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1.Use of low-volatility pyrazole derivatives having hydrophilic groups as nitrification inhibitors 失效
标题翻译: 使用具有亲水基团的低挥发性吡唑衍生物作为硝化抑制剂公开(公告)号:US5972064A
公开(公告)日:1999-10-26
申请号:US875755
申请日:1997-08-06
IPC分类号: C05G3/08 , C07D231/12 , C07D231/16 , C09K17/14 , C09K101/00 , C07C11/08 , C07D231/20 , C07D231/22
CPC分类号: C07D231/12 , C05G3/08 , C07D231/16 , Y02P60/218
摘要: The present invention provides pyrazole compounds which are useful as nitrification inhibitors.
摘要翻译: PCT No.PCT / EP96 / 00319 Sec。 371日期:1997年8月6日 102(e)日期1997年8月6日PCT 1996年1月26日PCT公布。 出版物WO96 / 24566 日期:1996年8月15日本发明提供可用作硝化抑制剂的吡唑化合物。
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2.Nitrification inhibitors and the use of polyacids to treat mineral fertilizers containing a nitrification inhibitor 有权
标题翻译: 硝化抑制剂和多酸用于处理含有硝化抑制剂的矿物肥料公开(公告)号:US06139596A
公开(公告)日:2000-10-31
申请号:US230841
申请日:1999-09-24
申请人: Thomas Barth , Norbert Rieber , Randall Evan Gold , Jurgen Dressel , Klaus Erhardt , Klaus Horchler von Locquengh , Edgar Leibold , Stefan Rittinger
发明人: Thomas Barth , Norbert Rieber , Randall Evan Gold , Jurgen Dressel , Klaus Erhardt , Klaus Horchler von Locquengh , Edgar Leibold , Stefan Rittinger
IPC分类号: C05F3/00 , C05G3/00 , C05G3/08 , C05G5/00 , C07D231/12 , C07D231/16 , C07D321/12 , C07D521/00 , C05C9/00 , C07D231/10
CPC分类号: C07D231/12 , C05F3/00 , C05G3/08 , C07D231/16 , C07D233/56 , C07D249/08 , Y02P20/145 , Y02P60/218 , Y10S71/902
摘要: The use of inorganic or organic polyacids for the treatment of inorganic fertilizers, in particular the use of the polyacids as a mixture with at least one nitrification inhibitor for the treatment of inorganic fertilizers; the use of selected pyrazole derivatives as nitrification inhibitor in inorganic fertilizers and also as stabilizers of liquid manure or liquid fertilizer formulations, as well as the corresponding treated inorganic fertilizers per se; and novel pyrazole derivatives which can be used as nitrification inhibitors in inorganic fertilizers and also as stabilizers of liquid manure or liquid fertilizer formulations are described.
摘要翻译: PCT No.PCT / EP97 / 04278第 371 1999年9月24日第 102(e)1999年9月24日PCT PCT 1997年8月6日PCT公布。 公开号WO98 / 05607 日期1998年2月12日无机或有机多元酸用于无机肥料的处理,特别是使用多酸作为与至少一种硝化抑制剂的混合物用于无机肥料的处理; 在无机肥料中使用选择的吡唑衍生物作为硝化抑制剂,还用作液体肥料或液体肥料配方的稳定剂,以及相应的经处理的无机肥料本身; 并且描述了可用作无机肥料中的硝化抑制剂以及作为液体肥料或液体肥料制剂的稳定剂的新型吡唑衍生物。
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3.
公开(公告)号:US5414008A
公开(公告)日:1995-05-09
申请号:US80854
申请日:1993-06-21
申请人: Ulrich E. Muller , Jurgen Dressel , Peter Fey , Rudolf H. Hanko , Walter Hubsch , Thomas Kramer , Matthias Muller-Gliemann , Martin Beuck , Stanislav Kazda , Andreas Knorr , Johannes-Peter Stasch , Stefan Wohlfeil
发明人: Ulrich E. Muller , Jurgen Dressel , Peter Fey , Rudolf H. Hanko , Walter Hubsch , Thomas Kramer , Matthias Muller-Gliemann , Martin Beuck , Stanislav Kazda , Andreas Knorr , Johannes-Peter Stasch , Stefan Wohlfeil
IPC分类号: A61K31/415 , A61P43/00 , C07D233/54 , C07D233/64 , C07D233/66 , C07D233/68 , C07D233/90 , C07D403/10
CPC分类号: C07D233/64 , C07D233/68 , C07D403/10
摘要: Imidazolyl-substituted phenylpropionic and cinnamic acid derivatives are prepared by reacting appropriate benzyl compounds with imidazoles and optionally varying the substituents. The imidazolyl-substituted phenylpropionic and cinnamic acid derivatives can be used as active compounds in medicaments, in particular in the treatment of arterial hypertension and atherosclerosis.
