Patent search ap:("SYMRISE AG") AND inv:"Hubert Loges" Page 1

1.

发明授权
Use of physiological cooling active ingredients, and agents containing such active ingredients 有权

公开(公告)号：US09718839B2

公开(公告)日：2017-08-01

申请号：US14533345

申请日：2014-11-05

Applicant: SYMRISE AG , BASF SE

Inventor： Thomas Subkowski , Michael Backes , Heiko Oertling , Arnold Machinek , Hubert Loges , Ulrike Simchen , Horst Surburg , Claus Bollschweiler , Jens Wittenberg , Wolfgang Siegel

IPC: C07D495/20 , A23L1/30 , A24B13/00 , A24D1/00 , A61K31/4375 , A61K31/438 , A61K31/506 , A61K31/5377 , A61K8/49 , A61Q11/00 , C07D401/04 , C07D491/147 , A23G3/36 , A23G4/06 , A23L2/52 , A61K31/165 , A61K31/167 , A61K31/36 , A61K31/426 , A61K31/4402 , A61K31/443 , A61K31/4741 , A61K31/4743 , A61K31/513 , A61Q19/00 , C07C233/11 , C07C235/36 , C07C235/38 , C07D213/75 , C07D317/60 , C07D405/12 , C07D495/22 , C09D5/16 , D06M15/03 , D06M15/07 , D06M16/00 , A23L27/20 , A23L33/10 , A61Q17/04

CPC classification number: C07D495/20 , A23G3/36 , A23G4/06 , A23L2/52 , A23L27/2054 , A23L33/10 , A23V2002/00 , A24B13/00 , A24D1/002 , A61K8/49 , A61K8/4953 , A61K31/165 , A61K31/167 , A61K31/36 , A61K31/426 , A61K31/4375 , A61K31/438 , A61K31/4402 , A61K31/443 , A61K31/4741 , A61K31/4743 , A61K31/506 , A61K31/513 , A61K31/5377 , A61K2800/10 , A61K2800/244 , A61K2800/78 , A61Q11/00 , A61Q17/04 , A61Q19/00 , A61Q19/004 , C07C233/11 , C07C235/36 , C07C235/38 , C07C2601/14 , C07D213/75 , C07D317/60 , C07D401/04 , C07D405/12 , C07D491/147 , C07D495/22 , C09D5/1625 , D06M15/03 , D06M15/07 , D06M16/00

Abstract: The invention relates to a TRPM8 modulator for achieving a cooling effect on the skin or a mucous membrane.

2.

发明授权
Use of physiological cooling active ingredients, and compositions comprising such active ingredients 有权

公开(公告)号：US11434220B2

公开(公告)日：2022-09-06

申请号：US16642954

申请日：2018-08-31

Applicant: BASF SE , SYMRISE AG

Inventor： Benoît Join , Jekaterina Ongouta , Michael Backes , Rahim Brodhage , Arnold Machinek , Hubert Loges , Susanne Mundt , Tom Somers , Thomas Subkowski , Jens Wittenberg , Martin Weisel , Wolfgang Siegel , Claus Bollschweiler , Ralf Pelzer

IPC: C07D317/46 , C07C323/41 , C07D405/12 , C07D213/75 , C07D231/40 , C07D407/12 , C07D307/14 , C07D409/12 , C07D409/14 , C07D405/14 , A61K8/49 , A61K8/46 , A61Q11/00 , A23L29/00 , A23L27/00 , A23G3/36

Abstract: The invention relates primarily to a method of modulation, preferably of in vitro and/or in vivo modulation, of the cold menthol receptor TRPM8, wherein the receptor is contacted with at least one modulator selected from the group consisting of the compounds of the structure type 1 described herein. The present invention further relates to corresponding uses and compositions comprising such compounds.

3.

发明授权
Preparations having a cooling effect 有权

公开(公告)号：US11234450B2

公开(公告)日：2022-02-01

申请号：US15804026

申请日：2017-11-06

Applicant: Symrise AG , Sven Siegel

Inventor： Torsten Kulke , Sven Siegel , Michael Backes , Benoit Join , Hubert Loges , Günter Kindel

IPC: A23G4/06 , A61K8/02 , A61K8/69 , A61K8/34 , A61K8/37 , A61K8/42 , A61K8/49 , A61K31/045 , A61K31/216 , A61K31/343 , A61K31/357 , A61K31/381 , A61K31/4155 , A61K31/42 , A61K31/426 , A61K31/4436 , A61K31/497 , A61Q5/00 , A23L27/20 , A23L29/00 , A61Q19/10 , A61Q11/00 , A61Q19/00 , A61Q17/04

Abstract: Proposed are preparations, comprising special amides and menthol or menthol compounds or aromatic substances, characterized in that they have improved flavor and scent properties, and also that they allow the production of preparations, particularly emulsions with improved shelf life.

