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1.发明申请MICROFLUIDIC ANALYTICAL DEVICE FOR ANALYSIS OF CHEMICAL OR BIOLOGICAL SAMPLES, METHOD AND SYSTEM THEREOF 审中-公开用于化学或生物样品分析的微流化分析装置，其方法和系统公开(公告)号：US20090311796A1
公开(公告)日：2009-12-17
申请号：US12482707
申请日：2009-06-11
申请人： Patrick Griss , Rainer Jaeggi , Goran Savatic , Vuk Siljegovic
发明人： Patrick Griss , Rainer Jaeggi , Goran Savatic , Vuk Siljegovic
CPC分类号： B01L3/50273 , B01L2200/10 , B01L2300/0654 , B01L2300/0803 , B01L2300/0887 , B01L2300/168 , B01L2400/0409 , B01L2400/0688 , C12Q1/54 , G01N21/07 , G01N33/491 , Y10T436/144444 , Y10T436/146666 , Y10T436/15 , Y10T436/166666 , Y10T436/171538 , Y10T436/175383 , Y10T436/201666 , Y10T436/204165
摘要： An analytical device for analysis of chemical or biological samples, a method of using such a device, based on rotation of the device, integrated sample dosing and optical detection, and a system comprising such a device are disclosed. The analytical device comprises a device body having a liquid processing unit. The liquid processing unit comprises a mixing chamber for mixing a sample with a reagent, a sample dosing chamber for delivering a defined volume of the sample to the mixing chamber, and a reagent channel for delivering the reagent to be mixed with the sample, wherein the mixing chamber also serves as a detection chamber.
摘要翻译： 公开了用于分析化学或生物样品的分析装置，基于装置的旋转，集成的样品计量和光学检测使用这种装置的方法，以及包括这种装置的系统。 分析装置包括具有液体处理单元的装置主体。 液体处理单元包括用于将样品与试剂混合的混合室，用于将限定体积的样品输送到混合室的样品计量室，以及用于输送要与样品混合的试剂的试剂通道，其中 混合室也用作检测室。
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公开(公告)号：US07586612B2
公开(公告)日：2009-09-08
申请号：US11463110
申请日：2006-08-08
IPC分类号： G01N21/00
CPC分类号： G01N21/0303 , B01L3/502715 , B01L2300/0654 , B01L2300/0806 , B01L2300/168 , G01N35/00069
摘要： On an analytical device for photometric analysis of chemistry and/or fluid samples comprising a rotatable disk-like body, a plurality of receptacles for fluid samples and optics for guiding light beams through the receptacles are arranged. At least part of the optics are designed and/or arranged such that at least part of the light beams is deflected and guided through the receptacles at an angle to the radially outward direction on the disk-like body which means at an angle to the radius, connecting the respective optics with the rotation axis of the disk-like body.
摘要翻译： 在用于对包括可旋转的盘状体的化学和/或流体样品进行光度分析的分析装置上，布置了多个用于流体样品的容器和用于将光束引导通过容器的光学器件。 光学元件的至少一部分被设计和/或布置成使得至少部分光束被偏转并且引导通过插座与盘状主体上的径向向外方向成一定角度，这意味着与半径成一定角度 将各光学元件与盘状体的旋转轴连接。
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公开(公告)号：US20070165229A1
公开(公告)日：2007-07-19
申请号：US11463110
申请日：2006-08-08
IPC分类号： G01N21/00
CPC分类号： G01N21/0303 , B01L3/502715 , B01L2300/0654 , B01L2300/0806 , B01L2300/168 , G01N35/00069
摘要： On a analytical device for photometric analysis of chemistry and/or fluid samples comprising a rotatable disk-like body (1) a plurality of receptacles (7) for fluid samples and optical means (9) for guiding light beams through the receptacles are arranged. At least part of the optical means (9) are designed and/or arranged such that at least part of the light beams is deflected and guided through the receptacles at an angle to the radially outward direction on the disk-like body (1) which means at an angle to the radius, connecting the respective optical means with the rotation axis (3) of the disk-like body (1).
