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1.发明申请INTRINSIC FREQUENCY ANALYSIS FOR LEFT VENTRICLE EJECTION FRACTION OR STROKE VOLUME DETERMINATION 有权用于左心室射血分数或排气量测定的内在频率分析公开(公告)号：US20150112219A1
公开(公告)日：2015-04-23
申请号：US14517702
申请日：2014-10-17
CPC分类号： A61B5/1128 , A61B5/0004 , A61B5/0013 , A61B5/02028 , A61B5/021 , A61B5/02405 , A61B5/0261 , A61B5/029 , A61B5/1102 , A61B5/7235 , A61B5/7278 , A61B5/7282 , A61B8/065 , A61B8/5223 , A61B2562/0228
摘要： Hardware and software methodology are described for non-invasively monitoring cardiac health. Hemodynamic waveforms variously acquired for a subject are analyzed to calculate or approximate intrinsic frequencies in two domains in two domains across the Dicrotic Notch. Together with associated notch timing, heart rate and blood pressure values left ventricle ejection fraction and/or stroke volume can be determination.
摘要翻译： 硬件和软件方法被描述为非侵入性地监测心脏健康。 分析针对受试者各种获得的血流动力学波形，以计算或近似跨越Dicrotic Notch的两个域中的两个域中的固有频率。 与相关的切口定时一起，可以确定心率和血压值左心室射血分数和/或冲程体积。
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公开(公告)号：US09125655B2
公开(公告)日：2015-09-08
申请号：US13185377
申请日：2011-07-18
申请人： Morteza Gharib , Niema Pahlevan
发明人： Morteza Gharib , Niema Pahlevan
CPC分类号： A61M1/122 , A61B5/02 , A61B17/12013 , A61B2017/00022 , A61B2090/064 , A61M1/1005 , A61M1/1056 , A61M1/1058 , A61M1/1067 , A61M1/1086 , A61M1/12 , A61M1/125 , A61M2205/0283 , A61N1/362
摘要： The present invention provides methods and modalities that can modify wave reflection in the vascular system in order to create constructive interactions between existing wave dynamics and new reflective waves for the purpose of lowering the workload on the heart and increasing cardiac output, providing a viable option for the prevention and treatment of many heart conditions and diseases.
摘要翻译： 本发明提供了可以修改血管系统中的波反射以便在现有波动态和新反射波之间产生建设性的相互作用的方法和方式，目的是降低心脏的工作量和增加心输出量，为 预防和治疗许多心脏病和疾病。
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公开(公告)号：US20140046202A1
公开(公告)日：2014-02-13
申请号：US13964631
申请日：2013-08-12
申请人： Niema Pahlevan , Morteza Gharib
发明人： Niema Pahlevan , Morteza Gharib
IPC分类号： A61B5/02 , A61B5/0265 , A61B5/00 , A61B8/06
CPC分类号： A61B5/00 , A61B5/02014 , A61B5/0265 , A61B5/0285 , A61B5/0507 , A61B5/7246 , A61B5/7275 , A61B5/7278 , A61B8/06 , A61B8/0891 , A61B8/485 , A61B8/5223 , G16H50/30
摘要： Hardware and software methodology are described for non-invasive approaches to aortic aneurysm evaluation using ultrasound, microwave, and/or other radiofrequency (RF) techniques. Embodiments can be used to diagnose AAA and other aortic aneurysm conditions by non-invasive measurement and computation of displacement-based wave intensity (DWI) and/or displacement-based reflected wave intensity (DRWI) along the aorta and by comparison of the results to baseline data for a given patent or a population sample catalogue. Deviation of DWI and/or DRWI from a normal condition can be used to assess the severity of the AAA or other aortic aneurysm and any associated rupture risk.
摘要翻译： 描述了使用超声波，微波和/或其他射频（RF）技术的非侵入性主动脉瘤评估方法的硬件和软件方法。 实施例可用于通过非侵入性测量和沿着主动脉计算基于位移的波强度（DWI）和/或基于位移的反射波强度（DRWI）来诊断AAA和其它主动脉瘤病症，并将结果与 给定专利或人口样本目录的基线数据。 DWI和/或DRWI与正常情况的偏差可用于评估AAA或其他主动脉瘤的严重程度和任何相关的破裂风险。
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公开(公告)号：US07955644B2
公开(公告)日：2011-06-07
申请号：US11827169
申请日：2007-07-10
CPC分类号： B29C70/64 , B29K2105/162 , B81C3/008 , B81C2201/034 , B82Y30/00 , B82Y40/00 , C01B32/168 , C01B32/18 , C01B2202/08 , Y10S977/742 , Y10S977/753 , Y10T156/109 , Y10T428/24479
摘要： A method is provided for creating composites by combining pre-fabricated nanoscale structures (nanostructures) and other materials in which the nanostructures are anchored. This method results in anchored nanostructures with their base held and encased within the anchoring material to a specified depth and with a specified length of protrusion of the nanostructures from the anchoring material. This represents a major advance over previous methods of creating composites containing nanostructures which were limited to fully embedded nanostructures or, at best, very limited and uncontrolled protrusion of nanostructures. In summary, the current method involves bringing nanostructures and anchoring materials into physical contact in a controlled fashion and optionally conducting a treatment step to complete the anchoring process.
