公开(公告)号：US09005270B2

公开(公告)日：2015-04-14

申请号：US13430942

申请日：2012-03-27

Applicant: Keith Perkins ,  Samuel Robaina ,  Jeffery Argentine ,  Walter Bruszewski ,  Andrew Kiehl

Inventor： Keith Perkins ,  Samuel Robaina ,  Jeffery Argentine ,  Walter Bruszewski ,  Andrew Kiehl

IPC: A61F2/82 ,  A61F2/915

CPC classification number: A61F2/915 ,  A61F2002/91525

Abstract: A method includes covering ostai of branch vessels emanating from a main vessel and an aneurysm with a high metal to vessel ratio stent. A metal to vessel ratio of the high metal to vessel ratio stent is sufficiently high to encourage tissue ingrowth around the high metal to vessel ratio stent yet is sufficiently low to ensure perfusion of the branch vessels through the high metal to vessel ratio stent. The ingrowth of tissue provides secure fixation and sealing of the high metal to vessel ratio stent to the main vessel and remodels and essentially eliminates the aneurysm. Further, as the entire high metal to vessel ratio stent is permeably, the high metal to vessel ratio stent is deployed without having to rotationally position the high metal to vessel ratio stent.

Abstract translation: 一种方法包括覆盖从主血管发出的分支血管和具有高金属与血管比例支架的动脉瘤。 高金属与血管比支架的金属与血管比例足够高以促使组织向内生长高金属与血管比例支架，但足够低以确保分支血管通过高金属与血管比例的支架灌注。 组织的向内生长提供了高金属与血管比例支架到主血管的牢固固定和密封，并且改造并且基本上消除了动脉瘤。 此外，随着整个高金属与血管比例的支架是可渗透的，高金属与血管比例的支架被展开，而不必旋转地定位高金属与血管比例的支架。

公开(公告)号：US08506622B2

公开(公告)日：2013-08-13

申请号：US12425628

申请日：2009-04-17

Applicant: Walter Bruszewski ,  Kevin Boyle ,  Masoumeh Mafi

Inventor： Walter Bruszewski ,  Kevin Boyle ,  Masoumeh Mafi

IPC: A61F2/06

CPC classification number: A61F2/07 ,  A61F2/88 ,  A61F2/89 ,  A61F2/954 ,  A61F2002/061 ,  A61F2002/075 ,  A61F2002/30125 ,  A61F2002/30327 ,  A61F2002/30604 ,  A61F2002/9665 ,  A61F2230/0008 ,  A61F2250/0039 ,  A61F2250/006

Abstract: An endovascular prosthesis includes a tubular body and a flexible springy mobile external coupling. The tubular body includes a graft material and stents coupled thereto with a forms a lumen therethrough. The mobile external coupling extends outwardly from the tubular body. The mobile external coupling includes a graft material and is generally frustoconically shaped. The mobile external coupling includes a base coupled to the tubular body, a top spaced from the tubular body, and a coupling lumen disposed between the base and the top, wherein the coupling lumen is in flow communication with the body lumen. A helically shaped stent may be coupled to the coupling graft material to make it flexible and springy.

Abstract translation: 血管内假体包括管状主体和柔性弹性移动外部联接器。 管状体包括移植材料和与其结合的支架，其形成通过其中的腔。 移动外部联接件从管状体向外延伸。 移动外部联接件包括移植材料并且通常是截头圆锥形的。 移动外部联接器包括联接到管状体的基部，与管状体间隔开的顶部以及设置在基部和顶部之间的联接腔，其中联接腔与体腔流动连通。 螺旋形支架可以联接到联接移植物材料，以使其柔性和弹性。

公开(公告)号：US08473030B2

公开(公告)日：2013-06-25

申请号：US11622935

申请日：2007-01-12

Applicant: Trevor Greenan ,  Dwayne Yamasaki ,  Walter Bruszewski ,  Ken Gardeski ,  David Simon

Inventor： Trevor Greenan ,  Dwayne Yamasaki ,  Walter Bruszewski ,  Ken Gardeski ,  David Simon

IPC: A61B5/055

CPC classification number: A61B5/06 ,  A61B5/062 ,  A61B5/6857 ,  A61B34/20 ,  A61B90/36 ,  A61B2017/003 ,  A61B2017/00867 ,  A61B2034/105 ,  A61B2034/107 ,  A61B2034/2051 ,  A61B2562/0209 ,  A61B2562/043 ,  A61F2/07 ,  A61F2/954 ,  A61F2002/061 ,  A61F2002/065 ,  A61F2250/0002 ,  A61F2250/0096 ,  A61M25/007 ,  A61M25/0108 ,  A61M2025/0166

