利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

60 条记录 (耗时 0.035 秒)

    Mono-phasic action potential electrogram recording catheter, and method
    1.
    发明授权
    Mono-phasic action potential electrogram recording catheter, and method 有权
    单相动作电位记录导管及方法

    公开(公告)号：US08571626B2

    公开(公告)日：2013-10-29

    申请号：US13604139

    申请日：2012-09-05

    申请人： Michael Lau ,  Randell L. Werneth ,  Timothy J. Corvi ,  Sumita Bhola ,  Mark T. Stewart ,  Michel Haissaguerre ,  Meleze Hocini

    发明人： Michael Lau ,  Randell L. Werneth ,  Timothy J. Corvi ,  Sumita Bhola ,  Mark T. Stewart ,  Michel Haissaguerre ,  Meleze Hocini

    IPC分类号： A61B5/042 ,  A61B18/14 ,  A61N1/05

    CPC分类号： A61B5/042 ,  A61B5/6858 ,  A61B18/1492 ,  A61B2018/00214 ,  A61B2018/00839 ,  A61B2018/00898 ,  A61N1/06

    摘要： Catheters and methods for obtaining monophasic action potential (“MAP”) electrograms include a flexible catheter body defining a longitudinal axis, and a distal assembly affixed to the catheter body distal end defining a distal tip. The distal assembly has at least three MAP recording electrodes, and at least one reference electrode for determining reference potential. The recording electrodes are each positioned a radial distance from the longitudinal axis in at least three different radial directions, defining a recording geometry substantially having radial symmetry. The reference electrode is a longitudinal distance from the recording geometry. Optional features include a steerable catheter shaft, one or more radio-frequency ablation electrodes, and a dedicated pacing electrode. Different possible embodiments include a dome housing having the recording electrodes in a fixed spatial arrangement, and a distal loop assembly having an array of electrodes on at least three flexible loop elements.

    摘要翻译： 用于获得单相动作电位（“MAP”）电描记图的导管和方法包括限定纵向轴线的柔性导管主体，以及固定到导管主体远端的远端组件，其限定远端尖端。 远端组件具有至少三个MAP记录电极和用于确定参考电位的至少一个参考电极。 记录电极各自在至少三个不同的径向方向上与纵向轴线径向距离，限定基本上具有径向对称性的记录几何形状。 参考电极是与记录几何形状的纵向距离。 可选功能包括可导向的导管轴，一个或多个射频消融电极和专用起搏电极。 不同的可能实施例包括具有固定空间布置的记录电极的圆顶壳体和在至少三个柔性环形元件上具有电极阵列的远端环组件。

    Multi-array monophasic action potential medical device
    2.
    发明授权
    Multi-array monophasic action potential medical device 有权
    多阵列单相动作电位医疗器械

    公开(公告)号：US08682410B2

    公开(公告)日：2014-03-25

    申请号：US13044698

    申请日：2011-03-10

    申请人： Randell L. Werneth ,  Meleze Hocini ,  Mark T. Stewart ,  Dan Wittenberger ,  Timothy J. Corvi ,  Michael Lau ,  Vinod Sharma

    发明人： Randell L. Werneth ,  Meleze Hocini ,  Mark T. Stewart ,  Dan Wittenberger ,  Timothy J. Corvi ,  Michael Lau ,  Vinod Sharma

    IPC分类号： A61B5/042 ,  A61B18/14

    CPC分类号： A61B5/0422 ,  A61B18/1492 ,  A61B2018/1467 ,  A61B2018/1472 ,  A61B2218/002

    摘要： A medical device including a catheter having a shaft with a distal portion; a first plurality of substantially hemispherical electrodes coupled to the distal portion; a second plurality of substantially hemispherical electrodes coupled to the shaft proximal of the first plurality, where the second plurality of electrodes are oriented substantially orthogonal to the first plurality of electrodes; and an additional electrode coupled to the shaft. A console may have a processor in electrical communication with the first and second plurality of electrodes and the reference electrode, the processor programmed to obtaining a monophasic action potential recording from at least one of the first and second plurality of electrodes.

