公开(公告)号：US6070971A

公开(公告)日：2000-06-06

申请号：US932259

申请日：1997-09-22

申请人： Minoru Usui ,  Takahiro Katakura ,  Munehide Kanaya ,  Motonori Okumura ,  Tomohiro Yamada ,  Shinsuke Yano

发明人： Minoru Usui ,  Takahiro Katakura ,  Munehide Kanaya ,  Motonori Okumura ,  Tomohiro Yamada ,  Shinsuke Yano

IPC分类号： B41J2/045 ,  B41J2/055 ,  B41J2/14 ,  B41J2/16 ,  H01L41/09

CPC分类号： B41J2/1637 ,  B41J2/14233 ,  B41J2/161 ,  B41J2/1634

摘要： An actuator for an ink jet printer includes: an ink tank comprising a thick substrate having a cavity structure and a vibrating plate covering a cavity; and a piezoelectric/electrostrictive working portion comprising an upper electrode layer, a lower electrode layer, and a piezoelectric/electrostrictive layer between the electrode layers, the piezoelectric/electrostrictive working portion being disposed on the ink tank so that the lower electrode layer contacts with the vibrating plate. The upper electrode is trimmed only in the portion where the piezoelectric/electro-strictive layer covers the vibrating plate so as to control an effective electrode area and adjust an ink jet volume to be appropriate. The upper electrode layer is trimmed with the piezoelectric/electrostrictive layer covering the vibrating plate at least near the portion to be trimmed of the upper electrode layer so as to control an effective electrode area and adjust an ink jet volume.

摘要翻译： 用于喷墨打印机的致动器包括：墨盒，包括具有空腔结构的厚基底和覆盖空腔的振动板; 以及包括在电极层之间的上电极层，下电极层和压电/电致伸缩层的压电/电致伸缩工作部分，压电/电致伸缩工作部分设置在墨罐上，使得下电极层与 振动板 仅在压电/电绝缘层覆盖振动板的部分中修整上电极，以便控制有效电极面积并调整喷墨量是合适的。 上电极层用压电/电致伸缩层进行修整，该压电/电致伸缩层至少在上电极层的修剪部分附近覆盖振动板，以便控制有效电极面积并调节喷墨体积。

公开(公告)号：US6076244A

公开(公告)日：2000-06-20

申请号：US190464

申请日：1998-11-12

申请人： Motonori Okumura ,  Takaichi Wada ,  Tadao Furuta ,  Shinsuke Yano ,  Tomohiro Yamada ,  Nobuo Takahashi

发明人： Motonori Okumura ,  Takaichi Wada ,  Tadao Furuta ,  Shinsuke Yano ,  Tomohiro Yamada ,  Nobuo Takahashi

IPC分类号： B41J2/045 ,  B41J2/055 ,  B41J2/16 ,  H01L41/09 ,  H04R17/08 ,  H04R17/00 ,  B32B31/14

CPC分类号： B41J2/1632 ,  B41J2/161 ,  B41J2/1623 ,  B41J2002/14387 ,  H04R17/08 ,  Y10T29/42 ,  Y10T29/49401

摘要： A method of manufacturing an actuator including an ink pump section made by forming a spacer plate with a plurality of window portions formed therein, a closure plate stacked on one side of the spacer plate for covering the window portions and a connection plate stacked on the other side of the spacer plate for covering the above window portions. These plates are formed as laminated ceramic green sheets that are later fired to form an integrated body. A piezoelectric/electrostrictive operating section composed of electrodes and a piezoelectric/electrostrictive layer is then formed on the outer surface of the closure plate. Thereafter, the actuator is pasted to a holding adhesive film and the holding adhesive film is stripped from the actuator after subjecting the actuator to a given inspection, if necessary, or to cutting into a given shape, if necessary. Subsequently, the actuator is heat-treated. Then, onto this actuator, an ink nozzle member with a plurality of nozzle holes is stacked and joined. The ink jet print head has a strong adhesive joint between the actuator and the ink nozzle member and improved liquid resistance.