Abstract: One or more markers or sensors are positioned in the vasculature of a patient to facilitate determining the location, configuration, and/or orientation of a vessel or certain aspects thereof (e.g., a branch vessel), determining the location, configuration and/or orientation of a endovascular devices prior to and during prosthesis deployment as well as the relative position of portions of the vasculature and devices, generating an image of a virtual model of a portion of one or more vessels (e.g., branch vessels) or devices, and/or formation of one or more openings in a tubular prosthesis in situ to allow branch vessel perfusion when the prosthesis is placed over one or more branch vessels in a patient (e.g., when an aortic abdominal artery stent-graft is fixed to the aorta superior to the renal artery ostia).

Abstract translation: 一个或多个标记或传感器被定位在患者的脉管系统中以便于确定血管的位置，构型和/或取向或其某些方面（例如，分支血管），确定位置，构型和/或取向 在假体部署之前和期间的血管内装置以及脉管系统和装置的部分的相对位置，产生一个或多个血管（例如，分支血管）或装置的一部分的虚拟模型的图像，和/ 或在管状假体中原位形成一个或多个开口，以便当假体放置在患者的一个或多个分支血管上时（例如，当主动脉腹膜动脉支架移植物被固定到主动脉上方时，分支血管灌注 肾动脉口）。

公开(公告)号：US20120271401A1

公开(公告)日：2012-10-25

申请号：US13089545

申请日：2011-04-19

Applicant: Walter Bruszewski ,  Malhar Desai

Inventor： Walter Bruszewski ,  Malhar Desai

IPC: A61F2/82

CPC classification number: A61F2/954 ,  A61F2/07 ,  A61F2/89 ,  A61F2/90 ,  A61F2/966 ,  A61F2002/061 ,  A61F2002/075 ,  A61F2002/9505 ,  A61F2002/9517 ,  A61F2002/9665 ,  A61F2220/0075

Abstract: An endovascular prosthesis includes a tubular body and a mobile external coupling. The tubular body includes a graft material and stents coupled thereto, and forms a lumen therethrough. The mobile external coupling includes a graft material, extends outwardly from the tubular body, and is generally frustoconically shaped. The mobile external coupling includes a base coupled to the tubular body, a top spaced from the tubular body, and a coupling lumen disposed between the base and the top that is in flow communication with the body lumen. An annular support wireform is coupled to the mobile external coupling, and is formed into a sinusoidal configuration having a plurality of opposing first crowns and second crowns, the first crowns of the support wireform extending around of the top of the mobile external coupling. The coupling graft material extending between the second crowns of the support wireform and the tubular body is unsupported.

Abstract translation: 血管内假体包括管状主体和移动外部联接器。 管状体包括移植材料和与其连接的支架，并且形成通过其中的内腔。 移动外部联接器包括从管状体向外延伸的移植材料，并且通常为截头圆锥形状。 移动外部联接器包括联接到管状体的基部，与管状体间隔开的顶部，以及设置在基部和顶部之间的与体腔流动连通的联接腔。 环形支撑线形联接到移动外部联接器，并且形成为具有多个相对的第一冠部和第二冠部的正弦构造，支撑线形模的第一冠部围绕可移动外部联接器的顶部延伸。 在支撑线形的第二冠和管状体之间延伸的联接移植物材料是不受支撑的。

公开(公告)号：US20120271236A1

公开(公告)日：2012-10-25

申请号：US13089592

申请日：2011-04-19

Applicant: Walter Bruszewski

Inventor： Walter Bruszewski

IPC: A61B17/34 ,  A61M39/06

CPC classification number: A61M39/0613 ,  A61M39/0606 ,  A61M2039/0633 ,  A61M2039/0673 ,  A61M2039/0686

Abstract: A sheath introducer system with exchangeable hemostatic valve modules is disclosed. A first valve module includes a single entry port to ensure hemostasis during the introduction of an interventional device, such as a main graft delivery system for treatment of an abdominal aortic aneurysm (AAA). A second valve module includes multiple entry ports to ensure hemostasis during the simultaneous introduction and manipulation of multiple interventional devices, such as multiple guiding catheters for use in delivering various intravascular graft components for completion of branch perfusion, for instance, during treatment of the AAA.

