利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

70 条记录 (耗时 0.047 秒)

    2-(cyclic amino)-pyrimidone derivatives
    6.
    发明授权
    2-(cyclic amino)-pyrimidone derivatives 失效
    2-（环状氨基） - 嘧啶酮衍生物

    公开(公告)号：US08569294B2

    公开(公告)日：2013-10-29

    申请号：US12282396

    申请日：2007-03-14

    申请人： Kenji Fukunaga ,  Toshiyuki Kohara ,  Kazutoshi Watanabe ,  Yoshihiro Usui ,  Fumiaki Uehara ,  Satoshi Yokoshima ,  Daiki Sakai ,  Shin-ichi Kusaka ,  Kazuki Nakayama

    发明人： Kenji Fukunaga ,  Toshiyuki Kohara ,  Kazutoshi Watanabe ,  Yoshihiro Usui ,  Fumiaki Uehara ,  Satoshi Yokoshima ,  Daiki Sakai ,  Shin-ichi Kusaka ,  Kazuki Nakayama

    IPC分类号： A61K31/535

    CPC分类号： C07D413/14 ,  C07D401/04 ,  C07D401/14 ,  C07D403/14 ,  C07D409/14 ,  C07D453/06 ,  C07D493/04

    摘要： A compound represented by the formula (I), an optically active isomer thereof, or a pharmaceutical acceptable salt thereof: wherein R2 represents a hydrogen or the like; R3 represents methyl group or the like; R20 represents a halogen atom or the like; q represents an integer of 0 to 3; Z represent nitrogen atom, CH, or the like; R4 represents hydrogen or the like; R5 represents hydrogen or the like; R6 represents a substituted alkyloxy and the like; p represents an integer of 0 to 3; X represents bond, CH2, oxygen atom, NH, or the like; any one or more of R5 and R6, R5 and R4, R6 and R4, X and R5, X and R4, X and R6, and R6 and R6 may combine to each other to form a ring, which is used for preventive and/or therapeutic treatment of a disease caused by tau protein kinase 1 hyperactivity such as a neurodegenerative diseases (e.g. Alzheimer disease).

    摘要翻译： 由式（I）表示的化合物或其光学活性异构体或其药学上可接受的盐：其中R2表示氢等; R3表示甲基等; R 20表示卤素原子等; q表示0〜3的整数， Z表示氮原子，CH等; R4表示氢等; R5表示氢等; R6表示取代的烷氧基等; p表示0〜3的整数， X表示键，CH2，氧原子，NH等; R 5和R 6，R 5和R 4，R 6和R 4，X和R 5，X和R 4，X和R 6以及R 6和R 6中的任何一个或多个可以彼此结合形成环，其用于预防和/ 或治疗由tau蛋白激酶1多动症如神经变性疾病（例如阿尔茨海默病）引起的疾病。

    Substituted Ethynyl Gold-Nitrogen Containing Heterocyclic Carbene Complex and Organic Electroluminescent Device Using the Same
    10.
    发明申请
    Substituted Ethynyl Gold-Nitrogen Containing Heterocyclic Carbene Complex and Organic Electroluminescent Device Using the Same 有权
    含有杂环碳烯复合物的取代乙炔基金 - 氮和使用其的有机电致发光器件

    公开(公告)号：US20090091243A1

    公开(公告)日：2009-04-09

    申请号：US11883320

    申请日：2006-01-31

    申请人： Osamu Fujimura ,  Kenji Fukunaga ,  Takashi Honma ,  Toshikazu Machida ,  Takeshi Takahashi

    发明人： Osamu Fujimura ,  Kenji Fukunaga ,  Takashi Honma ,  Toshikazu Machida ,  Takeshi Takahashi

    IPC分类号： H01L51/54 ,  C07F19/00

    CPC分类号： H01L51/0084 ,  C07F1/00 ,  C09K11/06 ,  C09K2211/1007 ,  C09K2211/1029 ,  C09K2211/1044 ,  C09K2211/188 ,  H01L51/5012 ,  H01L51/5048 ,  H05B33/14 ,  Y10S428/917

    摘要： The present invention provides a substituted ethynyl gold-nitrogen containing heterocyclic carbene complex represented by the general formula (1): wherein L represents a nitrogen containing heterocyclic carbene ligand; and X represents an alkyl group, a cycloalkyl group, an aryl group, an aralkyl group or a heterocyclic group; in which one or more hydrogen atoms on the carbon atom(s) of X may be replaced by a halogen atom, an alkyl group, a cycloalkyl group, an alkenyl group, an aryl group, an aralkyl group, an alkoxy group, an aryloxy group, a dialkylamino group, an acyl group or an arylcarbonyl group; and, when more than one hydrogen atom on the carbon atom(s) of X is replaced by the alkyl group, the alkenyl group, the aryl group, the aralkyl group, the alkoxy group, the aryloxy group, the dialkylamino group, the acyl group or the arylcarbonyl group, the adjacent groups may be bonded together to form a ring, a method for preparing the same, and an organic electroluminescent device comprising the substituted ethynyl gold-nitrogen containing heterocyclic carbene complex in at least one organic compound thin layer.

    摘要翻译： 本发明提供由通式（1）表示的取代的含乙​​炔基金 - 氮的杂环卡宾络合物：其中L表示含氮杂环卡宾配体; X表示烷基，环烷基，芳基，芳烷基或杂环基; 其中X的碳原子上的一个或多个氢原子可以被卤素原子，烷基，环烷基，烯基，芳基，芳烷基，烷氧基，芳氧基 基团，二烷基氨基，酰基或芳基羰基; 并且当X的碳原子上的多于一个氢原子被烷基取代时，烯基，芳基，芳烷基，烷氧基，芳氧基，二烷基氨基，酰基 基团或芳基羰基，相邻基团可以键合在一起形成环，其制备方法和在至少一个有机化合物薄层中包含取代的含乙​​炔基金 - 氮的杂环卡宾络合物的有机电致发光器件。