摘要翻译: 咪唑基取代的苯丙酸和肉桂酸衍生物通过使适当的苄基化合物与咪唑反应并任选改变取代基来制备。 咪唑基取代的苯丙酸和肉桂酸衍生物可用作药物中的活性化合物,特别是用于治疗动脉高血压和动脉粥样硬化。
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公开(公告)号:US5407948A
公开(公告)日:1995-04-18
申请号:US239197
申请日:1994-05-06
申请人: Peter Fey , Walter Hubsch , Jurgen Dressel , Rudolf Hanko , Thomas Kramer , Ulrich Muller , Matthias Muller-Gliemann , Martin Beuck , Hilmar Bischoff , Stefan Wohlfeil , Dirk Denzer , Stanislav Kazda , Johannes-Peter Stasch , Andreas Knorr , Siegfried Zaiss
发明人: Peter Fey , Walter Hubsch , Jurgen Dressel , Rudolf Hanko , Thomas Kramer , Ulrich Muller , Matthias Muller-Gliemann , Martin Beuck , Hilmar Bischoff , Stefan Wohlfeil , Dirk Denzer , Stanislav Kazda , Johannes-Peter Stasch , Andreas Knorr , Siegfried Zaiss
IPC分类号: A61K31/44 , A61K31/4402 , A61K31/4418 , A61K31/4427 , A61K31/50 , A61K31/53 , A61P9/10 , A61P9/12 , A61P43/00 , C07D213/60 , C07D213/64 , C07D213/71 , C07D213/76 , C07D213/78 , C07D213/79 , C07D401/10 , C07D401/14
CPC分类号: C07D401/14
摘要: Substituted mono- and bipyridylmethylpyridones are prepared either by reaction of pyridones with mono- or bipyridylmethylhalogen compounds or by reaction of pyridone-substituted halogenopyridines with tetrazolylphenylboronic acids. The substituted mono- and bipyridylmethylpyridones can be employed as active compounds in medicaments, in particular for the treatment of arterial hypertension and atherosclerosis.
摘要翻译: 取代的单 - 和二吡啶基甲基吡啶酮通过吡啶酮与单吡啶基或联吡啶甲基卤化合物的反应或通过吡啶酮取代的卤代吡啶与四唑基苯基硼酸的反应来制备。 取代的单吡啶基和联吡啶基甲基吡啶酮可用作药物中的活性化合物,特别是用于治疗动脉高血压和动脉粥样硬化。
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公开(公告)号:US5318980A
公开(公告)日:1994-06-07
申请号:US18961
申请日:1993-02-18
申请人: Rudolf Hanko , Jurgen Dressel , Peter Fey , Walter Hubsch , Thomas Kramer , Ulrich E. Muller , Matthias Muller-Gliemann , Martin Beuck , Stanislav Kazda , Claudia Hirth-Dietrich , Andreas Knorr , Johannes-Peter Stasch , Stefan Wohlfeil , Ozkan Yalkinoglu
发明人: Rudolf Hanko , Jurgen Dressel , Peter Fey , Walter Hubsch , Thomas Kramer , Ulrich E. Muller , Matthias Muller-Gliemann , Martin Beuck , Stanislav Kazda , Claudia Hirth-Dietrich , Andreas Knorr , Johannes-Peter Stasch , Stefan Wohlfeil , Ozkan Yalkinoglu
IPC分类号: A61K31/415 , A61K31/40 , A61K31/4427 , A61K31/445 , A61P9/10 , A61P9/12 , A61P43/00 , C07D233/64 , C07D233/68 , C07D401/12 , C07D401/14 , C07D403/12 , C07D403/14 , C07D413/12 , A61K31/535 , A61K31/495
CPC分类号: C07D401/12 , C07D233/68 , C07D403/12
摘要: Sulphonylbenzyl-substituted imidazoles can be prepared by first reacting imidazolylaldehydes with sulphonylbenzyl compounds and then oxidising or reducing the aldehyde function in the customary manner.The sulphonylbenzyl-substituted imidazoles can be used as active compounds in medicaments.
