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    Apparatuses and methods for determining protease activity
    2.
    发明申请
    Apparatuses and methods for determining protease activity 失效
    用于测定蛋白酶活性的装置和方法

    公开(公告)号：US20060121552A1

    公开(公告)日：2006-06-08

    申请号：US11224585

    申请日：2005-09-12

    申请人： William Ward

    发明人： William Ward

    IPC分类号： C12Q1/37 ,  C12P21/06 ,  C12M1/34 ,  C07K14/47

    CPC分类号： C12Q1/37 ,  C07K14/43595 ,  C07K2319/00 ,  C07K2319/21

    摘要： The present invention relates to compositions and an apparatuses for determining protease activity. The compositions of the invention contain a reporter protein fused to at least one protease cleavage sequence, and a linker for attaching the protease cleavage sequence to a solid support. Methods for determining protease activity and characterizing proteases are also provided.

    摘要翻译： 本发明涉及用于测定蛋白酶活性的组合物和装置。 本发明的组合物含有与至少一种蛋白酶切割序列融合的报道蛋白和用于将蛋白酶切割序列连接到固体支持物的接头。 还提供了确定蛋白酶活性和表征蛋白酶的方法。

    Forming artistic works from medusae
    3.
    发明申请
    Forming artistic works from medusae 审中-公开
    从medusae形成艺术作品

    公开(公告)号：US20050249921A1

    公开(公告)日：2005-11-10

    申请号：US10838676

    申请日：2004-05-04

    申请人： William Ward

    发明人： William Ward

    IPC分类号： A01N1/00 ,  B32B1/00 ,  B44C1/18 ,  B44C5/06

    CPC分类号： B32B1/00 ,  A01N1/00 ,  B32B9/02 ,  B32B9/047 ,  B32B38/164 ,  B44C1/18 ,  B44C5/06 ,  Y10T428/24802

    摘要： A method is disclosed comprising the steps of placing a sheet on top of a first towel, placing a medusa or jellyfish on top of the sheet to form a combination sheet and medusa, and allowing the medusa to dry. The first towel may be on top of a first stack of a plurality of towels. The method may further include taking the combination sheet and medusa off of the first towel, and placing it into a first bath. The combination sheet and medusa may be taken out of the first bath and placed into a second bath. The method may further include taking taking the combination sheet and medusa out of the second bath, placing it on top of a second towel, and allowing the medusa to dry. The method may also include applying color to the medusa.

    摘要翻译： 公开了一种方法，其包括以下步骤：将片放置在第一毛巾的顶部，将水母或水母放置在片材的顶部上以形成组合片和美杜莎，并允许水母干燥。 第一个毛巾可以在多个毛巾的第一堆叠的顶部。 该方法还可以包括从第一毛巾取出组合片和水母，并将其放入第一浴中。 组合片和美杜莎可以从第一个浴中取出并放入第二个浴中。 该方法可以进一步包括将组合片和水母从第二浴中取出，将其放置在第二毛巾的顶部，并允许水母干燥。 该方法还可以包括将颜色应用于美杜莎。

    Multiple disks in a single disk package
    7.
    发明授权
    Multiple disks in a single disk package 有权
    单个磁盘包中的多个磁盘

    公开(公告)号：US07760463B2

    公开(公告)日：2010-07-20

    申请号：US11612528

    申请日：2006-12-19

    申请人： William Ward ,  P. Keith Muller

    发明人： William Ward ,  P. Keith Muller

    IPC分类号： G11B5/55

    CPC分类号： G11B21/025 ,  G11B17/038 ,  G11B25/043

    摘要： A disk drive having a single drive motor and multiple platters that incorporates two discrete data paths, actuators and heads to the disk platters. Utilizing the economy of very large capacity disk platters, two or more disk drives can be created within a single physical enclosure. These two disks will be share many common parts such as the drive enclosure and spindle motor, but will have the performance and appearance to the system as two or more independent disks. Instead of having one actuator arm, the virtual disks will have two or more actuator arms and two or more sets of digital electronics. The storage on all the platters is divided up among the actuators so that no storage location is shared, but all the actuators will operate concurrently. Each actuator will have exclusive use of a subset of the data storage. Disks normally only have one actuator connected to multiple heads, at least one per surface, which only allow a single data seek and data transfer at a time. The virtual disks will have two or more actuators, one for each virtual disk, improving performance for the capacity of the platters through concurrent data seeks and transfers to different data areas.

