公开(公告)号：US4911837A

公开(公告)日：1990-03-27

申请号：US339473

申请日：1989-04-17

申请人： Robert W. Allington ,  Yoossef Tehrani ,  John N. Jones

发明人： Robert W. Allington ,  Yoossef Tehrani ,  John N. Jones

IPC分类号： B01D15/08 ,  B01D15/22 ,  G01N30/60 ,  G01N30/74

CPC分类号： B01D15/22 ,  G01N30/603 ,  G01N30/6017 ,  G01N30/6026 ,  G01N30/6052 ,  G01N30/74

摘要： To reduce tailing, the frit at the outlet to the liquid chromatographic column has a diameter substantially equal to that of the inside diameter of the outlet end of the column and less than two millimeters. It is held directly against the packing of the column within a cylindrical member having a shoulder with a central aperture at least the size of the diameter of the frit and cylindrical walls which are fastened to resist force in the direction of the axis of the column from its inlet to its outlet. A gasket seals the cylindrical holder against the column wall. The frit is formed of gold-plated nickel spheres sintered together at a temperature lower than the gold-nickel eutectic temperature of 950 degrees Celsius but above the phase-immiscibility temperature of 720 degrees Celsius. The size and shape of the frit is selected to reduce tailing by causing the flow path from the column to be uniform.

摘要翻译： 为了减少拖尾，液相色谱柱出口处的玻璃料的直径基本上等于柱的出口端的内径，直径小于2毫米。 它被直接抵靠在具有肩部的圆柱形构件的圆柱形构件中，所述圆柱形构件具有至少具有中心孔的至少大小的玻璃料和圆柱形壁的直径的尺寸，所述玻璃料和圆柱形壁被紧固以抵抗在柱的轴线方向上的力 其入口到其出口。 垫圈将柱形保持器密封在柱壁上。 玻璃料由在950℃以下的金 - 镍共晶温度下高于720℃的相互不混溶温度的温度下烧结在一起的镀金镍球形成。 选择玻璃料的尺寸和形状以通过使来自塔的流动路径均匀来减少拖尾。

公开(公告)号：US06294088B1

公开(公告)日：2001-09-25

申请号：US09713895

申请日：2000-11-16

申请人： Robert W. Allington ,  Henry LeRoy Walters ,  Daniel Gene Jameson ,  Yoossef Tehrani

发明人： Robert W. Allington ,  Henry LeRoy Walters ,  Daniel Gene Jameson ,  Yoossef Tehrani

IPC分类号： B01D1508

CPC分类号： B01D11/0407 ,  B01D11/0203 ,  F04B9/042 ,  F04B15/08 ,  F04B49/065 ,  F04B2205/03 ,  F04B2205/05 ,  F04B2205/09 ,  F05B2230/41 ,  F05C2201/0493 ,  F05C2253/12 ,  F16K15/183 ,  G01F1/34 ,  G01N1/34 ,  G01N1/40 ,  G01N30/02 ,  G01N30/28 ,  G01N30/32 ,  G01N30/60 ,  G01N30/82 ,  G01N2001/4033 ,  G01N2001/4061 ,  G01N2030/6008 ,  G01N2030/6013 ,  G01N2035/0441 ,  G21F5/015 ,  B01D15/40

摘要： A variable-orifice fluid restrictor for use with a supercritical extractor or chromatograph includes an inlet line for fluid at a pressure above its critical pressure, an extended tubular probe having an inner and an outer surface and a proximal and a distal end. The proximal end of the probe is disposed toward the inlet line. The distal end of the probe includes an adjustable orifice means adapted for metering the fluid and having first and second orifice members and an adjusting stem having first and second ends. The adjustable orifice means is adjacent to the outer surface of the probe and the orifice means is adjustable with the adjusting stem. The end of the adjusting stem is located at the distal end of the probe and is adapted for moving the first orifice member with respect to the second orifice member to control the adjustable orifice for varying the restriction of fluid passing through the adjustable orifice. The distal end of the probe is inside the collector and the adjusting stem extends outside of the collector.

