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公开(公告)号：US20240344990A1
公开(公告)日：2024-10-17
申请号：US18294858
申请日：2022-06-30
Applicant: SHIMADZU CORPORATION
Inventor： Tomoki SASAYAMA
CPC classification number: G01N21/65 , G01J3/0208 , G01J3/021 , G01J3/0229 , G01J3/18 , G01J3/4412 , G02B21/16
Abstract: A microscopic Raman spectroscopy device includes laser oscillators (excitation light sources) that emit excitation laser lights (excitation lights) of different wavelengths, a spectrometer that uses a diffraction grating to disperse Raman scattering light emitted from a sample by irradiation with the excitation laser light from the laser oscillator, and a CCD detector that detects and photoelectrically converts the Raman scattering light dispersed by the spectrometer. The spectrometer includes incident apertures, a plurality of (two) optical systems that guide the Raman scattering light incident from the incident aperture to the diffraction grating, and a plurality of light beams dispersed by the diffraction grating are incident on one imaging lens in tandem.
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公开(公告)号：US20240175751A1
公开(公告)日：2024-05-30
申请号：US18520342
申请日：2023-11-27
Applicant: SHIMADZU CORPORATION
Inventor： Tomoyo TAO , Tomoki SASAYAMA , Ryuta SHIBUTANI , Atsuhiko OTAGURO , Fumiya KATSUTANI
CPC classification number: G01J3/44 , G01J3/0202 , G01J3/0208 , G01J3/021 , G01J3/108
Abstract: An infrared Raman device is capable of switching and performing Raman measurement and first infrared measurement on a sample. The infrared Raman device includes an objective lens for Raman measurement; a first observation lens for infrared measurement; a laser light source that generates laser light; a first infrared light source that generates first infrared light; and a mirror. The mirror is disposed at time of the Raman measurement to reflect the laser light to cause the laser light to pass through the objective lens for Raman measurement and reflect Raman light generated from the sample by the laser light that passes through the objective lens for Raman measurement and radiated to the sample. The Raman light passes back through the objective lens for Raman measurement.
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公开(公告)号：US20170299515A1
公开(公告)日：2017-10-19
申请号：US15098598
申请日：2016-04-14
Applicant: SHIMADZU CORPORATION
Inventor： Tomoki SASAYAMA
CPC classification number: G01N21/645 , G01N2021/6463 , G01N2201/022 , G01N2201/025 , G02B5/208 , G02B26/023
Abstract: An optical measuring device including a sample placement portion for a measurement sample to be placed therein; a light source portion for emitting a measurement beam toward the measurement sample that is placed in the sample placement portion; and a detector for detecting sample information from a measurement sample that is disposed in the sample placement portion; a cover portion that is able to open and close, for accessing the interior of the sample placement portion, is formed on the sample placement portion; an optical element member for not transmitting light of at least a prescribed wavelength band within the measurement beam; and a driving mechanism that is linked mechanically with the opening and closing of the cover portion to move the optical element member.
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公开(公告)号：US20240094130A1
公开(公告)日：2024-03-21
申请号：US18214507
申请日：2023-06-26
Applicant: SHIMADZU CORPORATION
Inventor： Fumiya KATSUTANI , Tomoki SASAYAMA , Tomoyo TAO , Atsuhiko OTAGURO , Ryuta SHIBUTANI , Hisato FUKUDA
CPC classification number: G01N21/65 , G01J3/0208 , G01J3/10 , G01J3/44 , G02B21/06 , G01J2003/102
Abstract: A Raman infrared compound microscope device includes: a first light source that generates laser light; a second light source that generates infrared light; a third light source that generates visible light; and a first optical system. The first optical system orients the visible light having reached the first optical system in different directions between when performing a Raman analysis using Raman light generated from a sample by irradiation of the laser light and when performing a first infrared analysis using the infrared light having passed through the sample.
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Patent Agency Ranking
5.发明公开公开(公告)号：US20230314219A1
公开(公告)日：2023-10-05
申请号：US18011019
申请日：2021-03-19
Applicant: SHIMADZU CORPORATION
Inventor： Tomoki SASAYAMA , Yugo ISHIHARA , Takeshi MAJI , Tomoyo TAO
CPC classification number: G01J3/4412 , G01J3/0216 , G01J3/0229 , G01J3/0237 , G01J3/021 , G01J3/0218 , G01N21/65 , G01J3/0297
Abstract: Microscopic Raman spectroscopy device that detects and analyzes Raman scattering light emitted from sample irradiated with excitation light includes: laser light source that emits excitation light; spectrometer for measuring spectrum of the Raman scattering light; wavelength discriminator such as a dichroic filter that reflects the excitation light emitted from the laser light source toward the sample and transmits Raman scattering light emitted from the sample toward the spectrometer; condenser lens arranged between wavelength discriminator and the spectrometer for condensing the Raman scattering light passing through the wavelength discriminator; aperture arranged between the condenser lens and the spectrometer for limiting Raman scattering light incident on the spectrometer; adjusting means for adjusting to match a position of spot image of Raman scattering light condensed by condensing lens with a position of the aperture so that light amount of Raman scattering light passing through the aperture is maximized.
