公开(公告)号：US20110270092A1

公开(公告)日：2011-11-03

申请号：US13016642

申请日：2011-01-28

申请人： Uk KANG ,  Soo Jin Bae ,  Guang Hoon Kim ,  Seung Yup Lee ,  Garry V. Papayan

发明人： Uk KANG ,  Soo Jin Bae ,  Guang Hoon Kim ,  Seung Yup Lee ,  Garry V. Papayan

IPC分类号： A61B6/00 ,  A61N5/06

CPC分类号： A61B5/0071 ,  A61N5/062 ,  A61N2005/0628 ,  G01J3/2823 ,  G01J3/4406 ,  G01J2003/1213

摘要： The present invention provides a fluorescence detection and photodynamic therapy apparatus including: a combined light source unit 10 including a plurality of coherent and non-coherent light sources 11, 12 and 13 configured to irradiate light onto a to-be-observed object while performing continuous illumination; an optical imaging unit 20 configured to form an image of the to-be-observed object 70 and project the image to an image processing/controlling system 34; a multispectral imaging unit 30 including a one-chip multispectral sensor and the image processing/controlling system 34; a blocking filter 40 installed between the to-be-observed object 70 and the one-chip multispectral sensor 32, the blocking filter being configured to block some light reflected off from the to-be-observed object 70 while allowing some light and fluorescent light to pass therethrough; a computer system 50 configured to process, analyze, reproduce and store the image acquired from the multispectral imaging unit 30, and transfer the image to a display device 60 and control the overall operation of all the related elements; and the display device 60 configured to display a processing result of the image by the computer system 50.

摘要翻译： 本发明提供了一种荧光检测和光动力治疗装置，其包括：组合光源单元10，包括多个相干和非相干光源11,12和13，其被配置为将光照射到被观察物体上，同时执行连续 照明; 光学成像单元20，被配置为形成待观察对象70的图像，并将图像投影到图像处理/控制系统34; 包括单芯片多光谱传感器和图像处理/控制系统34的多光谱成像单元30; 安装在被观察物体70和单芯片多光谱传感器32之间的阻挡滤光器40，阻挡滤光器被配置为阻挡从被观察物体70反射的一些光，同时允许一些光和荧光灯 通过; 被配置为处理，分析，再现和存储从多光谱成像单元30获取的图像的计算机系统50，并将图像传送到显示设备60并控制所有相关元件的整体操作; 并且显示装置60被配置为通过计算机系统50显示图像的处理结果。

公开(公告)号：US08647372B2

公开(公告)日：2014-02-11

申请号：US12168351

申请日：2008-07-07

申请人： Uk Kang ,  Soo Jin Bae ,  Seung Yup Lee ,  Guang Hoon Kim ,  Geun Hee Rim ,  Geri. V Papyan ,  Dmitry Makarov

发明人： Uk Kang ,  Soo Jin Bae ,  Seung Yup Lee ,  Guang Hoon Kim ,  Geun Hee Rim ,  Geri. V Papyan ,  Dmitry Makarov

IPC分类号： A61N5/06

CPC分类号： A61N5/0616 ,  A61B2018/207 ,  A61N2005/063 ,  A61N2005/0659 ,  A61N2005/0661

摘要： The present invention provides a composite light source apparatus for phototherapy of skin disease, in which a light beam having the wavelength and optical power suitable for light-beam treatment is provided to a region to be treated (also called a ‘to-be-treated region’) through a light guide by using a composite light source so as to improve efficiency of phototherapy of skin diseases of the body including acne, malignant tumors and the like. According to the composite light source apparatus, uniform optical power can be provided through a combination of a plurality of light sources, the optical power can be provided through selection of light of a wavelength range that a user wants, and light from the light sources can be utilized to the maximum with increased light intensity.

