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公开(公告)号：US20080283184A1
公开(公告)日：2008-11-20
申请号：US10599247
申请日：2005-03-28
CPC分类号： B65D81/267 , B31B50/8122 , B65B61/20 , B65D75/326 , B65D81/2076 , B65D81/2084 , Y10T156/1052 , Y10T156/1062
摘要： The present invention relates to a method of attaching an active film (5) onto a flexible package comprising the steps of heating a foil (2); applying an active film (5) to the foil (2); and applying sufficient pressure to the active film (5) and foil (2) combination and sufficient heat to the foil (2) so that active film (5) adheres to the foil (2). In one example, the active film (5) comprises two components and wherein the two components are an active agent and a polymer. In another example, the active agent is an absorbing material.
摘要翻译： 本发明涉及一种将活性膜（5）附着在柔性包装上的方法，包括加热箔（2）的步骤; 将活性膜（5）施加到所述箔（2）上; 并向活性膜（5）和箔（2）施加足够的压力并将合金和足够的热量施加到箔（2），使得活性膜（5）粘附到箔（2）上。 在一个实例中，活性膜（5）包含两种组分，其中两种组分是活性剂和聚合物。 在另一个实例中，活性剂是吸收材料。
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公开(公告)号：US08142603B2
公开(公告)日：2012-03-27
申请号：US10599247
申请日：2005-03-28
CPC分类号： B65D81/267 , B31B50/8122 , B65B61/20 , B65D75/326 , B65D81/2076 , B65D81/2084 , Y10T156/1052 , Y10T156/1062
摘要： The present invention relates to a method of attaching an active film (5) onto a flexible package comprising the steps of heating a foil (2); applying an active film (5) to the foil (2); and applying sufficient pressure to the active film (5) and foil (2) combination and sufficient heat to the foil (2) so that active film (5) adheres to the foil (2). In one example, the active film (5) comprises two components and wherein the two components are an active agent and a polymer. In another example, the active agent is an absorbing material.
摘要翻译： 本发明涉及一种将活性膜（5）附着在柔性包装上的方法，包括加热箔（2）的步骤; 将活性膜（5）施加到所述箔（2）上; 并向活性膜（5）和箔（2）施加足够的压力并将合金和足够的热量施加到箔（2），使得活性膜（5）粘附到箔（2）上。 在一个实例中，活性膜（5）包含两种组分，其中两种组分是活性剂和聚合物。 在另一个实例中，活性剂是吸收材料。
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公开(公告)号：US20100298738A1
公开(公告)日：2010-11-25
申请号：US12779007
申请日：2010-05-12
申请人： John T. Felts , Thomas E. Fisk , Robert S. Abrams , John Ferguson , Jonathan R. Freedman , Robert J. Pangborn , Peter J. Sagona
发明人： John T. Felts , Thomas E. Fisk , Robert S. Abrams , John Ferguson , Jonathan R. Freedman , Robert J. Pangborn , Peter J. Sagona
IPC分类号： A61M5/315 , A61B5/153 , A61J1/14 , B65G37/00 , C23C16/50 , C23C16/00 , C23C16/40 , B05D3/00 , B05C13/00 , B05C11/00 , C12M1/00 , G01N7/00 , F16C33/00
CPC分类号： C23C16/50 , A61M5/31513 , B05D1/62 , B05D5/08 , B05D7/02 , B65D25/14 , C23C16/045 , C23C16/401 , C23C16/505 , C23C16/52 , C23C16/54 , G01N15/082 , G01N2033/0096 , Y10T428/24975 , Y10T428/31663
摘要： Methods for processing a vessel, for example to provide a gas barrier or lubricity, are disclosed. First and second PECVD or other vessel processing stations or devices and a vessel holder comprising a vessel port are provided. An opening of the vessel can be seated on the vessel port. The interior surface of the seated vessel can be processed via the vessel port by the first and second processing stations or devices. Vessel barrier, lubricity and hydrophobic coatings and coated vessels, for example syringes and medical sample collection tubes are disclosed. A vessel processing system and vessel inspection apparatus and methods are also disclosed.
