-
公开(公告)号:US08969066B2
公开(公告)日:2015-03-03
申请号:US13001027
申请日:2009-06-26
申请人: Michael Mendez , Craig Behnke , Yan Poon , Philip Lee
发明人: Michael Mendez , Craig Behnke , Yan Poon , Philip Lee
IPC分类号: C12N15/87 , C12N1/02 , C12N1/13 , C12P21/00 , C12P19/00 , B03D3/06 , C12N15/62 , C12N1/12 , C07K14/47 , C07K16/16
CPC分类号: C12N1/12 , C07K14/4726 , C07K16/16 , C12N1/02
摘要: The present invention provides compositions and methods for producing flocculation moieties in photosynthetic organisms. The photosynthetic organisms are genetically modified to effect production, secretion, or both, of the flocculation moieties. Also provided are methods of flocculating organisms.
摘要翻译: 本发明提供了用于在光合生物体中产生絮凝部分的组合物和方法。 光合生物被遗传修饰以影响絮凝部分的产生,分泌或两者。 还提供了絮凝生物体的方法。
-
公开(公告)号:US20110159595A1
公开(公告)日:2011-06-30
申请号:US13001027
申请日:2009-06-26
申请人: Michael Mendez , Craig Behnke , Yan Poon , Philip Lee
发明人: Michael Mendez , Craig Behnke , Yan Poon , Philip Lee
IPC分类号: C12N15/74
CPC分类号: C12N1/12 , C07K14/4726 , C07K16/16 , C12N1/02
摘要: The present invention provides compositions and methods for producing flocculation moieties in photosynthetic organisms. The photosynthetic organisms are genetically modified to effect production, secretion, or both, of the flocculation moieties. Also provided are methods of flocculating organisms.
摘要翻译: 本发明提供了用于在光合生物体中产生絮凝部分的组合物和方法。 光合生物被遗传修饰以影响絮凝部分的产生,分泌或两者。 还提供了絮凝生物体的方法。
-
公开(公告)号:US20090204598A1
公开(公告)日:2009-08-13
申请号:US12028628
申请日:2008-02-08
申请人: Andrew S. Crane , Philip Lee , Dou Shen
发明人: Andrew S. Crane , Philip Lee , Dou Shen
IPC分类号: G06F17/30
CPC分类号: G06F17/30867 , G06F17/30864 , G06Q30/02
摘要: In this invention, systems and methods for providing keywords for advertising are provided. After a user searches for another user in a social network, the webpage or blog of the queried user is retrieved, and keywords are extracted from this webpage. The keywords may be extracted from the user's profile on the social network (e.g., favorite sports, music artists, etc.), or keywords may be extracted from the text of the webpage (e.g., comments that comprise the blog entries). Once extracted, these keywords may then be used by an advertising system to provide targeted advertisements to the user.
摘要翻译: 在本发明中,提供了用于提供用于广告的关键字的系统和方法。 在用户搜索社交网络中的另一用户之后,检索查询用户的网页或博客,并从该网页中提取关键字。 可以从用户在社交网络(例如喜爱的运动,音乐艺术家等)上的简档中提取关键字,或者可以从网页的文本(例如,包括博客条目的评论)中提取关键字。 一旦提取,这些关键字然后可以被广告系统用于向用户提供有针对性的广告。
-
公开(公告)号:US20070275455A1
公开(公告)日:2007-11-29
申请号:US11648207
申请日:2006-12-29
申请人: Paul Hung , Philip Lee
发明人: Paul Hung , Philip Lee
IPC分类号: C12M1/34
CPC分类号: C12M23/12 , B01L3/5025 , B01L3/502707 , B01L3/502715 , B01L3/50273 , B01L3/502738 , B01L3/502746 , B01L2200/12 , B01L2300/0681 , B01L2300/0816 , B01L2300/0819 , B01L2300/10 , B01L2300/123 , B01L2300/14 , B01L2400/0481 , B01L2400/0487 , B01L2400/0655 , B29C65/002 , C12M23/16 , C12M29/10 , C12M29/14 , C12M41/00 , C12M41/48 , C12Q1/025 , F16K27/0236 , F16K99/0001 , F16K99/0015 , F16K99/0059 , F16K2099/0074 , F16K2099/0078 , F16K2099/0084 , G01N33/5008 , G01N33/54366 , G01N2035/00158 , Y10T137/2202
摘要: A valved microfluidics device, microfluidics cell-culture device and system incorporating the devices are disclosed. The valved microfluidics device includes a substrate, a microchannel through which liquid can be moved from one station to another within the device, and a pneumatic microvalve adapted to be switched between open and closed states to control the flow of fluid through a microchannel. The microvalve is formed of three flexible membranes, one of which is responsive to pneumatic pressure applied to the valve and the other two of which deform to produce a more sealable channel cross-section. The cell culture device provides valving to allow controlled loading of cells into the individual well of the device, and exchange of cell-culture components in the wells.
