公开(公告)号：US10301413B2

公开(公告)日：2019-05-28

申请号：US14698721

申请日：2015-04-28

Applicant: University of Washington

Inventor： Shaoyi Jiang ,  Shengfu Chen

IPC: A61K31/665 ,  C08F220/10 ,  A61K38/10 ,  C08F220/26 ,  C08F220/34 ,  B29C39/20 ,  C08L51/04 ,  C08F222/10

Abstract: Nonfouling copolymers and hydrogels comprising positively charged repeating units or latent positively charged repeating units and negatively charged units or latent positively charged units.

公开(公告)号：US09535062B2

公开(公告)日：2017-01-03

申请号：US14470775

申请日：2014-08-27

Applicant: University of Washington

Inventor： Shaoyi Jiang ,  Zheng Zhang ,  Shengfu Chen ,  Hana Vaisocherova

IPC: G01N33/545 ,  G01N33/543 ,  C08F122/22

CPC classification number: G01N33/545 ,  C08F122/22 ,  G01N33/54353

Abstract: Dual-functional nonfouling surfaces and materials, methods for making dual-functional nonfouling surfaces and materials, and devices that include dual-functional nonfouling surfaces and materials. The dual-functional surfaces are nonfouling surfaces that resist non-specific protein adsorption and cell adhesion. The dual-functional surfaces and materials include covalently coupled biomolecules (e.g., target binding partners) that impart specific biological activity thereto. The surfaces and materials are useful in medical diagnostics, biomaterials and bioprocessing, tissue engineering, and drug delivery.

Abstract translation: 双功能非结垢表面和材料，用于制造双功能非结垢表面和材料的方法，以及包括双功能非结垢表面和材料的装置。 双功能表面是抵抗非特异性蛋白质吸附和细胞粘附的非结垢表面。 双功能表面和材料包括向其赋予特定生物活性的共价偶联的生物分子（例如靶结合配偶体）。 表面和材料可用于医学诊断，生物材料和生物处理，组织工程和药物递送。

公开(公告)号：US20170174907A1

公开(公告)日：2017-06-22

申请号：US15394538

申请日：2016-12-29

Applicant: University of Washington

Inventor： Shaoyi Jiang ,  Yuting Li ,  Hong Xue ,  Shengfu Chen

IPC: C09D5/16 ,  B63B59/04 ,  C09D153/00 ,  C09D151/08 ,  C09D133/26 ,  C09D183/04

CPC classification number: C09D5/1637 ,  A61K31/785 ,  B63B59/04 ,  C09D5/16 ,  C09D5/1606 ,  C09D5/165 ,  C09D5/1656 ,  C09D5/1662 ,  C09D5/1668 ,  C09D5/1675 ,  C09D133/26 ,  C09D151/085 ,  C09D153/00 ,  C09D183/04 ,  Y10T428/31511 ,  Y10T428/3154 ,  Y10T428/31551 ,  Y10T428/31663 ,  Y10T428/31725 ,  Y10T428/31786 ,  Y10T428/31844 ,  Y10T428/31938 ,  Y10T428/31942 ,  Y10T442/10

Abstract: Marine coatings including cationic polymers hydrolyzable to nonfouling zwitterionic polymers, coated marine surfaces, and methods for making and using the marine coatings.

公开(公告)号：US20170108492A1

公开(公告)日：2017-04-20

申请号：US15396128

申请日：2016-12-30

Applicant: University of Washington

Inventor： Shaoyi Jiang ,  Zheng Zhang ,  Shengfu Chen ,  Hana Vaisocherova

IPC: G01N33/545 ,  G01N33/543 ,  C08F122/22

CPC classification number: G01N33/545 ,  C08F122/22 ,  G01N33/54353

Abstract: Dual-functional nonfouling surfaces and materials, methods for making dual-functional nonfouling surfaces and materials, and devices that include dual-functional nonfouling surfaces and materials. The dual-functional surfaces are nonfouling surfaces that resist non-specific protein adsorption and cell adhesion. The dual-functional surfaces and materials include covalently coupled biomolecules (e.g., target binding partners) that impart specific biological activity thereto. The surfaces and materials are useful in medical diagnostics, biomaterials and bioprocessing, tissue engineering, and drug delivery.

公开(公告)号：US09533006B2

公开(公告)日：2017-01-03

申请号：US13692958

申请日：2012-12-03

Applicant: University of Washington

Inventor： Shaoyi Jiang ,  Xuewei Xu ,  Yuting Li ,  Andrew Keefe ,  Hong Xue ,  Shengfu Chen

IPC: C08F20/56 ,  A61K31/785 ,  C09D5/16

CPC classification number: C09D5/1637 ,  A61K31/785 ,  B63B59/04 ,  C09D5/16 ,  C09D5/1606 ,  C09D5/165 ,  C09D5/1656 ,  C09D5/1662 ,  C09D5/1668 ,  C09D5/1675 ,  C09D133/26 ,  C09D151/085 ,  C09D153/00 ,  C09D183/04 ,  Y10T428/31511 ,  Y10T428/3154 ,  Y10T428/31551 ,  Y10T428/31663 ,  Y10T428/31725 ,  Y10T428/31786 ,  Y10T428/31844 ,  Y10T428/31938 ,  Y10T428/31942 ,  Y10T442/10

Abstract: Marine coatings including cationic polymers hydrolyzable to nonfouling zwitterionic polymers, coated marine surfaces, and methods for making and using the marine coatings.

