Process for intentional deterioration of the contents of an optical recording medium
    5.
    发明授权
    Process for intentional deterioration of the contents of an optical recording medium 有权
    光学记录介质的内容物的故意恶化的处理

    公开(公告)号:US07924690B2

    公开(公告)日:2011-04-12

    申请号:US12060439

    申请日:2008-04-01

    IPC分类号: G11B7/00

    CPC分类号: G11B7/0055 G11B7/24

    摘要: The invention relates to the field of optical information recording. In order to prevent abusive or fraudulent use of storage media, the invention provides a process for intentional degradation of information by application of a laser power below the normal power for reading information recorded in super-resolution on the media. This process relies on the surprising observation that a laser power below the super-resolution read power produces an irreversible degradation of the information recorded. This observation has been made with regard to media composed of a three-layer structure comprising an InSb or GaSb layer between two ZnS/SiO2 layers. Application for protecting sensitive data.

    摘要翻译: 本发明涉及光信息记录领域。 为了防止对存储介质的滥用或欺诈性的使用,本发明通过将低于正常功率的激光功率应用于介质上以超分辨率记录的信息来提供信息有意降级的过程。 该过程依赖于惊人的观察结果,低于超分辨率读取功率的激光功率产生记录的信息的不可逆的降级。 对于由包含两个ZnS / SiO 2层之间的InSb或GaSb层的三层结构构成的介质进行了这种观察。 保护敏感数据的应用。

    Enhancing surface-generated fluorescence signal emitted by a sample
    6.
    发明授权
    Enhancing surface-generated fluorescence signal emitted by a sample 失效
    增强样品发出的表面产生的荧光信号

    公开(公告)号:US06893876B2

    公开(公告)日:2005-05-17

    申请号:US10129948

    申请日:2000-12-01

    CPC分类号: G01N21/6452

    摘要: A device and process for the amplification of fluorescence emitted by an areal sample. The device includes a support transmitting all or part of a fluorescence signal and configured to support the areal sample and a thin layer interposed between the support and the areal sample. The thin layer has a refractive index greater than the refractive index of the support and than the refractive index of a medium flooding the areal sample during a fluorescence measurement. The thickness of the thin layer is chosen so that the thin layer transmits all or part of the fluorescence signal which is measured after passing through the support.

    摘要翻译: 用于扩增由面状样品发射的荧光的装置和方法。 该装置包括透射全部或部分荧光信号并被配置为支撑面状样品的支撑体和介于载体和面状样品之间的薄层。 薄层的折射率大于支撑体的折射率,而不是在荧光测量期间填充面状样品的介质的折射率。 选择薄层的厚度,使得薄层透过在通过载体之后测量的全部或部分荧光信号。

    Device for enhancing broad band fluorescence with low loss and biological or chemical optic sensor using the same
    8.
    发明授权
    Device for enhancing broad band fluorescence with low loss and biological or chemical optic sensor using the same 有权
    用于增加具有低损耗的宽带荧光和使用其的生物或化学光学传感器的装置

    公开(公告)号:US07718422B2

    公开(公告)日:2010-05-18

    申请号:US10450100

    申请日:2001-12-12

    IPC分类号: G01N33/551

    摘要: The invention concerns a device for enhancing fluorescence comprising a support (10) carrying fluorescence enhancement means (11), the fluorescence enhancement means offering a reception surface for chemical or biological elements intended to be read by detection of a fluorescence signal emitted by a fluorophore, associated with the chemical or biological elements, under the effect of an excitation light beam. The fluorescence enhancement means (11) is made up of a thin, transparent, dielectric layer or a stack of thin, transparent, dielectric layers (12 to 16) ensuring a mirror function for the fluorescence signal and excitation light beam, the material of the thin layer or of each thin layer of the stack being chosen from among the following materials: TiO2, Ta2O5, HfO2, ZrO2, MgO, SiO2, Si3N4, MgF2 and YF3. The fluorescence enhancement device may be used for a biological or chemical optic sensor.

    摘要翻译: 本发明涉及一种用于增强荧光的装置,其包括载有荧光增强装置(11)的载体(10),所述荧光增强装置提供用于通过检测由荧光团发射的荧光信号而被读取的化学或生物元件的接收表面, 在激发光束的作用下与化学或生物元素相关联。 荧光增强装置(11)由薄的,透明的介电层或薄的,透明的电介质层(12至16)组成,确保了荧光信号和激发光束的反射镜功能, 薄层或每层薄层选自以下材料:TiO 2,Ta 2 O 5,HfO 2,ZrO 2,MgO,SiO 2,Si 3 N 4,MgF 2和YF 3。 荧光增强装置可用于生物或化学光学传感器。

    Biochip support comprising thin layers of sol-gel material and production method thereof
    10.
    发明申请
    Biochip support comprising thin layers of sol-gel material and production method thereof 审中-公开
    生物芯片载体包括薄层的溶胶 - 凝胶材料及其制备方法

    公开(公告)号:US20060223167A1

    公开(公告)日:2006-10-05

    申请号:US10555580

    申请日:2004-05-06

    IPC分类号: C12M1/34 H01L21/00

    摘要: The invention relates to a biochip support comprising a substrate supporting at least one porous layer of material on a first face, the said layer being designed to fix biological molecules onto the said layer and in the volume of this layer, the said support being characterized in that the said layer is a thin optical layer of material prepared by the sol-gel method and for which the refraction index is less than the refraction index of the substrate. The invention also relates to a process grafting of biological molecules onto and into the thin layer of material prepared by the sol-gel method on the first face of the biochip support. This process comprises the following steps: a sol is prepared that will provide the sol-gel material, biomolecules are incorporated into the material during its preparation, biomolecules are grafted into the material during its preparation, a thin layer of the said sol is deposited on the first face of the substrate, the thin layer of sol-gel material is obtained starting from the thin layer of sol. Finally, one particular embodiment of the grafting process also comprises a structuring step of the thin layer of sol-gel material to obtain a network of pads or wells over all or part of the biochip support.

    摘要翻译: 本发明涉及一种生物芯片载体,其包括在第一面上支撑至少一种多孔材料层的基底,所述层被设计成将生物分子固定在所述层上并且在该层的体积中,所述载体的特征在于 所述层是通过溶胶 - 凝胶法制备并且折射率小于衬底的折射率的薄的材料光学层。 本发明还涉及生物分子在生物芯片载体的第一面上通过溶胶 - 凝胶法制备的薄层材料的接枝过程。 该方法包括以下步骤:制备将提供溶胶 - 凝胶材料的溶胶,在制备过程中将生物分子并入材料中,生物分子在其制备过程中被接枝到材料中,所述溶胶的薄层沉积在 基材的第一面,从溶胶的薄层开始获得溶胶 - 凝胶材料的薄层。 最后,接枝方法的一个具体实施方案还包括溶胶 - 凝胶材料薄层的结构化步骤,以在全部或部分生物芯片载体上获得垫或孔的网络。