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公开(公告)号:US09089523B2
公开(公告)日:2015-07-28
申请号:US13560362
申请日:2012-07-27
申请人: Hui Xu , Wenquan Sun , Hua Wan , Rick Owens
发明人: Hui Xu , Wenquan Sun , Hua Wan , Rick Owens
IPC分类号: A61K35/12 , A61K31/728 , A61K33/38 , A61K35/407 , A61K35/42 , A61K45/06 , A61K38/17 , A61K38/18 , A61L27/20 , A61L27/36 , A61L27/54 , C08L5/08
CPC分类号: A61L27/3604 , A61K31/728 , A61K38/1709 , A61K38/18 , A61L27/20 , A61L27/227 , A61L27/34 , A61L27/3683 , A61L27/54 , A61L2300/104 , A61L2300/206 , A61L2300/236 , A61L2300/252 , A61L2300/41 , C08L5/08 , A61K2300/00
摘要: Tissue fillers derived from decellularized tissues are provided. The tissue fillers can include acellular tissue matrices that have reduced inflammatory responses when implanted in a body. Also provided are methods of making and therapeutic uses for the tissue fillers.
摘要翻译: 提供衍生自脱细胞组织的组织填充物。 组织填充剂可以包括当植入体内具有降低的炎症反应的无细胞组织基质。 还提供了用于组织填充剂的制备和治疗用途的方法。
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公开(公告)号:US20130028984A1
公开(公告)日:2013-01-31
申请号:US13560362
申请日:2012-07-27
申请人: Hui Xu , Wenquan Sun , Hua Wan , Rick Owens
发明人: Hui Xu , Wenquan Sun , Hua Wan , Rick Owens
CPC分类号: A61L27/3604 , A61K31/728 , A61K38/1709 , A61K38/18 , A61L27/20 , A61L27/227 , A61L27/34 , A61L27/3683 , A61L27/54 , A61L2300/104 , A61L2300/206 , A61L2300/236 , A61L2300/252 , A61L2300/41 , C08L5/08 , A61K2300/00
摘要: Tissue fillers derived from decellularized tissues are provided. The tissue fillers can include acellular tissue matrices that have reduced inflammatory responses when implanted in a body. Also provided are methods of making and therapeutic uses for the tissue fillers.
摘要翻译: 提供衍生自脱细胞组织的组织填充物。 组织填充剂可以包括当植入体内具有降低的炎症反应的无细胞组织基质。 还提供了用于组织填充剂的制备和治疗用途的方法。
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公开(公告)号:US08637067B1
公开(公告)日:2014-01-28
申请号:US13415355
申请日:2012-03-08
申请人: Wenquan Sun , Hui Xu , Hua Wan
发明人: Wenquan Sun , Hui Xu , Hua Wan
CPC分类号: A61K35/44 , A61L26/0047 , A61L26/0057 , A61L26/0066 , A61L26/008 , A61L26/0095 , A61L27/3625 , A61L27/3683 , A61L27/3687 , A61L27/52 , A61L27/54 , A61L2300/404 , A61L2300/414 , A61L2300/416 , A61L2430/34
摘要: A tissue-derived hydrogel, as well as methods of making and using such hydrogels, are provided.
摘要翻译: 提供组织衍生的水凝胶,以及制备和使用这种水凝胶的方法。
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公开(公告)号:US09375513B2
公开(公告)日:2016-06-28
申请号:US13446422
申请日:2012-04-13
申请人: Wenquan Sun , Melissa Richter Bowley , Raghav Goel
发明人: Wenquan Sun , Melissa Richter Bowley , Raghav Goel
IPC分类号: A61L27/54 , A61L27/58 , A61K9/00 , A61L27/36 , A61L27/20 , A61L27/24 , A61L27/26 , A61L27/38 , A61K38/18 , A61K38/19 , A61K35/35 , A61K35/545 , A61L2/08 , A61L2/20
CPC分类号: A61L27/24 , A61F2/02 , A61K35/35 , A61K35/545 , A61K38/18 , A61K38/19 , A61L2/081 , A61L2/087 , A61L2/206 , A61L27/20 , A61L27/26 , A61L27/362 , A61L27/3687 , A61L27/3691 , A61L27/3834 , A61L27/54 , A61L27/56 , A61L2430/34 , C08L5/02
摘要: Methods of making tissue fillers are provided. In certain embodiments, the tissue is flake-like and has regenerative properties.