摘要翻译： 公开了处理容器的方法，例如提供阻气或润滑性。 提供第一和第二PECVD或其他容器加工站或装置以及包括容器端口的容器保持器。 船只的开口可以坐在船只港口上。 坐便器的内表面可以通过第一和第二处理站或设备经容器端口处理。 公开了船舶屏障，润滑性和疏水涂层以及涂覆的容器，例如注射器和医用样品收集管。 还公开了一种容器处理系统和容器检查装置和方法。
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公开(公告)号：US09878101B2
公开(公告)日：2018-01-30
申请号：US13240797
申请日：2011-09-22
申请人： John T. Felts , Thomas E. Fisk , Robert S. Abrams , John Ferguson , Jonathan R. Freedman , Robert J. Pangborn , Peter J. Sagona
发明人： John T. Felts , Thomas E. Fisk , Robert S. Abrams , John Ferguson , Jonathan R. Freedman , Robert J. Pangborn , Peter J. Sagona
CPC分类号： A61M5/3129 , A61M5/31513 , A61M2005/3131
摘要： A package including a vessel made of cyclic olefin polymer (COP) resin, a CVD coating on a vessel, and a medicament comprising at least one protein, peptide, and/or DNA sequence is disclosed. Methods for processing a vessel, for example to provide lubricity or hydrophobicity, are also disclosed. The interior surface of the seated vessel can be processed via the vessel port by PECVD. Vessel barrier, lubricity and hydrophobic coatings and coated vessels, for example syringes and medical sample collection tubes are disclosed.
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公开(公告)号：US08512796B2
公开(公告)日：2013-08-20
申请号：US13169811
申请日：2011-06-27
申请人： John T. Felts , Thomas E. Fisk , Robert S. Abrams , John Ferguson , Jonathan R. Freedman , Robert J. Pangborn , Peter J. Sagona
发明人： John T. Felts , Thomas E. Fisk , Robert S. Abrams , John Ferguson , Jonathan R. Freedman , Robert J. Pangborn , Peter J. Sagona
CPC分类号： A61B5/150206 , A61B5/154 , A61L31/088 , A61L31/10 , A61L31/14 , A61L2400/10 , A61L2420/02 , A61L2420/08 , B05C13/00 , B05C13/025 , B23Q7/04 , B23Q7/1494 , C23C16/045 , C23C16/401 , C23C16/458 , C23C16/50 , C23C16/505 , C23C16/52 , C23C16/54 , G01N15/082 , G01N23/2273 , G01N30/7206 , G01N33/00 , G01N2033/0096 , Y10T428/13 , Y10T428/1383
摘要： Methods for processing a vessel, for example to provide a gas barrier or lubricity, are disclosed. First and second PECVD or other vessel processing stations or devices and a vessel holder comprising a vessel port are provided. An opening of the vessel can be seated on the vessel port. The interior surface of the seated vessel can be processed via the vessel port by the first and second processing stations or devices. Vessel barrier, lubricity and hydrophobic coatings and coated vessels, for example syringes and medical sample collection tubes are disclosed. A vessel processing system and vessel inspection apparatus and methods are also disclosed, for example using material outgassed from a surface to inspect the properties of a surface coating.
