专利检索 ap:("ModernaTX, Inc.") AND inv:"Atanu ROY" 第 1 页

1.

发明申请
ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF 审中-公开

公开(公告)号：US20190255194A1

公开(公告)日：2019-08-22

申请号：US16289947

申请日：2019-03-01

申请人： ModernaTX, Inc.

发明人： Atanu ROY , Christopher R. CONLEE , Antonin DE FOUGEROLLES , Andrew W. FRALEY , Gabor BUTORA , Matthew STANTON

IPC分类号： A61K48/00 , C12N15/87 , C07D498/22 , C07H19/06 , C12N15/11 , C07D487/16 , C07D487/04 , C07D473/40 , C07D473/38 , C07D473/34 , C07D473/30 , C07D473/18 , C07D473/16 , C07H19/23 , C07H19/20 , C07H19/167 , C07H19/14 , C07H19/10 , C07H19/067 , C07D239/54 , C07D405/04 , C07F9/6561 , C07F9/6558 , C07H19/16 , C12N15/67 , C07H21/02

摘要： The present disclosure provides alternative nucleosides, nucleotides, and nucleic acids, and methods of using them.

2.

发明申请
MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF PROTEINS ASSOCIATED WITH HUMAN DISEASE 有权

公开(公告)号：US20210115101A1

公开(公告)日：2021-04-22

申请号：US16665985

申请日：2019-10-28

申请人： ModernaTX, Inc.

发明人： Stephane BANCEL , Tirtha CHAKRABORTY , Antonin DE FOUGEROLLES , Sayda M. ELBASHIR , Matthias JOHN , Atanu ROY , Susan WHORISKEY , Kristy M. WOOD , Paul HATALA , Jason P. SCHRUM , Kenechi EJEBE , Jeff Lynn ELLSWORTH , Justin GUILD

IPC分类号： C07K14/535 , A61K48/00 , A61K47/54 , C12N15/88 , A61K9/127 , A61K9/50 , C07K14/47 , A61K31/7088 , C07K19/00 , C12N15/85 , A61K38/18 , A61K38/19 , A61K38/48 , A61K9/14 , A61K38/17 , A61K47/10 , A61K38/21 , A61K38/36 , A61K38/44 , A61K39/395 , C07K14/475 , C07K14/505 , C07K14/525 , C07K14/56 , C07K14/565 , C07K14/745 , C07K14/75 , C07K16/28 , C07K16/32 , C12N9/02 , C12N9/64

摘要： The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules.

3.

发明申请
MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF BIOLOGICS AND PROTEINS ASSOCIATED WITH HUMAN DISEASE 审中-公开

公开(公告)号：US20180311381A1

公开(公告)日：2018-11-01

申请号：US15790246

申请日：2017-10-23

申请人： ModernaTX, Inc.

发明人： Stephane BANCEL , Tirtha CHAKRABORTY , Antonin DE FOUGEROLLES , Sayda M. ELBASHIR , Matthias JOHN , Atanu ROY , Susan WHORISKEY , Kristy M. WOOD , Paul HATALA , Jason P. SCHRUM , Kenechi EJEBE , Jeff Lynn ELLSWORTH , Justin GUILD

IPC分类号： A61K48/00 , C12P21/00 , C12P13/04 , C12N15/87 , C12N15/85 , C12N15/52 , C12N15/11 , C12N9/00 , C12N9/88 , C12N9/64 , C12N9/68 , C12N9/42 , C12N9/24 , C12N9/16 , C12N9/12 , C12N9/10 , C12N9/02 , C07K16/40 , C07K16/28 , C07K16/00 , C07K14/745 , C07K14/705 , C07K14/62 , C07K14/61 , C07K14/56 , C07K14/54 , C07K14/535 , C07K14/525 , C07K14/515 , C07K14/505 , C07K14/495 , C07K14/485 , C07K14/475 , C07K14/47 , C07K14/435 , C07K14/005 , C07H21/02 , A61K38/48 , A61K38/45 , A61K38/21 , A61K38/19 , A61K38/18 , A61K38/17 , A61K31/7115 , A61K9/51 , A61K9/14 , A61K9/127 , A61K47/54 , A61K38/00

摘要： The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules.

