公开(公告)号：US09456798B2

公开(公告)日：2016-10-04

申请号：US14710052

申请日：2015-05-12

申请人： Ming Xue ,  Wei Lu ,  Seth Kligerman ,  Hao Zhang ,  Warren D'Souza ,  Wookjin Choi

发明人： Ming Xue ,  Wei Lu ,  Seth Kligerman ,  Hao Zhang ,  Warren D'Souza ,  Wookjin Choi

IPC分类号： G06K9/00 ,  A61B6/00 ,  G06T7/00 ,  G06T11/00 ,  A61B6/03

CPC分类号： A61B6/545 ,  A61B6/032 ,  A61B6/481 ,  A61B6/486 ,  A61B6/504 ,  G06T7/0012 ,  G06T11/006 ,  G06T2207/10081 ,  G06T2207/20104 ,  G06T2207/30101 ,  G06T2211/404

摘要： A method is provided for optimizing a contrast injection function for CT imaging. The method includes injecting, with an injector pump, a test bolus of a contrast agent into a subject. The method also includes computing, on a processor, an impulse enhancement function. The method also includes determining, on a processor, a target enhancement function for a region of interest. The method also includes determining, with a processor, a plurality of parameters for a functional form for a contrast injection function in a time domain. The method also includes determining for the contrast injection function a constraint. The method also includes determining, with a processor, particular values for the plurality of parameters, which satisfy the constraint and minimize a difference between a value of an enhancement function and the target enhancement function computed in the time domain at discrete time periods without use of a Fourier transform.

摘要翻译： 提供了一种用于优化CT成像的造影剂注射功能的方法。 该方法包括用注射器泵将造影剂的测试团注入受试者。 该方法还包括在处理器上计算脉冲增强功能。 该方法还包括在处理器上确定感兴趣区域的目标增强功能。 该方法还包括使用处理器确定用于时域中的对比度注入功能的功能形式的多个参数。 该方法还包括确定对比度注入功能的约束。 该方法还包括使用处理器确定满足约束的多个参数的特定值，并且使离散时间段内在增强函数的值和在时域中计算的目标增强函数之间的差最小化，而不使用 傅立叶变换。

公开(公告)号：US20150324979A1

公开(公告)日：2015-11-12

申请号：US14710052

申请日：2015-05-12

申请人： Ming Xue ,  Wei Lu ,  Seth Kligerman ,  Hao Zhang ,  Warren D'Souza ,  Wookjin Choi

发明人： Ming Xue ,  Wei Lu ,  Seth Kligerman ,  Hao Zhang ,  Warren D'Souza ,  Wookjin Choi

IPC分类号： G06T7/00 ,  G06T11/00

CPC分类号： A61B6/545 ,  A61B6/032 ,  A61B6/481 ,  A61B6/486 ,  A61B6/504 ,  G06T7/0012 ,  G06T11/006 ,  G06T2207/10081 ,  G06T2207/20104 ,  G06T2207/30101 ,  G06T2211/404

摘要： A method is provided for optimizing a contrast injection function for CT imaging. The method includes injecting, with an injector pump, a test bolus of a contrast agent into a subject. The method also includes computing, on a processor, an impulse enhancement function. The method also includes determining, on a processor, a target enhancement function for a region of interest. The method also includes determining, with a processor, a plurality of parameters for a functional form for a contrast injection function in a time domain. The method also includes determining for the contrast injection function a constraint. The method also includes determining, with a processor, particular values for the plurality of parameters, which satisfy the constraint and minimize a difference between a value of an enhancement function and the target enhancement function computed in the time domain at discrete time periods without use of a Fourier transform.

摘要翻译： 提供了一种用于优化CT成像的造影剂注射功能的方法。 该方法包括用注射器泵将造影剂的测试团注入受试者。 该方法还包括在处理器上计算脉冲增强功能。 该方法还包括在处理器上确定感兴趣区域的目标增强功能。 该方法还包括使用处理器确定用于时域中的对比度注入功能的功能形式的多个参数。 该方法还包括确定对比度注入功能的约束。 该方法还包括使用处理器确定满足约束的多个参数的特定值，并且使离散时间段内在增强函数的值和在时域中计算的目标增强函数之间的差最小化，而不使用 傅立叶变换。

公开(公告)号：US08747382B2

公开(公告)日：2014-06-10

申请号：US13172010

申请日：2011-06-29

申请人： Warren D'Souza ,  Hao Zhang ,  Kathleen Malinowski

发明人： Warren D'Souza ,  Hao Zhang ,  Kathleen Malinowski

IPC分类号： A61M31/00

CPC分类号： A61B5/704 ,  A61B5/087 ,  A61B5/1114 ,  A61B5/1127 ,  A61B5/1135 ,  A61B6/032 ,  A61B6/12 ,  A61B6/5217 ,  A61N5/1045 ,  A61N5/1049 ,  A61N5/1067 ,  A61N5/107

摘要： One embodiment includes a method of predicting a position of a target site inside a body using surrogates is provided. The method includes transforming surrogate measurements and target positions into different representations by applying an operator, establishing a special relationship between the transformed surrogate measurements and the transformed target positions, and continuously predicting the target position from the transformed surrogate measurements and the established special relationship.

