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公开(公告)号：US20250057954A1
公开(公告)日：2025-02-20
申请号：US18821057
申请日：2024-08-30
Applicant: ModernaTX, Inc.
Inventor： Antonin DE FOUGEROLLES , Sayda M. ELBASHIR
IPC: A61K47/18 , A61K31/7088 , A61K31/7115 , A61K38/19 , A61K38/48 , A61K47/22 , A61K47/28 , A61K48/00 , C07K14/535 , C12N9/64 , C12N15/67 , C12N15/87
Abstract: Provided are formulations, compositions and methods for delivering biological moieties such as modified nucleic acids into cells to modulate protein expression. Such compositions and methods include the delivery of biological moieties, and are useful for production of proteins.
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公开(公告)号：US20210386857A1
公开(公告)日：2021-12-16
申请号：US17141753
申请日：2021-01-05
Applicant: ModernaTX, Inc.
Inventor： Antonin DE FOUGEROLLES , Sayda M. ELBASHIR
IPC: A61K47/18 , A61K31/7088 , C12N15/87 , A61K31/7115 , C12N15/67 , C07K14/535 , C12N9/64 , A61K38/19 , A61K38/48 , A61K47/22 , A61K47/28
Abstract: Provided are formulations, compositions and methods for delivering biological moieties such as modified nucleic acids into cells to modulate protein expression. Such compositions and methods include the delivery of biological moieties, and are useful for production of proteins.
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公开(公告)号：US20200164038A1
公开(公告)日：2020-05-28
申请号：US16525145
申请日：2019-07-29
Applicant: ModernaTX, Inc.
Inventor： Antonin DE FOUGEROLLES , Kristy M. WOOD , Sayda M. ELBASHIR , Noubar B. AFEYAN , Pedro VALENCIA , Jason P. SCHRUM
IPC: A61K38/19 , C07K14/535 , A61K31/7105 , C12N15/117 , A61K48/00 , C12P21/00 , A61K31/7088 , C07K2/00 , C12N15/88 , A61K9/16 , A61K9/127 , A61K9/00 , C12N15/00 , A61K38/48 , A61K9/14
Abstract: The present disclosure provides, inter alia, formulation compositions comprising modified nucleic acid molecules which may encode a protein, a protein precursor, or a partially or fully processed form of the protein or a protein precursor. The formulation composition may further include a modified nucleic acid molecule and a delivery agent. The present invention further provides nucleic acids useful for encoding polypeptides capable of modulating a cell's function and/or activity.
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公开(公告)号：US20180125937A1
公开(公告)日：2018-05-10
申请号：US15621693
申请日：2017-06-13
Applicant: ModernaTX, Inc.
Inventor： Antonin DE FOUGEROLLES , Kristy M. WOOD , Sayda M. ELBASHIR , Noubar B. AFEYAN , Pedro VALENCIA , Jason P. SCHRUM
IPC: A61K38/19 , C12N15/00 , C12P21/00 , A61K9/14 , A61K9/127 , A61K38/48 , A61K48/00 , C07K14/535 , A61K31/7105 , A61K9/16 , A61K9/00 , A61K31/7088 , C07K2/00 , C12N15/117 , C12N15/88
CPC classification number: A61K38/193 , A61K9/0019 , A61K9/0024 , A61K9/0048 , A61K9/1271 , A61K9/1272 , A61K9/14 , A61K9/16 , A61K9/1647 , A61K31/7088 , A61K31/7105 , A61K38/4833 , A61K48/00 , A61K48/0033 , A61K48/0041 , A61K48/005 , A61K48/0066 , C07K2/00 , C07K14/535 , C12N15/00 , C12N15/117 , C12N15/88 , C12P21/00
Abstract: The present disclosure provides, inter alia, formulation compositions comprising modified nucleic acid molecules which may encode a protein, a protein precursor, or a partially or fully processed form of the protein or a protein precursor. The formulation composition may further include a modified nucleic acid molecule and a delivery agent. The present invention further provides nucleic acids useful for encoding polypeptides capable of modulating a cell's function and/or activity.
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公开(公告)号：US20250064937A1
公开(公告)日：2025-02-27
申请号：US18821068
申请日：2024-08-30
Applicant: ModernaTX, Inc.
Inventor： Antonin DE FOUGEROLLES , Sayda M. ELBASHIR
IPC: A61K47/18 , A61K31/7088 , A61K31/7115 , A61K38/19 , A61K38/48 , A61K47/22 , A61K47/28 , A61K48/00 , C07K14/535 , C12N9/64 , C12N15/67 , C12N15/87
Abstract: Provided are formulations, compositions and methods for delivering biological moieties such as modified nucleic acids into cells to modulate protein expression. Such compositions and methods include the delivery of biological moieties, and are useful for production of proteins.
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Patent Agency Ranking
6.发明申请公开(公告)号：US20210299278A1
公开(公告)日：2021-09-30
申请号：US17020522
申请日：2020-09-14
Applicant: ModernaTX, Inc.