摘要翻译： 一种制造致动器的方法，该致动器包括通过形成具有形成在其中的多个窗口部分的间隔板而形成的墨泵部分，堆叠在用于覆盖窗口部分的间隔板的一侧上的封闭板和彼此堆叠的连接板 隔离板的一侧用于覆盖上述窗口部分。 这些板形成为稍后烧制以形成一体的层叠陶瓷生片。 然后在封闭板的外表面上形成由电极和压电/电致伸缩层组成的压电/电致伸缩操作部分。 此后，如果需要，将致动器粘贴到保持粘合剂膜上，并且在必要时对执行器进行给定的检查之后，或者如果需要切割成给定的形状，将保持粘合剂膜从致动器剥离。 随后，对致动器进行热处理。 然后，在该致动器上，堆叠并接合具有多个喷嘴孔的墨水喷嘴构件。 喷墨打印头在致动器和墨水喷嘴构件之间具有强的粘合剂接合并且具有改善的液体阻力。

公开(公告)号：US08877519B2

公开(公告)日：2014-11-04

申请号：US12738228

申请日：2008-10-29

申请人： Tomohiro Yamada ,  Yoichiro Handa

发明人： Tomohiro Yamada ,  Yoichiro Handa

IPC分类号： G01N33/553 ,  G01N21/55 ,  G01N21/27

CPC分类号： G01N21/554 ,  G01N21/27 ,  Y10S436/805

摘要： A chemical sensor element contains a resonator having a first reflector in which particles of a fine metal structure are arranged two-dimensionally and periodically is counterposed with interposition of a dielectric layer to a second reflector, wherein the resonance wavelength of a resonator in which the entire of the first reflector is replaced by a metal thin film having the same thickness as the metal fine structure is different from the surface plasmon resonance wavelength induced in the metal fine structure; and the mode of the surface plasmon resonance excited in the metal fine structure is coupled with the mode of the resonator in which the entire of the first reflector is replaced by the metal thin film.

摘要翻译： 化学传感器元件包括具有第一反射器的谐振器，其中精细金属结构的颗粒被二维地周期性布置，并且与第二反射器插入电介质层，其中整个谐振器的谐振波长 由具有与金属精细结构相同的厚度的金属薄膜替换为与金属精细结构中诱发的表面等离子体共振波长不同的金属薄膜; 并且在金属精细结构中激发的表面等离子体激元谐振的模式与谐振器的模式耦合，其中整个第一反射器被金属薄膜代替。

公开(公告)号：US08570464B2

公开(公告)日：2013-10-29

申请号：US12824067

申请日：2010-06-25

申请人： Tomohiro Yamada ,  Ryo Kuroda

发明人： Tomohiro Yamada ,  Ryo Kuroda

IPC分类号： G02F1/1335 ,  G02B5/22

CPC分类号： G02B5/1809 ,  G02B5/203

摘要： An optical filter includes a substrate, and a periodic structure in which a plurality of members formed of silicon are periodically arranged on a surface of the substrate. The filter selectively transmits light of a first wavelength included in light incident on the periodic structure in the direction of the substrate. The members are two-dimensionally arranged with a period of 400 nm to 500 nm. The dimension of the members in the direction parallel to the surface is of 120 nm to 160 nm. A local maximum value of the transmission spectrum of the first wavelength is within the range of 400 nm to 500 nm.

摘要翻译： 光学滤波器包括衬底，并且周期性结构，其中由硅形成的多个构件周期性地布置在衬底的表面上。 滤光器选择性地透射入射在周期性结构上的光在基板的方向上包括的第一波长的光。 构件以400nm至500nm的周期二维排列。 构件在平行于表面的方向上的尺寸为120nm至160nm。 第一波长的透射光谱的局部最大值在400nm至500nm的范围内。

公开(公告)号：US20130197009A1

公开(公告)日：2013-08-01

申请号：US13877358

申请日：2011-10-21

申请人： Yukitaka Ideyama ,  Sadao Kuromitsu ,  Takashi Furutani ,  Masayoshi Takeda ,  Satoshi Konagai ,  Tomohiro Yamada ,  Nobuaki Taniguchi ,  Yutaka Kondoh ,  Masaaki Hirano ,  Kazushi Watanabe ,  Takashi Sugane ,  Akio Kakefuda

发明人： Yukitaka Ideyama ,  Sadao Kuromitsu ,  Takashi Furutani ,  Masayoshi Takeda ,  Satoshi Konagai ,  Tomohiro Yamada ,  Nobuaki Taniguchi ,  Yutaka Kondoh ,  Masaaki Hirano ,  Kazushi Watanabe ,  Takashi Sugane ,  Akio Kakefuda

IPC分类号： C07D401/02 ,  C07D401/14 ,  C07D403/02

CPC分类号： C07D401/02 ,  A61K31/496 ,  A61K31/506 ,  C07D401/12 ,  C07D401/14 ,  C07D403/02 ,  C07D403/12

摘要： [Problem] An object of the present invention is to provide a novel anticancer drug which is useful for treating prostate cancer accompanying androgen receptor mutation[Means for Solution] The present inventors conducted thorough research on mutant androgen-related diseases for which the traditional anti-androgen drugs become ineffective. As a result, they found that the compound, which is an active ingredient of the pharmaceutical composition of the present invention, exhibits an inhibitory action against transcriptional activation in a human mutant androgen receptor (AR), and has an excellent antitumor action in a human prostate cancer-bearing mouse, thereby completing the present invention. Accordingly, the compound, which is an active ingredient of the pharmaceutical composition of the present invention, is useful for a series of androgen receptor-related diseases including prostate cancer.