摘要翻译: 磺酰基苄基取代的咪唑可以通过首先使咪唑基醛与磺酰基苄基化合物反应,然后以常规方式氧化或还原醛官能团来制备。 磺酰苄基取代的咪唑可用作药物中的活性化合物。
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公开(公告)号:US4699983A
公开(公告)日:1987-10-13
申请号:US838780
申请日:1986-03-12
IPC分类号: C05G3/08 , C07D213/73 , C07D401/04 , A01N43/40 , C07D211/72
CPC分类号: C07D213/73 , C05G3/08 , C07D401/04 , Y02P60/218
摘要: 2-Amino-4-trichloromethylpyridine of the formula I ##STR1## The compound is an effective nitrification inhibitor.
摘要翻译: 式I的2-氨基-4-三氯甲基吡啶(I)该化合物是有效的硝化抑制剂。
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7.Heterocyclically substituted phenylacetic acid derivatives and their use in medicaments 失效
标题翻译: 杂环取代的苯乙酸衍生物及其在药物中的应用公开(公告)号:US5776964A
公开(公告)日:1998-07-07
申请号:US609366
申请日:1996-03-01
申请人: Ulrich Muller , Klaus Mohrs , Jurgen Dressel , Rudolf Hanko , Walter Hubsch , Michael Matzke , Ulrich Niewohner , Siegfried Raddatz , Thomas Kramer , Matthias Muller-Gliemann , Hans-Peter Bellemann , Martin Beuck , Stanislav Kazda , Stefan Wohlfeil
发明人: Ulrich Muller , Klaus Mohrs , Jurgen Dressel , Rudolf Hanko , Walter Hubsch , Michael Matzke , Ulrich Niewohner , Siegfried Raddatz , Thomas Kramer , Matthias Muller-Gliemann , Hans-Peter Bellemann , Martin Beuck , Stanislav Kazda , Stefan Wohlfeil
IPC分类号: A61K31/40 , A61K31/41 , A61K31/415 , A61K31/4184 , A61P7/10 , A61P9/00 , A61P9/08 , A61P9/10 , A61P9/12 , A61P11/08 , A61P13/02 , A61P13/12 , A61P15/00 , A61P43/00 , C07D207/30 , C07D231/12 , C07D231/14 , C07D231/56 , C07D233/54 , C07D233/60 , C07D233/64 , C07D233/68 , C07D233/90 , C07D235/06 , C07D235/08 , C07D235/14 , C07D235/16 , C07D249/04 , C07D249/08 , C07D249/12 , C07D249/14 , C07D249/18 , C07D403/10 , C07D405/06 , C07D409/06 , C07D471/04 , C07D521/00 , C07D235/10 , C07D235/12
CPC分类号: C07D249/08 , C07D231/12 , C07D231/14 , C07D231/56 , C07D233/56 , C07D233/64 , C07D233/68 , C07D233/90 , C07D235/06 , C07D235/08 , C07D235/14 , C07D235/16 , C07D249/18 , C07D403/10 , C07D409/06 , C07D471/04
摘要: The invention relates to phenylacetic acid derivatives which are substituted by a five-membered nitrogen heterocycle bonded via an N atom. They are prepared by reaction of phenylacetic acid derivatives substituted with leaving groups with the appropriate nitrogen heterocycles and can be used as active substances in medicaments for the treatment of high blood pressure and atherosclerosis.
摘要翻译: 本发明涉及被通过N原子键合的五元氮杂环取代的苯乙酸衍生物。 它们通过用离去基团取代的苯乙酸衍生物与适当的氮杂环的反应制备,并且可以用作治疗高血压和动脉粥样硬化的药物中的活性物质。
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8.Heterocyclically substituted phenyl-cyclohexane-carboxylic acid derivatives 失效
标题翻译: 杂环取代的苯基 - 环己烷羧酸衍生物公开(公告)号:US5395840A
公开(公告)日:1995-03-07
申请号:US193835
申请日:1994-02-08
申请人: Ulrich E. Muller , Jurgen Dressel , Peter Fey , Rudolf H. Hanko , Walter Hubsch , Thomas Kramer , Matthias Muller-Gliemann , Martin Beuck , Stanisiav Kazda , Stefan Wohlfeil , Andreas Knorr , Johannes-Peter Stasch , Siegfried Zaiss
发明人: Ulrich E. Muller , Jurgen Dressel , Peter Fey , Rudolf H. Hanko , Walter Hubsch , Thomas Kramer , Matthias Muller-Gliemann , Martin Beuck , Stanisiav Kazda , Stefan Wohlfeil , Andreas Knorr , Johannes-Peter Stasch , Siegfried Zaiss
IPC分类号: A61K31/40 , A61K31/403 , A61K31/404 , A61K31/41 , A61K31/415 , A61K31/4184 , A61K31/4188 , A61K31/435 , A61P9/00 , A61P9/10 , A61P9/12 , A61P43/00 , C07D209/02 , C07D209/08 , C07D209/10 , C07D209/12 , C07D209/30 , C07D235/08 , C07D235/10 , C07D235/18 , C07D403/10 , C07D471/04
CPC分类号: C07D471/04
摘要: Heterocyclically substituted phenyl-cyclohexanecarboxylic acid derivatives are prepared by reacting appropriate heterocyclic compounds with cyclohexanebenzyl halides.The compounds can be employed as active compounds in medicaments for the treatment of arterial hypertension and atherosclerosis.