4.

发明申请
MIXTURES HAVING IMPROVED COOLING EFFECT 有权
Title translation: 具有改善冷却效果的混合物

公开(公告)号：US20150139918A1

公开(公告)日：2015-05-21

申请号：US14401691

申请日：2013-04-18

Applicant: SYMRISE AG

Inventor： Rita Lages , Hubert Loges , Arnold Machinek , Gabriele Neuendorff , Erich Dilk , Heiko Oertling

IPC: A23L1/22 , A61K8/34 , A61K31/11 , A23G3/38 , A61Q11/00 , A23L1/226 , A23G4/06 , A23G3/36 , A61K8/33 , A61K31/045

CPC classification number: A23L27/204 , A23G3/36 , A23G3/38 , A23G4/06 , A23G9/32 , A23L27/86 , A23L27/88 , A23V2002/00 , A61K8/33 , A61K8/34 , A61K31/045 , A61K31/11 , A61K2800/244 , A61Q11/00 , A61Q19/00

Abstract: A mixtures which contain (a) at least one phenylalkenal of formula (I) wherein R1 and R2 independently represent hydrogen, a methyl or phenyl group, R3 represents hydrogen, a phenyl group, alkenyl group or a linear or branched alkyl group with 1 to 5 carbon atoms, and the broken double lines independently represent a single bond or a double bond, and (b) at least one physiological cooling agent.

Abstract translation: 含有（a）至少一种式（I）的苯基链烯烃的混合物，其中R 1和R 2独立地表示氢，甲基或苯基，R 3表示氢，苯基，烯基或直链或支链烷基， 5个碳原子，并且破碎的双线分别独立地表示单键或双键，和（b）至少一种生理冷却剂。

5.

发明授权
Use of physiological cooling active ingredients, and agents containing such active ingredients 有权

公开(公告)号：US10584134B2

公开(公告)日：2020-03-10

申请号：US15629015

申请日：2017-06-21

Applicant: SYMRISE AG , BASF SE

Inventor： Thomas Subkowski , Michael Backes , Heiko Oertling , Arnold Machinek , Hubert Loges , Ulrike Simchen , Horst Surburg , Claus Bollschweiler , Jens Wittenberg , Wolfgang Siegel

IPC: C07D495/20 , A23L27/20 , A23L33/10 , A24B13/00 , A24D1/00 , A61K31/4375 , A61K31/438 , A61K31/5377 , A61Q11/00 , C07C233/11 , C07C235/36 , C07C235/38 , C07D213/75 , C07D317/60 , C07D401/04 , C07D405/12 , C07D491/147 , C07D495/22 , C09D5/16 , D06M15/03 , D06M15/07 , D06M16/00 , A23G3/36 , A23G4/06 , A23L2/52 , A61K8/49 , A61K31/165 , A61K31/167 , A61K31/36 , A61K31/426 , A61K31/4402 , A61K31/443 , A61K31/4741 , A61K31/4743 , A61K31/506 , A61K31/513 , A61Q19/00 , A61Q17/04

Abstract: The invention relates to a TRPM8 modulator for achieving a cooling effect on the skin or a mucous membrane.

6.

发明授权
Mixtures having improved cooling effect 有权

公开(公告)号：US09743685B2

公开(公告)日：2017-08-29

申请号：US14401691

申请日：2013-04-18

Applicant: SYMRISE AG

Inventor： Rita Lages , Hubert Loges , Arnold Machinek , Gabriele Neuendorff , Erich Dilk , Heiko Oertling

IPC: A23L1/22 , A23L1/226 , A61K8/33 , A61K8/34 , A61K31/11 , A61K31/045 , A61Q11/00 , A23G4/06 , A23G3/36 , A23G3/38 , A61Q19/00 , A23G9/32 , A23L27/00 , A23L27/20

CPC classification number: A23L27/204 , A23G3/36 , A23G3/38 , A23G4/06 , A23G9/32 , A23L27/86 , A23L27/88 , A23V2002/00 , A61K8/33 , A61K8/34 , A61K31/045 , A61K31/11 , A61K2800/244 , A61Q11/00 , A61Q19/00

Abstract: A mixtures which contain (a) at least one phenylalkenal of formula (I) wherein R1 and R2 independently represent hydrogen, a methyl or phenyl group, R3 represents hydrogen, a phenyl group, alkenyl group or a linear or branched alkyl group with 1 to 5 carbon atoms, and the broken double lines independently represent a single bond or a double bond, and (b) at least one physiological cooling agent.

7.

