A MODIFIED MICROORGANISM HAVING ENHANCED BIOMASS SYNTHESIS CAPACITY AND A METHOD THEREOF
    1.
    发明申请
    A MODIFIED MICROORGANISM HAVING ENHANCED BIOMASS SYNTHESIS CAPACITY AND A METHOD THEREOF 有权
    具有增强生物量合成能力的改性微生物及其方法

    公开(公告)号:US20160333358A1

    公开(公告)日:2016-11-17

    申请号:US15111554

    申请日:2015-02-04

    CPC classification number: C12N15/67 C07K14/395 C12N1/12 C12N15/79

    Abstract: The present disclosure provides a modified microorganism having an enhanced biomass synthesis capacity. The present disclosure also relates to a method for manufacturing a modified microorganism having an enhanced biomass synthesis capacity. The enhanced biomass synthesis capacity is due to the overexpression of the gene capable of inducing DNA repair mechanism. The gene responsible for the DNA repair is overexpressed when DNA damage is most and DNA repair mechanism is required.

    Abstract translation: 本公开提供了具有增强的生物质合成能力的经修饰的微生物。 本公开还涉及一种具有增强的生物质合成能力的修饰微生物的制造方法。 增强的生物质合成能力是由于能够诱导DNA修复机制的基因的过表达。 负责DNA修复的基因在DNA损伤最多且需要DNA修复机制时过表达。

    System, and a method for Algal Cultivation
    4.
    发明公开

    公开(公告)号:US20240060033A1

    公开(公告)日:2024-02-22

    申请号:US18451996

    申请日:2023-08-18

    Abstract: The present disclosure provides system (10) and a method for algal cultivation. The system for algal cultivation comprises a reservoir (1) which is configured to contain a fluid medium (6) having an algal culture; at least one circulating means (3) which is configured to circulate the fluid medium in the reservoir at a desired velocity; at least one covering means (5) which is configured in its operative configuration to at least partially cover an opening of the reservoir to at least partially block the light incident on the fluid medium and define intermittent light and dark cycle for the fluid medium for a predetermined period of time in the reservoir. Advantageously, the invention disclosed by the present disclosure improves biomass production, minimizes water evaporation in open pond system, avoids photo-inhibition or stress, provides optimum photosynthetic rate, provides efficient utilization of the space, provides efficient generation of resources such as renewable energy.

    METHOD OF INCREASING BIOMASS AND LIPID CONTENT IN A MICRO-ORGANISM AND A GENETICALLY MODIFIED MICRO-ORGANISM EXHIBITING ENHANCED AUTOPHAGY
    6.
    发明申请
    METHOD OF INCREASING BIOMASS AND LIPID CONTENT IN A MICRO-ORGANISM AND A GENETICALLY MODIFIED MICRO-ORGANISM EXHIBITING ENHANCED AUTOPHAGY 审中-公开
    微生物增加生物量和脂肪含量的方法和基因改良的微生物展示增强自动化

    公开(公告)号:US20160369307A1

    公开(公告)日:2016-12-22

    申请号:US15110683

    申请日:2015-01-09

    CPC classification number: C12P7/64 C07K14/405 C12N1/12 C12N15/8247

    Abstract: According to an embodiment of the invention, there is provided a method of increasing biomass and lipid content in a micro-organism comprising cloning in a vector an exogenous gene sequence selected from the group comprising Atg1 gene, Atg6 gene, and Atg8 gene sequence wherein the sequence is codon optimized for said micro-organism, for inducing autophagy; introducing the vector containing the gene into the genome of the micro-organism to yield a genetically modified micro-organism; and growing the genetically modified micro-organism in suitable medium. According to another embodiment of the invention there is provided a method of increasing biomass and lipid content in a micro-organism exposed to stress, comprising treating the microorganism with an autophagy inducing agent.

    Abstract translation: 根据本发明的一个实施方案,提供了一种增加微生物中生物量和脂质含量的方法,包括在载体中克隆选自Atg1基因,Atg6基因和Atg8基因序列的外源基因序列,其中 序列对于所述微生物进行密码子优化,用于诱导自噬; 将含有该基因的载体引入微生物的基因组以产生遗传修饰的微生物; 并在合适的培养基中生长转基因微生物。 根据本发明的另一个实施方案,提供了一种增加暴露于应激的微生物中的生物量和脂质含量的方法,包括用自噬诱导剂处理微生物。

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