摘要翻译： 用于超临界萃取器或色谱仪的可变孔口流体限制器包括用于在高于其临界压力的压力下的流体的入口管线，具有内外表面和近端和远端的延伸管状探针。 探针的近端朝向入口线设置。 探针的远端包括适于计量流体并具有第一和第二孔口构件的调节孔口装置和具有第一和第二端部的调节杆。 可调整的孔口装置与探针的外表面相邻，孔口装置可用调节杆调节。 调节杆的端部位于探针的远端，并且适于相对于第二孔构件移动第一孔构件以控制可调节孔，以改变通过可调节孔的流体的限制。 探针的远端位于收集器内部，调节杆延伸到收集器外部。

公开(公告)号：US5635070A

公开(公告)日：1997-06-03

申请号：US208121

申请日：1994-03-08

申请人： Robert W. Allington ,  Daniel G. Jameson ,  Dale A. Davison ,  Dale Clay ,  Robin R. Winter ,  Yoossef Tehrani

发明人： Robert W. Allington ,  Daniel G. Jameson ,  Dale A. Davison ,  Dale Clay ,  Robin R. Winter ,  Yoossef Tehrani

IPC分类号： B01D11/00 ,  B01D11/02 ,  B01D11/04 ,  F04B9/04 ,  F04B15/08 ,  F04B49/06 ,  F04B53/08 ,  F04B53/14 ,  F16K15/18 ,  G01F1/34 ,  G01N1/34 ,  G01N1/40 ,  G01N30/02 ,  G01N30/28 ,  G01N30/60 ,  G01N35/04 ,  G21F5/015

CPC分类号： G01N1/34 ,  B01D11/0203 ,  B01D11/0407 ,  F04B15/08 ,  F04B49/065 ,  F04B53/08 ,  F04B53/143 ,  F04B9/042 ,  F16K15/183 ,  G01F1/34 ,  G01N1/40 ,  G01N30/28 ,  G21F5/015 ,  F04B2201/0209 ,  F04B2205/03 ,  F04B2205/05 ,  F04B2205/09 ,  F05B2230/41 ,  F05C2201/0493 ,  F05C2253/12 ,  G01N2001/4033 ,  G01N2001/4061 ,  G01N2030/6013 ,  G01N2035/0441 ,  G01N30/02

摘要： To pump supercritical carbon dioxide into a supercritical extractor without overpressure in the reservoir and to record the volume being delivered, the pumping speed is controlled and the volume pumped is determined from a pressure-related signal used in a feedback circuit. The feedback controls the velocity of pumping in conjunction with programmed values to avoid destructive reverse torque. A cam in the pump controls piston stroke, has a depressurization portion with an initial slope equal to but in the opposite direction of the final slope, rounded transition slopes, increasing linear velocity to the refill portion and constant velocity in the refill portion.

公开(公告)号：US5614089A

公开(公告)日：1997-03-25

申请号：US542683

申请日：1995-10-13

申请人： Robert W. Allington ,  Henry L. Walters ,  Daniel G. Jameson ,  Yoossef Tehrani

发明人： Robert W. Allington ,  Henry L. Walters ,  Daniel G. Jameson ,  Yoossef Tehrani

IPC分类号： B01D11/02 ,  B01D11/04 ,  F04B9/04 ,  F04B15/08 ,  F04B49/06 ,  F16K15/18 ,  G01F1/34 ,  G01N1/34 ,  G01N1/40 ,  G01N30/02 ,  G01N30/28 ,  G01N30/32 ,  G01N30/60 ,  G01N30/82 ,  G01N35/04 ,  G21F5/015 ,  B01D15/08

CPC分类号： B01D11/0407 ,  B01D11/0203 ,  F04B15/08 ,  F04B49/065 ,  F04B9/042 ,  F16K15/183 ,  G01F1/34 ,  G01N1/34 ,  G01N1/40 ,  G01N30/28 ,  G01N30/82 ,  G21F5/015 ,  F04B2205/03 ,  F04B2205/05 ,  F04B2205/09 ,  F05B2230/41 ,  F05C2201/0493 ,  F05C2253/12 ,  G01N2001/4033 ,  G01N2001/4061 ,  G01N2030/6008 ,  G01N2030/6013 ,  G01N2035/0441 ,  G01N30/02 ,  G01N30/32 ,  G01N30/60