    摘要翻译： 一种医疗装置，包括具有远端部的轴的导管; 耦合到所述远端部分的第一多个基本上半球形的电极; 耦合到所述第一多个的所述轴近端的第二多个基本上半球形的电极，其中所述第二多个电极定向成基本上垂直于所述第一多个电极; 以及连接到所述轴的附加电极。 控制台可以具有与第一和第二多个电极和参考电极电连通的处理器，该处理器被编程为从第一和第二多个电极中的至少一个获得单相动作电位记录。

    Cryogenic medical device with thermal guard and method
    5.
    发明授权
    Cryogenic medical device with thermal guard and method 有权
    具有保温和低温保护的低温医疗器械

    公开(公告)号：US08647336B2

    公开(公告)日：2014-02-11

    申请号：US12816479

    申请日：2010-06-16

    申请人： Randell L. Werneth

    发明人： Randell L. Werneth

    IPC分类号： A61B18/02

    CPC分类号： A61B18/02 ,  A61B18/14 ,  A61B18/18 ,  A61B2017/00243 ,  A61B2018/0022 ,  A61B2018/0212 ,  A61B2018/0262

    摘要： A medical device, system and method are provided for thermal medical treatment. A medical device for cryogenic treatment may include a tip and a thermal guard or shield. The tip may be at a distal end of a catheter shaft, having a distal surface and lateral surfaces. The thermal guard may be coupled to the catheter proximal of the distal tip, surrounding the longitudinal axis and exposing the distal surface, to resist heat transfer from body fluids to the lateral surfaces of the tip. An efficiency of heat transfer from selected tissue to be treated to the distal surface of the cryogenic tip is thereby increased.

    摘要翻译： 提供用于热疗治疗的医疗装置，系统和方法。 用于低温处理的医疗装置可以包括尖端和保护罩或护罩。 尖端可以在导管轴的远端处，具有远侧表面和侧表面。 热保护器可以耦合到远侧末端的近端的导管，围绕纵向轴线并暴露远侧表面，以抵抗从体液到尖端的侧表面的热传递。 因此，从被处理的选定组织到低温尖端的远端表面的热传递效率提高。

    Method and device for applications of selective organ cooling
    9.
    发明授权
    Method and device for applications of selective organ cooling 有权
    选择性器官冷却应用的方法和装置

    公开(公告)号：US06679907B2

    公开(公告)日：2004-01-20

    申请号：US10210819

    申请日：2002-07-31

    申请人： John D. Dobak, III ,  Juan C. Lasheras ,  Randell L. Werneth

    发明人： John D. Dobak, III ,  Juan C. Lasheras ,  Randell L. Werneth

    IPC分类号： A61F700

    CPC分类号： A61F7/12 ,  A61B2018/0212 ,  A61B2018/0262 ,  A61F2007/0056 ,  A61F2007/126

    摘要： The invention provides a method and device for heating or cooling a surrounding fluid in a feeding vessel. The device includes a catheter assembly capable of insertion to a selected feeding vessel in the vascular system of a patient. The assembly includes a heat transfer element at a distal end of the catheter assembly, the heat transfer element having a plurality of exterior surface irregularities shaped and arranged to create turbulence in a surrounding fluid, the surface irregularities having a depth at least equal to the boundary layer thickness of flow of the surrounding fluid in the feeding vessel. The assembly also includes a supply catheter to deliver a working fluid to an interior of the heat transfer element, a return catheter to return a working fluid from the interior of the heat transfer element, and a drug delivery catheter running substantially parallel to the axis of the catheter assembly. The method includes selectively controlling the temperature of a selected volume of blood in a patient by introducing a catheter assembly into a blood vessel feeding a selected volume of blood in a patient and delivering a working fluid through a supply catheter in the catheter assembly and returning the working fluid through a return catheter in the catheter assembly. Heat is transferred between a heat transfer element forming a distal end of the catheter assembly and the volume of blood in the feeding vessel. A liquid, such as a drug, is delivered through a drug delivery catheter to the volume of blood in the feeding vessel.

    摘要翻译： 本发明提供一种用于加热或冷却进料容器中的周围流体的方法和装置。 该装置包括能够插入患者血管系统中的选定进料容器的导管组件。 所述组件包括在所述导管组件的远端处的传热元件，所述传热元件具有多个外表面凹凸，其形状和布置成在周围流体中产生湍流，所述表面凹凸具有至少等于边界的深度 进料容器中周围流体的流动层厚度。 该组件还包括供应导管，用于将工作流体输送到传热元件的内部;返回导管，用于从工作流体从传热元件的内部返回;以及药物输送导管，其基本上平行于 导管组件。 该方法包括通过将导管组件引入供给患者中选定体积的血液的血管中并通过导管组件中的供应导管输送工作流体来选择性地控制患者中所选体积的血液的温度， 工作流体通过导管组件中的返回导管。 在形成导管组件的远端的传热元件和进料容器中的血液体积之间传递热量。 诸如药物的液体通过药物输送导管递送到进料容器中的血液体积。