摘要翻译： 提供了一种通过组合预制纳米尺度结构（纳米结构）和其中纳米结构被锚定的其它材料来产生复合材料的方法。 该方法导致锚定的纳米结构，其基部保持并且被包裹在锚固材料内到达指定的深度并且具有来自锚定材料的纳米结构的特定长度的突出。 这代表了先前创建含有纳米结构的复合材料的方法的重大进步，这些纳米结构限于完全嵌入的纳米结构，或者至多是非常有限的和不受控制的纳米结构突起。 总之，目前的方法涉及使纳米结构和锚定材料以受控的方式物理接触，并且可选地进行处理步骤以完成锚定过程。
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公开(公告)号：US20110125136A1
公开(公告)日：2011-05-26
申请号：US13013733
申请日：2011-01-25
CPC分类号： B01L3/50273 , B01L2200/10 , B01L2300/0864 , B01L2400/0439 , B01L2400/0481 , B01L2400/082 , B01L2400/084 , G01N2035/00148 , G01N2035/1034
摘要： A device and methods for continuous precision blood sampling from a patient with a micro impedance pump as the driver in a microfluidic system. Depending on the needs of medical technologies, the micro impedance pump in the intravascular diagnostic and therapeutic sampling system serves in a forward pumping function for blood sampling, in a backward infusing for therapeutic treatment, and in a valving function for controlling fluid flow.
摘要翻译： 用于在微流体系统中作为驱动器的微阻抗泵的患者进行连续精确采血的装置和方法。 根据医疗技术的需要，血管内诊断和治疗取样系统中的微阻抗泵用于血液采样的正向泵送功能，用于治疗性治疗的反向输注以及用于控制流体流动的阀门功能。
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公开(公告)号：US20100261228A1
公开(公告)日：2010-10-14
申请号：US12756886
申请日：2010-04-08
申请人： Morteza Gharib , Derek Rinderknecht , Randy Keen
发明人： Morteza Gharib , Derek Rinderknecht , Randy Keen
CPC分类号： C07H21/04
摘要： Disclosed herein are methods, devices, and other components for synthesizing polymers. In some embodiments, numerous sites can be multiplexed together to allow for effective nucleic acid synthesis.
摘要翻译： 本文公开了用于合成聚合物的方法，装置和其它组分。 在一些实施方案中，可以将多个位点复合在一起以允许有效的核酸合成。
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公开(公告)号：US20080145616A1
公开(公告)日：2008-06-19
申请号：US11827169
申请日：2007-07-10
CPC分类号： B29C70/64 , B29K2105/162 , B81C3/008 , B81C2201/034 , B82Y30/00 , B82Y40/00 , C01B32/168 , C01B32/18 , C01B2202/08 , Y10S977/742 , Y10S977/753 , Y10T156/109 , Y10T428/24479
摘要： A method is provided for creating composites by combining pre-fabricated nanoscale structures (nanostructures) and other materials in which the nanostructures are anchored. This method results in anchored nanostructures with their base held and encased within the anchoring material to a specified depth and with a specified length of protrusion of the nanostructures from the anchoring material. This represents a major advance over previous methods of creating composites containing nanostructures which were limited to fully embedded nanostructures or, at best, very limited and uncontrolled protrusion of nanostructures. In summary, the current method involves bringing nanostructures and anchoring materials into physical contact in a controlled fashion and optionally conducting a treatment step to complete the anchoring process.