Abstract translation: 公开了一种具有可更换止血阀模块的护套导引器系统。 第一阀模块包括单个进入口，以在引入介入装置期间确保止血，例如用于治疗腹主动脉瘤（AAA）的主移植物递送系统。 第二阀模块包括多个输入端口，以在同时引入和操纵多个介入装置期间确保止血，例如用于递送各种血管内移植物组分以完成分支灌注的多个引导导管，例如在治疗AAA期间。

公开(公告)号：US08142493B2

公开(公告)日：2012-03-27

申请号：US12177554

申请日：2008-07-22

Applicant: Paul A. Spence ,  Walter Bruszewski ,  Ed McNamara ,  Mark Maguire

Inventor： Paul A. Spence ,  Walter Bruszewski ,  Ed McNamara ,  Mark Maguire

IPC: A61F2/24

CPC classification number: A61F2/2466 ,  A61B17/0401 ,  A61B17/0469 ,  A61B17/0482 ,  A61B17/0487 ,  A61B17/064 ,  A61B2017/00398 ,  A61B2017/00862 ,  A61B2017/00867 ,  A61B2017/00876 ,  A61B2017/0406 ,  A61B2017/0409 ,  A61B2017/0417 ,  A61B2017/0419 ,  A61B2017/0454 ,  A61B2017/0458 ,  A61B2017/0464 ,  A61B2017/0496 ,  A61B2017/0641 ,  A61B2017/0647 ,  A61F2/2445 ,  A61F2/2451 ,  Y10S623/904

Abstract: Catheter based systems and methods for securing tissue including the annulus of a mitral valve. The systems and methods employ catheter based techniques and devices to plicate tissue and perform an annuloplasty.

Abstract translation: 基于导管的系统和用于固定包括二尖瓣环的组织的方法。 该系统和方法采用基于导管的技术和装置来剔除组织并执行瓣环成形术。

公开(公告)号：US09839542B2

公开(公告)日：2017-12-12

申请号：US13089545

申请日：2011-04-19

Applicant: Walter Bruszewski ,  Malhar Desai

Inventor： Walter Bruszewski ,  Malhar Desai

IPC: A61F2/06 ,  A61F2/954 ,  A61F2/07 ,  A61F2/966 ,  A61F2/95 ,  A61F2/89 ,  A61F2/90

CPC classification number: A61F2/954 ,  A61F2/07 ,  A61F2/89 ,  A61F2/90 ,  A61F2/966 ,  A61F2002/061 ,  A61F2002/075 ,  A61F2002/9505 ,  A61F2002/9517 ,  A61F2002/9665 ,  A61F2220/0075

Abstract: An endovascular prosthesis includes a tubular body and a mobile external coupling. The tubular body includes a graft material and stents coupled thereto, and forms a lumen therethrough. The mobile external coupling includes a graft material, extends outwardly from the tubular body, and is generally frustoconically shaped. The mobile external coupling includes a base coupled to the tubular body, a top spaced from the tubular body, and a coupling lumen disposed between the base and the top that is in flow communication with the body lumen. An annular support wireform is coupled to the mobile external coupling, and is formed into a sinusoidal configuration having a plurality of opposing first crowns and second crowns, the first crowns of the support wireform extending around of the top of the mobile external coupling. The coupling graft material extending between the second crowns of the support wireform and the tubular body is unsupported.

公开(公告)号：US20130261732A1

公开(公告)日：2013-10-03

申请号：US13431732

申请日：2012-03-27

Applicant: Kieth Perkins ,  Samuel Robaina ,  Jeffery Argentine ,  Walter Bruszewski ,  Andrew Kiehl

Inventor： Kieth Perkins ,  Samuel Robaina ,  Jeffery Argentine ,  Walter Bruszewski ,  Andrew Kiehl

IPC: A61F2/82 ,  C23F1/02 ,  B23K26/00

CPC classification number: A61F2/07 ,  A61F2/915 ,  A61F2002/061 ,  A61F2240/001

Abstract: A method includes covering ostai of branch vessels emanating from a main vessel and an aneurysm with an integrated mesh high metal to vessel ratio stent. The integrated mesh high metal to vessel ratio stent includes serpentine rings integrated with an integrated mesh having holes formed therein. A metal to vessel ratio of the integrated mesh high metal to vessel ratio stent is sufficiently high to encourage tissue ingrowth around the integrated mesh high metal to vessel ratio stent yet is sufficiently low to ensure perfusion of the branch vessels through the integrated mesh high metal to vessel ratio stent.