摘要翻译： 本发明提供了一种用于皮肤病光疗的复合光源装置，其中具有适用于光束处理的波长和光焦度的光束被提供给待治疗的区域（也称为待治疗的区域 区域'）通过使用复合光源通过光导，以提高身体皮肤疾病（包括痤疮，恶性肿瘤等）的光疗效率。 根据复合光源装置，可以通过多个光源的组合来提供均匀的光功率，可以通过选择用户想要的波长范围的光来提供光功率，并且来自光源的光可以 最大限度地利用增加的光强度。

公开(公告)号：US20090093866A1

公开(公告)日：2009-04-09

申请号：US12168351

申请日：2008-07-07

申请人： Uk Kang ,  Soo Jin Bae ,  Seung Yup Lee ,  Guang Hoon Kim ,  Geun Hee Rim ,  Geri V. Papayan ,  Dmitry Makarov

发明人： Uk Kang ,  Soo Jin Bae ,  Seung Yup Lee ,  Guang Hoon Kim ,  Geun Hee Rim ,  Geri V. Papayan ,  Dmitry Makarov

IPC分类号： A61N5/06

CPC分类号： A61N5/0616 ,  A61B2018/207 ,  A61N2005/063 ,  A61N2005/0659 ,  A61N2005/0661

摘要： The present invention provides a composite light source apparatus for phototherapy of skin disease, in which a light beam having the wavelength and optical power suitable for light-beam treatment is provided to a region to be treated (also called a ‘to-be-treated region’) through a light guide by using a composite light source so as to improve efficiency of phototherapy of skin diseases of the body including acne, malignant tumors and the like. According to the composite light source apparatus, uniform optical power can be provided through a combination of a plurality of light sources, the optical power can be provided through selection of light of a wavelength range that a user wants, and light from the light sources can be utilized to the maximum with increased light intensity.

摘要翻译： 本发明提供了一种用于皮肤病光疗的复合光源装置，其中具有适用于光束处理的波长和光焦度的光束被提供给待治疗的区域（也称为待治疗的区域 区域'）通过使用复合光源通过光导，以提高身体皮肤疾病（包括痤疮，恶性肿瘤等）的光疗效率。 根据复合光源装置，可以通过多个光源的组合来提供均匀的光功率，可以通过选择用户想要的波长范围的光来提供光功率，并且来自光源的光可以 最大限度地利用增加的光强度。

公开(公告)号：US08162496B2

公开(公告)日：2012-04-24

申请号：US11811677

申请日：2007-06-11

申请人： Uk Kang ,  Soo Jin Bae ,  Geun Hie Rim ,  Guang Hoon Kim ,  Geri. V Papayan

发明人： Uk Kang ,  Soo Jin Bae ,  Geun Hie Rim ,  Guang Hoon Kim ,  Geri. V Papayan

IPC分类号： G03B15/02

CPC分类号： G01N21/6486 ,  A61B5/0059 ,  A61B5/0071 ,  A61B5/441

摘要： The present invention provides an apparatus for white light observation and fluorescence diagnosis of skin diseases. More particularly, the present invention provides an apparatus for photodynamic diagnosis in which a plurality of excitation light emitting diodes (LEDs) is provided in an image pick-up head, the excitation LEDs being arranged to illuminate the entire examination region in the form of a mosaic by setting respective illumination light axes of the excitation LEDs to illuminate preassigned individual areas of the examination region, thus uniformly illuminating the examination region in a wide field of view with excitation light. In the apparatus for photodynamic diagnosis, the respective excitation LEDs are provided at the same or different angles based on the light axis of the object lens, and thereby it is possible that the beams of the light sources composed of the LEDs illuminate the field of view of the examination region uniformly, thus improving the uniformity of illumination. Moreover, the present invention provides an apparatus for photodynamic diagnosis in which warm white LEDs and cold white LEDs as white light sources are appropriately arranged so as to deliver natural colors and thereby to reproduce natural color images.

