Apparatus and method for ion capture and production
    2.
    发明申请
    Apparatus and method for ion capture and production 审中-公开
    用于离子捕获和制备的装置和方法

    公开(公告)号:US20070001114A1

    公开(公告)日:2007-01-04

    申请号:US11172217

    申请日:2005-06-29

    IPC分类号: H01J49/10

    CPC分类号: H01J49/0418

    摘要: The present invention relates to an apparatus and method for producing ions. The apparatus may be used separately as an ion source or in combination with a mass spectrometry system. The ion source of the present invention provides an ionization device for producing ions, a substrate for capturing, storing and releasing ions produced by the ionization device, a conductive material in contact with the substrate for receiving an electrical pulse, and a voltage source electrically connected to the conductive material for applying an electrical pulse to the conductive material and substrate to release the ions captured by the substrate. Also disclosed is a method for storing and releasing ions using the disclosed apparatus.

    摘要翻译: 本发明涉及一种用于生产离子的装置和方法。 该装置可以单独用作离子源或与质谱系统组合使用。 本发明的离子源提供用于产生离子的离子化装置,用于捕获,存储和释放由离子化装置产生的离子的基板,与基板接触的用于接收电脉冲的导电材料和电连接的电压源 涉及用于将电脉冲施加到导电材料和衬底以释放由衬底捕获的离子的导电材料。 还公开了使用所公开的装置来存储和释放离子的方法。

    Micro matrix ion generator for analyzers
    3.
    发明申请
    Micro matrix ion generator for analyzers 失效
    用于分析仪的微型离子发生器

    公开(公告)号:US20050139765A1

    公开(公告)日:2005-06-30

    申请号:US11064545

    申请日:2005-02-23

    IPC分类号: H01J49/04 B01D59/44 H01J49/00

    摘要: A source of ions for an analyzer includes a reservoir for containing a liquid, a manifold having a plurality of nozzles, a conduit connecting the reservoir to the manifold and a counter electrode having a potential different between the counter electrode and the nozzles to enable liquid to be ejected from the nozzles in droplets and to enable ions to be ejected from the droplets.

    摘要翻译: 用于分析器的离子源包括用于容纳液体的储存器,具有多个喷嘴的歧管,将储存器连接到歧管的导管和在对电极和喷嘴之间具有不同电位的对电极, 从喷嘴喷出液滴,并使离子从液滴中喷出。

    Method and apparatus for surface desorption ionization by charged particles
    4.
    发明申请
    Method and apparatus for surface desorption ionization by charged particles 有权
    带电粒子表面解吸电离的方法和装置

    公开(公告)号:US20070228271A1

    公开(公告)日:2007-10-04

    申请号:US11398305

    申请日:2006-04-04

    IPC分类号: H01J49/14

    CPC分类号: H01J49/142

    摘要: An apparatus and method for generating analyte ions from a sample. An ion generating device is provided having a chamber with an outlet and a surface having a material and means for applying a high velocity gas flow through the chamber toward the outlet such that charged particles are produced by physical interaction between the high velocity gas and the material. The charged particles then induce the generation of primary ions by interaction with molecules of the high velocity gas. The primary ions are emitted from the outlet of the ion generating device toward a sample-bearing surface and analyte ions are generated by impact of the primary ions on the analyte sample on the surface.

    摘要翻译: 一种用于从样品中产生分析物离子的装置和方法。 提供一种离子产生装置,其具有具有出口的腔室和具有材料的表面,以及用于将高速气流经由腔室朝向出口施加的装置,使得通过高速气体和材料之间的物理相互作用产生带电粒子 。 带电粒子然后通过与高速气体分子的相互作用诱导产生初级离子。 主要离子从离子产生装置的出口朝向样品承载表面发射,分析物离子通过主离子冲击表面上的分析物样品而产生。

    Curved conduit ion sampling device and method
    5.
    发明申请
    Curved conduit ion sampling device and method 失效
    曲线管离子采样装置及方法

    公开(公告)号:US20070235642A1

    公开(公告)日:2007-10-11

    申请号:US11398163

    申请日:2006-04-05

    IPC分类号: H01J49/00

    CPC分类号: H01J49/062

    摘要: An ion sampling apparatus for use in a mass spectrometry system. The ion sampling apparatus includes a target support for receiving a sample, an irradiation source for emitting energetic radiation or particles toward the target support, and a conduit having a curved end and a longitudinal axis, the curved end having an inlet with a central axis, the conduit being adjacent to the target support. The longitudinal axis of the conduit and the central axis of the inlet intersect to define an angle that is between about 20 degrees and about 210 degrees.