Abstract translation: 一种方法包括覆盖从主血管发出的分支血管和具有整合的网状高金属比血管支架的动脉瘤。 集成网格高金属与容器比例支架包括与其中形成有孔的整体网格集成的蛇形环。 一体化网状高金属与血管比例支架的金属与血管比例足够高，以促进组合网格高金属与血管比支架之间的组织向内生长，但足够低以确保分支血管通过整体网格高金属的灌注至 血管比例支架。

公开(公告)号：US08337546B2

公开(公告)日：2012-12-25

申请号：US12770566

申请日：2010-04-29

Applicant: Walter Bruszewski

Inventor： Walter Bruszewski

IPC: A61F2/06

CPC classification number: A61F2/07 ,  A61F2/89 ,  A61F2002/061 ,  A61F2002/075 ,  A61F2002/821 ,  A61F2220/005 ,  A61F2220/0058 ,  A61F2220/0075

Abstract: An endovascular prosthesis includes a tubular body and a mobile external coupling. The tubular body includes a graft material and stents coupled thereto which forms a lumen therethrough. The mobile external coupling extends outwardly from the tubular body. The mobile external coupling includes a graft material and is generally frustoconically shaped. The mobile external coupling includes a base coupled to the tubular body, a top spaced from the tubular body, and a coupling lumen disposed between the base and the top, wherein the coupling lumen is in flow communication with the body lumen. A coupling deployment device is coupled to the coupling graft material to provide an extension force to extend the mobile external coupling from a collapsed configuration against the tubular body to an extended position wherein the mobile external coupling extends from the tubular body.

Abstract translation: 血管内假体包括管状主体和移动外部联接器。 管状体包括移植材料和与其结合的支架，其形成通过其中的腔。 移动外部联接器从管状体向外延伸。 移动外部联接件包括移植材料并且通常是截头圆锥形的。 移动外部联接器包括联接到管状体的基部，与管状体间隔开的顶部以及设置在基部和顶部之间的联接腔，其中联接腔与体腔流动连通。 耦合部署装置联接到联接移植材料以提供延伸力，以将可移动外部联接器从折叠构型延伸到管状主体到延伸位置，其中可移动外部联接件从管状体延伸。

公开(公告)号：US08333800B2

公开(公告)日：2012-12-18

申请号：US12770536

申请日：2010-04-29

Applicant: Walter Bruszewski ,  Heath Muzslay ,  Emilie Johnson ,  Kevin Boyle ,  Mohammed Iftekhar ,  Samuel Robaina

Inventor： Walter Bruszewski ,  Heath Muzslay ,  Emilie Johnson ,  Kevin Boyle ,  Mohammed Iftekhar ,  Samuel Robaina

IPC: A61F2/06

CPC classification number: A61F2/07 ,  A61F2/89 ,  A61F2002/061 ,  A61F2002/075 ,  A61F2220/005 ,  A61F2220/0058 ,  A61F2220/0075 ,  A61F2250/006

Abstract: An endovascular prosthesis includes a tubular body and a mobile external coupling. The tubular body includes a graft material and stents coupled thereto, a forms a lumen therethrough. The mobile external coupling extends outwardly from the tubular body. The mobile external coupling includes a graft material and is generally frustoconically shaped. The mobile external coupling includes a base coupled to the tubular body, a top spaced from the tubular body, and a coupling lumen disposed between the base and the top, wherein the coupling lumen is in flow communication with the body lumen. A cylindrical sealing cuff of graft material is attached to and extends from the top of the mobile external coupling towards the tubular body within the coupling lumen. The sealing cuff is configured to contact a portion of a branch vessel prosthesis and thereby provides an elongated interference seal between the branch vessel prosthesis and the mobile external coupling.

Abstract translation: 血管内假体包括管状主体和移动外部联接器。 管状体包括移植材料和与其连接的支架，a形成通过其中的腔。 移动外部联接件从管状体向外延伸。 移动外部联接件包括移植材料并且通常是截头圆锥形的。 移动外部联接器包括联接到管状体的基部，与管状体间隔开的顶部以及设置在基部和顶部之间的联接腔，其中联接腔与体腔流动连通。 移植材料的圆柱形密封套连接到移动外部联接器的顶部并且在联接腔内朝向管状体延伸。 密封套构造成接触分支血管假体的一部分，从而在分支血管假体和移动外部联接器之间提供细长的干涉密封。