摘要翻译： 本发明提供了一种用于白光观察和皮肤疾病荧光诊断的装置。 更具体地说，本发明提供了一种用于光动力学诊断的装置，其中多个激发发光二极管（LED）被提供在图像拾取头中，激发LED被布置成以整体形式照射整个检查区域 通过设置激发LED的各个照明光轴来照亮检查区域的预分配的各个区域，从而在激发光的宽视场内均匀地照射检查区域。 在光动力诊断装置中，基于物镜的光轴以相同或不同的角度设置各激发LED，由此，由LED组成的光源的光束可以照射视场 的检查区域均匀，从而提高了照明的均匀性。 此外，本发明提供了一种用于光动力诊断的装置，其中温白色LED和作为白光源的冷白光LED被适当地布置以便传送自然色，从而再现自然色图像。

公开(公告)号：US08496695B2

公开(公告)日：2013-07-30

申请号：US11811912

申请日：2007-06-11

申请人： Uk Kang ,  Soo Jin Bae ,  Geun Hie Rim ,  Guang Hoon Kim ,  Geri V. Papayan

发明人： Uk Kang ,  Soo Jin Bae ,  Geun Hie Rim ,  Guang Hoon Kim ,  Geri V. Papayan

IPC分类号： A61N5/06

CPC分类号： A61N5/062 ,  A61B5/0071 ,  A61B5/441 ,  A61B2017/00057 ,  A61B2017/00747 ,  A61B2090/373 ,  A61N5/0616 ,  G01N21/6456 ,  G01N21/6486

摘要： A system is provided for photodynamic diagnosis and therapy of skin diseases. In particular, a camera head is provided to irradiate a white light, a fluorescent excitation light and a therapeutic light for the photodynamic therapy from the inside of a case onto the skin region being in contact with a view hole. Additionally, a digital color TV camera collects the light from the skin region and outputs a generated image signal. In particular, an image processing and analysis system receives the image signals from the camera head to process, analyze and store the same, displays a color image by the white light, a fluorescent image by the excitation light and the therapeutic light for the photodynamic therapy, obtained by the digital color TV camera, and a synthesized image thereof, and controls the general operations of the camera and the light source system.

摘要翻译： 提供一种用于光动力诊断和治疗皮肤疾病的系统。 特别地，提供一种照相机头，用于将来自外壳内部的光动力学治疗的白光，荧光激发光和治疗光照射到与观察孔接触的皮肤区域上。 此外，数字彩色电视摄像机收集来自皮肤区域的光并输出生成的图像信号。 特别地，图像处理和分析系统接收来自相机头的图像信号以进行处理，分析和存储，通过白光显示彩色图像，通过激发光显示荧光图像和用于光动力学治疗的治疗光 ，由数字彩色电视摄像机获得，并且其合成图像，并且控制照相机和光源系统的一般操作。

公开(公告)号：US20080180950A1

公开(公告)日：2008-07-31

申请号：US11811677

申请日：2007-06-11

申请人： Uk Kang ,  Soo Jin Bae ,  Geun Hie Rim ,  Guang Hoon Kim ,  Geri V. Papayan

发明人： Uk Kang ,  Soo Jin Bae ,  Geun Hie Rim ,  Guang Hoon Kim ,  Geri V. Papayan

IPC分类号： F21S13/14

CPC分类号： G01N21/6486 ,  A61B5/0059 ,  A61B5/0071 ,  A61B5/441

摘要： The present invention provides an apparatus for white light observation and fluorescence diagnosis of skin diseases. More particularly, the present invention provides an apparatus for photodynamic diagnosis in which a plurality of excitation light emitting diodes (LEDs) is provided in an image pick-up head, the excitation LEDs being arranged to illuminate the entire examination region in the form of a mosaic by setting respective illumination light axes of the excitation LEDs to illuminate preassigned individual areas of the examination region, thus uniformly illuminating the examination region in a wide field of view with excitation light. In the apparatus for photodynamic diagnosis, the respective excitation LEDs are provided at the same or different angles based on the light axis of the object lens, and thereby it is possible that the beams of the light sources composed of the LEDs illuminate the field of view of the examination region uniformly, thus improving the uniformity of illumination. Moreover, the present invention provides an apparatus for photodynamic diagnosis in which warm white LEDs and cold white LEDs as white light sources are appropriately arranged so as to deliver natural colors and thereby to reproduce natural color images.