摘要翻译: 公开了一种带阀的微流体装置,微流体细胞培养装置和结合装置的系统。 带阀的微流体装置包括基底,微通道,通过该微通道液体可以在装置内从一个站移动到另一个站;以及气动微型阀,其适于在打开和关闭状态之间切换以控制通过微通道的流体流动。 微型阀由三个柔性膜形成,其中一个柔性膜响应于施加到阀上的气压,另外两个变形以产生更可密封的通道横截面。 细胞培养装置提供阀门以允许将细胞控制加载到装置的个体井中,以及在孔中交换细胞培养组分。
-
公开(公告)号:US5265608A
公开(公告)日:1993-11-30
申请号:US802953
申请日:1991-12-05
申请人: Philip Lee , Kenneth Stokes , Michael Colson
发明人: Philip Lee , Kenneth Stokes , Michael Colson
CPC分类号: A61N1/0556
摘要: An improved electrode for establishing electrical contact with a nerve of a patient. This electrical contact may be used to sense neural activity on the nerve or to artificially stimulate it to perform various medical treatments. One embodiment of the electrode has an outer cuff of an insulating material which is sutured around the nerve to be contacted. A drug impregnated layer of material is positioned inside of the outer cuff. This material is a polymeric matrix which permits the drug to leach out at a predetermined rate. The drug is preferably a glucocortico steroid such as dexamethasone sodium phosphate. The actual electrical contact is produced by metallic foil which is positioned on the surface of the drug impregnated layer of material which is located inside of the cuff. A second embodiment employs a half cuff which is held in contact with the nerve tissue by being sutured to muscle tissue. The insulative substrate of the half cuff is a drug impregnated polymeric matrix. The electrode is a metallic disc, preferably round or oval in shape, which is recessed into the insulative substrate. An insulated lead electrically couples the metallic foil or metallic disc to an electronic circuit located remote from the nerve. The leaching out of the drug serves to control inflammation, irritation and swelling, and stabilizes the impedance and threshold of the nerve/electrode interface.
摘要翻译: 用于与患者的神经建立电接触的改进的电极。 该电接触可用于感测神经上的神经活动或人为地刺激其进行各种医学治疗。 电极的一个实施例具有绝缘材料的外箍,其被缝合在要接触的神经周围。 药物浸渍的材料层位于外箍内侧。 该材料是允许药物以预定速率浸出的聚合物基质。 该药物优选为葡萄糖皮质类固醇,例如地塞米松磷酸钠。 实际的电接触由金属箔制成,该金属箔位于位于袖带内部的药物浸渍材料层的表面上。 第二实施例采用通过缝合到肌肉组织而与神经组织保持接触的半箍。 半箍的绝缘底物是药物浸渍的聚合物基质。 电极是金属盘,优选为圆形或椭圆形,其凹入绝缘基底。 绝缘引线将金属箔或金属盘电耦合到远离神经的电子电路。 药物中的浸出物用于控制炎症,刺激和肿胀,稳定神经/电极界面的阻抗和阈值。
-
公开(公告)号:US08122878B1
公开(公告)日:2012-02-28
申请号:US11974683
申请日:2007-10-15
申请人: William Gross , Philip Lee , Kevin Hickerson , Dylan Owens , Peter Polidoro
发明人: William Gross , Philip Lee , Kevin Hickerson , Dylan Owens , Peter Polidoro
IPC分类号: F24J2/38
摘要: The invention in the preferred embodiment features a solar concentrator that can align and/or track based on images from a video camera, for example. The concentrator preferably includes one or more optical elements for directing light to a receiver, a camera for capturing an image of the optical elements, and a controller configured to: detect the orientation of the one or more optical elements from the one or more images, determine an orientation error based on the detected orientation, and automatically orient the one or more optical elements to minimize the orientation error. The optical elements generally comprise a plurality of mirrors or lenses arranged in a one or two dimensional array.