摘要： A variable-orifice fluid restrictor for use with a supercritical extractor or chromatograph includes an inlet line for fluid at a pressure above its critical pressure, an extended tubular probe having an inner and an outer surface and a proximal and a distal end. The proximal end of the probe is disposed toward the inlet line. The distal end of the probe includes an adjustable orifice means adapted for metering the fluid and having first and second orifice members and an adjusting stem having first and second ends. The adjustable orifice means is adjacent to the outer surface of the probe and the orifice means is adjustable with the adjusting stem. The end of the adjusting stem is located at the distal end of the probe and is adapted for moving the first orifice member with respect to the second orifice member to control the adjustable orifice for varying the restriction of fluid passing through the adjustable orifice.

摘要翻译： 用于超临界萃取器或色谱仪的可变孔口流体限制器包括用于高于其临界压力的压力的流体的入口管线，具有内外表面和近端和远端的延伸管状探针。 探针的近端朝向入口线设置。 探针的远端包括适于计量流体并具有第一和第二孔口构件的调节孔口装置和具有第一和第二端部的调节杆。 可调整的孔口装置与探针的外表面相邻，孔口装置可用调节杆调节。 调节杆的端部位于探针的远端，并且适于相对于第二孔构件移动第一孔构件以控制可调节孔，以改变通过可调节孔的流体的限制。

公开(公告)号：US6149814A

公开(公告)日：2000-11-21

申请号：US74254

申请日：1998-05-07

申请人： Robert W. Allington ,  Henry LeRoy Walters ,  Daniel Gene Jameson ,  Yoossef Tehrani

发明人： Robert W. Allington ,  Henry LeRoy Walters ,  Daniel Gene Jameson ,  Yoossef Tehrani

IPC分类号： B01D11/02 ,  B01D11/04 ,  F04B9/04 ,  F04B15/08 ,  F04B49/06 ,  F16K15/18 ,  G01F1/34 ,  G01N1/34 ,  G01N1/40 ,  G01N30/02 ,  G01N30/28 ,  G01N30/32 ,  G01N30/60 ,  G01N30/82 ,  G01N35/04 ,  G21F5/015 ,  B01D11/00

CPC分类号： B01D11/0407 ,  B01D11/0203 ,  F04B15/08 ,  F04B49/065 ,  F04B9/042 ,  F16K15/183 ,  G01F1/34 ,  G01N1/34 ,  G01N1/40 ,  G01N30/28 ,  G01N30/82 ,  G21F5/015 ,  F04B2205/03 ,  F04B2205/05 ,  F04B2205/09 ,  F05B2230/41 ,  F05C2201/0493 ,  F05C2253/12 ,  G01N2001/4033 ,  G01N2001/4061 ,  G01N2030/6008 ,  G01N2030/6013 ,  G01N2035/0441 ,  G01N30/02 ,  G01N30/32 ,  G01N30/60

摘要： A variable-orifice fluid restrictor for use with a supercritical extractor or chromatograph includes an inlet line for fluid at a pressure above its critical pressure, an extended tubular probe having an inner and an outer surface and a proximal and a distal end. The proximal end of the probe is disposed toward the inlet line. The distal end of the probe includes an adjustable orifice means adapted for metering the fluid and having first and second orifice members and an adjusting stem having first and second ends. The adjustable orifice means is adjacent to the outer surface of the probe and the orifice means is adjustable with the adjusting stem. The end of the adjusting stem is located at the distal end of the probe and is adapted for moving the first orifice member with respect to the second orifice member to control the adjustable orifice for varying the restriction of fluid passing through the adjustable orifice.