摘要翻译： 本发明提供了一种用于白光观察和皮肤疾病的荧光诊断的装置。 更具体地说，本发明提供了一种用于光动力学诊断的装置，其中多个激发发光二极管（LED）被提供在图像拾取头中，激发LED被布置成以整体形式照射整个检查区域 通过设置激发LED的各个照明光轴来照亮检查区域的预分配的各个区域，从而在激发光的宽视场内均匀地照射检查区域。 在光动力诊断装置中，基于物镜的光轴以相同或不同的角度设置各激发LED，由此，由LED组成的光源的光束可以照射视场 的检查区域均匀，从而提高了照明的均匀性。 此外，本发明提供了一种用于光动力诊断的装置，其中温白色LED和作为白光源的冷白光LED被适当地布置以便传送自然色，从而再现自然色图像。

公开(公告)号：US20080147053A1

公开(公告)日：2008-06-19

申请号：US11811912

申请日：2007-06-11

申请人： Uk Kang ,  Soo Jin Bae ,  Geun Hie Rim ,  Guang Hoon Kim ,  Geri V. Papayan

发明人： Uk Kang ,  Soo Jin Bae ,  Geun Hie Rim ,  Guang Hoon Kim ,  Geri V. Papayan

IPC分类号： A61B18/18

CPC分类号： A61N5/062 ,  A61B5/0071 ,  A61B5/441 ,  A61B2017/00057 ,  A61B2017/00747 ,  A61B2090/373 ,  A61N5/0616 ,  G01N21/6456 ,  G01N21/6486

摘要： The present invention provides an apparatus and method for photodynamic diagnosis and therapy of skin diseases and a light source system thereof that can improve the efficiency of skin diagnosis by accurately analyzing skin conditions using fluorescence and white light simultaneously and further carry out fluorescent diagnosis and photodynamic therapy in the same skin region simultaneously. The apparatus for photodynamic diagnosis and therapy of skin diseases of the present invention includes: a camera head including a case having a view hole, provided in front thereof, to be in contact with a skin region, a white light source provided so as to irradiate a white light from the inside of the case through the view hole onto the skin region, a digital color TV camera provided in the rear of the case, the camera head being provided to irradiate the white light, a fluorescence excitation light and a therapeutic light for the photodynamic therapy from the inside of the case onto the skin region being in contact with the view hole, and the digital color TV camera collecting the light from the skin region and outputting a generated image signal; a light source system, connected to the case of the camera head through a light guide capable of light transmission, for providing the fluorescence excitation light, the therapeutic light for the photodynamic therapy and the white light to be irradiated onto the skin region to the camera head; and an image processing and analysis system for receiving the image signal from the camera head to process, analyze and store to same, for displaying a color image by the white light, a fluorescence image by the excitation light and the therapeutic light for the photodynamic therapy, obtained by the digital color TV camera, and a synthesized image thereof, and for controlling the general operations of the camera head and the light source system.

公开(公告)号：US08582613B1

公开(公告)日：2013-11-12

申请号：US13563434

申请日：2012-07-31

申请人： Guang Hoon Kim ,  Uk Kang ,  Ju Hee Yang ,  Dae Sik Lee ,  Elena Sall ,  Sergey Chizhov ,  Andrey Kulik ,  Vladimir Yashin

发明人： Guang Hoon Kim ,  Uk Kang ,  Ju Hee Yang ,  Dae Sik Lee ,  Elena Sall ,  Sergey Chizhov ,  Andrey Kulik ,  Vladimir Yashin

IPC分类号： H01S3/10

CPC分类号： H01S3/1675 ,  H01S3/0057 ,  H01S3/0401 ,  H01S3/07 ,  H01S3/0805 ,  H01S3/08054 ,  H01S3/08072 ,  H01S3/09415 ,  H01S3/1618 ,  H01S3/235

摘要： Disclosed is a laser apparatus of amplifying a laser pulse output using an anisotropic laser crystal through chirped pulse amplification. The laser apparatus includes a laser resonator. The laser resonator includes a plurality of anisotropic laser crystals, generates a shorter femtosecond pulse by widening a spectrum bandwidth through a combination of different gain spectrum distributions using the anisotropic laser crystals, and allows a laser beam to travel in axial directions with different thermal characteristics of the anisotropic layer crystals in order to reduce a thermal effect.

