Face-to-face/face-to-edge interactive chiral selectors and related
apparatuses
    1.
    发明授权
    Face-to-face/face-to-edge interactive chiral selectors and related apparatuses 失效
    面对面/面对面交互式手写选择器及相关设备

    公开(公告)号:US5674387A

    公开(公告)日:1997-10-07

    申请号:US470848

    申请日:1995-06-06

    CPC分类号: C07C51/487 C07C275/30

    摘要: The invention relates to a chiral selector useful in separating underivatized enantiomers of nonsteroidal anti-inflammatory agents, particularly naproxen and other arylacetic acid compounds, and relates to a process for achieving such separation utilizing the chiral selector, which is also useful in achieving the enantiomeric separation of amines, alcohol derivatives, epoxides and sulfoxides. The invention is also directed to an apparatus which comprises the chiral selectors.

    摘要翻译: 本发明涉及可用于分离非甾体抗炎剂,特别是萘普生和其它芳基乙酸化合物的未衍生化对映异构体的手性选择剂,涉及使用手性选择剂实现这种分离的方法,其也可用于实现对映体分离 的胺,醇衍生物,环氧化物和亚砜。 本发明还涉及一种包括手性选择器的装置。

    High performance chiral selector
    4.
    发明授权
    High performance chiral selector 失效
    高性能手性选择器

    公开(公告)号:US5290440A

    公开(公告)日:1994-03-01

    申请号:US902616

    申请日:1992-06-23

    摘要: A high performance chiral selector having the formula: ##STR1## wherein Ar is a monocyclic or ortho-fused polycyclic aromatic moiety having up to 10 ring carbon atoms, either of which may be unsubstituted or substituted with one or more C.sub.1 to C.sub.6 alkyl, C.sub.1 to C.sub.6 alkoxy, NO.sub.2, N(R.sub.5).sub.3.sup.+, CN, COOR.sub.6, SO.sub.3 H and COR.sub.7 groups wherein R.sub.5, R.sub.6 and R.sub.7 are each independently hydrogen or C.sub.1 to C.sub.6 alkyl;R.sub.1 and R.sub.2 ar each independently hydrogen, C.sub.1 to C.sub.6 alkyl or phenyl;R.sub.3 and R.sub.4 are each independently C.sub.1 to C.sub.12 alkyl or C.sub.2 to C.sub.12 alkenyl; andm and n are each independently zero or 1, said compound being an R or an S enantiomer or a mixture of R and S enantiomers.

    摘要翻译: 具有下式的高性能手性选择剂:其中Ar是具有至多10个环碳原子的单环或邻 - 稠合多环芳族部分,其中任一个可以是未取代的或被一个或多个C 1 -C 6烷基取代,C 1 至C 6烷氧基,NO 2,N(R 5)3+,CN,COOR 6,SO 3 H和COR 7基团,其中R 5,R 6和R 7各自独立地为氢或C 1至C 6烷基; R 1和R 2各自独立地为氢,C 1至C 6烷基或苯基; R 3和R 4各自独立地为C 1至C 12烷基或C 2至C 12烯基; 并且m和n各自独立地为0或1,所述化合物是R或S对映体或R和S对映异构体的混合物。

    High performance chiral selector
    5.
    发明授权
    High performance chiral selector 失效
    高性能手性选择器

    公开(公告)号:US5422004A

    公开(公告)日:1995-06-06

    申请号:US127931

    申请日:1993-09-27

    摘要: A high performance chiral selector having the formula: ##STR1## wherein Ar is a monocyclic or ortho-fused polycyclic aromatic moiety having up to 10 ring carbon atoms, either of which may be unsubstituted or substituted with one or more C.sub.1 to C.sub.6 alkyl, C.sub.1 to C.sub.6 alkoxy, NO.sub.2, N(R.sub.5).sub.3.sup.+, CN, COOR.sub.6 SO.sub.3 H and COR.sub.7 groups wherein R.sub.5, R.sub.6 and R.sub.7 are each independently hydrogen or C.sub.1 to C.sub.6 alkyl;R.sub.1 and R.sub.2 are each independently hydrogen, C.sub.1 to C.sub.6 alkyl or phenyl;R.sub.3 and R.sub.4 are each independently C.sub.1 to C.sub.12 alkyl or C.sub.2 to C.sub.12 alkenyl; andm and n are each independently zero or 1, said compound being an R or an S enantiomer or a mixture of R and S enantiomers.

    摘要翻译: 具有下式的高性能手性选择剂:其中Ar是具有至多10个环碳原子的单环或邻 - 稠合多环芳族部分,其中任一个可以是未取代的或被一个或多个C 1 -C 6烷基取代,C 1 至C 6烷氧基,NO 2,N(R 5)3+,CN,COOR 6 SO 3 H和COR 7基团,其中R 5,R 6和R 7各自独立地为氢或C 1至C 6烷基; R 1和R 2各自独立地为氢,C 1至C 6烷基或苯基; R 3和R 4各自独立地为C 1至C 12烷基或C 2至C 12烯基; 并且m和n各自独立地为0或1,所述化合物是R或S对映体或R和S对映异构体的混合物。