摘要翻译: 在优选实施例中的本发明具有基于例如基于来自摄像机的图像对准和/或跟踪的太阳能集中器。 聚光器优选地包括用于将光引导到接收器的一个或多个光学元件,用于捕获光学元件的图像的相机以及被配置为:从一个或多个图像检测一个或多个光学元件的取向的控制器, 基于检测到的方向来确定取向误差,并且自动地定向一个或多个光学元件以最小化定向误差。 光学元件通常包括以一维或二维阵列布置的多个反射镜或透镜。
-
公开(公告)号:US20070217640A1
公开(公告)日:2007-09-20
申请号:US11752196
申请日:2007-05-22
申请人: Albert Maltan , Alfred Mann , James McGivern , Philip Lee
发明人: Albert Maltan , Alfred Mann , James McGivern , Philip Lee
IPC分类号: H04R25/00
CPC分类号: H04R25/505 , H04R25/554 , H04R25/558 , H04R25/60 , H04R25/65 , H04R25/658 , H04R2225/51 , H04R2225/67 , H04R2420/07
摘要: A hearing aid module is shaped for insertion into a tunnel made through the soft tissue that connects the retro-auricular space with the ear canal. The hearing aid module contains a speaker or auditory transducer, a battery or other power source powering the module, signal processing circuitry, a microphone, and a hollow tube which contains a steroid or drug. Telemetry circuitry within the module allows the signal processing circuitry to be programmed with a desired frequency response or signal processing strategy using an external programming unit. A remote control unit permits the user to make simple adjustments, such as volume and/or tone (frequency) control.
摘要翻译: 助听器模块被成形为插入到通过将耳环空间与耳道连接的软组织制成的隧道中。 助听器模块包含扬声器或听觉换能器,为模块供电的电池或其它电源,信号处理电路,麦克风和含有类固醇或药物的中空管。 模块内的遥测电路允许使用外部编程单元对信号处理电路进行所需的频率响应或信号处理策略的编程。 遥控单元允许用户进行简单的调节,例如音量和/或音调(频率)控制。
-
公开(公告)号:US20060129201A1
公开(公告)日:2006-06-15
申请号:US11295783
申请日:2005-12-06
申请人: Philip Lee , Todd Whitehurst , Carla Woods
发明人: Philip Lee , Todd Whitehurst , Carla Woods
IPC分类号: A61N1/08
CPC分类号: A61N1/36007 , A61N1/05
摘要: Systems for treating an obese patient include one or more sensors configured to sense one or more physical parameters of the patient and one or more implanted stimulators configured to apply a stimulus to the stomach in response to the sensed parameters. Methods of treating an obese patient include sensing one or more physical parameters of the patient and applying a stimulus to the stomach with one or more implanted stimulators in response to the sensed parameters.
-
公开(公告)号:US20060088579A1
公开(公告)日:2006-04-27
申请号:US10503826
申请日:2003-02-07
申请人: Venkatram Shastri , Philip Lee , Samir Mitragotri , Robert Langer
发明人: Venkatram Shastri , Philip Lee , Samir Mitragotri , Robert Langer
CPC分类号: A61K47/10 , A61K9/0014 , A61K9/1075 , A61K47/06 , A61K47/12 , A61K47/14 , A61K47/22
摘要: One aspect of the invention provides a transdermal delivery system including a drug formulated with a transport chaperone moiety that reversibly associates with the drug. The chaperone moiety is associated with the drug in the formulation so as to enhance transport of the drug across dermal tissue and releasing the drug after crossing said dermal tissue.
摘要翻译: 本发明的一个方面提供了一种透皮递送系统,其包括与可与药物可逆地结合的转运伴侣部分配制的药物。 分子伴侣部分与制剂中的药物相关联,以便增强药物穿过真皮组织的转运并在穿过所述皮肤组织后释放药物。
-
公开(公告)号:US08768922B2
公开(公告)日:2014-07-01
申请号:US12028628
申请日:2008-02-08
申请人: Andrew S. Crane , Philip Lee , Dou Shen
发明人: Andrew S. Crane , Philip Lee , Dou Shen
IPC分类号: G06F17/30
CPC分类号: G06F17/30867 , G06F17/30864 , G06Q30/02
摘要: In this invention, systems and methods for providing keywords for advertising are provided. After a user searches for another user in a social network, the webpage or blog of the queried user is retrieved, and keywords are extracted from this webpage. The keywords may be extracted from the user's profile on the social network (e.g., favorite sports, music artists, etc.), or keywords may be extracted from the text of the webpage (e.g., comments that comprise the blog entries). Once extracted, these keywords may then be used by an advertising system to provide targeted advertisements to the user.
摘要翻译: 在本发明中,提供了用于提供用于广告的关键字的系统和方法。 在用户搜索社交网络中的另一用户之后,检索查询用户的网页或博客,并从该网页中提取关键字。 可以从用户在社交网络(例如喜爱的运动,音乐艺术家等)上的简档中提取关键字,或者可以从网页的文本(例如,包括博客条目的评论)中提取关键字。 一旦提取,这些关键字然后可以被广告系统用于向用户提供有针对性的广告。
-
-
-
-
-
-
-
-
-