公开(公告)号：US4911837A

公开(公告)日：1990-03-27

申请号：US339473

申请日：1989-04-17

申请人： Robert W. Allington ,  Yoossef Tehrani ,  John N. Jones

发明人： Robert W. Allington ,  Yoossef Tehrani ,  John N. Jones

IPC分类号： B01D15/08 ,  B01D15/22 ,  G01N30/60 ,  G01N30/74

CPC分类号： B01D15/22 ,  G01N30/603 ,  G01N30/6017 ,  G01N30/6026 ,  G01N30/6052 ,  G01N30/74

摘要： To reduce tailing, the frit at the outlet to the liquid chromatographic column has a diameter substantially equal to that of the inside diameter of the outlet end of the column and less than two millimeters. It is held directly against the packing of the column within a cylindrical member having a shoulder with a central aperture at least the size of the diameter of the frit and cylindrical walls which are fastened to resist force in the direction of the axis of the column from its inlet to its outlet. A gasket seals the cylindrical holder against the column wall. The frit is formed of gold-plated nickel spheres sintered together at a temperature lower than the gold-nickel eutectic temperature of 950 degrees Celsius but above the phase-immiscibility temperature of 720 degrees Celsius. The size and shape of the frit is selected to reduce tailing by causing the flow path from the column to be uniform.

摘要翻译： 为了减少拖尾，液相色谱柱出口处的玻璃料的直径基本上等于柱的出口端的内径，直径小于2毫米。 它被直接抵靠在具有肩部的圆柱形构件的圆柱形构件中，所述圆柱形构件具有至少具有中心孔的至少大小的玻璃料和圆柱形壁的直径的尺寸，所述玻璃料和圆柱形壁被紧固以抵抗在柱的轴线方向上的力 其入口到其出口。 垫圈将柱形保持器密封在柱壁上。 玻璃料由在950℃以下的金 - 镍共晶温度下高于720℃的相互不混溶温度的温度下烧结在一起的镀金镍球形成。 选择玻璃料的尺寸和形状以通过使来自塔的流动路径均匀来减少拖尾。

公开(公告)号：US06294088B1

公开(公告)日：2001-09-25

申请号：US09713895

申请日：2000-11-16

申请人： Robert W. Allington ,  Henry LeRoy Walters ,  Daniel Gene Jameson ,  Yoossef Tehrani

发明人： Robert W. Allington ,  Henry LeRoy Walters ,  Daniel Gene Jameson ,  Yoossef Tehrani

IPC分类号： B01D1508

CPC分类号： B01D11/0407 ,  B01D11/0203 ,  F04B9/042 ,  F04B15/08 ,  F04B49/065 ,  F04B2205/03 ,  F04B2205/05 ,  F04B2205/09 ,  F05B2230/41 ,  F05C2201/0493 ,  F05C2253/12 ,  F16K15/183 ,  G01F1/34 ,  G01N1/34 ,  G01N1/40 ,  G01N30/02 ,  G01N30/28 ,  G01N30/32 ,  G01N30/60 ,  G01N30/82 ,  G01N2001/4033 ,  G01N2001/4061 ,  G01N2030/6008 ,  G01N2030/6013 ,  G01N2035/0441 ,  G21F5/015 ,  B01D15/40

摘要： A variable-orifice fluid restrictor for use with a supercritical extractor or chromatograph includes an inlet line for fluid at a pressure above its critical pressure, an extended tubular probe having an inner and an outer surface and a proximal and a distal end. The proximal end of the probe is disposed toward the inlet line. The distal end of the probe includes an adjustable orifice means adapted for metering the fluid and having first and second orifice members and an adjusting stem having first and second ends. The adjustable orifice means is adjacent to the outer surface of the probe and the orifice means is adjustable with the adjusting stem. The end of the adjusting stem is located at the distal end of the probe and is adapted for moving the first orifice member with respect to the second orifice member to control the adjustable orifice for varying the restriction of fluid passing through the adjustable orifice. The distal end of the probe is inside the collector and the adjusting stem extends outside of the collector.

