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    Oral film-form base and preparation
    3.
    发明授权
    Oral film-form base and preparation 有权

    公开(公告)号：US10092505B2

    公开(公告)日：2018-10-09

    申请号：US13737255

    申请日：2013-01-09

    Applicant: NITTO DENKO CORPORATION

    Inventor： Daisuke Asari ,  Mitsuhiko Hori ,  Takuya Shishido

    IPC: A61K9/46 ,  A61K9/00 ,  A61K47/02

    Abstract: The present invention provides an oral film-form base which has a rapid dissolution profile in the mouth and sufficient film strength, and gives an improved taking property by foaming in the mouth. The oral film-form base includes an edible polymer soluble both in water and in an organic solvent having a solubility parameter of 9.7 or higher, a foaming agent, and an auxiliary foaming agent, wherein the foaming agent is foamable in the presence of water, and the foaming agent and the auxiliary foaming agent each are insoluble in the organic solvent, have an average particle size of 0.1 to 60 μm, and are included in particle states.

    Allergy vaccine composition
    9.
    发明授权
    Allergy vaccine composition 有权

    公开(公告)号：US10688120B2

    公开(公告)日：2020-06-23

    申请号：US15570851

    申请日：2016-04-28

    Applicant: NITTO DENKO CORPORATION

    Inventor： Kyohei Matsushita ,  Masahiro Fukasaka ,  Takuya Shishido ,  Daisuke Asari ,  Katsuyuki Okubo ,  Mitsuhiko Hori

    IPC: A61K31/739 ,  A61K39/39 ,  A61K39/00 ,  A61K39/02 ,  A61K39/35 ,  A61P37/02 ,  A61P37/08 ,  A61P11/02 ,  A61P11/06

    Abstract: The present invention provides an allergy vaccine composition that is useful as a prophylactic or therapeutic agent for an allergic disease and can safely and effectively induce immune tolerance. The vaccine composition is to be administered to a human or animal with an allergic disease for the prevention or treatment of the allergic disease. The vaccine composition contains: an immunomodulator which is a lipopolysaccharide derived from at least one gram-negative bacterium selected from the group consisting of Serratia, Leclercia, Rahnella, Acidicaldus, Acidiphilium, Acidisphaera, Acidocella, Acidomonas, Asaia, Belnapia, Craurococcus, Gluconacetobacter, Gluconobacter, Kozakia, Leahibacter, Muricoccus, Neoasaia, Oleomonas, Paracraurococcus, Rhodopila, Roseococcus, Rubritepida, Saccharibacter, Stella, Swaminathania, Teichococcus, Zavarzinia, Pseudomonas, Achromobacter, Bacillus, Methanoculleus, Methanosarcina, Clostridium, Micrococcus, Flavobacterium, Pantoea, Acetobacter, Zymomonas, Xanthomonas, and Enterobacter, or a salt of the lipopolysaccharide; and at least one allergen.

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