公开(公告)号：US09835598B2

公开(公告)日：2017-12-05

申请号：US14012227

申请日：2013-08-28

Applicant: SHIMADZU CORPORATION

Inventor： Masato Watanabe ,  Masahide Gunji

IPC: G01N30/30 ,  G01N30/62

CPC classification number: G01N30/30 ,  Y10T137/6416 ,  G01N2030/626

Abstract: A heat insulating member 13 is provided on the outer circumference of a connection pipe 11. The heat insulating member 13 includes: a tube 12; and an air layer 15 between the connection pipe 11 and the tube 12. Accordingly, it is possible to always keep the temperature of a sample component at the time of detection by a detector constant and thus prevent an influence of the temperature on an output result of the detector, in a low flow rate analysis using a modularized column unit and a modularized detection unit.

公开(公告)号：US10739249B1

公开(公告)日：2020-08-11

申请号：US16184515

申请日：2019-02-04

Applicant: Shimadzu Corporation

Inventor： Masahide Gunji

IPC: G01N21/01 ,  G01N21/25 ,  G01N21/27

Abstract: The flow cell is composed of a cell block and a cell holder. The cell block is light transmittable and is provided with a plurality of cells communicated with each other and mutually different in optical path length and an inlet and an outlet communicated with the cell. The plurality of cells include a short optical path length cell having an optical path length of 100 μm or less. The short optical path length cell is constituted by a groove formed on an inner joining surface of a plurality of laminated light transmitting substrates. The optical path length of the short optical path length cell is defined by a depth of the groove. The cell holder is configured to accommodate the cell block therein, and is provided with an incident window for allowing light to enter the cell block and an emission window for emitting the light transmitted through the cell block.

公开(公告)号：US11933771B2

公开(公告)日：2024-03-19

申请号：US17413808

申请日：2018-12-20

Applicant: SHIMADZU CORPORATION

Inventor： Hiroyuki Minato ,  Masahide Gunji

IPC: G01N30/74 ,  G01N21/76 ,  G01N30/02 ,  G01N30/06 ,  G01N30/84 ,  G01N30/86

CPC classification number: G01N30/74 ,  G01N30/8631 ,  G01N21/76 ,  G01N2030/027 ,  G01N30/06 ,  G01N30/84 ,  G01N30/86

Abstract: A first liquid sending controller of an analysis control device controls a first liquid sender such that a mobile phase is supplied to a fluorescence detector through an analysis column and a junction during an analysis of a sample. A sample introduction controller controls a sample introducer such that the sample is introduced into a mobile phase by the sample introducer at a position farther upstream than the analysis column during the analysis of the sample. The second liquid sending controller causes a second liquid sender to start supplying a fluorescent reaction liquid such that the fluorescent reaction liquid arrives at the junction later than a point in time at which supply of the mobile phase starts and before the sample introduced into the mobile phase arrives at the junction during the analysis of the sample. A generator generates a chromatogram based on an output signal of the fluorescence detector during the analysis of the sample.

公开(公告)号：US11774462B2

公开(公告)日：2023-10-03

申请号：US16479700

申请日：2018-01-30

Applicant: SHIMADZU CORPORATION

Inventor： Masahide Gunji

IPC: G01N35/10 ,  C12M1/00 ,  G01N35/00 ,  G01N35/08 ,  G01N1/00 ,  G01N30/20 ,  G01N30/24

CPC classification number: G01N35/10 ,  C12M47/00 ,  G01N35/1004 ,  G01N1/00 ,  G01N30/20 ,  G01N30/24 ,  G01N35/08 ,  G01N2035/00475

Abstract: In a pre-processing system, a state in which a sample dispensing probe 20a and a syringe pump 81 communicate with each other through a channel 91 and a state in which the sample dispensing probe 20a and a culture tank 301 communicate with each other through the channels 91, 93, and 94 can be switched by operation of the three-way valves 82 and 83. For this reason, the liquid sample in the culture tank 301 can be automatically discharged from the sample dispensing probe 20a without requiring the user to directly sample the liquid sample. As a result, in the pre-processing system, the user's manual sampling work can be omitted, and the user's work can be simplified.

公开(公告)号：US10060795B2

公开(公告)日：2018-08-28

申请号：US15550006

申请日：2015-02-09

Applicant: Shimadzu Corporation

Inventor： Masahide Gunji ,  Akira Noda ,  Kensuke Otake

IPC: G01J3/28 ,  G01J3/36 ,  G01J3/42 ,  G01J3/12

CPC classification number: G01J3/36 ,  G01J3/12 ,  G01J3/28 ,  G01J3/2803 ,  G01J3/42

Abstract: A problem addressed by the present invention is to reduce the influence of stray light incident on each light-receiving element in the case of receiving each wavelength of light using a plurality of light-receiving elements. The multichannel spectrophotometer according to the present invention is a detector for simultaneously detecting the entirety of wavelength-dispersed light obtained by introducing light from a sample to a light-dispersing element (16) and dispersing this light into wavelengths by the light-dispersing element (16), including: a multichannel-type detector (17) including a plurality of light-receiving elements arranged in a one-dimensional form in a wavelength-dispersing direction of the light-dispersing element; a light amount calculator (221) for calculating the amount of light from a detection signal of each of the plurality of light-receiving elements (PD); a spectrum creator (222) for creating, from the amounts of light calculated by the light amount calculator (221), a spectrum showing a relationship between wavelength and the amount of light; and a computing section (224) for estimating, from the spectrum, the amount of stray light incident on each light-receiving element (PD) and correcting the spectrum by subtracting, from the amount of wavelength-dispersed light incident on each light-receiving element, the amount of stray light.