    摘要翻译： 具有单个驱动电动机和多个盘片的磁盘驱动器，其将两个离散数据路径，致动器和磁头组合到磁盘盘片。 利用大容量磁盘盘的经济性，可以在单个物理外壳内创建两个或多个磁盘驱动器。 这两个磁盘将共享许多常见的部分，如驱动器机箱和主轴电机，但将具有作为两个或多个独立磁盘的系统的性能和外观。 代替具有一个致动器臂，虚拟盘将具有两个或更多个致动器臂和两组或多组数字电子装置。 在所有的盘片上的存储器在执行器之间被分开，使得没有共享存储位置，但是所有致动器将同时运行。 每个执行器将独占使用数据存储的子集。 磁盘通常只有一个执行器连接到多个磁头，每个表面至少有一个，这样一来只允许单次数据搜索和数据传输。 虚拟磁盘将具有两个或更多个执行器，每个虚拟磁盘一个，通过并发数据查找和传输到不同的数据区域，提高了盘片容量的性能。

    Dynamic query and step routing between systems tuned for different objectives
    8.
    发明申请
    Dynamic query and step routing between systems tuned for different objectives 有权
    针对不同目标的系统之间的动态查询和步骤路由

    公开(公告)号：US20090132471A1

    公开(公告)日：2009-05-21

    申请号：US11985910

    申请日：2007-11-19

    申请人： Douglas P. Brown ,  Scott E. Gnau ,  John Mark Morris ,  William Ward

    发明人： Douglas P. Brown ,  Scott E. Gnau ,  John Mark Morris ,  William Ward

    IPC分类号： G06F17/30

    CPC分类号： G06F17/30545 ,  G06F17/30306

    摘要： A computer-implemented apparatus, method, and article of manufacture manage a plurality of database systems. A domain includes a plurality of database systems. Each of the database systems is tuned for a particular type of workload. A virtual regulator (or multiple virtual regulators running in parallel) manages the domain and routes a set of one or more queries to a particular database system within the domain based on a cost function for each database system.

    摘要翻译： 计算机实现的装置，方法和制品管理多个数据库系统。 域包括多个数据库系统。 每个数据库系统都针对特定类型的工作负载进行调整。 基于每个数据库系统的成本函数，虚拟调节器（或并行运行的多个虚拟调节器）管理域并将一组一个或多个查询路由到域内的特定数据库系统。

    Slurry composition containing non-ionic polymer and method for use
    9.
    发明申请
    Slurry composition containing non-ionic polymer and method for use 有权
    含非离子聚合物的浆料组合物及其使用方法

    公开(公告)号：US20090126713A1

    公开(公告)日：2009-05-21

    申请号：US12317254

    申请日：2008-12-19

    申请人： Steven Grumbine ,  Chul Woo Nam ,  William Ward ,  Ramasubramanyam Nagarajan

    发明人： Steven Grumbine ,  Chul Woo Nam ,  William Ward ,  Ramasubramanyam Nagarajan

    IPC分类号： B28D1/08 ,  C10M169/04 ,  C10M145/40 ,  C10M149/10 ,  C10M145/04 ,  C10M125/26 ,  C10M155/02 ,  C10M149/20

    CPC分类号： B28D5/007 ,  B28D1/08 ,  C09K3/1463 ,  C10M125/08 ,  C10M173/02 ,  C10M2201/061 ,  C10M2201/10 ,  C10M2209/04 ,  C10M2209/12 ,  C10M2217/028 ,  C10N2240/401 ,  Y02P70/179

    摘要： A wiresaw cutting fluid composition of the present invention comprises about 25 to about 75% by weight of a particulate abrasive suspended in an aqueous carrier containing a polymeric viscosity modifier that comprises a polymer including a majority of non-ionic monomer units (preferably 100 mol % non-ionic monomer units), has a number average molecular weight (Mn) of at least about 5 kDa, and is present in the composition at a concentration sufficient to provide a Brookfield viscosity for the composition in the range of about 50 to about 1000 cP, e.g., 50 to about 700 cP, at about 25° C. at a spindle rotation rate of about 60 rpm. In one embodiment, the viscosity modifier comprises a polymer having a weight average molecular weight (Mw) of at least about 200 kDa. When a viscosity modifier of 200 kDa or greater Mw is utilized, a preferred wiresaw cutting method the cutting fluid is circulated and applied by pumps and nozzles operating at a relatively low shear rate of not more than about 104 s−1.

    摘要翻译： 本发明的线切割液组合物包含约25至约75重量％的悬浮在含有载体的水性载体中的颗粒磨料，所述颗粒磨料包含聚合物粘度调节剂，其包含大部分非离子单体单元的聚合物（优选为100摩尔％ 非离子单体单元）具有至少约5kDa的数均分子量（Mn），并且以足以提供组合物的Brookfield粘度在约50至约1000范围内的浓度存在于组合物中 cP，例如50至约700cP，在约25℃下以约60rpm的主轴转速进行。 在一个实施方案中，粘度调节剂包含重均分子量（Mw）为至少约200kDa的聚合物。 当使用200kDa或更大的Mw的粘度调节剂时，优选的切线切割方法是通过以不大于约104s -1的较低剪切速率操作的泵和喷嘴循环施加切削液。