Combinatorial synthesis
    9.
    发明授权
    Combinatorial synthesis 失效
    组合综合

    公开(公告)号:US07491677B2

    公开(公告)日:2009-02-17

    申请号:US10611385

    申请日:2003-07-01

    IPC分类号: B01J21/04

    摘要: Methods are disclosed for providing a library of composite or novel composition samples on a support. The method involves depositing one or more components as concentration gradients on the surface of the support. The concentration gradients are placed on the support in the form of superimposed triangles which allow ready formation of composite or composition samples containing three or more components. The samples can be removed from the support by drilling out portions of the coated support so as to yield individual tablets containing the support with one or more component layers thereon. By using this method, a vast number of samples can be made.

    摘要翻译: 公开了用于在载体上提供复合或新型组合物样品的文库的方法。 该方法包括将一种或多种组分沉积在载体表面上作为浓度梯度。 浓度梯度以叠加三角形的形式放置在载体上,其允许容易地形成含有三种或更多种组分的复合材料或组合物样品。 可以通过钻出涂覆的支撑物的部分来从支撑体移除样品,以便产生包含其上具有一个或多个组分层的载体的单个片剂。 通过使用该方法,可以制造大量的样品。