发明申请
PREPARATIONS 审中-公开

公开(公告)号：US20180049449A1

公开(公告)日：2018-02-22

申请号：US15799180

申请日：2017-10-31

Applicant: Symrise AG

Inventor： Torsten Kulke , Sven Siegel , Michael Backes , Benoit Join , Hubert Loges , Günter Kindel

IPC: A23G4/06 , A61Q19/10 , A61Q17/04 , A61Q11/00 , A61Q5/00 , A61Q19/00 , A61K31/497 , A61K31/4436 , A61K31/426 , A61K31/42 , A61K31/4155 , A61K31/381 , A61K31/357 , A61K31/343 , A61K31/216 , A61K31/045 , A61K8/69 , A61K8/49 , A61K8/42 , A61K8/37 , A61K8/34 , A61K8/02

CPC classification number: A23G4/06 , A23L27/204 , A23L29/045 , A61K8/02 , A61K8/34 , A61K8/37 , A61K8/42 , A61K8/4986 , A61K8/69 , A61K31/045 , A61K31/216 , A61K31/343 , A61K31/357 , A61K31/381 , A61K31/4155 , A61K31/42 , A61K31/426 , A61K31/4436 , A61K31/497 , A61K2300/00 , A61K2800/244 , A61Q5/00 , A61Q11/00 , A61Q17/04 , A61Q19/00 , A61Q19/10

Abstract: Proposed are preparations, comprising special amides and menthol or menthol compounds or aromatic substances, characterized in that they have improved flavor and scent properties, and also that they allow the production of preparations, particularly emulsions with improved shelf life.

8.

发明申请
USE OF PHYSIOLOGICAL COOLING ACTIVE INGREDIENTS, AND AGENTS CONTAINING SUCH ACTIVE INGREDIENTS 审中-公开
Title translation: 使用生理冷却活性成分，以及含有此类活性成分的试剂

公开(公告)号：US20150086491A1

公开(公告)日：2015-03-26

申请号：US14533345

申请日：2014-11-05

Applicant: SYMRISE AG , BASF SE

Inventor： Thomas Subkowski , Michael Backes , Heiko Oertling , Arnold Machinek , Hubert Loges , Ulrike Simchen , Horst Surburg , Claus Bollschweiler , Jens Wittenberg , Wolfgang Siegel

IPC: C07D495/20 , A61K31/4375 , C07D491/147 , A61K31/506 , A23L1/30 , A61K31/5377 , A61K8/49 , A61Q11/00 , A24B13/00 , A24D1/00 , A61K31/438 , C07D401/04

CPC classification number: C07D495/20 , A23G3/36 , A23G4/06 , A23L2/52 , A23L27/2054 , A23L33/10 , A23V2002/00 , A24B13/00 , A24D1/002 , A61K8/49 , A61K8/4953 , A61K31/165 , A61K31/167 , A61K31/36 , A61K31/426 , A61K31/4375 , A61K31/438 , A61K31/4402 , A61K31/443 , A61K31/4741 , A61K31/4743 , A61K31/506 , A61K31/513 , A61K31/5377 , A61K2800/10 , A61K2800/244 , A61K2800/78 , A61Q11/00 , A61Q17/04 , A61Q19/00 , A61Q19/004 , C07C233/11 , C07C235/36 , C07C235/38 , C07C2601/14 , C07D213/75 , C07D317/60 , C07D401/04 , C07D405/12 , C07D491/147 , C07D495/22 , C09D5/1625 , D06M15/03 , D06M15/07 , D06M16/00

Abstract: The invention relates to a TRPM8 modulator for achieving a cooling effect on the skin or a mucous membrane.

Abstract translation: 本发明涉及一种用于实现对皮肤或粘膜的冷却作用的TRPM8调节剂。

9.

发明授权
Cooling preparations 有权

公开(公告)号：US10182584B2

公开(公告)日：2019-01-22

申请号：US14651490

申请日：2012-12-12

Applicant: Symrise AG

Inventor： Torsten Kulke , Sven Siegel , Michael Backes , Benoit Join , Hubert Loges , Günter Kindel

IPC: A61K8/42 , A61K8/49 , A61K8/02 , A61K8/37 , A61Q17/04 , A61Q5/00 , A61Q19/10 , A61Q11/00 , A23G4/06 , A61K8/34 , A61Q19/00 , A61K8/69 , A61K31/045 , A61K31/216 , A61K31/343 , A61K31/357 , A61K31/381 , A61K31/4155 , A61K31/42 , A61K31/426 , A61K31/4436 , A61K31/497 , A23L29/00 , A23L27/20

Abstract: Proposed are preparations, comprising special amides and menthol or menthol compounds or aromatic substances, characterized in that they have improved flavor and scent properties, and also that they allow the production of preparations, particularly emulsions with improved shelf life.