摘要翻译: 提供制备组织填料的方法。 在某些实施方案中,组织是片状的并且具有再生性质。
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公开(公告)号:US20130280801A1
公开(公告)日:2013-10-24
申请号:US13868588
申请日:2013-04-23
申请人: Wenquan Sun
发明人: Wenquan Sun
IPC分类号: A61K35/12
CPC分类号: A61K35/12 , A61L27/222 , A61L27/3683 , A61L27/3834 , A61L27/48 , A61L27/52 , A61L27/54 , A61L2300/258 , A61L2300/402 , A61L2300/41 , A61L2300/414 , A61L2300/426 , A61L2300/43 , A61L2300/64 , A61L2400/06 , A61L2430/34 , A61L2430/40
摘要: Disclosed herein are flowable tissue matrix compositions comprising small pieces of partially or completely decellularized tissue suspended in a gelatinized tissue or gelatin gel comprising partially or completely decellularized tissue or synthetic gelatin. The flowable tissue matrix compositions can contain factors that promote or enhance native cell migration, proliferation, and/or revascularization after implantation into a subject. Also disclosed are methods of making and using the flowable tissue matrix compositions. The compositions can be implanted into a tissue in need of repair, regeneration, healing, treatment, and/or alteration, and can promote or enhance native cell migration, proliferation, and/or revascularization.
摘要翻译: 本文公开了可流动组织基质组合物,其包含悬浮在凝胶化组织中的部分或完全脱细胞组织的小块或包含部分或完全脱细胞组织或合成明胶的明胶凝胶。 可流动的组织基质组合物可以包含在植入受试者之后促进或增强天然细胞迁移,增殖和/或血运重建的因素。 还公开了制造和使用可流动组织基质组合物的方法。 可以将组合物植入需要修复,再生,愈合,治疗和/或改变的组织中,并且可以促进或增强天然细胞迁移,增殖和/或血运重建。
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公开(公告)号:US10478168B2
公开(公告)日:2019-11-19
申请号:US13294222
申请日:2011-11-11
申请人: Wenquan Sun , Gary Monteiro
发明人: Wenquan Sun , Gary Monteiro
摘要: Devices and methods for treating an abdominal incision or hernia are described. An implant for the restoration or prophylactic treatment of an abdominal wall comprises an elongate element and at least one sheet connected to the elongate element along a longitudinal axis of the elongate element. The elongate element is positioned along the line of incision, and the at least one sheet is secured to the abdominal muscles surrounding the incision.
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公开(公告)号:US20130236439A1
公开(公告)日:2013-09-12
申请号:US13777153
申请日:2013-02-26
申请人: Wenquan Sun , Xiaohua Yu
发明人: Wenquan Sun , Xiaohua Yu
IPC分类号: A61K38/48
CPC分类号: A61K38/4886 , A61L27/24 , A61L27/3604 , A61L27/362 , A61L27/3687 , A61L27/54 , A61L2300/254
摘要: Devices and methods for treating defects in connective tissue are provided along with methods for making such devices. The devices can include enzyme-activated acellular tissue matrices that facilitate regrowth of the damaged tissue.
摘要翻译: 提供了用于治疗结缔组织缺陷的装置和方法以及用于制造这种装置的方法。 该装置可以包括促进受损组织的再生长的酶激活的无细胞组织基质。
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公开(公告)号:US20120263763A1
公开(公告)日:2012-10-18
申请号:US13446422
申请日:2012-04-13
申请人: Wenquan Sun , Melissa Richter Bowley , Raghav Goel
发明人: Wenquan Sun , Melissa Richter Bowley , Raghav Goel
CPC分类号: A61L27/24 , A61F2/02 , A61K35/35 , A61K35/545 , A61K38/18 , A61K38/19 , A61L2/081 , A61L2/087 , A61L2/206 , A61L27/20 , A61L27/26 , A61L27/362 , A61L27/3687 , A61L27/3691 , A61L27/3834 , A61L27/54 , A61L27/56 , A61L2430/34 , C08L5/02
摘要: Methods of making tissue fillers are provided. In certain embodiments, the tissue is flake-like and has regenerative properties.
摘要翻译: 提供制备组织填料的方法。 在某些实施方案中,组织是片状的并且具有再生性质。
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