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1.发明授权
公开(公告)号：US4894343A
公开(公告)日：1990-01-16
申请号：US122269
申请日：1987-11-18
CPC分类号： C12N13/00 , C12M23/20 , C12M35/02 , G01N2015/149
摘要： There are disclosed a chamber plate for use in cell fusion comprising a plate of single crystal silicon on which a plurality of chambers for holding at least a pair of unit cells are formed in array, said chamber having at the bottom a plate having slits which do not pass cells to be held; and a process for producing a chamber plate for use in cell fusion which comprises forming chambers for holding cells in a plate of single crystal silicon by anisotropic etching or isotropic etching by chemical etching.
摘要翻译： 公开了一种用于细胞融合的室板，其包括单晶硅板，其上形成有用于保持至少一对单元电池的多个室，所述室在底部具有切口的板 不通过细胞被保持; 以及用于生产用于细胞融合的室板的方法，其包括通过各向异性蚀刻或通过化学蚀刻的各向同性蚀刻形成用于将单元硅保持在单元硅板中的室。
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公开(公告)号：US4750364A
公开(公告)日：1988-06-14
申请号：US920426
申请日：1986-10-20
申请人： Yoshio Kawamura , Kazuo Sato , Tsuneo Terasawa , Shinji Tanaka
发明人： Yoshio Kawamura , Kazuo Sato , Tsuneo Terasawa , Shinji Tanaka
IPC分类号： G01C19/56 , G01C19/5621 , G01C19/5628 , G01P15/097 , G01P15/10 , G01P15/125 , G01P15/08 , G01P9/04
CPC分类号： G01P15/097 , G01C19/5607 , G01P15/14
摘要： The specification discloses an angular velocity and acceleration sensor in which a tuning-fork oscillator is vibrated on the main driven vibrating axis and displacement on an axis which is parallel to the main driven vibrating axis or displacement which crosses it at right angles is detected so that at least one of angular velocity and acceleration on an axis which is parallel to the main driven vibrating axis or which crosses it at right angles may be detected. The sensor is characterized in that vibrating reeds of the tuning-fork oscillator are so formed that the spring constant of the vibrating reeds on the main driven vibrating axis is substantially equal to that on the axis which crosses the main driven vibrating axis at right angles.
摘要翻译： 本说明书公开了一种角速度和加速度传感器，其中音叉振荡器在主驱动振动轴上振动，并且检测到平行于主驱动振动轴的轴线的位移或与其直角穿过的轴的位移，使得 可以检测在与主驱动振动轴平行的轴上的角速度和加速度中的至少一个，或者以直角与其相交。 传感器的特征在于，音叉振荡器的振动片形成为使得主从动振动轴上的振动片的弹簧常数基本上等于与主驱动振动轴线成直角相交的轴线的弹簧常数。
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公开(公告)号：US5308757A
公开(公告)日：1994-05-03
申请号：US742419
申请日：1991-08-08
申请人： Yoshio Kawamura , Yoshu Yoshiba , Shinji Tanaka , Kazuo Sato , Jiro Kikuchi , Kahoru Takahashi
发明人： Yoshio Kawamura , Yoshu Yoshiba , Shinji Tanaka , Kazuo Sato , Jiro Kikuchi , Kahoru Takahashi
IPC分类号： C12M1/00 , C12M1/34 , C12M3/00 , C12N5/00 , C12N5/04 , C12Q1/06 , G01N33/487 , C12Q1/02 , C12M1/20
CPC分类号： C12M41/46 , C12Q1/06 , Y10S436/807 , Y10S436/809
摘要： In determining the effectiveness of parameters on cells, after treatment of the cells with one or more selected parameters, the results of the treatment can be quickly determined by measuring the number n.sub.0 of cells having a predetermined cell form, subsequently mechanically stressing the cells for a sufficient period of time t to change the cell form substantially, thereafter again measuring the number n of cells having the predetermined cell form, and determining the cell viability .tau.defined by .tau.=t/1n(n.sub.0 /n).
