯基，R 2和R 3各自独立地表示氢原子或烷基，羟基烷基，二羟基烷基或炔基，或R 2 >和R 3可以与相邻的氮原子一起形成取代或未取代的含氮饱和杂环基，X，Y和Z各自独立地表示氢原子，烷基，卤素原子或 n，n表示1〜5的整数， 以及含有它们的药物组合物。 这些化合物对IL-1β生产具有抑制活性，水溶性高，口服吸收性好。