摘要翻译： 一个实施例包括提供使用替代物来预测身体内的目标部位的位置的方法。 该方法包括通过应用运算符将​​代理测量和目标位置转换成不同的表示，在变换的替代测量与变换的目标位置之间建立特殊的关系，以及从变换后的代理测量和建立的特殊关系连续地预测目标位置。

公开(公告)号：US07790617B2

公开(公告)日：2010-09-07

申请号：US11273108

申请日：2005-11-12

申请人： Yeow Kheng Lim ,  Wei Lu ,  Liang Choo Hsia ,  Jyoti Gupta ,  Chim Seng Seet ,  Hao Zhang

发明人： Yeow Kheng Lim ,  Wei Lu ,  Liang Choo Hsia ,  Jyoti Gupta ,  Chim Seng Seet ,  Hao Zhang

IPC分类号： H01L21/441

CPC分类号： H01L21/76831 ,  H01L21/2855 ,  H01L21/76849 ,  H01L21/76877

摘要： A method of fabrication of a sputtered metal silicide layer over a copper interconnect. We form a dielectric layer over a conductive layer. We form an interconnect opening in the dielectric layer. We form a copper layer at least filling the interconnect opening. We planarize the copper layer to form a copper interconnect in the interconnect opening. The copper interconnect is over polished to form a depression. We form metal silicide layer over the copper interconnect using a low temperature sputtering process. We can form a cap layer over the metal silicide layer.

摘要翻译： 一种在铜互连上制造溅射金属硅化物层的方法。 我们在导电层上形成介电层。 我们在电介质层中形成互连开口。 我们形成至少填充互连开口的铜层。 我们平面化铜层以在互连开口中形成铜互连。 铜互连件被抛光以形成凹陷。 我们使用低温溅射工艺在铜互连上形成金属硅化物层。 我们可以在金属硅化物层上形成覆盖层。

公开(公告)号：US20070111522A1

公开(公告)日：2007-05-17

申请号：US11273108

申请日：2005-11-12

申请人： Yeow Lim ,  Wei Lu ,  Liang Hsia ,  Jyoti Gupta ,  Chim Seet ,  Hao Zhang

发明人： Yeow Lim ,  Wei Lu ,  Liang Hsia ,  Jyoti Gupta ,  Chim Seet ,  Hao Zhang

IPC分类号： H01L21/44

CPC分类号： H01L21/76831 ,  H01L21/2855 ,  H01L21/76849 ,  H01L21/76877

摘要： A method of fabrication of a sputtered metal silicide layer over a copper interconnect. We form a dielectric layer over a conductive layer. We form an interconnect opening in the dielectric layer. We form a copper layer at least filling the interconnect opening. We planarize the copper layer to form a copper interconnect in the interconnect opening. The copper interconnect is over polished to form a depression. We form metal silicide layer over the copper interconnect using a low temperature sputtering process. We can form a cap layer over the metal silicide layer.

摘要翻译： 一种在铜互连上制造溅射金属硅化物层的方法。 我们在导电层上形成介电层。 我们在电介质层中形成互连开口。 我们形成至少填充互连开口的铜层。 我们平面化铜层以在互连开口中形成铜互连。 铜互连件被抛光以形成凹陷。 我们使用低温溅射工艺在铜互连上形成金属硅化物层。 我们可以在金属硅化物层上形成覆盖层。

公开(公告)号：US11727583B2

公开(公告)日：2023-08-15

申请号：US17010372

申请日：2020-09-02

申请人： Hao Zhang ,  Stephen Dymmock ,  Nora Patricia Alarcon ,  Fei Le

发明人： Hao Zhang ,  Stephen Dymmock ,  Nora Patricia Alarcon ,  Fei Le

IPC分类号： G06T7/50 ,  E21B47/002 ,  G06T3/40 ,  E21B47/12

CPC分类号： G06T7/50 ,  E21B47/0025 ,  G06T3/4053 ,  E21B47/12

摘要： A method for characterizing a subsurface formation includes receiving image data of the subsurface formation obtained by a sensor tool and receiving a plurality of non-image data logs, each non-image data log being obtained by a different type of sensor tool. The method also includes performing an electrofacies analysis on the plurality of non-image data logs where the electrofacies analysis includes defining clusters wherein each cluster has a similar property to provide a plurality of electrofacies blocks with each electrofacies block representing a depth interval. The method further includes partitioning the image data into multiple high-resolution depth segments that share a similar property, feature, and/or pattern for each electrofacies block and assigning data from the plurality of non-image data logs into a corresponding high-resolution depth segment to provide a high-resolution data log that characterizes the subsurface formation.