摘要翻译： 用于超临界萃取器或色谱仪的可变孔口流体限制器包括用于在高于其临界压力的压力下的流体的入口管线，具有内外表面和近端和远端的延伸管状探针。 探针的近端朝向入口线设置。 探针的远端包括适于计量流体并具有第一和第二孔口构件的调节孔口装置和具有第一和第二端部的调节杆。 可调整的孔口装置与探针的外表面相邻，孔口装置可用调节杆调节。 调节杆的端部位于探针的远端，并且适于相对于第二孔构件移动第一孔构件以控制可调节孔，以改变通过可调节孔的流体的限制。 探针的远端位于收集器内部，调节杆延伸到收集器外部。

公开(公告)号：US6149814A

公开(公告)日：2000-11-21

申请号：US74254

申请日：1998-05-07

申请人： Robert W. Allington ,  Henry LeRoy Walters ,  Daniel Gene Jameson ,  Yoossef Tehrani

发明人： Robert W. Allington ,  Henry LeRoy Walters ,  Daniel Gene Jameson ,  Yoossef Tehrani

IPC分类号： B01D11/02 ,  B01D11/04 ,  F04B9/04 ,  F04B15/08 ,  F04B49/06 ,  F16K15/18 ,  G01F1/34 ,  G01N1/34 ,  G01N1/40 ,  G01N30/02 ,  G01N30/28 ,  G01N30/32 ,  G01N30/60 ,  G01N30/82 ,  G01N35/04 ,  G21F5/015 ,  B01D11/00

CPC分类号： B01D11/0407 ,  B01D11/0203 ,  F04B15/08 ,  F04B49/065 ,  F04B9/042 ,  F16K15/183 ,  G01F1/34 ,  G01N1/34 ,  G01N1/40 ,  G01N30/28 ,  G01N30/82 ,  G21F5/015 ,  F04B2205/03 ,  F04B2205/05 ,  F04B2205/09 ,  F05B2230/41 ,  F05C2201/0493 ,  F05C2253/12 ,  G01N2001/4033 ,  G01N2001/4061 ,  G01N2030/6008 ,  G01N2030/6013 ,  G01N2035/0441 ,  G01N30/02 ,  G01N30/32 ,  G01N30/60

摘要： A variable-orifice fluid restrictor for use with a supercritical extractor or chromatograph includes an inlet line for fluid at a pressure above its critical pressure, an extended tubular probe having an inner and an outer surface and a proximal and a distal end. The proximal end of the probe is disposed toward the inlet line. The distal end of the probe includes an adjustable orifice means adapted for metering the fluid and having first and second orifice members and an adjusting stem having first and second ends. The adjustable orifice means is adjacent to the outer surface of the probe and the orifice means is adjustable with the adjusting stem. The end of the adjusting stem is located at the distal end of the probe and is adapted for moving the first orifice member with respect to the second orifice member to control the adjustable orifice for varying the restriction of fluid passing through the adjustable orifice.

摘要翻译： 用于超临界萃取器或色谱仪的可变孔口流体限制器包括用于高于其临界压力的压力的流体的入口管线，具有内外表面和近端和远端的延伸管状探针。 探针的近端朝向入口线设置。 探针的远端包括适于计量流体并具有第一和第二孔口构件的调节孔口装置和具有第一和第二端部的调节杆。 可调整的孔口装置与探针的外表面相邻，孔口装置可用调节杆调节。 调节杆的端部位于探针的远端，并且适于相对于第二孔构件移动第一孔构件以控制可调节孔，以改变通过可调节孔的流体的限制。

公开(公告)号：US5750027A

公开(公告)日：1998-05-12

申请号：US804682

申请日：1997-02-25

申请人： Robert W. Allington ,  Henry LeRoy Walters ,  Daniel Gene Jameson ,  Yoossef Tehrani

发明人： Robert W. Allington ,  Henry LeRoy Walters ,  Daniel Gene Jameson ,  Yoossef Tehrani