摘要翻译： 本发明的目的在于提供一种可用于治疗伴随雄激素受体突变的前列腺癌的新型抗癌药物。本发明人进行了关于雄激素相关疾病的全面研究， 雄激素药物变得无效。 结果发现，作为本发明的药物组合物的活性成分的化合物在人突变型雄激素受体（AR）中表现出对转录活化的抑制作用，并且在人体中具有优异的抗肿瘤作用 前列腺癌的小鼠，从而完成本发明。 因此，作为本发明的药物组合物的活性成分的化合物可用于一系列与前列腺癌有关的雄激素受体相关疾病。

公开(公告)号：US08368898B2

公开(公告)日：2013-02-05

申请号：US12852808

申请日：2010-08-09

申请人： Tomohiro Yamada

发明人： Tomohiro Yamada

IPC分类号： G01N21/55 ,  G02B5/26

CPC分类号： G02B5/008 ,  B82Y20/00 ,  G02B6/1226 ,  G02B6/3624

摘要： Provided is an optical apparatus having high durability, less optical absorption than a hole-type metal thin film filter, high transmittance and high reflectance, and variable optical characteristics. The apparatus includes: a dielectric substrate; a metal structure group including multiple metal structures two-dimensionally and discretely disposed at regular intervals; and a dielectric layer covering the metal structure group, in which: the metal structures have a first length equal to or shorter than a predetermined wavelength in a visible light region in one direction, and a second length equal to or shorter than the wavelength in a perpendicular direction; and the metal structures resonates with light entering the dielectric substrate or the dielectric layer, having a variable dielectric constant, to generate localized surface plasmon resonance on a surface of the metal structures to have a minimum transmittance or a maximum reflectance of the light having the wavelength.

摘要翻译： 提供一种具有高耐久性，比空穴型金属薄膜滤光器的光吸收性低，透光率高，反射率高，光学特性可变的光学装置。 该装置包括：电介质基片; 包括以规则间隔二维和离散地设置的多个金属结构的金属结构组; 以及覆盖所述金属结构体的介电层，其中：所述金属结构具有在一个方向上的可见光区域中等于或短于预定波长的第一长度，以及等于或短于一个方向上的波长的第二长度 垂直方向 并且金属结构与进入具有可变介电常数的电介质基板或电介质层的光谐振，以在金属结构的表面上产生局部表面等离子体共振，以具有波长最小的光的最小透射率或最大反射率 。

公开(公告)号：US08321573B2

公开(公告)日：2012-11-27

申请号：US11663068

申请日：2005-09-01

申请人： Keiji Hirao ,  Motoe Sakanaka ,  Tomohiro Yamada

发明人： Keiji Hirao ,  Motoe Sakanaka ,  Tomohiro Yamada

IPC分类号： G06F15/16

CPC分类号： H04M11/007 ,  H04L41/08 ,  H04L41/0806 ,  H04L41/0886 ,  H04M1/72533

摘要： A communication terminal includes a CPU (28). The CPU (28) issues to a router (16) a send request for requesting the router (16) to send an ask signal for repetitive responses to a server (14). Then, the ask signal is sent to the server (14) by the router (16), and a receive port is temporarily opened. From the server (14), a response signal is repeatedly sent in response to the ask signal. To the response signal, time information representative of a waiting time from receiving an ask signal to its reply is attached. A response signal sent back while the receive port is opened arrives at the communication terminal through the router (16), but a response signal sent back after the receive port is closed is discarded in the router (16). The CPU (28) repeatedly issues a send request to the router (16) regarding a time indicated by time information attached to the response signal lastly received as an issuance cycle (T).

摘要翻译： 通信终端包括CPU（28）。 CPU（28）向路由器（16）发出请求路由器（16）向服务器（14）发送重复响应的询问信号的发送请求。 然后，询问信号被路由器（16）发送到服务器（14），并且接收端口被暂时打开。 从服务器（14），响应于询问信号重复地发送响应信号。 对于响应信号，附加表示从接收询问信号到其答复的等待时间的时间信息。 在接收端口打开时发回的响应信号通过路由器（16）到达通信终端，但在接收端口关闭后发回的响应信号在路由器（16）中被丢弃。 CPU（28）重复向路由器（16）发出关于由附加到最后接收的作为发行周期（T）的响应信号的时间信息指示的时间的发送请求。

