利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

8 条记录 (耗时 0.031 秒)

    Selective Processing of Biological Material on a Microarray Substrate
    3.
    发明申请
    Selective Processing of Biological Material on a Microarray Substrate 审中-公开
    微阵列基板上生物材料的选择性处理

    公开(公告)号：US20100076185A1

    公开(公告)日：2010-03-25

    申请号：US12562543

    申请日：2009-09-18

    申请人： Nils Adey ,  Arnold Oliphant ,  Wanyuan Ao

    发明人： Nils Adey ,  Arnold Oliphant ,  Wanyuan Ao

    IPC分类号： C07H21/04 ,  C40B60/12 ,  C40B50/00

    CPC分类号： C12Q1/6837

    摘要： The present invention provides methods and systems for selectively eluting biological material from a distinct spatial location on a microarray slide. In one aspect, for example, a method for recovering biological material coupled to a microarray slide can include selecting a biological material to be recovered from the microarray slide, finding the biological material within a distinct spatial region on the microarray slide surface, and eluting at least a portion of the selected biological material from the distinct spatial region without eluting substantial amounts of non-selected biological material from regions of the microarray slide that are not within the distinct spatial region.

    摘要翻译： 本发明提供了用于从微阵列载玻片上的不同空间位置选择性洗脱生物材料的方法和系统。 在一个方面，例如，用于回收与微阵列载玻片耦合的生物材料的方法可以包括从微阵列载玻片上选择要回收的生物材料，在微阵列载玻片表面上的不同空间区域内找到生物材料，并在 来自不同空间区域的所选择的生物材料的至少一部分，而不从不在不同空间区域内的微阵列载玻片的区域洗脱大量未选择的生物材料。

    System and Method for Hybridization Slide Processing
    4.
    发明申请
    System and Method for Hybridization Slide Processing 审中-公开
    杂交幻灯片处理系统与方法

    公开(公告)号：US20100167943A1

    公开(公告)日：2010-07-01

    申请号：US12207343

    申请日：2008-09-09

    申请人： Nils Adey ,  Tom Moyer ,  Rob Parry ,  Dale Emery

    发明人： Nils Adey ,  Tom Moyer ,  Rob Parry ,  Dale Emery

    IPC分类号： C40B30/04 ,  C40B60/12

    CPC分类号： G01N35/00029 ,  G01N2035/00089 ,  G01N2035/00138

    摘要： A system for the automated hybridization of a plurality of microarray slides. The system comprises an enclosure with a wash basin having an open top end, a lower carrier rotor disposed within the wash basin on a support axle for receiving a plurality of microarray slide substrates, and an upper clamp rotor disposed above the lower carrier rotor on the support axle for receiving a plurality of disposable mixers. The system is further configured so that lowering the upper clamp rotor to engage with the lower carrier rotor couples the plurality of mixers to the plurality of slide substrates to form a plurality of sealed reaction chambers, and raising the upper clamp rotor to disengage from the lower carrier rotor de-couples the plurality of mixers from the plurality of slide substrates to unseal the plurality of reaction chambers.

    摘要翻译： 用于多个微阵列载玻片的自动杂交的系统。 该系统包括具有开放顶端的洗手盆的外壳，设置在洗手盆内的下托架转子，用于容纳多个微阵列滑动基板的支撑轴上，以及设置在下载架转子上方的上夹具转子 用于接收多个一次性混合器的支撑轴。 该系统进一步被构造成使得下夹具转子与下载体转子相接合将多个混合器耦合到多个滑动基板以形成多个密封的反应室，并且将上夹具转子升高以从下部 载体转子将多个混合器从多个滑动基板解耦，以便打开多个反应室。

    Slide Conditioning Systems and Methods
    5.
    发明申请
    Slide Conditioning Systems and Methods 审中-公开
    滑动调节系统和方法