Abstract translation: 海洋涂料包括可水解成非结垢的两性离子聚合物的阳离子聚合物，涂覆的海洋表面，以及用于制造和使用海洋涂料的方法。

公开(公告)号：US20150322189A1

公开(公告)日：2015-11-12

申请号：US14698721

申请日：2015-04-28

Applicant: University of Washington

Inventor： Shaoyi Jiang ,  Shengfu Chen

IPC: C08F220/10

CPC classification number: C08F220/10 ,  B29C39/20 ,  C08F220/26 ,  C08F220/34 ,  C08F222/1006 ,  C08L51/04

Abstract: Nonfouling copolymers and hydrogels comprising positively charged repeating units or latent positively charged repeating units and negatively charged units or latent positively charged units.

公开(公告)号：US10544312B2

公开(公告)日：2020-01-28

申请号：US15394538

申请日：2016-12-29

Applicant: University of Washington

Inventor： Shaoyi Jiang ,  Yuting Li ,  Hong Xue ,  Shengfu Chen

IPC: C08F20/56 ,  C09D5/16 ,  A61K31/785 ,  B63B59/04 ,  C09D133/26 ,  C09D151/08 ,  C09D153/00 ,  C09D183/04

Abstract: Marine coatings including cationic polymers hydrolyzable to nonfouling zwitterionic polymers, coated marine surfaces, and methods for making and using the marine coatings.

公开(公告)号：US10060918B2

公开(公告)日：2018-08-28

申请号：US15396128

申请日：2016-12-30

Applicant: University of Washington

Inventor： Shaoyi Jiang ,  Zheng Zhang ,  Shengfu Chen ,  Hana Vaisocherova

IPC: G01N33/545 ,  C08F122/22 ,  G01N33/543

CPC classification number: G01N33/545 ,  C08F122/22 ,  G01N33/54353

Abstract: Dual-functional nonfouling surfaces and materials, methods for making dual-functional nonfouling surfaces and materials, and devices that include dual-functional nonfouling surfaces and materials. The dual-functional surfaces are nonfouling surfaces that resist non-specific protein adsorption and cell adhesion. The dual-functional surfaces and materials include covalently coupled biomolecules (e.g., target binding partners) that impart specific biological activity thereto. The surfaces and materials are useful in medical diagnostics, biomaterials and bioprocessing, tissue engineering, and drug delivery.

公开(公告)号：US09598544B2

公开(公告)日：2017-03-21

申请号：US14184540

申请日：2014-02-19

Applicant: University of Washington

Inventor： Shaoyi Jiang ,  Shengfu Chen ,  Yung Chang ,  Zheng Zhang

IPC: C07C317/08 ,  C07C317/28 ,  C07C317/44 ,  C07C317/50 ,  A61K49/18 ,  C08J3/075 ,  C09D5/16 ,  C09D7/12 ,  C08F120/36 ,  C08F292/00 ,  B82Y30/00 ,  C08K3/16 ,  C08K3/34 ,  C08K9/08 ,  C08F220/36

CPC classification number: C08J3/075 ,  A61K49/18 ,  B82Y30/00 ,  C07C317/08 ,  C07C317/28 ,  C07C317/44 ,  C07C317/50 ,  C08F120/36 ,  C08F292/00 ,  C08F2220/365 ,  C08F2438/01 ,  C08K3/16 ,  C08K3/34 ,  C08K9/08 ,  C09D5/1637 ,  C09D7/62 ,  C09D7/67 ,  C09D7/68

Abstract: Nanoparticles zwitterionic polymers grafted thereto or grafted therefrom, and methods for making and using the nanoparticles. Zwitterionic nanogels, and methods for making and using the nanogels.

公开(公告)号：US20140370567A1

公开(公告)日：2014-12-18

申请号：US14470775

申请日：2014-08-27

Applicant: UNIVERSITY OF WASHINGTON

Inventor： Shaoyi Jiang ,  Zheng Zhang ,  Shengfu Chen ,  Hana Vaisocherova

IPC: G01N33/545 ,  C08F122/22

CPC classification number: G01N33/545 ,  C08F122/22 ,  G01N33/54353

Abstract: Dual-functional nonfouling surfaces and materials, methods for making dual-functional nonfouling surfaces and materials, and devices that include dual-functional nonfouling surfaces and materials. The dual-functional surfaces are nonfouling surfaces that resist non-specific protein adsorption and cell adhesion. The dual-functional surfaces and materials include covalently coupled biomolecules (e.g., target binding partners) that impart specific biological activity thereto. The surfaces and materials are useful in medical diagnostics, biomaterials and bioprocessing, tissue engineering, and drug delivery.

Abstract translation: 双功能非结垢表面和材料，用于制造双功能非结垢表面和材料的方法，以及包括双功能非结垢表面和材料的装置。 双功能表面是抵抗非特异性蛋白质吸附和细胞粘附的非结垢表面。 双功能表面和材料包括向其赋予特定生物活性的共价偶联的生物分子（例如靶结合配偶体）。 表面和材料可用于医学诊断，生物材料和生物处理，组织工程和药物递送。