IPC分类号： B01D11/02 ,  B01D11/04 ,  F04B9/04 ,  F04B15/08 ,  F04B49/06 ,  F16K15/18 ,  G01F1/34 ,  G01N1/34 ,  G01N1/40 ,  G01N30/02 ,  G01N30/28 ,  G01N30/32 ,  G01N30/60 ,  G01N30/82 ,  G01N35/04 ,  G21F5/015

CPC分类号： B01D11/0407 ,  B01D11/0203 ,  F04B15/08 ,  F04B49/065 ,  F04B9/042 ,  F16K15/183 ,  G01F1/34 ,  G01N1/34 ,  G01N1/40 ,  G01N30/28 ,  G01N30/82 ,  G21F5/015 ,  F04B2205/03 ,  F04B2205/05 ,  F04B2205/09 ,  F05B2230/41 ,  F05C2201/0493 ,  F05C2253/12 ,  G01N2001/4033 ,  G01N2001/4061 ,  G01N2030/6008 ,  G01N2030/6013 ,  G01N2035/0441 ,  G01N30/02 ,  G01N30/32 ,  G01N30/60

摘要： A variable-orifice fluid restrictor for use with a supercritical extractor or chromatograph includes an inlet line for fluid at a pressure above its critical pressure, an extended tubular probe having an inner and an outer surface and a proximal and a distal end. The proximal end of the probe is disposed toward the inlet line. The distal end of the probe includes an adjustable orifice means adapted for metering the fluid and having first and second orifice members and an adjusting stem having first and second ends. The adjustable orifice means is adjacent to the outer surface of the probe and the orifice means is adjustable with the adjusting stem. The end of the adjusting stem is located at the distal end of the probe and is adapted for moving the first orifice member with respect to the second orifice member to control the adjustable orifice for varying the restriction of fluid passing through the adjustable orifice.

公开(公告)号：US5635070A

公开(公告)日：1997-06-03

申请号：US208121

申请日：1994-03-08

申请人： Robert W. Allington ,  Daniel G. Jameson ,  Dale A. Davison ,  Dale Clay ,  Robin R. Winter ,  Yoossef Tehrani

发明人： Robert W. Allington ,  Daniel G. Jameson ,  Dale A. Davison ,  Dale Clay ,  Robin R. Winter ,  Yoossef Tehrani

IPC分类号： B01D11/00 ,  B01D11/02 ,  B01D11/04 ,  F04B9/04 ,  F04B15/08 ,  F04B49/06 ,  F04B53/08 ,  F04B53/14 ,  F16K15/18 ,  G01F1/34 ,  G01N1/34 ,  G01N1/40 ,  G01N30/02 ,  G01N30/28 ,  G01N30/60 ,  G01N35/04 ,  G21F5/015

CPC分类号： G01N1/34 ,  B01D11/0203 ,  B01D11/0407 ,  F04B15/08 ,  F04B49/065 ,  F04B53/08 ,  F04B53/143 ,  F04B9/042 ,  F16K15/183 ,  G01F1/34 ,  G01N1/40 ,  G01N30/28 ,  G21F5/015 ,  F04B2201/0209 ,  F04B2205/03 ,  F04B2205/05 ,  F04B2205/09 ,  F05B2230/41 ,  F05C2201/0493 ,  F05C2253/12 ,  G01N2001/4033 ,  G01N2001/4061 ,  G01N2030/6013 ,  G01N2035/0441 ,  G01N30/02

摘要： To pump supercritical carbon dioxide into a supercritical extractor without overpressure in the reservoir and to record the volume being delivered, the pumping speed is controlled and the volume pumped is determined from a pressure-related signal used in a feedback circuit. The feedback controls the velocity of pumping in conjunction with programmed values to avoid destructive reverse torque. A cam in the pump controls piston stroke, has a depressurization portion with an initial slope equal to but in the opposite direction of the final slope, rounded transition slopes, increasing linear velocity to the refill portion and constant velocity in the refill portion.