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公开(公告)号：US20240255397A1
公开(公告)日：2024-08-01
申请号：US18564530
申请日：2022-03-09
Applicant: SHIMADZU CORPORATION
Inventor： Kuniaki KANAMARU , Tomoki SASAYAMA
IPC: G01N3/06
CPC classification number: G01N3/068 , G01N2203/0647
Abstract: In measuring stress or strain of a sample (1), a test sheet (90) adhered to the sample (1) is irradiated with excitation light. The test sheet (90) includes a substrate layer (92) containing a polymeric material and a stress luminescent layer (91) formed on the substrate layer (92). The stress luminescent layer (91) contains a stress luminescent material. A captured image of the test sheet (90) irradiated with the excitation light is acquired, and the luminous intensity for the test sheet is identified from the captured image.
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7.发明公开公开(公告)号：US20230390943A1
公开(公告)日：2023-12-07
申请号：US18033801
申请日：2021-09-07
Applicant: SHIMADZU CORPORATION
Inventor： Tomoki SASAYAMA , Nobuhiro HANAFUSA
CPC classification number: B25J15/0033 , G01N35/0099 , B67B7/16 , C12M1/34 , C12N15/09 , C12Q1/686
Abstract: An opening apparatus includes a temperature adjustment section that holds a container body of a PCR container, an opening/closing unit, a moving device, and a control device. The opening and closing unit includes: a rotating member that applies a force to a lid in a direction to open the lid as the rotating member rotates with a projection in contact with the lid in a closed state; and a motor that rotates the rotating member. The moving device moves the temperature adjustment section relative to the rotating member. In conjunction with driving and thus rotating the rotating member, the control device controls the moving device so that the PCR container moves horizontally in a direction from a hinge of the PCR container toward a flange of the PCR container.
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公开(公告)号：US20210372868A1
公开(公告)日：2021-12-02
申请号：US17322088
申请日：2021-05-17
Applicant: SHIMADZU CORPORATION
Inventor： Yusuke YOKOI , Momoyo YAMAKAWA , Naoya FUJIWARA , Kenta ADACHI , Hiroaki TSUSHIMA , Tomoki SASAYAMA
Abstract: Provided is a stress measurement device capable of easily grasping the behavior of a stress generation site in a sample. The stress measurement device is provided with a camera for imaging light emitted by a stress luminescent material, a controller for processing an image captured by the camera, and a display for displaying the image processed by the controller. The controller detects the stress generation site according to a luminescence distribution of the stress luminescent material for each of the plurality of time-series images captured by the camera and controls the display such that each stress generation site detected for each of the plurality of images is displayed on one image in a superimposed manner in mutually different display modes.
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公开(公告)号：US20140163388A1
公开(公告)日：2014-06-12
申请号：US14099126
申请日：2013-12-06
Inventor： Tomoki SASAYAMA , Satoshi YAMAMOTO , Kohei SOGA
IPC: A61B5/00
CPC classification number: A61B5/0071 , F04C2270/041 , G01N21/6456
Abstract: Measuring light emitted from a laser light source and split into four light rays through optical fibers is emitted into a space from emission units, and bent upward at a mirror. The measuring light passes through a window in the center of the sample stage and strikes a lower surface of the biological sample placed on the sample stage. A portion of fluorescence emitted through excitation by the measuring light passes through the window, is bent in an opposite direction from the measuring light by the mirror, and guided to a fluorescence camera. An objective lens, and a spectroscopic unit for separating visible wavelength components are horizontally arranged between the camera and the mirror. Although the projection of the measuring light and the detection of the fluorescence are performed perpendicularly to the biological sample, the optical components and elements are horizontally arranged.
Abstract translation: 测量从激光光源发射并通过光纤分解成四个光线的光从发射单元发射到空间中，并以镜子向上弯曲。 测量光通过样品台中心的窗口，并撞击放置在样品台上的生物样品的下表面。 通过测量光的激发发出的一部分荧光通过窗口，通过反射镜沿与测量光相反的方向弯曲，并被引导到荧光相机。 物镜和用于分离可见波长分量的分光单元水平地布置在相机和反射镜之间。 虽然测量光的投影和荧光的检测是垂直于生物样品进行的，但光学部件和元件水平排列。
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