摘要翻译： 提供了一种通过组合预制纳米尺度结构（纳米结构）和其中纳米结构被锚定的其它材料来产生复合材料的方法。 该方法导致锚定的纳米结构，其基部保持并且被包裹在锚固材料内到达指定的深度并且具有来自锚定材料的纳米结构的特定长度的突出。 这代表了先前创建含有纳米结构的复合材料的方法的重大进步，这些纳米结构限于完全嵌入的纳米结构，或者至多是非常有限的和不受控制的纳米结构突起。 总之，目前的方法涉及使纳米结构和锚定材料以受控的方式物理接触，并且可选地进行处理步骤以完成锚定过程。
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公开(公告)号：US07749152B2
公开(公告)日：2010-07-06
申请号：US11329410
申请日：2006-01-09
申请人： Morteza Gharib , Derek Rinderknecht , Idit Avrahami , Brad Sharp
发明人： Morteza Gharib , Derek Rinderknecht , Idit Avrahami , Brad Sharp
IPC分类号： A61N1/362
CPC分类号： A61M1/12 , A61M1/1067
摘要： A pump installed inside a graft in a body such as the human body to force fluid such as blood through that graft. The pump can be one which operates totally from the outside of the graft, forcing fluid through the graft without extending inside the graft. The pump can be an impedance pump, that operates based on the fluidic mismatches between the graft, and other fluid carrying vessels within the human body.
摘要翻译： 安装在诸如人体的体内的移植物内的泵，以通过该移植物迫使诸如血液的流体。 泵可以是完全从移植物外侧操作的泵，迫使流体通过移植物而不在移植物内延伸。 泵可以是阻抗泵，其基于移植物和人体内其他流体携带血管之间的流体错配进行操作。
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公开(公告)号：US20060196642A1
公开(公告)日：2006-09-07
申请号：US11320167
申请日：2005-12-27
IPC分类号： F28D15/00
CPC分类号： H01L23/473 , H01L2924/0002 , H01L2924/3011 , H01L2924/00
摘要： A heat producing device is placed in contact with a heat exchanger that is fluidically coupled to a fluid pump. The fluid pump operates to pumps fluid through a closed fluidic system between the heat exchanger and a spot where the heat can be dissipated. In an aspect, an actuator forces fluid to be pumped without passing through a wall of the pump. One aspect uses an impedance pump as the pumping element.
摘要翻译： 发热装置被放置成与流体耦合到流体泵的热交换器接触。 流体泵操作以将流体泵送在热交换器和可以消散热量的点之间的封闭流体系统中。 在一方面，致动器迫使流体被泵送而不通过泵的壁。 一方面使用阻抗泵作为泵送元件。
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10.发明授权Method for selectively anchoring and exposing large numbers of nanoscale structures 有权选择性锚定和暴露大量纳米尺度结构的方法公开(公告)号：US08846143B2
公开(公告)日：2014-09-30
申请号：US13110877
申请日：2011-05-18
CPC分类号： B32B37/025 , A61M37/0015 , B01D46/546 , B08B17/065 , B29C70/64 , B29K2105/162 , B32B37/06 , B32B37/12 , B32B2037/1253 , B32B2305/72 , B32B2310/0806 , B32B2313/04 , B32B2398/20 , B63B1/32 , B82B3/0014 , B82B3/0047 , B82Y30/00 , B82Y40/00 , C01B32/168 , C01B32/174 , C01B32/18 , C01B2202/08 , F28F13/185 , Y10S977/742 , Y10S977/753 , Y10T428/23979 , Y10T428/24273 , Y10T428/249924
摘要： Methods for fastening nanoscale structures within an anchoring structure to form a nanostructure composite and nanostructure composites formed therefrom. A primary fluid layer is formed on an anchoring substrate. Nanostructures are provided on an initial substrate, the nanostructures having a defined height and orientation with respect to the initial substrate. The nanostructures are introduced to a desired depth in the primary fluid layer, such that the orientation of the nanostructures relative to the growth substrate is substantially maintained. The primary fluid layer comprises one or more fluid layers. Ones of multiple fluid layers are selected such that when altered to form an anchoring structure, a portion of the anchoring structure can be removed, permitting exposure of at least a portion of the nanostructures from the anchoring structure in which they are affixed. The growth substrate is removed. Ends or other parts of nanostructures may be exposed from the anchoring structure.
摘要翻译： 将纳米尺度结构固定在锚固结构内以形成由其形成的纳米结构复合材料和纳米结构复合材料的方法。 主要流体层形成在锚固衬底上。 纳米结构提供在初始基底上，纳米结构相对于初始底物具有限定的高度和取向。 将纳米结构引入初级流体层中所需的深度，使得纳米结构相对于生长衬底的取向基本上保持。 主流体层包括一个或多个流体层。 选择多个流体层的一部分，使得当改变以形成锚定结构时，可以去除锚定结构的一部分，允许至少一部分纳米结构从其所固定的锚定结构暴露。 除去生长底物。 纳米结构的末端或其他部分可能从锚定结构暴露出来。
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