公开(公告)号：US5614089A

公开(公告)日：1997-03-25

申请号：US542683

申请日：1995-10-13

申请人： Robert W. Allington ,  Henry L. Walters ,  Daniel G. Jameson ,  Yoossef Tehrani

发明人： Robert W. Allington ,  Henry L. Walters ,  Daniel G. Jameson ,  Yoossef Tehrani

IPC分类号： B01D11/02 ,  B01D11/04 ,  F04B9/04 ,  F04B15/08 ,  F04B49/06 ,  F16K15/18 ,  G01F1/34 ,  G01N1/34 ,  G01N1/40 ,  G01N30/02 ,  G01N30/28 ,  G01N30/32 ,  G01N30/60 ,  G01N30/82 ,  G01N35/04 ,  G21F5/015 ,  B01D15/08

CPC分类号： B01D11/0407 ,  B01D11/0203 ,  F04B15/08 ,  F04B49/065 ,  F04B9/042 ,  F16K15/183 ,  G01F1/34 ,  G01N1/34 ,  G01N1/40 ,  G01N30/28 ,  G01N30/82 ,  G21F5/015 ,  F04B2205/03 ,  F04B2205/05 ,  F04B2205/09 ,  F05B2230/41 ,  F05C2201/0493 ,  F05C2253/12 ,  G01N2001/4033 ,  G01N2001/4061 ,  G01N2030/6008 ,  G01N2030/6013 ,  G01N2035/0441 ,  G01N30/02 ,  G01N30/32 ,  G01N30/60

摘要： A variable-orifice fluid restrictor for use with a supercritical extractor or chromatograph includes an inlet line for fluid at a pressure above its critical pressure, an extended tubular probe having an inner and an outer surface and a proximal and a distal end. The proximal end of the probe is disposed toward the inlet line. The distal end of the probe includes an adjustable orifice means adapted for metering the fluid and having first and second orifice members and an adjusting stem having first and second ends. The adjustable orifice means is adjacent to the outer surface of the probe and the orifice means is adjustable with the adjusting stem. The end of the adjusting stem is located at the distal end of the probe and is adapted for moving the first orifice member with respect to the second orifice member to control the adjustable orifice for varying the restriction of fluid passing through the adjustable orifice.

摘要翻译： 用于超临界萃取器或色谱仪的可变孔口流体限制器包括用于高于其临界压力的压力的流体的入口管线，具有内外表面和近端和远端的延伸管状探针。 探针的近端朝向入口线设置。 探针的远端包括适于计量流体并具有第一和第二孔口构件的调节孔口装置和具有第一和第二端部的调节杆。 可调整的孔口装置与探针的外表面相邻，孔口装置可用调节杆调节。 调节杆的端部位于探针的远端，并且适于相对于第二孔构件移动第一孔构件以控制可调节孔，以改变通过可调节孔的流体的限制。

公开(公告)号：US06319410B1

公开(公告)日：2001-11-20

申请号：US09521630

申请日：2000-03-08

申请人： Robert William Allington ,  Daniel Gene Jameson ,  Dale A. Davison ,  Dale Clay ,  Robin R. Winter ,  Yoossef Tehrani

发明人： Robert William Allington ,  Daniel Gene Jameson ,  Dale A. Davison ,  Dale Clay ,  Robin R. Winter ,  Yoossef Tehrani

IPC分类号： B01D1100

CPC分类号： G01N1/34 ,  B01D11/0203 ,  B01D11/0407 ,  F04B9/042 ,  F04B15/08 ,  F04B49/065 ,  F04B53/08 ,  F04B53/143 ,  F04B2201/0209 ,  F04B2205/03 ,  F04B2205/05 ,  F04B2205/09 ,  F05B2230/41 ,  F05C2201/0493 ,  F05C2253/12 ,  F16K15/183 ,  G01F1/34 ,  G01N1/40 ,  G01N30/02 ,  G01N30/28 ,  G01N2001/4033 ,  G01N2001/4061 ,  G01N2030/6013 ,  G01N2035/0441 ,  G21F5/015 ,  B01D15/40

