-
公开(公告)号:US20120093378A1
公开(公告)日:2012-04-19
申请号:US13379668
申请日:2010-06-29
申请人: Rami Nachabé , Bernardus Hendrikus Wilhelmus Hendriks , Drazenko Babic , Augustinus Laurentius Braun , Marjolein Van Der Voort , Adrien Emmanuel Desjardins , Nenad Mihajlovic , Rik Harbers
发明人: Rami Nachabé , Bernardus Hendrikus Wilhelmus Hendriks , Drazenko Babic , Augustinus Laurentius Braun , Marjolein Van Der Voort , Adrien Emmanuel Desjardins , Nenad Mihajlovic , Rik Harbers
CPC分类号: A61B6/12 , A61B1/00147 , A61B5/065 , A61B6/463 , A61B6/5247 , A61B8/463 , A61B34/20 , A61B2034/256 , A61B2090/365
摘要: The invention relates to a medical imaging apparatus for providing information about an object. The invention further relates to a method for providing information about an object. In order to improve the preparation and the visual reception of information relating to an object during medical interventions, a medical imaging apparatus for providing information about an object is provided that comprises an image acquisition device an interventional device, a processing device and a display device. The image acquisition device detects object data from at least one region of interest of an object and provides the object data to the processing device. The interventional device detects physiological parameters of the object depending on the position of a predetermined area of the interventional device in relation to the object and provides the physiological parameters to the processing device. Further, the processing device transforms at least a part of the object data into image data and converts the physiological parameters into physiological data. The processing device then modifies at least one image parameter of the image data depending on the physiological data and thereby transforms the image data into modified live image data which is provided to the display device displaying a modified live image.
摘要翻译: 本发明涉及一种用于提供关于物体的信息的医学成像设备。 本发明还涉及一种用于提供关于对象的信息的方法。 为了改善在医疗干预期间与物体有关的信息的准备和视觉接收,提供了一种用于提供关于物体的信息的医学成像装置,其包括图像获取装置,介入装置,处理装置和显示装置。 图像获取装置从对象的至少一个感兴趣区域检测对象数据,并将对象数据提供给处理装置。 介入装置根据介入装置相对于物体的预定区域的位置来检测物体的生理参数,并将生理参数提供给处理装置。 此外,处理装置将至少一部分对象数据变换为图像数据,并将生理参数转换为生理数据。 处理装置然后根据生理数据修改图像数据的至少一个图像参数,从而将图像数据变换为提供给显示修改的实时图像的显示装置的修改的实况图像数据。
-
公开(公告)号:US20110218445A1
公开(公告)日:2011-09-08
申请号:US13129206
申请日:2009-06-15
申请人: Augustinus Laurentius Braun , Bernardus Hendrikus Wilhelmus Hendriks , Rik Harbers , Marjolein Van Der Voort , Adrien Emmanuel Desjardins , Rami Nachabe , Bernardus Wilhelmus Johannes Wassink , Franciscus Marinus Antonius Maria Van Gaal , Nenad Mihajlovic , Drazenko Babic
发明人: Augustinus Laurentius Braun , Bernardus Hendrikus Wilhelmus Hendriks , Rik Harbers , Marjolein Van Der Voort , Adrien Emmanuel Desjardins , Rami Nachabe , Bernardus Wilhelmus Johannes Wassink , Franciscus Marinus Antonius Maria Van Gaal , Nenad Mihajlovic , Drazenko Babic
CPC分类号: A61B5/6848 , A61B5/0075 , A61B5/0084
摘要: Needles equipped with fibres allow tissue inspection based on optical spectroscopy to diagnose whether tissue is cancerous or not. This requires integration of optical fibers into needles. The problem is how to manufacture the needle having at least one fiber exit at the distal end of the needle, where the fiber does not obstruct the hollow part of the needle if present as well as does not extend beyond the outer cylinder geometry. To solve this problem we propose to manufacture the needle consisting of four parts: an inner cylinder tube, an outer hollow cylinder tube, a needle tip part with integrated fiber exit and a holder part, wherein the hollow spacing between the inner and the outer cylinder is larger or equal to the outer diameter of the fibers, the inner and the outer cylinder are mounted in the holder part and where the tip part is mounted on the two cylinders.