    公开(公告)号：US20100200021A1

    公开(公告)日：2010-08-12

    申请号：US12247408

    申请日：2008-10-08

    申请人： Nils Adey ,  Tom Moyer ,  Dale Emery ,  Michael Worthen ,  Wanyuan Ao

    发明人： Nils Adey ,  Tom Moyer ,  Dale Emery ,  Michael Worthen ,  Wanyuan Ao

    IPC分类号： B08B11/02

    CPC分类号： B08B11/02 ,  B08B3/04 ,  G01N35/1095 ,  G01N2035/00237

    摘要： A slide conditioning system comprises a basin, suitable to retain fluids therein, and a slide carrier having a bidirectional valve formed therein, the slide carrier adapted to carry a plurality of slides therein. A rotor arm is rotatable relative to the basin, the rotor arm being capable of carrying the slide carrier and applying centrifugal forces to the slide carrier as the rotor arm rotates. A fluidics system is also provided and a fluid coupling port is operable to selectively and fluidly mate with the bidirectional valve of the slide carrier while the slide carrier is carried by the rotor arm to fluidly couple the slide carrier to the fluidics system.

    摘要翻译： 滑动调节系统包括适于在其中保留流体的盆，以及其中形成有双向阀的滑动载体，所述滑动载体适于在其中承载多个载玻片。 转子臂相对于盆可旋转，转子臂能够承载滑动载体并且当转子臂旋转时将离心力施加到滑动载体。 还提供流体系统，并且流体联接口可操作以选择性地和流体地配合滑动载体的双向阀，同时滑动载体由转子臂承载以将滑动载体流体耦合到流体系统。

    Modular system for performing laboratory protocols and associated methods
    6.
    发明授权
    Modular system for performing laboratory protocols and associated methods 有权
    用于执行实验室协议和相关方法的模块化系统

    公开(公告)号：US08501115B2

    公开(公告)日：2013-08-06

    申请号：US12606083

    申请日：2009-10-26

    申请人： Nils Adey ,  Rob Parry

    发明人： Nils Adey ,  Rob Parry

    IPC分类号： B01L99/00

    CPC分类号： G01N1/312 ,  B01F11/0008 ,  B01F11/0017 ,  B01L3/502715 ,  B01L7/52 ,  B01L2300/1822 ,  G01N35/00029 ,  G01N2001/315 ,  G01N2035/00039 ,  G01N2035/00089 ,  G01N2035/00138 ,  G01N2035/00326

    摘要： Systems, devices, and methods for automating laboratory protocols utilizing modular processing components to allow systems to be reconfigured for processing a wide variety of disparate laboratory protocols are provided. In one aspect, a sample processing module is provided, including a housing configured to accommodate a pre-identified sample process, a standardized temperature input capable of interfacing with a temperature controller, a standardized fluid input capable of interfacing with an input fluid controller, and a standardized agitation connector capable of interfacing with an agitator. These standardized components provide interchangeability of the module with a module having a housing configured to accommodate a different pre-identified sample process in a sample processing system.

    摘要翻译： 提供了使用模块化处理组件自动化实验室协议以允许系统重新配置以处理各种不同实验室协议的系统，设备和方法。 在一个方面，提供了一种样品处理模块，其包括构造成容纳预先识别的样品过程的壳体，能够与温度控制器接口的标准化温度输入，能够与输入流体控制器接口的标准化流体输入，以及 能够与搅拌器连接的标准化搅拌连接器。 这些标准化组件提供了模块与具有壳体的模块的可互换性，该壳体被配置为在样本处理系统中适应不同的预先识别的样本过程。

    SYSTEM AND METHOD FOR HYBRIDIZATION SLIDE PROCESSING
    7.
    发明申请
    SYSTEM AND METHOD FOR HYBRIDIZATION SLIDE PROCESSING 审中-公开
    用于混合滑动加工的系统和方法