摘要翻译： 用于超临界萃取器或色谱仪的可变孔口流体限制器包括用于高于其临界压力的压力的流体的入口管线，具有内外表面和近端和远端的延伸管状探针。 探针的近端朝向入口线设置。 探针的远端包括适于计量流体并具有第一和第二孔口构件的调节孔口装置和具有第一和第二端部的调节杆。 可调整的孔口装置与探针的外表面相邻，孔口装置可用调节杆调节。 调节杆的端部位于探针的远端，并且适于相对于第二孔构件移动第一孔构件以控制可调节孔，以改变通过可调节孔的流体的限制。

公开(公告)号：US5750027A

公开(公告)日：1998-05-12

申请号：US804682

申请日：1997-02-25

申请人： Robert W. Allington ,  Henry LeRoy Walters ,  Daniel Gene Jameson ,  Yoossef Tehrani

发明人： Robert W. Allington ,  Henry LeRoy Walters ,  Daniel Gene Jameson ,  Yoossef Tehrani

IPC分类号： B01D11/02 ,  B01D11/04 ,  F04B9/04 ,  F04B15/08 ,  F04B49/06 ,  F16K15/18 ,  G01F1/34 ,  G01N1/34 ,  G01N1/40 ,  G01N30/02 ,  G01N30/28 ,  G01N30/32 ,  G01N30/60 ,  G01N30/82 ,  G01N35/04 ,  G21F5/015

CPC分类号： B01D11/0407 ,  B01D11/0203 ,  F04B15/08 ,  F04B49/065 ,  F04B9/042 ,  F16K15/183 ,  G01F1/34 ,  G01N1/34 ,  G01N1/40 ,  G01N30/28 ,  G01N30/82 ,  G21F5/015 ,  F04B2205/03 ,  F04B2205/05 ,  F04B2205/09 ,  F05B2230/41 ,  F05C2201/0493 ,  F05C2253/12 ,  G01N2001/4033 ,  G01N2001/4061 ,  G01N2030/6008 ,  G01N2030/6013 ,  G01N2035/0441 ,  G01N30/02 ,  G01N30/32 ,  G01N30/60

摘要： A variable-orifice fluid restrictor for use with a supercritical extractor or chromatograph includes an inlet line for fluid at a pressure above its critical pressure, an extended tubular probe having an inner and an outer surface and a proximal and a distal end. The proximal end of the probe is disposed toward the inlet line. The distal end of the probe includes an adjustable orifice means adapted for metering the fluid and having first and second orifice members and an adjusting stem having first and second ends. The adjustable orifice means is adjacent to the outer surface of the probe and the orifice means is adjustable with the adjusting stem. The end of the adjusting stem is located at the distal end of the probe and is adapted for moving the first orifice member with respect to the second orifice member to control the adjustable orifice for varying the restriction of fluid passing through the adjustable orifice.

公开(公告)号：US5080785A

公开(公告)日：1992-01-14

申请号：US523475

申请日：1990-05-15

申请人： Robert W. Allington ,  John N. Jones

发明人： Robert W. Allington ,  John N. Jones

IPC分类号： G01N30/34

CPC分类号： G01N30/34

摘要： To prevent the solvents forming a gradient from mixing at the wrong place and to provide for accurate composition at start of the gradient in spite of solvent pressure variations, a microliquid or supercritical fluid chromatograph includes a combined mixer and pressure detector in which equal pressures of the two solvents in the gradient are detected by displacement of a ferromagnetic poppet in the mixing chamber. The poppet serves as a stop for the final solvent until the pressures are substantially equal and then its movement is detected by a circuit related to a linear variable differential transformer. The signal energizes a circuit which drives one of the sensing coils to drive the poppet during the gradient to provide mixing.

摘要翻译： 为了防止形成梯度的溶剂在错误的地方混合，并且尽管有溶剂压力变化而在梯度开始时提供精确的组成，但微液体或超临界流体色谱仪包括组合的混合器和压力检测器，其中相同的压力 梯度中的两种溶剂通过在混合室中的铁磁提升阀的位移来检测。 提升阀作为最终溶剂的停止点，直到压力基本相等，然后通过与线性可变差动变压器相关的电路检测其运动。 该信号激励驱动其中一个感测线圈的电路，以在梯度期间驱动提升阀以提供混合。

公开(公告)号：US5071562A

公开(公告)日：1991-12-10

申请号：US621648

申请日：1990-12-03

申请人： Robert W. Allington ,  John N. Jones

发明人： Robert W. Allington ,  John N. Jones

IPC分类号： G01N30/34

CPC分类号： G01N30/34

摘要： To prevent the solvents forming a gradient from mixing at the wrong place and to provide for accurate composition at start of the gradient in spite of solvent pressure variations, a microliquid or supercritical fluid chromatograph includes a combined mixer and pressure detector in which equal pressures of the two solvents in the gradient are detected by displacement of a ferromagnetic poppet in the mixing chamber. The poppet serves as a stop for the final solvent until the pressures are substantially equal and then its movement is detected by a circuit related to a linear variable differential transformer. The signal energizes a circuit which drives one of the sensing coils to drive the poppet during the gradient to provide mixing.