摘要翻译： 公开了处理容器的方法，例如提供阻气或润滑性。 提供第一和第二PECVD或其他容器加工站或装置以及包括容器端口的容器保持器。 船只的开口可以坐在船只港口上。 坐便器的内表面可以通过第一和第二处理站或设备经容器端口处理。 公开了船舶屏障，润滑性和疏水涂层以及涂覆的容器，例如注射器和医用样品收集管。 还公开了容器处理系统和容器检查装置和方法，例如使用从表面去除的材料来检查表面涂层的性质。
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6.发明申请PASSIVATION, pH PROTECTIVE OR LUBRICITY COATING FOR PHARMACEUTICAL PACKAGE, COATING PROCESS AND APPARATUS 审中-公开钝化，pH值保护或润滑涂料用于药物包装，涂装工艺和装置公开(公告)号：US20150021339A1
公开(公告)日：2015-01-22
申请号：US14357418
申请日：2012-11-09
申请人： John T. Felts , Thomas E. Fisk , Robert S. Abrams , John Ferguson , Jonathan R. Freedman , Robert J. Pangborn , Peter J. Sagona , Christopher Weikart
发明人： John T. Felts , Thomas E. Fisk , Robert S. Abrams , John Ferguson , Jonathan R. Freedman , Robert J. Pangborn , Peter J. Sagona , Christopher Weikart
IPC分类号： B65D25/14
CPC分类号： B65D25/14 , A61J1/05 , A61M5/3129 , A61M2005/3109 , A61M2005/3131 , C23C16/045 , C23C16/30 , C23C16/36 , C23C16/401 , C23C16/507
摘要： A method for providing a passivation layer or pH protective coating on a substrate surface by PECVD is provided, the method comprising generating a plasma from a gaseous reactant comprising polymerizing gases. The lubricity, passivation, pH protective, hydrophobicity, and/or barrier properties of the passivation layer or pH protective coating are set by setting the ratio of the O2 to the organosilicon precursor in the precursor feed, and/or by setting the electric power used for generating the plasma. In particular, a passivation layer or pH protective coating made by the method is provided. Pharmaceutical packages coated by the method and the use of such packages protecting a composition contained in the vessel against mechanical and/or chemical effects of the surface of the package without a passivation layer or pH protective coating material are also provided.
摘要翻译： 提供了一种通过PECVD在衬底表面上提供钝化层或pH保护涂层的方法，该方法包括从包含聚合气体的气态反应物产生等离子体。 钝化层或pH保护涂层的润滑性，钝化性，pH保护性，疏水性和/或阻隔性能通过设定前体进料中O 2与有机硅前体的比例和/或通过设定所用的功率来设定 用于产生等离子体。 特别地，提供了由该方法制成的钝化层或pH保护涂层。 还提供了通过该方法涂覆的药物包装，并且使用这种包装保护容器中包含的组合物免受包装表面的机械和/或化学作用而没有钝化层或pH保护涂层材料。
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公开(公告)号：US20120123345A1
公开(公告)日：2012-05-17
申请号：US13240797
申请日：2011-09-22
申请人： John T. Felts , Thomas E. Fisk , Robert S. Abrams , John Ferguson , Jonathan R. Freedman , Robert J. Pangborn , Peter J. Sagona
发明人： John T. Felts , Thomas E. Fisk , Robert S. Abrams , John Ferguson , Jonathan R. Freedman , Robert J. Pangborn , Peter J. Sagona
CPC分类号： A61M5/3129 , A61M5/31513 , A61M2005/3131
摘要： A package including a vessel made of cyclic olefin polymer (COP) resin, a CVD coating on a vessel, and a medicament comprising at least one protein, peptide, and/or DNA sequence is disclosed. Methods for processing a vessel, for example to provide lubricity or hydrophobicity, are also disclosed. The interior surface of the seated vessel can be processed via the vessel port by PECVD. Vessel barrier, lubricity and hydrophobic coatings and coated vessels, for example syringes and medical sample collection tubes are disclosed.
