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13 条记录 (耗时 0.034 秒)

    Polymeric surface coatings
    2.
    发明授权
    Polymeric surface coatings 失效
    聚合物表面涂层

    公开(公告)号：US5705583A

    公开(公告)日：1998-01-06

    申请号：US475620

    申请日：1995-06-07

    申请人： Roderick W. J. Bowers ,  Stephen A. Jones ,  Peter W. Stratford ,  Stephen A. Charles

    发明人： Roderick W. J. Bowers ,  Stephen A. Jones ,  Peter W. Stratford ,  Stephen A. Charles

    IPC分类号： C08F246/00 ,  C08F230/02 ,  B05D1/18 ,  B05D5/00 ,  C08F226/02

    CPC分类号： C08F246/00 ,  C07F9/091 ,  C07F9/65742

    摘要： Polymers of one or more radical polymerisable monomers which polymer has pendant groups bearing a center of permanent positive charge and other pendant groups capable of stably binding the polymer to a surface are useful in the treatment of surfaces to render them biocompatible. The polymers may contain pendant groups which bind the polymer to a surface by physisorption, covalent bonding or ionic interactions. Additionally reactive groups in the polymer may serve as points for attachment of ligands to the polymer when coated on a surface.

    摘要翻译： 聚合物具有带有永久正电荷中心的侧基的聚合物和能够将聚合物稳定地结合到表面的其它侧基的一种或多种可自由基聚合单体的聚合物可用于处理表面以使其具有生物相容性。 聚合物可以含有通过物理吸附，共价键或离子相互作用将聚合物结合到表面的侧基。 聚合物中另外的反应性基团可以用作在涂覆在表面上时将配体连接到聚合物上的点。

    Method of performing assay for analyte in liquid medium
    7.
    发明授权
    Method of performing assay for analyte in liquid medium 失效
    在液体介质中进行分析物测定的方法

    公开(公告)号：US4745077A

    公开(公告)日：1988-05-17

    申请号：US692162

    申请日：1985-01-17

    申请人： John Holian ,  John C. Edwards ,  John K. Martin ,  Stephen A. Charles

    发明人： John Holian ,  John C. Edwards ,  John K. Martin ,  Stephen A. Charles

    IPC分类号： A61K39/00 ,  G01N33/543 ,  G01N33/553 ,  G01N33/533

    CPC分类号： G01N33/54333 ,  Y10S436/80 ,  Y10S436/809

    摘要： The invention concerns assays, such a immunoassays or two-site immunometric assays, performed using a labelled reagent and another reagent bound to magnetically attractable particles which are suspendable but insoluble in a liquid assay medium. After the labelled reagent has become partitioned between the liquid phase and the particles, in proportions which depend on the concentration of an analyte in a sample, the liquid phase is removed. Then the particles are re-suspended in another liquid medium, and the concentration of label observed. The method is particularly suitable for fluorescent and chemiluminescent' label systems, and can conveniently be performed in microtiter plates in which the wells are optically screened from one another, the observations being made from above or below the wells.

    摘要翻译： 本发明涉及使用标记的试剂和结合到可悬浮但不溶于液体测定培养基的磁性可吸引颗粒的另一试剂进行的测定，如免疫测定或双位点免疫测定。 在标记试剂在液相和颗粒之间分配后，以取决于样品中分析物浓度的比例，液相被除去。 然后将颗粒重新悬浮在另一种液体介质中，并观察标签的浓度。 该方法特别适用于荧光和化学发光的标记系统，并且可以方便地在微孔板中进行，其中孔彼此光学屏蔽，观察是从孔的上方或下方进行的。