摘要翻译： 在确定细胞参数的有效性时，在用一个或多个所选参数处理细胞后，可以通过测量具有预定细胞形式的细胞的数目n0来快速确定治疗结果，随后将细胞机械胁迫 足够的时间t以基本上改变细胞形式，然后再次测量具有预定细胞形式的细胞的数目n，以及确定由tau = t / 1n（n0 / n）定义的细胞存活力τ。
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公开(公告)号：US5183744A
公开(公告)日：1993-02-02
申请号：US425028
申请日：1989-10-23
申请人： Yoshio Kawamura , Shinji Tanaka , Kazuo Sato , Kenko Uchida , Hiroyuki Kohida
发明人： Yoshio Kawamura , Shinji Tanaka , Kazuo Sato , Kenko Uchida , Hiroyuki Kohida
摘要： A method and an apparatus for the treatment of particles or biological cells are disclosed, wherein the particles or cells are precipitated or ascended depending on the specific gravity of a liquid used, and the particles or cells are handled with the aid of a holding plate. A method and an apparatus for the fusion of particles or cells are also disclosed, wherein an electric voltage is loaded on a position between electrodes in a microchamber to fuse the particles or cells held in the microchamber.
摘要翻译： 公开了一种用于处理颗粒或生物细胞的方法和装置，其中所述颗粒或细胞根据所用液体的比重而沉淀或上升，并且借助于保持板处理颗粒或细胞。 还公开了一种用于熔化颗粒或细胞的方法和装置，其中电压被加载在微室中的电极之间的位置，以熔化保持在微室中的颗粒或细胞。
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公开(公告)号：US5284179A
公开(公告)日：1994-02-08
申请号：US890711
申请日：1992-05-29
申请人： Mitsuhiro Shikida , Kazuo Sato , Yoshio Kawamura , Shinji Tanaka , Yasuaki Horiuchi , Akira Koide , Toshimitsu Miyada
发明人： Mitsuhiro Shikida , Kazuo Sato , Yoshio Kawamura , Shinji Tanaka , Yasuaki Horiuchi , Akira Koide , Toshimitsu Miyada
CPC分类号： F16K99/0001 , F04B43/043 , F15C5/00 , F16K99/0015 , F16K99/0051 , F16K2099/0074 , F16K2099/0082 , Y10S251/901 , Y10T137/6416 , Y10T137/87249
摘要： Disclosed is a gas valve capable of switching gases to be introduced within a vacuum chamber with high speed thereby enhancing the controllability of the composion of a semiconducting thin film growing on a substrate and shortening the time required for growth of the thin film. The gas valve comprises a bendable film between a pair of parallel plate electrodes whereby operating the film by an electrostatic force and opening and closing a port for releasing gas to a substrate mounted on the wall surface of a gas chamber and a port for exhausting an unnecessary gas to an exhaust passage. The gas valve is mounted in the vicinity of the substrate within the vacuum chamber for supplying a working gas in a minimum amount required for the film growth.
摘要翻译： 公开了一种能够以高速切换在真空室内被引入的气体的气阀，从而提高了生长在基板上的半导体薄膜的组合的可控性，并缩短了薄膜生长所需的时间。 气阀包括一对平行板电极之间的可弯曲膜，由此通过静电力操作膜，并且打开和关闭用于将气体释放到安装在气室的壁表面上的基板的端口和用于排出不必要的端口 气体到排气通道。 气体阀安装在真空室内的基板附近，用于以薄膜生长所需的最小量供应工作气体。
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公开(公告)号：US4895805A
公开(公告)日：1990-01-23
申请号：US235485
申请日：1988-08-24
申请人： Kazuo Sato , Shinji Tanaka , Yoshio Kawamura , Hiroyuki Kohida , Yoshihisa Hosoe , Masatoshi Sakurano
发明人： Kazuo Sato , Shinji Tanaka , Yoshio Kawamura , Hiroyuki Kohida , Yoshihisa Hosoe , Masatoshi Sakurano
摘要： Disclosed is a cell manipulating apparatus for conveying cells to a plurality of chambers provided in a chamber plate. The apparatus comprises a taking-up device adapted to take up cells to the respective taking up portions of a carrier plate placed in positions corresponding to those of said chambers in the chamber plate and a moving device adapted to move, relatively with respect to the chamber plate, the taking-up device to a position above the chamber plate. The taking-up portions may be effectively composed of pressure-controlled cavities or SiO.sub.2 films provided in the carrier plate.
摘要翻译： 公开了一种用于将电池输送到设置在室板中的多个室的电池操作装置。 该装置包括一个卷取装置，适用于将细胞吸收到放置在与腔室板中的所述腔室相对应的位置的载体板的相应卷取部分上，移动装置适于相对于腔室移动 将卷取装置放置在室板上方的位置。 卷取部分可以有效地由设置在承载板中的压力控制的空腔或SiO 2膜组成。
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公开(公告)号：US5346825A
公开(公告)日：1994-09-13
申请号：US910524
申请日：1992-07-08
CPC分类号： C12M35/02
摘要： The following invention relates to an apparatus and a method for improving the rate of cell fusion. Cells contained in chambers are prevented from adhering to the surface of the walls of a chamber in which they are contained by the pulse-like changes in fluid pressure, which causes the cells to separate from the surface of the chamber.