摘要翻译： 在用于对包括可旋转盘状体（1）的化学和/或流体样品进行光度分析的分析装置上，布置有用于流体样品的多个容器（7）和用于将光束引导通过容器的光学装置（9）。 光学装置（9）的至少一部分被设计和/或布置成使得至少部分光束被偏转和引导通过插座与盘状主体（1）上的径向向外方向成一角度， 意指与半径成一定角度，将相应的光学装置与盘状体（1）的旋转轴线（3）相连接。
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公开(公告)号：US07682819B2
公开(公告)日：2010-03-23
申请号：US11777164
申请日：2007-07-12
申请人： Emad Sarofim , Goran Savatic
发明人： Emad Sarofim , Goran Savatic
CPC分类号： B01L7/52 , B01L7/00 , B01L2300/1827 , B01L2300/1883 , Y02P20/582
摘要： An instrument and method is provided that conveniently allows rapid amplification of nucleic acids.
摘要翻译： 提供了方便地允许核酸快速扩增的仪器和方法。
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公开(公告)号：US07666664B2
公开(公告)日：2010-02-23
申请号：US11777203
申请日：2007-07-12
申请人： Emad Sarofim , Goran Savatic
发明人： Emad Sarofim , Goran Savatic
CPC分类号： B01L9/527 , B01J2219/00873 , B01L3/5027 , B01L7/52 , B01L2300/0816 , B01L2300/1827 , B01L2300/1838 , B01L2300/185 , Y02P20/582
摘要： An instrument and method is provided that conveniently allows rapid amplification of nucleic acids. The instrument comprises in the following order at least one substantially flat temperature sensor element; a heat conducting substrate and a heater layer, whereby the heat conducting substrate comprises one or more channels permeable for fluid.
摘要翻译： 提供了方便地允许核酸快速扩增的仪器和方法。 仪器按以下顺序包括至少一个基本平坦的温度传感器元件; 导热衬底和加热器层，由此导热衬底包括可渗透流体的一个或多个通道。
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公开(公告)号：US20080026430A1
公开(公告)日：2008-01-31
申请号：US11777164
申请日：2007-07-12
申请人： Emad Sarofim , Goran Savatic
发明人： Emad Sarofim , Goran Savatic
CPC分类号： B01L7/52 , B01L7/00 , B01L2300/1827 , B01L2300/1883 , Y02P20/582
摘要： An instrument and method is provided that conveniently allows rapid amplification of nucleic acids.
摘要翻译： 提供了方便地允许核酸快速扩增的仪器和方法。
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公开(公告)号：US20050208464A1
公开(公告)日：2005-09-22
申请号：US10502556
申请日：2003-01-22
申请人： Amar Rida , Olivier Elsenhans , Martin Gijs , Goran Savatic
发明人： Amar Rida , Olivier Elsenhans , Martin Gijs , Goran Savatic
摘要： An apparatus for retaining magnetic particles within a segment of a flow-through cell during flow of a fluid through the cell comprises (a) optionally, an electrical current source; (b) an electromagnet having a winding connected to the current source and an air gap between at least one pair of poles each of which has a corrugated outer surface and (c) a flow-through cell which is configured and dimensioned to receive an amount of magnetic particles to be retained within the flow-through cell and to allow flow of a liquid through the flow-through cell. The liquid carries molecules or particles to be captured by means of the magnetic particles. A portion of the flow-through cell is inserted in air gap.
摘要翻译： 一种用于在流体通过电池的流动期间将磁性颗粒保持在流通池的段内的装置包括（a）可选地，电流源; （b）具有连接到电流源的绕组的电磁体和在至少一对磁极之间的空气间隙，每个磁极具有波纹状的外表面，以及（c）流通电池，其配置和尺寸设置为接收一定量 的磁性颗粒保留在流通池内并允许液体流过流通池。 液体携带通过磁性颗粒捕获的分子或颗粒。 流通池的一部分插入气隙中。
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公开(公告)号：US20060235335A1
公开(公告)日：2006-10-19
申请号：US11389919
申请日：2006-03-27
申请人： Olivier Elsenhans , Emad Sarofim , Goran Savatic
发明人： Olivier Elsenhans , Emad Sarofim , Goran Savatic
IPC分类号： A61B5/00
CPC分类号： B29C45/1676 , B01L3/502707 , B01L3/502715 , B01L3/50825 , B01L7/52 , B01L2200/027 , B01L2200/12 , B01L2300/042 , B01L2300/044 , B01L2300/0816 , B01L2300/0887 , B29C65/02 , B29C65/08 , B29C65/16 , B29C65/1606 , B29C65/1616 , B29C65/1619 , B29C65/48 , B29C65/58 , B29C66/53461 , B29K2021/003 , B29K2023/06 , B29K2023/12 , B29K2025/00 , B29K2033/12 , B29K2069/00 , B29K2101/12 , G01N35/1079 , B29C66/71
摘要： Manufacture of a device having a body comprising a cavity with a fluid port made from an elastomeric material adhering to the body is disclosed. The device can be used advantageously in reliable analyses in automated procedures.