公开(公告)号：US11499686B1

公开(公告)日：2022-11-15

申请号：US17479736

申请日：2021-09-20

申请人： Daniel Machlis ,  Eva Lu ,  Hao Zhang

发明人： Daniel Machlis ,  Eva Lu ,  Hao Zhang

IPC分类号： F21S4/28 ,  F21V5/04 ,  F21Y103/10 ,  F21Y115/10

摘要： An x-axis curvable LED lighting system includes an elongated notched x-axis curved channel enclosed in a casing which can be freely bent without a machine having a bottom portion and one or more walls extending therefrom; an elongated lens to secure over a top of the elongated curved channel; and a flexible light strip, having a mounting strip to secure to one of the one or more walls of the elongated curved channel; LED lights attached to the mounting strip by an extension such that the LED lights are positioned within the elongated curved channel along the bottom portion; the LED lights emit light through the elongated lens.

公开(公告)号：US20220017886A1

公开(公告)日：2022-01-20

申请号：US17497963

申请日：2021-10-10

申请人： Haiqin Chen ,  Bo Yang ,  He Gao ,  Jianxin Zhao ,  Yongquan Chen ,  Hao Zhang ,  Wei Chen

发明人： Haiqin Chen ,  Bo Yang ,  He Gao ,  Jianxin Zhao ,  Yongquan Chen ,  Hao Zhang ,  Wei Chen

IPC分类号： C12N9/90 ,  C12P7/64

摘要： Disclosed is linoleic acid isomerases and their application in production of conjugated linoleic acid, which belongs to the technical fields of protein engineering and microbial engineering. The linoleic acid isomerase derived from Bifidobacterium is used to produce the conjugated linoleic acid. The recombinant E. coli containing the linoleic acid isomerase of the invention is added into a reaction system containing linoleic acid and react for 3 h to produce conjugated linoleic acids. The conversion rate of the conjugated linoleic acid of the invented method ranges from 12.1% to 42.1%, and the percentage of cis9, trans11-CLA in the conjugated linoleic acid can reach 84.3% to 89.1%. The invention provides a method for using microorganisms to produce conjugated linoleic acids with high safety and yield where cis9, trans11-CLA isomer is the major form in the conjugated linoleic acid products.

公开(公告)号：US20210403884A1

公开(公告)日：2021-12-30

申请号：US17469899

申请日：2021-09-09

申请人： Haiqin Chen ,  Wei Chen ,  Xin Tang ,  Jun Cao ,  Jianxin Zhao ,  Yongquan Chen ,  Hao Zhang

发明人： Haiqin Chen ,  Wei Chen ,  Xin Tang ,  Jun Cao ,  Jianxin Zhao ,  Yongquan Chen ,  Hao Zhang

IPC分类号： C12N9/10 ,  C12P7/64

摘要： Disclosed is a diacylglycerol acyltransferase 1, a recombinant Saccharomyces cerevisiae containing the diacylglycerol acyltransferase 1, and application thereof in production of triacylglycerol. The diacylglycerol acyltransferase 1 of the invention has a function of catalyzing synthesis of triacylglycerol. After the recombinant Saccharomyces cerevisiae containing the diacylglycerol acyltransferase 1 of the invention is subjected to induction culture for 48 h, the content of total fatty acid and triacylglycerol in the recombinant Saccharomyces cerevisiae containing the diacylglycerol acyltransferase 1 can be respectively increased by 1.94 folds and 12.09 folds as compared with those of Saccharomyces cerevisiae without the recombinant diacylglycerol acyltransferase 1. The instant invention provides a method for improving the ability of microorganisms to produce polyunsaturated fatty acids (PUFAs) by means of genetic engineering.

公开(公告)号：US20190235109A1

公开(公告)日：2019-08-01

申请号：US15883817

申请日：2018-01-30

申请人： Hao Zhang ,  Alberto Mezzatesta

发明人： Hao Zhang ,  Alberto Mezzatesta

IPC分类号： G01V1/30 ,  E21B7/06 ,  G01V1/50 ,  C09K8/62 ,  E21B49/00 ,  G01V1/28 ,  G01V5/10 ,  G01V3/08 ,  G01V99/00

摘要： Examples of techniques for generating a high-resolution lithology model for subsurface formation evaluation are disclosed. In one example implementation according to aspects of the present disclosure, a computer-implemented method includes determining, by a processing device, a low-resolution lithology volumetric model. The method further includes comparing, by the processing device, the low-resolution lithology volumetric model to a high-resolution imaging log. The method further includes calculating, by the processing device, a dynamic boundary curve for each of a plurality of moving windows. The method further includes generating, by the processing device, the high-resolution lithology model based at least in part on the calculated dynamic boundary curve for each of the plurality of moving windows. The method further includes controlling a drilling operation based at least in part on the high-resolution lithology model.