摘要翻译： 公开了一种包括由环烯烃聚合物（COP）树脂制成的容器，容器上的CVD涂层和包含至少一种蛋白质，肽和/或DNA序列的药物的包装。 还公开了处理容器的方法，例如提供润滑性或疏水性。 坐便器的内表面可以通过PECVD通过容器端口进行处理。 公开了船舶屏障，润滑性和疏水涂层以及涂覆的容器，例如注射器和医用样品收集管。
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公开(公告)号：US20110252899A1
公开(公告)日：2011-10-20
申请号：US13169811
申请日：2011-06-27
申请人： John T. Felts , Thomas E. Fisk , Robert S. Abrams , John Ferguson , Jonathan R. Freedman , Robert J. Pangborn , Peter J. Sagona
发明人： John T. Felts , Thomas E. Fisk , Robert S. Abrams , John Ferguson , Jonathan R. Freedman , Robert J. Pangborn , Peter J. Sagona
CPC分类号： A61B5/150206 , A61B5/154 , A61L31/088 , A61L31/10 , A61L31/14 , A61L2400/10 , A61L2420/02 , A61L2420/08 , B05C13/00 , B05C13/025 , B23Q7/04 , B23Q7/1494 , C23C16/045 , C23C16/401 , C23C16/458 , C23C16/50 , C23C16/505 , C23C16/52 , C23C16/54 , G01N15/082 , G01N23/2273 , G01N30/7206 , G01N33/00 , G01N2033/0096 , Y10T428/13 , Y10T428/1383
摘要： Methods for processing a vessel, for example to provide a gas barrier or lubricity, are disclosed. First and second PECVD or other vessel processing stations or devices and a vessel holder comprising a vessel port are provided. An opening of the vessel can be seated on the vessel port. The interior surface of the seated vessel can be processed via the vessel port by the first and second processing stations or devices. Vessel barrier, lubricity and hydrophobic coatings and coated vessels, for example syringes and medical sample collection tubes are disclosed. A vessel processing system and vessel inspection apparatus and methods are also disclosed, for example using material outgassed from a surface to inspect the properties of a surface coating.
摘要翻译： 公开了处理容器的方法，例如提供阻气或润滑性。 提供第一和第二PECVD或其他容器加工站或装置以及包括容器端口的容器保持器。 船只的开口可以坐在船只港口上。 坐便器的内表面可以通过第一和第二处理站或设备经容器端口处理。 公开了船舶屏障，润滑性和疏水涂层以及涂覆的容器，例如注射器和医用样品收集管。 还公开了容器处理系统和容器检查装置和方法，例如使用从表面去除的材料来检查表面涂层的性质。
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公开(公告)号：US20150126941A1
公开(公告)日：2015-05-07
申请号：US14399678
申请日：2013-05-09
申请人： John T. Felts , Thomas E. Fisk , Robert S. Abrams , John Ferguson , Jonathan R. Freedman , Robert J. Pangborn , Peter Sagona , Christopher Weikart , Jacob Israelachvili
发明人： John T. Felts , Thomas E. Fisk , Robert S. Abrams , John Ferguson , Jonathan R. Freedman , Robert J. Pangborn , Peter Sagona , Christopher Weikart , Jacob Israelachvili
CPC分类号： A61J1/1468 , A61J1/00 , A61J1/05 , A61J1/2096 , A61J2200/50 , A61L31/10 , A61L2400/10 , A61L2420/08 , A61M3/0262 , Y10T428/1383
摘要： A method for providing a saccharide based lubricating or protective coating or layer on a substrate surface is provided. In particular, a lubricity and/or protective coating or layer made by said method is provided. Pharmaceutical packages or other vessels coated by said method and the use of such pharmaceutical packages or other vessels protecting a compound or composition contained or received in said vessel with a protective coating against mechanical and/or chemical effects of the surface of the vessel without a protective coating material are also provided.
摘要翻译： 提供了一种在基材表面上提供基于糖的润滑或保护涂层或层的方法。 特别地，提供了由所述方法制成的润滑性和/或保护性涂层或层。 通过所述方法涂覆的药物包装或其他容器以及使用这种药物包装或其他容器保护在所述容器中包含或接收的化合物或组合物的保护涂层，以防止容器表面的机械和/或化学作用而没有保护 还提供涂料。
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