Cell carrier, methods of making and use
    3.
    发明授权
    Cell carrier, methods of making and use 有权
    细胞载体,制备和使用方法

    公开(公告)号:US09453196B2

    公开(公告)日:2016-09-27

    申请号:US13287611

    申请日:2011-11-02

    IPC分类号: C12N5/071 C12N5/00

    摘要: A method of culturing adherent cells is provided, wherein the method comprises providing a carrier for growing the cells, comprising one or more surfaces; and one or more relief features/indentations are present on one or more of the surfaces, wherein the carrier has a length at least about 0.2 mm, a width at least about 0.2 mm, and a height in a range from about 0.012 mm to 0.5 mm; and wherein each of the relief features/indentations has a height above the surfaces in a range from about 2 to 200 μm, and width in a range from about 20 to 200 μm; seeding the cells on the carriers; and growing the cells on the carrier.

    摘要翻译: 提供培养贴壁细胞的方法,其中所述方法包括提供用于生长所述细胞的载体,包含一个或多个表面; 并且在一个或多个表面上存在一个或多个消除特征/凹陷,其中载体具有至少约0.2mm,宽度至少约0.2mm的长度,以及在约0.012mm至0.5的范围内的高度 毫米 并且其中每个所述浮雕特征/压痕的表面高度在约2至200μm的范围内,宽度在约20至200μm的范围内; 将细胞接种在载体上; 并在载体上生长细胞。

    CELL CARRIER, METHODS OF MAKING AND USE
    5.
    发明申请
    CELL CARRIER, METHODS OF MAKING AND USE 有权
    细胞载体,制备和使用方法

    公开(公告)号:US20120156773A1

    公开(公告)日:2012-06-21

    申请号:US13287611

    申请日:2011-11-02

    IPC分类号: C12N5/071 C12N5/077

    摘要: A method of culturing adherent cells is provided, wherein the method comprises providing a carrier for growing the cells, comprising one or more surfaces; and one or more relief features/indentations are present on one or more of the surfaces, wherein the carrier has a length at least about 0.2 mm, a width at least about 0.2 mm, and a height in a range from about 0.012 mm to 0.5 mm; and wherein each of the relief features/indentations has a height above the surfaces in a range from about 2 to 200 μm, and width in a range from about 20 to 200 μm; seeding the cells on the carriers; and growing the cells on the carrier.

    摘要翻译: 提供培养贴壁细胞的方法,其中所述方法包括提供用于生长所述细胞的载体,包含一个或多个表面; 并且在一个或多个表面上存在一个或多个消除特征/凹陷,其中载体具有至少约0.2mm,宽度至少约0.2mm的长度,以及在约0.012mm至0.5的范围内的高度 毫米 并且其中每个所述浮雕特征/压痕的表面高度在约2至200μm的范围内,宽度在约20至200μm的范围内; 将细胞接种在载体上; 并在载体上生长细胞。

    Microstructures for reducing noise of a fluid dynamic structure
    8.
    发明授权
    Microstructures for reducing noise of a fluid dynamic structure 有权
    用于减少流体动力结构噪声的微结构

    公开(公告)号:US08460779B2

    公开(公告)日:2013-06-11

    申请号:US13075795

    申请日:2011-03-30

    IPC分类号: B32B3/00 B32B3/28 B32B3/30

    摘要: A fluid dynamic structure includes a surface and a microstructure mounted on the surface. The microstructure is defined by a plurality of peaks and valleys (i.e., riblets) and includes a transition region in which each peak and valley changes from a first profile to a second profile along a chord length of the structure. The peaks and/or valleys may have a variable dimension along the length of the microstructure. The peaks and valleys can be non-linear along the chord length and have a smooth transition from the first profile to the second profile. The different profiles of the microstructure are optimized to reduce noise generated by turbulent fluid flow across the structure.

    摘要翻译: 流体动力学结构包括安装在表面上的表面和微结构。 微结构由多个峰和谷(即,肋)限定,并且包括其中每个峰和谷沿着结构的弦长从第一轮廓变化到第二轮廓的过渡区域。 峰和/或谷可以沿着微结构的长度具有可变的尺寸。 峰和谷可以沿着弦长度是非线性的,并且具有从第一轮廓到第二轮廓的平滑过渡。 微结构的不同轮廓被优化,以减少通过结构的湍流流体产生的噪声。