Inventor： Stephane BANCEL , Tirtha CHAKRABORTY , Antonin DE FOUGEROLLES , Sayda M. ELBASHIR , Matthias JOHN , Atanu ROY , Susan WHORISKEY , Kristy M. WOOD , Paul HATALA , Jason P. SCHRUM , Kenechi EJEBE , Jeff Lynn ELLSWORTH , Justin GUILD
IPC: A61K48/00 , C12N15/85 , C07K14/47 , C07K14/62 , A61K31/7115 , C12N9/88 , A61K9/127 , C12N15/11 , C07K14/705 , C07K14/505 , C07K14/535 , C12N9/64 , C12N9/10 , C12N9/00 , C12N9/42 , C12N15/87 , C12P13/04 , A61K38/45 , C07K14/005 , C12N9/16 , C12N9/24 , C12N15/52 , A61K38/17 , C07K14/435 , C12P21/00 , C07K14/485 , C07H21/02 , C07K14/475 , C07K14/495 , C07K14/525 , C07K14/54 , C07K14/56 , C07K14/61 , C07K14/745 , C07K16/28 , C07K16/40 , C12N9/02 , C12N9/12 , C12N9/68 , A61K47/54 , A61K9/14 , A61K9/51 , A61K38/18 , A61K38/19 , A61K38/21 , A61K38/48 , C07K14/515 , C07K16/00
Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules.
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公开(公告)号：US20170368200A1
公开(公告)日：2017-12-28
申请号：US15425645
申请日：2017-02-06
Applicant: ModernaTX, Inc.
Inventor： Stephane BANCEL , Tirtha CHAKRABORTY , Antonin DE FOUGEROLLES , Sayda M. ELBASHIR , Matthias JOHN , Atanu ROY , Susan WHORISKEY , Kristy M. WOOD , Paul HATALA , Jason P. SCHRUM , Kenechi EJEBE , Jeff Lynn ELLSWORTH , Justin GUILD
IPC: A61K48/00 , A61K9/127 , C12P21/00 , C12P13/04 , C12N15/87 , C12N15/85 , C12N15/52 , C12N15/11 , C12N9/00 , C12N9/88 , C12N9/64 , C12N9/42 , C12N9/24 , C12N9/16 , C12N9/10 , C07K16/00 , C07K14/705 , C07K14/62 , C07K14/56 , C07K14/535 , C07K14/525 , C07K14/515 , C07K14/505 , A61K47/54 , C07K14/47 , C07K14/435 , C07K14/005 , A61K38/48 , A61K38/45 , A61K38/21 , A61K38/19 , A61K38/18 , A61K38/17 , A61K31/7115 , A61K9/51 , A61K9/14 , C07K14/485 , A61K38/00
Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules.
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公开(公告)号：US20250090667A1
公开(公告)日：2025-03-20
申请号：US18820652
申请日：2024-08-30
Applicant: ModernaTX, Inc.
Inventor： Antonin DE FOUGEROLLES , Sayda M. ELBASHIR
IPC: A61K47/18 , A61K31/7088 , A61K31/7115 , A61K38/19 , A61K38/48 , A61K47/22 , A61K47/28 , A61K48/00 , C07K14/535 , C12N9/64 , C12N15/67 , C12N15/87
Abstract: Provided are formulations, compositions and methods for delivering biological moieties such as modified nucleic acids into cells to modulate protein expression. Such compositions and methods include the delivery of biological moieties, and are useful for production of proteins.
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公开(公告)号：US20250090666A1
公开(公告)日：2025-03-20
申请号：US18820609
申请日：2024-08-30
Applicant: ModernaTX, Inc.
Inventor： Antonin DE FOUGEROLLES , Sayda M. ELBASHIR
IPC: A61K47/18 , A61K31/7088 , A61K31/7115 , A61K38/19 , A61K38/48 , A61K47/22 , A61K47/28 , A61K48/00 , C07K14/535 , C12N9/64 , C12N15/67 , C12N15/87
Abstract: Provided are formulations, compositions and methods for delivering biological moieties such as modified nucleic acids into cells to modulate protein expression. Such compositions and methods include the delivery of biological moieties, and are useful for production of proteins.
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公开(公告)号：US20210115101A1
公开(公告)日：2021-04-22
申请号：US16665985
申请日：2019-10-28
Applicant: ModernaTX, Inc.
Inventor： Stephane BANCEL , Tirtha CHAKRABORTY , Antonin DE FOUGEROLLES , Sayda M. ELBASHIR , Matthias JOHN , Atanu ROY , Susan WHORISKEY , Kristy M. WOOD , Paul HATALA , Jason P. SCHRUM , Kenechi EJEBE , Jeff Lynn ELLSWORTH , Justin GUILD
IPC: C07K14/535 , A61K48/00 , A61K47/54 , C12N15/88 , A61K9/127 , A61K9/50 , C07K14/47 , A61K31/7088 , C07K19/00 , C12N15/85 , A61K38/18 , A61K38/19 , A61K38/48 , A61K9/14 , A61K38/17 , A61K47/10 , A61K38/21 , A61K38/36 , A61K38/44 , A61K39/395 , C07K14/475 , C07K14/505 , C07K14/525 , C07K14/56 , C07K14/565 , C07K14/745 , C07K14/75 , C07K16/28 , C07K16/32 , C12N9/02 , C12N9/64
Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules.
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