摘要翻译: 通过使适当的杂环化合物与环己烷苄基卤化物反应来制备杂环取代的苯基 - 环己烷羧酸衍生物。 该化合物可用作用于治疗动脉高血压和动脉粥样硬化的药物中的活性化合物。
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公开(公告)号:US5364942A
公开(公告)日:1994-11-15
申请号:US18964
申请日:1993-02-18
申请人: Rudolf Hanko , Jurgen Dressel , Peter Fey , Walter Hubsch , Thomas Kramer , Ulrich E. Muller , Matthias Muller-Gliemann , Martin Beuck , Stanislav Kazda , Claudia Hirth-Dietrich , Andreas Knorr , Johannes-Peter Stasch , Stefan Wohlfeil , Ozkan Yalkinoglu
发明人: Rudolf Hanko , Jurgen Dressel , Peter Fey , Walter Hubsch , Thomas Kramer , Ulrich E. Muller , Matthias Muller-Gliemann , Martin Beuck , Stanislav Kazda , Claudia Hirth-Dietrich , Andreas Knorr , Johannes-Peter Stasch , Stefan Wohlfeil , Ozkan Yalkinoglu
IPC分类号: A61K31/435 , A61K31/40 , A61K31/445 , A61K31/675 , A61P9/12 , A61P43/00 , C07D205/04 , C07D207/16 , C07D207/48 , C07D211/60 , C07D211/96 , C07D295/26 , C07D401/04 , C07D403/04 , C07D413/04 , C07D471/04 , C07F9/6561 , A61K31/415 , A61K31/44 , C07D471/06
CPC分类号: C07D295/26 , C07D207/48 , C07D211/96 , C07D471/04
摘要: Sulphonylbenzyl-substituted imidazopyridines can be prepared by reacting correspondingly substituted imidazopyridines with sulphonylbenzyl compounds. The sulphonylbenzyl-substituted imidazopyridines can be employed as active compounds in medicaments, in particular for the treatment of hypertension and atherosclerosis.
摘要翻译: 磺酰基苄基取代的咪唑并吡啶可以通过使相应取代的咪唑并吡啶与磺酰基苄基化合物反应来制备。 磺酰基苄基取代的咪唑并吡啶可用作药物中的活性化合物,特别是用于治疗高血压和动脉粥样硬化。
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公开(公告)号:US5352687A
公开(公告)日:1994-10-04
申请号:US25479
申请日:1993-03-03
申请人: Ulrich E. Muller , Matthias Muller-Gliemann , Jurgen Dressel , Peter Fey , Rudolf Hanko , Walter Hubsch , Thomas Kramer , Martin Beuck , Stanislav Kazda , Stefan Wohlfeil , Ozkan Yalkinoglu , Andreas Knorr , Johannes-Peter Stasch
发明人: Ulrich E. Muller , Matthias Muller-Gliemann , Jurgen Dressel , Peter Fey , Rudolf Hanko , Walter Hubsch , Thomas Kramer , Martin Beuck , Stanislav Kazda , Stefan Wohlfeil , Ozkan Yalkinoglu , Andreas Knorr , Johannes-Peter Stasch
IPC分类号: A61K31/415 , A61K31/44 , A61K31/4427 , A61K31/443 , A61P9/10 , A61P9/12 , A61P43/00 , C07D233/68 , C07D233/90 , C07D401/12 , C07D405/12 , C07D409/06 , A61K31/535 , A61K31/47 , C07D407/10 , C07D413/10
CPC分类号: C07D401/12 , C07D233/68 , C07D405/12
摘要: Substituted phenylacetamides can be prepared by reaction of appropriately substituted phenylacetic acids with imidazoles and subsequent amidation. The substituted phenylacetic acid derivatives can be employed in medicaments for the treatment of high blood pressure and atherosclerosis.
摘要翻译: 取代的苯基乙酰胺可以通过将适当取代的苯乙酸与咪唑反应并随后进行酰胺化来制备。 取代的苯乙酸衍生物可用于治疗高血压和动脉粥样硬化的药物中。
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