摘要： To provide performance particularly in handling supercritical extraction systems, a specially designed pump includes a cam-driven, single-plunger with a cam having a profile that enables the pumping system to avoid destructive reverse torque on the cam, gear train and drive motor after the cam passes top dead center. The plunger includes a seal having one side in contact with the supercritical fluid and a mechanism for supporting and aligning the piston on the other side of the seal to maintain the piston in alignment. The piston drive has Hertzian contact with the piston. The fluid volume leaving the pump is determined by measuring only pressure or other parameters related to flow and movement of the plunger. Measurement of the fluid volume leaving the pump is useful for recording or indicating the flow rate while the pump is operating.

摘要翻译： 为了提供特别在处理超临界萃取系统中的性能，专门设计的泵包括凸轮驱动的单柱塞，其具有凸轮，该凸轮具有轮廓，使得泵系统能够避免在凸轮，齿轮系和驱动马达之后的破坏性反向扭矩 凸轮通过上死点。 柱塞包括具有与超临界流体接触的一侧的密封件和用于在密封件的另一侧支撑和对准活塞以使活塞保持对准的机构。 活塞驱动器与活塞接触Hertzian。 通过仅测量与柱塞的流动和运动相关的压力或其它参数来确定离开泵的流体体积。 离开泵的流体体积的测量对于在泵运行时记录或指示流量是有用的。

公开(公告)号：US5755559A

公开(公告)日：1998-05-26

申请号：US673177

申请日：1996-06-26

申请人： Robert William Allington ,  Daniel Gene Jameson ,  Dale A. Davison ,  Dale Clay ,  Robin R. Winter ,  Yoossef Tehrani

发明人： Robert William Allington ,  Daniel Gene Jameson ,  Dale A. Davison ,  Dale Clay ,  Robin R. Winter ,  Yoossef Tehrani

IPC分类号： B01D11/00 ,  B01D11/02 ,  B01D11/04 ,  F04B9/04 ,  F04B15/08 ,  F04B49/06 ,  F04B53/08 ,  F04B53/14 ,  F16K15/18 ,  G01F1/34 ,  G01N1/34 ,  G01N1/40 ,  G01N30/02 ,  G01N30/28 ,  G01N30/60 ,  G01N35/04 ,  G21F5/015 ,  F04B49/00

CPC分类号： G01N1/34 ,  B01D11/0203 ,  B01D11/0407 ,  F04B15/08 ,  F04B49/065 ,  F04B53/08 ,  F04B53/143 ,  F04B9/042 ,  F16K15/183 ,  G01F1/34 ,  G01N1/40 ,  G01N30/28 ,  G21F5/015 ,  F04B2201/0209 ,  F04B2205/03 ,  F04B2205/05 ,  F04B2205/09 ,  F05B2230/41 ,  F05C2201/0493 ,  F05C2253/12 ,  G01N2001/4033 ,  G01N2001/4061 ,  G01N2030/6013 ,  G01N2035/0441 ,  G01N30/02

摘要： In a piston pump for pumping liquid carbon dioxide at a temperature below 30 degrees Fahrenheit and pressures at least as high as 7500 psi, the volume leaving the pump is determined by measuring only pressure or other parameter related to flow and movement of the plunger. The position of the piston is measured and the resulting displacement is integrated to determine volume of fluid pumped.

摘要翻译： 在用于在低于30华氏度的温度下泵送液体二氧化碳和至少高达7500psi的压力的活塞泵中，通过仅测量与柱塞的流动和运动相关的压力或其它参数来确定离开泵的体积。 测量活塞的位置，并将所得到的位移整合在一起，以确定泵送的流体体积。

公开(公告)号：US6086767A

公开(公告)日：2000-07-11

申请号：US879395

申请日：1997-06-20

申请人： Henry LeRoy Walters ,  Robert William Allington ,  Daniel Gene Jameson ,  Yoossef Tehrani

发明人： Henry LeRoy Walters ,  Robert William Allington ,  Daniel Gene Jameson ,  Yoossef Tehrani