公开(公告)号：US08154722B2

公开(公告)日：2012-04-10

申请号：US11677890

申请日：2007-02-22

申请人： Tomohiro Yamada ,  Yoichiro Handa

发明人： Tomohiro Yamada ,  Yoichiro Handa

IPC分类号： G01J3/44

CPC分类号： G01N21/554 ,  G01N2021/258

摘要： Even when only a few antigens exist in a specimen, a change in a dielectric constant and a change in an optical spectrum accompanied thereto in the periphery of a conductive member are made larger, so that sensing at high sensitivity can be performed. A structure including a protrusion including a dielectric material protruded on a substrate and a conductive member provided on a first surface of the protrusion, in which the maximum value of the cross-sectional area in the cross-section in parallel with a first surface of the conductive member is larger than the area of the first surface.

摘要翻译： 即使在试样中只存在少量抗原，导电性部件的周围的介电常数的变化和伴随其的光谱的变化也变大，可以进行高灵敏度的感测。 一种结构，其特征在于，具有包括突出在基板上的介电材料的突起和设置在所述突起的第一面上的导电性部件，所述突起的横截面积的最大值与所述突起的第一面平行的截面积的最大值 导电构件比第一表面的面积大。

公开(公告)号：US20120026504A1

公开(公告)日：2012-02-02

申请号：US13192921

申请日：2011-07-28

申请人： Tomohiro Yamada

发明人： Tomohiro Yamada

IPC分类号： G01B9/02 ,  H01S3/113 ,  H01S3/10

CPC分类号： G01B9/02091 ,  G01B9/02004 ,  H01S3/06791 ,  H01S3/08004 ,  H01S3/08059 ,  H01S3/10084 ,  H01S3/113 ,  H01S5/50 ,  H01S2301/04

摘要： A light source apparatus includes an optical resonator formed by an optical amplification medium and an optical switch. The optical switch includes a saturable absorber and changes its transmittance or reflectance when receiving an optical pulse emitted from a light irradiation source which includes a wavelength-tunable light source. The light source apparatus emits amplified light from the optical resonator in correspondence with the center wavelength of the optical pulse from the wavelength-tunable light source. The relationship between a length L and an effective refractive index n of the optical resonator and a repetition frequency f of the optical pulse satisfies a condition L (nL)/c.

摘要翻译： 光源装置包括由光放大介质和光开关构成的光谐振器。 光学开关包括可饱和吸收体，并在接收到包括波长可调光源的光照射源发射的光脉冲时，改变其透射率或反射率。 光源装置对应于来自波长可调光源的光脉冲的中心波长，从光谐振器发射放大的光。 光谐振器的长度L和有效折射率n之间的关系以及光脉冲的重复频率f满足条件L （nL）/ c。

公开(公告)号：US20110304853A1

公开(公告)日：2011-12-15

申请号：US13154127

申请日：2011-06-06

申请人： Tomohiro Yamada ,  Kentaro Furusawa

发明人： Tomohiro Yamada ,  Kentaro Furusawa

IPC分类号： G01B9/02 ,  H01S3/10

CPC分类号： G01B9/02007 ,  G01B9/02004 ,  G01B9/02027 ,  G01B9/02091 ,  H01S3/08013 ,  H01S3/083 ,  H01S3/10046 ,  H01S5/0085 ,  H01S5/0656 ,  H01S5/0657 ,  H01S5/06835 ,  H01S5/14 ,  H01S5/4012 ,  H01S5/4087

摘要： A light source apparatus includes a laser oscillator equipped with a first optical resonator, a plurality of second optical resonators including input portions respectively connected in parallel to the first optical resonator, a plurality of light extraction units configured to extract a light beam from an output portion of each second optical resonator, and a light multiplexing unit configured to multiplex the light beam extracted from each light extraction unit, wherein the light source apparatus causes the light multiplexing unit to output a multiplexed light beam passed through the plurality of second optical resonators, an optical member having refractive index dispersion and an optical amplification medium are disposed in each of the plurality of second optical resonators, and the optical amplification media of the plurality of second optical resonators are different from each other in maximum gain wavelength.

摘要翻译： 光源装置包括配备有第一光谐振器的激光振荡器，包括分别并联连接到第一光谐振器的输入部分的多个第二光谐振器，多个光提取单元，被配置为从输出部分 以及光复用单元，其被配置为对从每个光提取单元提取的光束进行多路复用，其中所述光源装置使所述光复用单元输出通过所述多个第二光谐振器的复用光束， 具有折射率色散的光学构件和光学放大介质设置在多个第二光学谐振器中的每一个中，多个第二光学谐振器的光学放大介质在最大增益波长方面彼此不同。