摘要翻译: 配备纤维的针头允许基于光谱的组织检查来诊断组织是否是癌变的。 这需要将光纤集成到针中。 问题是如何制造在针的远端具有至少一个纤维出口的针,其中纤维不会阻塞针的中空部分,如果存在,并且不延伸超出外筒几何形状。 为了解决这个问题,我们建议制造由四部分组成的针:内筒管,外空心筒管,具有集成纤维出口的针尖部分和保持器部分,其中内筒和外筒之间的中空间隔 大于或等于纤维的外径,内筒和外筒安装在保持器部分中,并且尖端部分安装在两个气缸上。
-
公开(公告)号:US08812080B2
公开(公告)日:2014-08-19
申请号:US13376702
申请日:2010-06-07
申请人: Rami Nachabe , Bernardus Hendrikus Wilhelmus Hendriks , Augustinus Laurentius Braun , Marjolein Van Der Voort , Adrien Desjardins , Drazenko Babic , Nenad Mihajlovic
发明人: Rami Nachabe , Bernardus Hendrikus Wilhelmus Hendriks , Augustinus Laurentius Braun , Marjolein Van Der Voort , Adrien Desjardins , Drazenko Babic , Nenad Mihajlovic
IPC分类号: A61B5/05
CPC分类号: G06F19/321 , A61B5/0066 , A61B5/0071 , A61B5/0075 , A61B5/0084 , A61B5/0091 , A61B5/14503 , A61B5/6848 , A61B5/7435 , A61B5/7475 , A61B6/467 , A61B6/469 , A61B6/545 , A61B8/0833 , A61B8/461 , A61B8/467 , A61B8/469 , A61B8/585 , A61B17/3401 , A61B17/3403 , A61B34/20 , A61B90/92 , A61B90/96 , A61B90/98 , A61B2017/00199 , A61B2017/00225 , A61B2034/2055 , A61B2090/376 , A61B2090/3908 , A61B2090/3945 , A61B2562/08 , G06F19/00 , G16H40/63
摘要: Needles are widely used in interventional radiology. Each medical application requires a specific needle type. The same holds for the photonic needles which analysis depends on the type of application the clinician aims for. Therefore, it is relevant to have the X-ray machine recognize the type of needle that is being used and to load the required software for the tissue analysis. It is therefore proposed to have a data link established between the imaging modality used for the acquisition of the patient anatomy (X-ray, CT, MR or US) and the system that processes optical data from the needle, so that the information from this imaging modality can be used to guide the processing. In a preferred embodiment the selection is made by reading out the code present in the disposable needle when it is connected to the console.
摘要翻译: 针头广泛用于介入放射学。 每个医疗应用都需要特殊的针型。 同样适用于光子针,分析取决于临床医生的应用类型。 因此,使X射线机器识别正在使用的针的类型并加载组织分析所需的软件是相关的。 因此,建议在用于获取患者解剖结构(X射线,CT,MR或US)的成像模式和处理来自针的光学数据的系统之间建立数据链路,使得来自该信息的信息 成像模式可用于指导处理。 在优选实施例中,通过在连接到控制台时读出一次性针头中存在的代码来进行选择。
-
公开(公告)号:US20120088991A1
公开(公告)日:2012-04-12
申请号:US13376702
申请日:2010-06-07
申请人: Rami Nachabe , Bernardus Hendrikus Wilhelmus Hendriks , Augustinus Laurentius Braun , Marjolein Van Der Voort , Adrien Desjardins , Drazenko Babic , Nenad Mihajlovic
发明人: Rami Nachabe , Bernardus Hendrikus Wilhelmus Hendriks , Augustinus Laurentius Braun , Marjolein Van Der Voort , Adrien Desjardins , Drazenko Babic , Nenad Mihajlovic
IPC分类号: A61B5/1455 , A61B5/055 , A61B5/05
CPC分类号: G06F19/321 , A61B5/0066 , A61B5/0071 , A61B5/0075 , A61B5/0084 , A61B5/0091 , A61B5/14503 , A61B5/6848 , A61B5/7435 , A61B5/7475 , A61B6/467 , A61B6/469 , A61B6/545 , A61B8/0833 , A61B8/461 , A61B8/467 , A61B8/469 , A61B8/585 , A61B17/3401 , A61B17/3403 , A61B34/20 , A61B90/92 , A61B90/96 , A61B90/98 , A61B2017/00199 , A61B2017/00225 , A61B2034/2055 , A61B2090/376 , A61B2090/3908 , A61B2090/3945 , A61B2562/08 , G06F19/00 , G16H40/63
摘要: Needles are widely used in interventional radiology. Each medical application requires a specific needle type. The same holds for the photonic needles which analysis depends on the type of application the clinician aims for. Therefore, it is relevant to have the X-ray machine recognize the type of needle that is being used and to load the required software for the tissue analysis. It is therefore proposed to have a data link established between the imaging modality used for the acquisition of the patient anatomy (X-ray, CT, MR or US) and the system that processes optical data from the needle, so that the information from this imaging modality can be used to guide the processing. In a preferred embodiment the selection is made by reading out the code present in the disposable needle when it is connected to the console.