IPC分类号： B01D11/02 ,  B01D11/04 ,  F04B9/04 ,  F04B15/08 ,  F04B49/06 ,  F16K15/18 ,  G01F1/34 ,  G01N1/34 ,  G01N1/40 ,  G01N30/02 ,  G01N30/28 ,  G01N30/32 ,  G01N30/60 ,  G01N30/82 ,  G01N35/04 ,  G21F5/015 ,  B01D15/08

CPC分类号： B01D11/0203 ,  B01D11/0407 ,  F04B15/08 ,  F04B49/065 ,  F04B9/042 ,  F16K15/183 ,  G01F1/34 ,  G01N1/34 ,  G01N1/40 ,  G01N30/28 ,  G01N30/82 ,  G21F5/015 ,  F04B2205/03 ,  F04B2205/05 ,  F04B2205/09 ,  F05B2230/41 ,  F05C2201/0493 ,  F05C2253/12 ,  G01N2001/4033 ,  G01N2001/4061 ,  G01N2030/6008 ,  G01N2030/6013 ,  G01N2035/0441 ,  G01N30/02 ,  G01N30/32 ,  G01N30/60

摘要： An automatic variable-orifice fluid restrictor for use with a supercritical extractor having a collection trap or a supercritical chromatograph includes an inlet line for fluid at a pressure above its critical pressure, an extended tubular probe having an inner and an outer surface and a proximal and a distal end. The proximal end of the probe carries an inlet connected to the inlet line and is outside of the trap. The distal end of the probe includes a variable orifice means adapted for metering the fluid. The variable orifice means is adjacent to the outer surface of the probe and is located in the midst of the trap. The variable orifice means is adjusted by an adjusting stem having first and second ends. The first end of the adjusting stem is connected to automatic control means such as a servo at the proximal end of the probe and outside of the trap. The second end of the adjusting stem varies the area of the orifice by moving a first orifice member. The stationary second orifice member cooperates with the first orifice member to form the orifice. The first orifice member moves axially when the orifice is closed and moves both axially and rotationally when the orifice is open or partially open. This cleans deposits from the orifice without damaging the orifice parts by high pressure notional physical contact.

摘要翻译： 用于具有收集阱或超临界色谱仪的超临界萃取器的自动可变孔流体限制器包括用于高于其临界压力的压力的流体的入口管线，具有内表面和外表面的延伸管状探针， 一个远端 探针的近端带有连接到入口管线并且位于捕集器外部的入口。 探针的远端包括适于计量流体的可变孔口装置。 可变孔口装置邻近探针的外表面并且位于捕获器的中间。 可变孔装置由具有第一和第二端的调节杆调节。 调节杆的第一端连接到自动控制装置，例如在探头的近端处的伺服机构和陷阱的外部。 调节杆的第二端通过移动第一孔口部件来改变孔口的面积。 固定的第二孔口构件与第一孔口构件协作以形成孔口。 当孔口关闭时，第一孔口部件轴向移动，当孔口打开或部分打开时，第一孔口部件轴向和旋转地移动。 这样可以从孔中清除沉积物，而不会通过高压物理接触而损坏孔口部件。

公开(公告)号：US5173163A

公开(公告)日：1992-12-22

申请号：US463357

申请日：1990-01-11

申请人： Yoossef Tehrani

发明人： Yoossef Tehrani

IPC分类号： G02F1/167 ,  G01N27/447 ,  G09F9/37

CPC分类号： G01N27/44756 ,  G01N27/44743

摘要： To inject sample into an electrophoresis capillary tube having a separating medium, the end of the capillary tube is inserted in an injection block with a liquid tight seal and a syringe is inserted into the block to apply fluid to the end of the capillary tube. The injection block provides split flow injection. A high voltage isolated switching arrangement switches the end of the capillary from the injection block to buffer at a high electrical potential to accomplish the electrophoretic separation. A second injection block is used to purge the capillary tube and can be used to supply separating medium as needed.