公开(公告)号：US12105069B2

公开(公告)日：2024-10-01

申请号：US17438421

申请日：2019-10-16

Applicant: SHIMADZU CORPORATION

Inventor： Tomohiro Gomi ,  Daisuke Kitabayashi ,  Shinya Imamura ,  Keisuke Ogawa ,  Masataka Nikko ,  Masahide Gunji

IPC: G01N30/86 ,  G01N30/02 ,  G01N30/32

CPC classification number: G01N30/8658 ,  G01N30/32 ,  G01N2030/027

Abstract: A liquid sending failure detector acquires periodically a liquid sending pressure of a liquid sending mechanism consecutively sends liquid using at least one plunger pump that sends liquid by reciprocally driving a plunger such that a fluctuation is read in one driving period of the liquid sending mechanism, and detect a liquid sending failure of the liquid sending mechanism using an acquired liquid sending pressure. The liquid sending failure detector executes a pulsation detection step of obtaining a fluctuation range of the liquid sending pressure in a certain driving period of the liquid sending mechanism and detecting pulsation on a condition that a count of consecutive periods in which the fluctuation range exceeds a predetermined reference value exceeds a predetermined reference count, and a liquid sending failure detection step of detecting a liquid sending failure of the liquid sending mechanism when the pulsation is detected in the pulsation detection step.

公开(公告)号：US09354114B2

公开(公告)日：2016-05-31

申请号：US14083664

申请日：2013-11-19

Applicant: SHIMADZU CORPORATION

Inventor： Masahide Gunji

IPC: G01J3/28 ,  G01J3/18 ,  G01J3/02 ,  G01N30/74 ,  G01N21/3577 ,  G01N21/85

CPC classification number: G01J3/2803 ,  G01J3/0262 ,  G01J3/18 ,  G01J2003/2813 ,  G01N21/3577 ,  G01N21/85 ,  G01N30/74

Abstract: A spectrophotometer in which a normal plane to a diffraction grating is inclined with respect to an optical axis of an incident light passing through a slit, the normal plane to the diffraction grating passing through an intersection point between the optical axis of the incident light i and a grating surface of the diffraction grating. The diffraction grating and a photodiode array PDA are placed such that the photodiode array PDA is parallel to the normal plane to the diffraction grating and that a normal plane to the photodiode array PDA includes a line that is symmetrical to the optical axis of the incident light i about the normal plane to the diffraction grating.

Abstract translation: 一种分光光度计，其中衍射光栅的法向平面相对于通过狭缝的入射光的光轴倾斜，衍射光栅的法线平面通过入射光i的光轴和 衍射光栅的光栅表面。 衍射光栅和光电二极管阵列PDA被放置成使得光电二极管阵列PDA平行于衍射光栅的法向平面，并且与光电二极管阵列PDA的法向平面包括与入射光的光轴对称的线 我关于衍射光栅的正常平面。

公开(公告)号：US11506640B2

公开(公告)日：2022-11-22

申请号：US16485195

申请日：2018-01-26

Applicant: SHIMADZU CORPORATION

Inventor： Kengo Aoki ,  Masahide Gunji

IPC: G01N30/16

Abstract: Obtaining sufficient suppression effect of channel diffusion and stably transferring solution are made possible even in a piping having an extremely small inner diameter used for an analysis apparatus such as an HPLC. A piping device for an analysis apparatus includes a piping equipped with a folded shape that suppresses inner channel diffusion, and a member directly or indirectly in contact with the piping from at least one side to support the piping to suppress deformation of the folded shape.

公开(公告)号：US20220314177A1

公开(公告)日：2022-10-06

申请号：US17684062

申请日：2022-03-01

Applicant: CKD Corporation ,  Shimadzu Corporation ,  Shinwa Chemical Industries Ltd.

Inventor： Shinichi Nitta ,  Hiroshi Itafuji ,  Mitsuyoshi Ohsaki ,  Masahide Gunji ,  Hiroshi Kobayashi ,  Katsuya Okumura

IPC: B01F33/301 ,  B01F33/3039 ,  B01F25/422 ,  B01F35/00 ,  B01F35/42

Abstract: A micromixer includes: a first channel plate where a first channel and a plurality of first branch channels are each formed by a non-through groove in a front surface, and a first confluence channel is formed by a non-through groove in a rear surface, and includes a first communication channel that communicates the first branch channels with the first confluence channel; a first lid plate that covers the front surface; a second channel plate where a second confluence channel is formed by a non-through groove in the front surface, and a second channel and a plurality of second branch each formed by a non-through groove in the rear surface, and includes a second communication channel that communicates the second branch channels with the second confluence channel; and a second lid plate that covers the rear surface of the second channel plate.

公开(公告)号：US11408818B2

公开(公告)日：2022-08-09

申请号：US16490979

申请日：2017-11-27

Applicant: Shimadzu Corporation

Inventor： Masahide Gunji

IPC: G01N21/05 ,  F16J15/10 ,  G01N21/64

Abstract: A gasket sandwiched between a flow cell and a joint member has, in a main flat surface, an inlet communication hole for communicating between an inlet hole of the flow cell and an inlet flow path of the joint member and an outlet communication hole for communicating between an outlet hole of the flow cell and an outlet flow path of the joint member. Furthermore, a deformation absorbing structure for absorbing deformation of the gasket is provided between the inlet communication hole and the outlet communication hole in the main flat surface of the gasket.