摘要翻译： 以下发明涉及提高细胞融合率的装置和方法。 包含在腔室中的细胞被流体压力的脉冲状变化阻止附着在容纳腔室的壁的表面上，这导致细胞与腔室的表面分离。
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公开(公告)号：US5154814A
公开(公告)日：1992-10-13
申请号：US253560
申请日：1988-10-05
CPC分类号： C12M35/02
摘要： A cell handling apparatus is provided with a device for moving cells which are held in chambers of the apparatus, at predetermined periods, preferably a device for generating pulse-like changes in fluid pressure of the chambers, so as to prevent the same portions of the cells from remaining in contact with the wall surfaces of the chambers over a predetermined period of time.
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公开(公告)号：US5380396A
公开(公告)日：1995-01-10
申请号：US138051
申请日：1993-10-19
申请人： Mitsuhiro Shikida , Kazuo Sato , Yoshio Kawamura , Shinji Tanaka , Yasuaki Horiuchi , Akira Koide , Toshimitsu Miyada
发明人： Mitsuhiro Shikida , Kazuo Sato , Yoshio Kawamura , Shinji Tanaka , Yasuaki Horiuchi , Akira Koide , Toshimitsu Miyada
CPC分类号： F16K99/0001 , F04B43/043 , F15C5/00 , F16K99/0015 , F16K99/0051 , F16K2099/0074 , F16K2099/0082 , Y10S251/901 , Y10T137/6416 , Y10T137/87249
摘要： Disclosed is a gas valve capable of switching gases to be introduced within a vacuum chamber with high speed thereby enhancing the controllability of the composion of a semiconducting thin film growing on a substrate and shortening the time required for growth of the thin film. The gas valve comprises a bendable film between a pair of parallel plate electrodes whereby operating the film by an electrostatic force and opening and closing a port for releasing gas to a substrate mounted on the wall surface of a gas chamber and a port for exhausting an unnecessary gas to an exhaust passage. The gas valve is mounted in the vicinity of the substrate within the vacuum chamber for supplying a working gas in a minimum amount required for the film growth.
摘要翻译： 公开了一种能够以高速切换在真空室内被引入的气体的气阀，从而提高了生长在基板上的半导体薄膜的组合的可控性，并缩短了薄膜生长所需的时间。 气阀包括一对平行板电极之间的可弯曲膜，由此通过静电力操作膜，并且打开和关闭用于将气体释放到安装在气室的壁表面上的基板的端口和用于排出不必要的端口 气体到排气通道。 气体阀安装在真空室内的基板附近，用于以薄膜生长所需的最小量供应工作气体。
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公开(公告)号：US5003516A
公开(公告)日：1991-03-26
申请号：US336685
申请日：1989-04-12
申请人： Kazuo Sato , Hiroshi Kanda , Shigeo Kato , Kuninori Imai , Takeji Shiokawa , Shinji Tanaka , Isao Ishikawa , Harumasa Onozato , Hisayoshi Hashimoto , Morio Tamura , Kazuyoshi Hatano , Fujio Sato , Ken Ichiryuu , Kiyoshi Tanaka , Takao Kawanuma
发明人： Kazuo Sato , Hiroshi Kanda , Shigeo Kato , Kuninori Imai , Takeji Shiokawa , Shinji Tanaka , Isao Ishikawa , Harumasa Onozato , Hisayoshi Hashimoto , Morio Tamura , Kazuyoshi Hatano , Fujio Sato , Ken Ichiryuu , Kiyoshi Tanaka , Takao Kawanuma
摘要： An ultrasonic probe comprising an acoustic lens (20) having a concave lens surface (21) formed on one side of a lens body, and a piezoelectric transducer (23) disposed on the other side of the acoustic lens, ultrasonic waves generated by applying voltage to the piezoelectric transducer being focused through the lens surface to detect the reflected waves of the ultrasonic waves from a sample (26) by the piezoelectric transducer for obtaining information about the surface or interior of the sample. The lens surface (21) of the acoustic lens (20) is defined by an etch profile (15) formed by etching a substrate material (11) which makes up the lens body.
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