摘要翻译： 公开了一种使用各向异性激光晶体通过啁啾脉冲放大来放大激光脉冲输出的激光装置。 激光装置包括激光谐振器。 激光谐振器包括多个各向异性激光晶体，通过使用各向异性激光晶体的不同增益谱分布的组合扩大频谱带宽来产生较短的飞秒脉冲，并允许激光束沿轴向行进，具有不同的热特性 各向异性层晶体为了降低热效应。

公开(公告)号：US20130051411A1

公开(公告)日：2013-02-28

申请号：US13562045

申请日：2012-07-30

申请人： Guang Hoon Kim ,  Uk Kang ,  Ju Hee Yang ,  Elena Sall ,  Sergey Chizhov ,  Andrey Kulik

发明人： Guang Hoon Kim ,  Uk Kang ,  Ju Hee Yang ,  Elena Sall ,  Sergey Chizhov ,  Andrey Kulik

IPC分类号： H01S3/098

CPC分类号： H01S3/09415 ,  H01S3/025 ,  H01S3/08059 ,  H01S3/0811 ,  H01S3/1118 ,  H01S5/02415

摘要： The present invention provides a femtosecond laser apparatus using laser diode optical pumping. To provide a stable mode locking and improve power stability and beam stability in an ultrafast laser such as a femtosecond laser, optical mounts which have mounted thereon optical parts of a diode pumping unit are mechanically engaged using bars of low thermal expansion coefficients and form a pumping module, and the pumping module is maximally separated from a laser platform or case.

摘要翻译： 本发明提供一种使用激光二极管光泵浦的飞秒激光装置。 为了提供稳定的模式锁定并且在诸如飞秒激光器的超快激光器中提高功率稳定性和光束稳定性，其上安装有二极管泵浦单元的光学部件的光学安装座使用低热膨胀系数的棒来机械地接合并形成泵 模块，并且泵送模块与激光平台或壳体最大程度地分离。

公开(公告)号：US20100121418A1

公开(公告)日：2010-05-13

申请号：US12474522

申请日：2009-05-29

申请人： Dae Sic LEE ,  Guang Hoon Kim ,  Uk Kang ,  R. Andreev

发明人： Dae Sic LEE ,  Guang Hoon Kim ,  Uk Kang ,  R. Andreev

IPC分类号： A61N5/067 ,  A61F7/00

CPC分类号： A61B18/203 ,  A61B2018/00029 ,  A61B2018/00452 ,  A61N5/0616

摘要： The present invention provides a skin cooling system which can improve skin cooling efficiency and significantly reduce thermal damage and pain caused by heat generated during treatment, using a handpiece for injecting cold air, water, or a mixture of cold air and water.For this purpose, the present invention provides a skin cooling system including: a handpiece for focusing therapeutic light energy onto the surface of the skin for treatment and injecting cold air, water, or a mixture of cold air and water to the skin during treatment; a cold air supply means connected to the handpiece to supply cold air; and a cold water supply means connected to the handpiece to supply cooling water.

摘要翻译： 本发明提供了一种皮肤冷却系统，其可以使用用于注射冷空气，水或冷空气和水的混合物的手持件来改善皮肤冷却效率并显着减少由治疗期间产生的热引起的热损伤和疼痛。 为此目的，本发明提供了一种皮肤冷却系统，包括：用于将治疗光能聚焦到皮肤表面上的手持件，用于在治疗期间将冷空气，水或冷空气和水的混合物注入皮肤; 连接到所述手持件以供应冷空气的冷气供应装置; 以及连接到所述手持件以供应冷却水的冷水供应装置。