摘要翻译： 为了防止形成梯度的溶剂在错误的地方混合，并且尽管有溶剂压力变化而在梯度开始时提供精确的组成，但微液体或超临界流体色谱仪包括组合的混合器和压力检测器，其中相同的压力 梯度中的两种溶剂通过在混合室中的铁磁提升阀的位移来检测。 提升阀作为最终溶剂的停止点，直到压力基本相等，然后通过与线性可变差动变压器相关的电路检测其运动。 该信号激励驱动其中一个感测线圈的电路，以在梯度期间驱动提升阀以提供混合。

公开(公告)号：US4966696A

公开(公告)日：1990-10-30

申请号：US368112

申请日：1989-06-16

申请人： Robert W. Allington ,  Abolghassem Y. Tehrani ,  John N. Jones

发明人： Robert W. Allington ,  Abolghassem Y. Tehrani ,  John N. Jones

IPC分类号： B01D15/08 ,  B01D15/22 ,  G01N30/60 ,  G01N30/74

CPC分类号： B01D15/22 ,  G01N30/603 ,  G01N30/6017 ,  G01N30/6026 ,  G01N30/6052 ,  G01N30/74

摘要： To reduce tailing, the frit at the outlet to the liquid chromatographic column has a diameter substantially equal to that of the inside diameter of the outlet end of the column and less than two millimeters. It is held directly against the packing of the column within a cylindrical member having a shoulder with a central aperture at least the size of the diameter of the frit and cylindrical walls which are fastened to resist force in the direction of the axis of the column from its inlet to its outlet. A gasket seals the cylindrical holder against the column wall. The frit is formed of gold-plated nickel spheres sintered together at temperature lower than the gold-nickel eutectic temperature of 950 degrees Celsius but above the phase-immiscibility temperature of 720 degrees Celsius. The size and shape of the frit is selected to reduce tailing by causing the flow path from the column to be uniform.

摘要翻译： 为了减少拖尾，液相色谱柱出口处的玻璃料的直径基本上等于柱的出口端的内径，直径小于2毫米。 它被直接抵靠在具有肩部的圆柱形构件的圆柱形构件中，所述圆柱形构件具有至少具有中心孔的至少大小的玻璃料和圆柱形壁的直径的尺寸，所述玻璃料和圆柱形壁被紧固以抵抗在柱的轴线方向上的力 其入口到其出口。 垫圈将柱形保持器密封在柱壁上。 玻璃料由低于950℃的金 - 镍共晶温度但高于720℃的相不混溶温度在一起烧结在一起的镀金镍球形成。 选择玻璃料的尺寸和形状以通过使来自塔的流动路径均匀来减少拖尾。

公开(公告)号：US4882063A

公开(公告)日：1989-11-21

申请号：US73079

申请日：1987-07-13

申请人： Robert W. Allington ,  John N. Jones

发明人： Robert W. Allington ,  John N. Jones

IPC分类号： G01N30/34

CPC分类号： G01N30/34

摘要： To prevent the solvents forming a gradient from mixing at the wrong place and to provide for accurate composition at start of the gradient in spite of solvent pressure variations, a microliquid or supercritical fluid chromatograph includes a combined mixer and pressure detector in which equal pressures of the two solvents in the gradient are detected by displacement of a ferromagnetic poppet in the mixing chamber. The poppet serves as a stop for the final solvent until the pressures are substantially equal and then its movement is detected by a circuit related to a linear variable differential transformer. The signal energizes a circuit which drives one of the sensing coils to drive the poppet during the gradient to provide mixing.