摘要翻译: 针头广泛用于介入放射学。 每个医疗应用都需要特殊的针型。 同样适用于光子针,分析取决于临床医生的应用类型。 因此,使X射线机器识别正在使用的针的类型并加载组织分析所需的软件是相关的。 因此,建议在用于获取患者解剖结构(X射线,CT,MR或US)的成像模式和处理来自针的光学数据的系统之间建立数据链路,使得来自该信息的信息 成像模式可用于指导处理。 在优选实施例中,通过在连接到控制台时读出一次性针头中存在的代码来进行选择。
-
公开(公告)号:US20120113491A1
公开(公告)日:2012-05-10
申请号:US13320601
申请日:2010-05-10
申请人: Cornelius Antonius Hezemans , Bernardus Hendrikus Wilhelmus Hendriks , Waltherus Cornelis Jozef Bierhoff , Augustinus Laurentius Braun , Nenad Mihajlovic
发明人: Cornelius Antonius Hezemans , Bernardus Hendrikus Wilhelmus Hendriks , Waltherus Cornelis Jozef Bierhoff , Augustinus Laurentius Braun , Nenad Mihajlovic
IPC分类号: G02B26/10
CPC分类号: A61B5/6848 , A61B5/0068 , A61B5/0084 , G02B21/0012 , G02B21/0036 , G02B23/2423 , G02B23/26 , G02B26/103
摘要: The present invention relates to an optical probe (1) suitable for miniature applications. An example application is a fibre-based confocal miniaturized microscope. The optical probe comprises a coil-based actuation system (9, 10) comprising drive coils (9) capable of displacing the distal end (3) of an optical guide (2) housed (4) by the optical probe. The probe makes use of a feedback loop which alternate between driving the displacement of the optical guide by driving a current through the drive coils and switching off the current through the drive coils, and while the drive current being switched off, measure the speed of the distal end of the optical guide. The measured speed is compared to the set-point speed, and if a difference is detected, the drive current is adjusted to eliminate, or at least bring down, this difference.
摘要翻译: 本发明涉及适合于微型应用的光学探头(1)。 一个示例应用是基于光纤的共聚焦微型显微镜。 光探头包括基于线圈的致动系统(9,10),其包括驱动线圈(9),该驱动线圈能够移动由光学探头容纳(4)的光导(2)的远端(3)。 探头利用反馈回路,通过驱动通过驱动线圈的电流驱动光导的位移和切断通过驱动线圈的电流之间的交替,并且在驱动电流被切断时,测量速度 光导的远端。 将测量的速度与设定点速度进行比较,并且如果检测到差异,则调节驱动电流以消除或至少降低该差异。
-
公开(公告)号:US08717654B2
公开(公告)日:2014-05-06
申请号:US13320601
申请日:2010-05-10
申请人: Cornelius Antonius Hezemans , Bernardus Hendrikus Wilhelmus Hendriks , Waltherus Cornelis Jozef Bierhoff , Augustinus Laurentius Braun , Nenad Mihajlovic
发明人: Cornelius Antonius Hezemans , Bernardus Hendrikus Wilhelmus Hendriks , Waltherus Cornelis Jozef Bierhoff , Augustinus Laurentius Braun , Nenad Mihajlovic
CPC分类号: A61B5/6848 , A61B5/0068 , A61B5/0084 , G02B21/0012 , G02B21/0036 , G02B23/2423 , G02B23/26 , G02B26/103
摘要: The present invention relates to an optical probe (1) suitable for miniature applications. An example application is a fiber-based confocal miniaturized microscope. The optical probe comprises a coil-based actuation system (9, 10) comprising drive coils (9) capable of displacing the distal end (3) of an optical guide (2) housed (4) by the optical probe. The probe makes use of a feedback loop which alternate between driving the displacement of the optical guide by driving a current through the drive coils and switching off the current through the drive coils, and while the drive current being switched off, measure the speed of the distal end of the optical guide. The measured speed is compared to the set-point speed, and if a difference is detected, the drive current is adjusted to eliminate, or at least bring down, this difference.
