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    Process for producing L-tryptophan
    2.
    发明授权
    Process for producing L-tryptophan 失效
    生产L-色氨酸的方法

    公开(公告)号：US5447857A

    公开(公告)日：1995-09-05

    申请号：US147541

    申请日：1993-11-05

    申请人： Ryoichi Katsumata ,  Masato Ikeda ,  Keiko Nakanishi

    发明人： Ryoichi Katsumata ,  Masato Ikeda ,  Keiko Nakanishi

    IPC分类号： C12N1/20 ,  C12N1/21 ,  C12N15/00 ,  C12N15/09 ,  C12N15/52 ,  C12P13/22 ,  C12R1/13 ,  C12R1/15 ,  C12N15/77

    CPC分类号： C12P13/227 ,  C12N15/52

    摘要： L-tryptophan is produced by constructing a recombinant DNA composed of a vector DNA and DNA fragments bearing all of genetic information relating to the synthesis of DS, AS, PRT, PRAI, InGPS, TS and PGDH, introducing the recombinant DNA into a microorganism belonging to the genus Corynebacterium or Brevibacterium, culturing the microorganism in a medium, and recovering L-tryptophan accumulated in the culture.

    摘要翻译： 通过构建由载体DNA构成的重组DNA和具有与DS，AS，PRT，PRAI，InGPS，TS和PGDH的合成有关的所有遗传信息的DNA片段，将重组DNA引入到属于微生物的微生物中来产生L-色氨酸 到棒状杆菌属或短杆菌属，在培养基中培养微生物，并回收在培养物中积累的L-色氨酸。

    Process for producing amino acids
    5.
    发明授权
    Process for producing amino acids 失效
    生产氨基酸的方法

    公开(公告)号：US5498532A

    公开(公告)日：1996-03-12

    申请号：US633169

    申请日：1990-12-28

    申请人： Ryoichi Katsumata ,  Yasuhiro Kikuchi ,  Keiko Nakanishi

    发明人： Ryoichi Katsumata ,  Yasuhiro Kikuchi ,  Keiko Nakanishi

    IPC分类号： C12P7/04 ,  C12N1/20 ,  C12N1/21 ,  C12N15/00 ,  C12N15/09 ,  C12N15/52 ,  C12N15/74 ,  C12P13/04 ,  C12R1/13 ,  C12R1/15 ,  C12R1/19 ,  C12N15/77

    CPC分类号： C12N15/74 ,  C12N15/52 ,  C12P13/04 ,  C12R1/13 ,  C12R1/15 ,  Y10S435/849

    摘要： The invention relates to coryneform microorganisms capable of assimilating lactose which carry a recombinant DNA capable of conferring the ability to assimilate lactose on coryneform microorganisms; and to a process for producing L-amino acids which comprises culturing said coryneform microorganism capable of assimilating lactose in a culture medium containing lactose to form an amino acid, and recovering said amino acid accumulated in the culture broth. Further, the invention relates to a method for preparing recombinant plasmids containing a DNA fragment essential to the expression of a gene in coryneform microorganisms.

    摘要翻译： 本发明涉及能够同化乳糖的棒状细菌，其携带能够赋予棒状微生物乳糖的能力的重组DNA; 以及生产L-氨基酸的方法，其包括在含有乳糖的培养基中培养能够吸收乳糖的所述棒状细菌，以形成氨基酸，并回收在培养液中积累的所述氨基酸。 此外，本发明涉及一种制备含有在棒状细菌中表达基因所必需的DNA片段的重组质粒的方法。

    Process for producing L-tryptophan, L-tyrosine or L-phenylalanine
    6.
    发明授权
    Process for producing L-tryptophan, L-tyrosine or L-phenylalanine 失效
    生产L-色氨酸，L-酪氨酸或L-苯丙氨酸的方法