摘要翻译： 公开了一种具有主体的装置，该主体包括具有由附着于主体的弹性体材料制成的流体端口的空腔。 该装置可以有利地用于自动化程序中的可靠分析。
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公开(公告)号：US07601265B2
公开(公告)日：2009-10-13
申请号：US10502556
申请日：2003-01-22
申请人： Amar Rida , Olivier Elsenhans , Martin Gijs , Goran Savatic
发明人： Amar Rida , Olivier Elsenhans , Martin Gijs , Goran Savatic
IPC分类号： C02F1/48
摘要： An apparatus for retaining magnetic particles within a segment of a flow-through cell during flow of a fluid through the cell comprises (a) optionally, an electrical current source; (b) an electromagnet having a winding connected to the current source and an air gap between at least one pair of poles each of which has a corrugated outer surface and (c) a flow-through cell which is configured and dimensioned to receive an amount of magnetic particles to be retained within the flow-through cell and to allow flow of a liquid through the flow-through cell. The liquid carries molecules or particles to be captured by means of the magnetic particles. A portion of the flow-through cell is inserted in air gap.
摘要翻译： 一种用于在流体通过电池的流动期间将磁性颗粒保持在流通池的段内的装置包括（a）可选地，电流源; （b）具有连接到电流源的绕组的电磁体和在至少一对磁极之间的空气间隙，每个磁极具有波纹状的外表面，以及（c）流通电池，其配置和尺寸设置为接收一定量 的磁性颗粒保留在流通池内并允许液体流过流通池。 液体携带通过磁性颗粒捕获的分子或颗粒。 流通池的一部分插入气隙中。
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公开(公告)号：US20090227006A1
公开(公告)日：2009-09-10
申请号：US12373276
申请日：2007-07-05
申请人： Martin Kopp , Hans-Peter Wahl , Emad Sarofim , Oliver Elsenhans , Goran Savatic , Roland Christof Hutter
发明人： Martin Kopp , Hans-Peter Wahl , Emad Sarofim , Oliver Elsenhans , Goran Savatic , Roland Christof Hutter
IPC分类号： C12M1/00
CPC分类号： B01L3/502715 , G01N35/0099 , G01N2035/00346
摘要： The embodiments of the present invention are directed to an automatic apparatus (55), which is designed for performing nucleic acid analysis, optionally including sample preparation, with integrated disposable sample holding and processing devices (1), which devices (1) comprise a sample to be analyzed with the apparatus (55). The apparatus (55) comprises workstations (17, 40) for receiving, holding and processing such integrated disposable devices (1), a reagents station (56) for reagents (25), transfer means (36) for performing movements of an actuator, fluid actuation means for processing the sample (32) and reagents in said disposable devices (1), temperature control means (37) for heating or cooling, detection means for measuring a property of the processed samples (32), and control means for controlling the sample (32) preparation, the handling of the disposable devices (1) and the sample analysis performed by the apparatus (55).
摘要翻译： 本发明的实施例涉及一种自动装置（55），其被设计用于执行核酸分析，任选地包括样品制备，具有集成的一次性样品保持和处理装置（1），所述装置（1）包括样品 用装置（55）进行分析。 装置（55）包括用于接收，保持和处理这种集成的一次性装置（1），用于试剂（25）的试剂台（56），用于执行致动器的运动的传送装置（36） 用于处理所述一次性装置（1）中的样品（32）和试剂的流体致动装置，用于加热或冷却的温度控制装置（37），用于测量经处理样品（32）的性质的检测装置，以及用于控制 样品（32）制备，一次性装置（1）的处理和由装置（55）进行的样品分析。
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