摘要翻译: 本发明涉及适合于微型应用的光学探头(1)。 一个示例应用是基于光纤的共聚焦微型显微镜。 光探头包括基于线圈的致动系统(9,10),其包括驱动线圈(9),该驱动线圈能够移动由光学探头容纳(4)的光导(2)的远端(3)。 探头利用反馈回路,通过驱动通过驱动线圈的电流驱动光导的位移和切断通过驱动线圈的电流之间的交替,并且当驱动电流被切断时,测量速度 光导的远端。 将测量的速度与设定点速度进行比较,并且如果检测到差异,则调节驱动电流以消除或至少降低该差异。
-
公开(公告)号:US20130050683A1
公开(公告)日:2013-02-28
申请号:US13641894
申请日:2011-04-11
申请人: Bernardus Hendrikus Wilhelmus Henrdiks , Gerhardus Wilhelmus Lucassen , Rami Nachabe , Nenad Mihajlovic , Adrien Emmanuel Desjardins , Jeroen Jan Lambertus Horikx , Marjolein Van Der Voort
发明人: Bernardus Hendrikus Wilhelmus Henrdiks , Gerhardus Wilhelmus Lucassen , Rami Nachabe , Nenad Mihajlovic , Adrien Emmanuel Desjardins , Jeroen Jan Lambertus Horikx , Marjolein Van Der Voort
CPC分类号: A61B5/0075 , A61B5/0062 , A61B5/0071 , A61B5/0084 , A61B5/6848
摘要: The present invention relates to a system for extending microscopy information, where the microscopy information is image information from a first region (118) of an associated sample, the first region being imaged with an imaging system. The extension of the microscopy information originates from probing a larger second region (116) by photons which are emitted at an exit position (128) and collected at en entry position (130). The exit position and the entry position are spatially separated so that so that average spectral information of photons emitted from the exit position and collected at the entry position, is dependent on the second region (116) of the associated sample, the second region (116) being larger than the first region (118).
摘要翻译: 本发明涉及用于扩展显微镜信息的系统,其中显微镜信息是来自相关样品的第一区域(118)的图像信息,第一区域用成像系统成像。 显微镜信息的延伸来自于在出口位置(128)处发射并在入口位置(130)收集的光子探测较大的第二区域(116)。 出口位置和入口位置在空间上分离,使得从出口位置发射并在入口位置收集的光子的平均光谱信息取决于相关样品的第二区域(116),第二区域(116) )大于第一区域(118)。
-
公开(公告)号:US20100282954A1
公开(公告)日:2010-11-11
申请号:US12810523
申请日:2008-12-22
申请人: Bernardus Hendrikus Wilhelmus Hendriks , Waltherus Cornelis Jozef Bierhoff , Augustinus Laurentius Braun , Nenad Mihajlovic , Gert 'T Hooft
发明人: Bernardus Hendrikus Wilhelmus Hendriks , Waltherus Cornelis Jozef Bierhoff , Augustinus Laurentius Braun , Nenad Mihajlovic , Gert 'T Hooft
CPC分类号: A61B5/0062 , A61B1/00096 , A61B1/00165 , A61B1/00183 , A61B1/0019 , A61B5/0084
摘要: The present invention relates to an optical probe (1) with an optical guide (2), e.g. an optical fibre, and a lens system (6) rigidly coupled to an end portion (2a) of the optical guide. The probe has a housing (3) with a cavity for the optical guide, the housing having at its distal end a transparent window (4), the window having an insignificant optical power as compared to the optical power of the said lens system (6). Actuation means (8) displaces the 5 lens system so as to enable optical scanning of a region of interest (ROI). The invention is particularly suited for miniature applications e.g. for in-vivo medical application. By attaching the lens system (6) to the optical guide (2) via the mount (7), the field of view (FOV) of the optical probe (1) may be determined directly by the transverse stroke of the optical fibre (2). Hence only a relatively small stroke is required. The field of view is thus 10 effectively no longer limited by the transverse stroke. The optical probe is especially advantageous for non-linear optical imaging where the optical guide may be an optical fibre with a relatively low exit numerical aperture.