    公开(公告)号：US5605818A

    公开(公告)日：1997-02-25

    申请号：US424621

    申请日：1995-04-19

    申请人： Ryoichi Katsumata ,  Masato Ikeda

    发明人： Ryoichi Katsumata ,  Masato Ikeda

    IPC分类号： C12N1/21 ,  C12N9/10 ,  C12N15/09 ,  C12N15/54 ,  C12P13/22 ,  C12R1/13 ,  C12R1/15

    CPC分类号： C12P13/22 ,  C12N9/1022

    摘要： Disclosed is a process for producing an aromatic amino acid selected from the group consisting of L-tryptophan, L-tyrosine and L-phenylalanine which comprises culturing in a medium a mutant strain of the genus Corynebacterium or Brevibacterium, being capable of producing the aromatic amino acid and also having higher transketolase activity than that of a parent strain thereof until the aromatic amino acid is produced and accumulated in the culture, and recovering the aromatic amino acid therefrom.

    摘要翻译： 公开了一种生产选自L-色氨酸，L-酪氨酸和L-苯丙氨酸的芳族氨基酸的方法，其包括在培养基中培养棒状杆菌属或短杆菌属的突变株，能够产生芳族氨基 酸，并且具有比其亲本菌株高的转酮醇酶活性，直到在培养物中产生和积累芳香族氨基酸，并从其中回收芳族氨基酸。

    Process for producing L-tryptophan
    7.
    发明授权
    Process for producing L-tryptophan 失效
    生产L-色氨酸的方法

    公开(公告)号：US5563052A

    公开(公告)日：1996-10-08

    申请号：US245823

    申请日：1994-05-18

    申请人： Ryoichi Katsumata ,  Masato Ikeda

    发明人： Ryoichi Katsumata ,  Masato Ikeda

    IPC分类号： C12N1/20 ,  C12N1/21 ,  C12N15/00 ,  C12N15/09 ,  C12N15/52 ,  C12P13/22 ,  C12R1/13 ,  C12R1/15 ,  C12P13/72 ,  C12N15/63 ,  C12N15/77

    CPC分类号： C12N15/52 ,  C12P13/227

    摘要： L-tryptophan is produced by constructing a recombinant DNA composed of a vector DNA and DNA fragments bearing all of genetic information relating to the synthesis of DS, AS, PRT, PRAI, InGPS and TS, introducing the recombinant DNA in a microorganism belonging to the genus Corynebacterium or Brevibacterium, culturing the microorganism in a medium, and recovering L-tryptophan accumulated in the culture.

    摘要翻译： 通过构建由载体DNA构成的重组DNA和具有与DS，AS，PRT，PRAI，InGPS和TS的合成有关的所有遗传信息的DNA片段，产生L-色氨酸，将重组DNA引入属于 棒状杆菌属或短杆菌属，在培养基中培养微生物，并回收在培养物中积累的L-色氨酸。

    Process for producing alanine
    9.
    发明授权
    Process for producing alanine 失效
    丙氨酸生产方法

    公开(公告)号：US5559016A

    公开(公告)日：1996-09-24

    申请号：US170936

    申请日：1993-12-21

    申请人： Ryoichi Katsumata ,  Shin'ichi Hashimoto

    发明人： Ryoichi Katsumata ,  Shin'ichi Hashimoto

    IPC分类号： C12N1/21 ,  C12N9/06 ,  C12N15/09 ,  C12N15/53 ,  C12P13/06 ,  C12R1/06 ,  C12R1/13 ,  C12R1/15 ,  C12N9/02

    CPC分类号： C12N9/0016 ,  C12P13/06

    摘要： A process for producing alanine which comprises culturing in a medium a microorganism belonging to the genus Escherichia, Corynebacterium or Brevibacterium which has an L-alanine dehydrogenase activity and is capable of producing alanine, allowing the microorganism to produce and accumulate alanine in the culture medium, and recovering alanine from the culture medium.

    摘要翻译： 一种制备丙氨酸的方法，其包括在培养基中培养属于具有L-丙氨酸脱氢酶活性并具有L-丙氨酸脱氢酶活性并具有L-丙氨酸脱氢酶活性的埃希氏杆菌属，棒状杆菌属或短杆菌属的微生物，使微生物在培养基中产生和积累丙氨酸， 并从培养基中回收丙氨酸。