    公开(公告)号：US20110190153A1

    公开(公告)日：2011-08-04

    申请号：US12997238

    申请日：2009-06-09

    申请人： Nils Adey ,  Tom Moyer ,  Rob Parry ,  Dale Emery

    发明人： Nils Adey ,  Tom Moyer ,  Rob Parry ,  Dale Emery

    IPC分类号： C40B30/04 ,  C40B60/12

    CPC分类号： C40B30/04 ,  C40B60/12

    摘要： A system 300 for the substantially-automated hybridization of a plurality of microarray slides. The system comprises an enclosure 310 with a wash basin 312 having an open top end, a lower carrier rotor 330 disposed within the wash basin on a support axle 318 for receiving a plurality of microarray slide substrates 362, and an upper clamp rotor 340 disposed above the lower carrier rotor on the support axle for receiving a plurality of disposable chamber assemblies 240. The system is further configured so that lowering the upper clamp rotor to engage with the lower carrier rotor couples the plurality of chamber assemblies to the plurality of slide substrates to form a plurality of sealed reaction chambers 244, and raising the upper clamp rotor to disengage from the lower carrier rotor de-couples the plurality of chamber assemblies from the plurality of slide substrates to unseal the plurality of reaction chambers.

    摘要翻译： 一种用于多个微阵列载片的基本上自动化杂交的系统300。 该系统包括具有敞开的顶端的洗手盆312的外壳310，设置在洗手盆内的下托架转子330，其位于支撑轴318上，用于容纳多个微阵列滑动基板362，以及设置在上方的上夹具转子340 支撑轴上的下承载转子用于容纳多个一次性室组件240.该系统进一步构造成使得下夹具转子与下承载转子相接合将多个室组件连接到多个滑动衬底上 形成多个密封反应室244，并且升高上夹具转子以与下载体转子脱离，使多个室组件与多个滑动基板脱离接合以开启多个反应室。

    Modular System for Performing Laboratory Protocols and Associated Methods
    8.
    发明申请
    Modular System for Performing Laboratory Protocols and Associated Methods 有权
    用于执行实验室协议和相关方法的模块化系统

    公开(公告)号：US20100113288A1

    公开(公告)日：2010-05-06

    申请号：US12606083

    申请日：2009-10-26

    申请人： Nils Adey ,  Rob Parry

    发明人： Nils Adey ,  Rob Parry

    IPC分类号： C40B30/00 ,  G05D9/00 ,  C40B60/00 ,  C12M1/36 ,  C12Q1/68

    CPC分类号： G01N1/312 ,  B01F11/0008 ,  B01F11/0017 ,  B01L3/502715 ,  B01L7/52 ,  B01L2300/1822 ,  G01N35/00029 ,  G01N2001/315 ,  G01N2035/00039 ,  G01N2035/00089 ,  G01N2035/00138 ,  G01N2035/00326

    摘要： Systems, devices, and methods for automating laboratory protocols utilizing modular processing components to allow systems to be reconfigured for processing a wide variety of disparate laboratory protocols are provided. In one aspect, a sample processing module is provided, including a housing configured to accommodate a pre-identified sample process, a standardized temperature input capable of interfacing with a temperature controller, a standardized fluid input capable of interfacing with an input fluid controller, and a standardized agitation connector capable of interfacing with an agitator. These standardized components provide interchangeability of the module with a module having a housing configured to accommodate a different pre-identified sample process in a sample processing system.

    摘要翻译： 提供了使用模块化处理组件自动化实验室协议以允许系统重新配置以处理各种不同实验室协议的系统，设备和方法。 在一个方面，提供了一种样品处理模块，其包括构造成容纳预先识别的样品过程的壳体，能够与温度控制器接口的标准化温度输入，能够与输入流体控制器接口的标准化流体输入，以及 能够与搅拌器连接的标准化搅拌连接器。 这些标准化组件提供了模块与具有壳体的模块的可互换性，该壳体被配置为在样本处理系统中适应不同的预先识别的样本过程。