摘要翻译: 本发明涉及一种具有光导(2)的光学探针(1),例如, 光纤,以及刚性地耦合到光导的端部(2a)的透镜系统(6)。 该探针具有一个具有用于光导的空腔的壳体(3),该壳体在其远端处具有透明窗口(4),该窗口与所述透镜系统(6)的光焦度相比具有无效的光焦度 )。 驱动装置(8)使5透镜系统移位,以便对感兴趣区域(ROI)进行光学扫描。 本发明特别适用于微型应用,例如 用于体内医疗应用。 通过经由安装件(7)将透镜系统(6)附接到光导(2),光学探头(1)的视场(FOV)可以直接由光纤(2)的横向行程确定 )。 因此,只需要相对较小的行程。 因此,视场10不再受横向行程的限制。 光学探头对于非线性光学成像特别有利,其中光导可以是具有相对低的出射数值孔径的光纤。
-
公开(公告)号:US20110118610A1
公开(公告)日:2011-05-19
申请号:US13002990
申请日:2009-07-03
IPC分类号: A61B6/00
摘要: The invention relates to an optical image probe(20) for particularly suited for miniature application e.g. in-vivo. A fluid lens(5) is positioned a housing (19),the fluid lens having a changeable optical power. An image collector (40) is positioned within the housing, the collector being arranged on an optical path of the fluid lens, the collector being displaceable along the said optical path by an actuator (42, 70, 80, 90) in various ways. It is highly advantageous in obtaining a compact optical image probe and which simultaneously has a high zoom factor. Due the possible displacement of the image collector and the changeable optical power of the fluid lens, and cooperation between these two elements, it is possible to obtain a compact endoscope with a wide dynamic range of zoom factor with satisfactory focusing properties.
摘要翻译: 本发明涉及一种特别适用于微型应用的光学图像探针(20)。 体内。 液体透镜(5)定位在壳体(19)上,流体透镜具有可变光学功率。 图像收集器(40)定位在壳体内,集电器布置在流体透镜的光路上,集电器可以通过致动器(42,70,80,90)以各种方式沿着所述光路移动。 在获得紧凑型光学图像探针并且同时具有高变焦系数方面是非常有利的。 由于图像收集器的可能位移和流体透镜的可变光学功率以及这两个元件之间的协调,可以获得具有良好聚焦性能的宽动态范围的变焦系数的紧凑型内窥镜。
-
公开(公告)号:US20100188368A1
公开(公告)日:2010-07-29
申请号:US12667059
申请日:2008-06-30
申请人: Cristian Presura , Jan Frederik Suijver , Bernardus Hendrikus Wilhelmus Hendriks , Nenad Mihajlovic , Galileo June Destura
发明人: Cristian Presura , Jan Frederik Suijver , Bernardus Hendrikus Wilhelmus Hendriks , Nenad Mihajlovic , Galileo June Destura
IPC分类号: G06F3/042
CPC分类号: G06F3/0321 , G06F3/03545
摘要: Touch screen capabilities are added to a color display (10), such as an LCD display with backlighting. Thereto, the wavelength is varied in two color channels along the horizontal (x) and vertical (z) directions. A pen (30) having spectroscopic capabilities incorporated in it for the two relevant colors determines its position by measuring the wavelengths of the two channels.
摘要翻译: 触摸屏功能被添加到彩色显示器(10),例如具有背光的LCD显示器。 此外,波长沿着水平(x)和垂直(z)方向在两个颜色通道中变化。 具有并入其中的两种相关颜色的具有光谱能力的笔(30)通过测量两个通道的波长来确定其位置。
-
-
-
-
-
-
-
-
-