4.

发明申请
MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF NUCLEAR PROTEINS 审中-公开

公开(公告)号：US20180170990A1

公开(公告)日：2018-06-21

申请号：US15662090

申请日：2017-07-27

申请人： ModernaTX, Inc.

发明人： Stephane BANCEL , Tirtha CHAKRABORTY , Antonin DE FOUGEROLLES , Sayda M. ELBASHIR , Matthias JOHN , Atanu ROY , Susan WHORISKEY , Paul HATALA , Jason P. SCHRUM , Kenechi EJEBE , Jeff Lynn ELLSWORTH , Justin GUILD , Ron WEISS , Kristy M. WOOD

IPC分类号： C07K14/535 , A61K48/00 , C07K14/745 , C07K16/28 , C07K16/32 , C12N9/02 , C12N9/64 , A61K38/19 , A61K38/21 , A61K38/36 , A61K38/44 , A61K38/48 , A61K39/395 , C07K14/475 , C07K14/505 , C07K14/525 , C07K14/56 , C07K14/565 , C07K14/75 , A61K47/10 , A61K38/18 , A61K38/17 , A61K9/14 , C07K14/47 , C12N15/85 , A61K9/50 , A61K9/127

CPC分类号： C07K14/535 , A61K9/0019 , A61K9/1271 , A61K9/1272 , A61K9/1277 , A61K9/14 , A61K9/5031 , A61K31/7088 , A61K38/1767 , A61K38/1816 , A61K38/1866 , A61K38/191 , A61K38/193 , A61K38/212 , A61K38/215 , A61K38/36 , A61K38/363 , A61K38/44 , A61K38/4833 , A61K38/4846 , A61K39/3955 , A61K47/10 , A61K47/54 , A61K47/542 , A61K48/00 , A61K48/0033 , A61K48/0066 , A61K48/0075 , C07K14/47 , C07K14/475 , C07K14/505 , C07K14/525 , C07K14/56 , C07K14/565 , C07K14/745 , C07K14/75 , C07K16/2887 , C07K16/32 , C07K19/00 , C12N9/0069 , C12N9/644 , C12N15/85 , C12N15/88 , C12N2840/00 , C12Y113/12007 , C12Y304/21005 , C12Y304/21022

摘要： The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules.

5.

发明申请
MODIFIED NUCLEOSIDES, NUCLEOTIDES, AND NUCLEIC ACIDS, AND USES THEREOF 有权

公开(公告)号：US20210308283A1

公开(公告)日：2021-10-07

申请号：US17032657

申请日：2020-09-25

申请人： ModernaTX, Inc.

发明人： Antonin DE FOUGEROLLES , Atanu ROY

IPC分类号： A61K48/00 , C12N15/67 , C12N15/11 , C07H21/02 , A61K38/19 , C07K14/535

摘要： The present disclosure provides modified nucleosides, nucleotides, and nucleic acids, and methods of using them.

6.

发明申请
TERMINALLY MODIFIED RNA 审中-公开

公开(公告)号：US20190290742A1

公开(公告)日：2019-09-26

申请号：US16152945

申请日：2018-10-05

申请人： ModernaTX, Inc.

发明人： Tirtha CHAKRABORTY , Stephane BANCEL , Stephen G. HOGE , Atanu ROY , Antonin DE FOUGEROLLES , Noubar B. AFEYAN

IPC分类号： A61K39/00 , C12N15/67

摘要： The invention relates to compositions and methods for the manufacture and optimization of modified mRNA molecules via optimization of their terminal architecture.

7.

发明申请
TERMINALLY MODIFIED RNA 有权

公开(公告)号：US20220395562A1

公开(公告)日：2022-12-15

申请号：US17127435

申请日：2020-12-18

申请人： ModernaTX, Inc.

发明人： Tirtha CHAKRABORTY , Stephane BANCEL , Stephen G. HOGE , Atanu ROY , Antonin DE FOUGEROLLES , Noubar B. AFEYAN

IPC分类号： A61K39/00 , C12N15/67

摘要： The invention relates to compositions and methods for the manufacture and optimization of modified mRNA molecules via optimization of their terminal architecture.