    摘要翻译: 用于质谱系统的离子取样装置。 离子采样设备包括用于接收样品的目标支撑体,用于向目标支撑体发射能量辐射或颗粒的辐射源,以及具有弯曲端部和纵向轴线的导管,该弯曲端部具有带有中心轴线的入口, 导管与目标支撑件相邻。 导管的纵向轴线和入口的中心轴线相交以限定约20度至约210度之间的角度。

    Nanospray ionization device and method
    8.
    发明申请
    Nanospray ionization device and method 有权
    纳米喷雾电离装置及方法

    公开(公告)号:US20070023676A1

    公开(公告)日:2007-02-01

    申请号:US11171976

    申请日:2005-06-29

    IPC分类号: H01J27/00

    CPC分类号: H01J49/165 H01J49/0468

    摘要: The present invention provides an apparatus and method for use with a mass spectrometry system. The invention provides an ion source for providing radiative heating to an ionization region. The ion source includes a nanospray ionization device for producing ions and a conduit adjacent to the ionization device for receiving ions from the ionization device. The conduit includes a conductive material for providing indirect radiative heating to the ionization region. Direct radiative heating may also be provided using a heater in the conduit. The ion source may be used separately or in conjunction with the mass spectrometry system. When used in conjunction with a mass spectrometry system a detector may also be employed down stream from the device. A method for desolvating an analyte using the device is also disclosed.

    摘要翻译: 本发明提供了一种与质谱系统一起使用的装置和方法。 本发明提供了一种用于向电离区域提供辐射加热的离子源。 离子源包括用于产生离子的纳米喷雾离子化装置和与电离装置相邻的导管,用于从离子化装置接收离子。 导管包括用于向电离区提供间接辐射加热的导电材料。 也可以使用导管中的加热器来提供直接辐射加热。 离子源可以单独使用或与质谱系统结合使用。 当与质谱系统结合使用时,也可以从装置下游使用检测器。 还公开了使用该装置对分析物进行脱溶剂的方法。

    Nanospray ion source with multiple spray emitters
    9.
    发明申请
    Nanospray ion source with multiple spray emitters 审中-公开
    具有多个喷射发射体的纳米喷雾离子源

    公开(公告)号:US20060208186A1

    公开(公告)日:2006-09-21

    申请号:US11081325

    申请日:2005-03-15

    IPC分类号: H01J49/10

    CPC分类号: H01J49/10

    摘要: The present invention provides an apparatus and method for use with a mass spectrometer. The invention provides a mass spectrometer system for non-pneumatic ion production, including a non-pneumatic nanospray ionization source. The nanospray ionization source has a first non-pneumatic ion spray emitter for producing ions; a conduit adjacent to the ion spray emitter, the conduit having an aperture designed for receiving ions from the ion spray emitter; a first electrode for directing the ions from the ion spray emitter toward the aperture of the capillary; and a conduit electrode for directing ions into the conduit; and detector down stream from the capillary for detecting ions produced by the non-pneumatic nanospray ionization source. The invention also provides a non-pneumatic nanospray ionization source, comprising a first non-pneumatic ion spray emitter for producing ions; a conduit adjacent to the ion spray emitter, the conduit having an aperture designed for receiving ions from the ion spray emitter; a first electrode for directing ions from the ion spray emitter toward the aperture of the conduit and a conduit electrode for directing ions into the conduit. Also disclosed is a method for producing ions using a nanospray ionization source.

    摘要翻译: 本发明提供了一种与质谱仪一起使用的装置和方法。 本发明提供了一种用于非气动离子生产的质谱仪系统,包括非气动纳米喷雾电离源。 纳米喷雾电离源具有用于产生离子的第一非气动离子喷射发射体; 邻近离子喷射发射器的导管,导管具有设计用于接收离子喷射发射器的离子的孔; 用于将离子从离子喷射器引导到毛细管的孔的第一电极; 以及用于将离子引导到导管中的导管电极; 并从毛细管下游探测由非气动纳米喷雾电离源产生的离子。 本发明还提供一种非气动纳米喷雾电离源,包括用于产生离子的第一非气动离子喷射发射体; 邻近离子喷射发射器的导管,导管具有设计用于接收离子喷射发射器的离子的孔; 用于将离子从离子喷射器引导到导管的孔的第一电极和用于将离子引导到导管中的导管电极。 还公开了使用纳米喷雾电离源产生离子的方法。