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    APPARATUS FOR OPTICAL BODY ANALYSIS
    3.
    发明申请
    APPARATUS FOR OPTICAL BODY ANALYSIS 审中-公开
    用于光学身体分析的装置

    公开(公告)号：US20100087739A1

    公开(公告)日：2010-04-08

    申请号：US12442603

    申请日：2007-09-25

    申请人： Gerhardus Wilhelmus Lucassen ,  Wouter Harry Jacinth Rensen

    发明人： Gerhardus Wilhelmus Lucassen ,  Wouter Harry Jacinth Rensen

    IPC分类号： A61B6/00 ,  G01N21/47 ,  G01J4/00

    CPC分类号： A61B5/0059 ,  A61B5/441 ,  A61B5/6843 ,  A61B2562/146

    摘要： An apparatus for optical body analysis is built with an illumination and detection head, and an optical coupler. The illumination and detection head comprises a light source for illuminating a body portion to analyze through the optical coupler and a detector for receiving light diffusely reflected by the body portion. The optical coupler is mechanically decoupled from the illumination and detection head and is adapted to be in contact with an outer surface of the body portion while the contact between the optical coupler and the body portion minimally affects physical properties of the body portion. The apparatus may further comprise a position unit adapted to adjust the position of the illumination and detection head relative to the optical coupler so that the detector receives through the optical coupler light generated by the light source and diffusely reflected by the body portion.

    摘要翻译： 用于光学体分析的装置由照明和检测头以及光耦合器构成。 照明和检测头包括用于照亮身体部分以通过光耦合器分析的光源和用于接收由身体部分漫反射的光的检测器。 光耦合器与照明和检测头机械地分离，并且适于与主体部分的外表面接触，同时光耦合器和主体部分之间的接触最小程度地影响主体部分的物理特性。 该装置还可以包括位置单元，其适于调整照明和检测头相对于光学耦合器的位置，使得检测器通过光耦合器接收由光源产生的并被身体部分漫反射的光。

    EXTERNAL MICROCONTROLLER FOR LED LIGHTING FIXTURE, LED LIGHTING FIXTURE WITH INTERNAL CONTROLLER, AND LED LIGHTING SYSTEM
    5.
    发明申请
    EXTERNAL MICROCONTROLLER FOR LED LIGHTING FIXTURE, LED LIGHTING FIXTURE WITH INTERNAL CONTROLLER, AND LED LIGHTING SYSTEM 审中-公开
    LED照明灯具外置微控制器，内置控制器LED灯具及LED照明系统

    公开(公告)号：US20100002223A1

    公开(公告)日：2010-01-07

    申请号：US12513921

    申请日：2007-11-13

    申请人： Cristian Presura ,  Gary Nelson Garcia Molina ,  Markus Laubscher ,  Gerhardus Wilhelmus Lucassen

    发明人： Cristian Presura ,  Gary Nelson Garcia Molina ,  Markus Laubscher ,  Gerhardus Wilhelmus Lucassen

    IPC分类号： G01C3/08 ,  G01P3/36

    CPC分类号： G01B9/02092

    摘要： A detector (210, 310) that is configured to detect ghost-coherent reflections (260) produced by a superluminescent diode (SLD). The ghost reflections (260) are detected based on the optical coherence produced by reflections from surfaces (350, 450, 555) that are at integer multiples of the reflections within the SLD cavity (213), and thus exhibit the fine resolution discrimination that is typical of optical coherent detectors. In a preferred embodiment, the detector (210, 310) is configured to detect ghost reflections (260) from a surface at a particular multiple of the internal reflections. Ghost reflections (260) at other multiples are optically attenuated (330), or, if such reflections are known to be non-varying, canceled via a calibration procedure.

    摘要翻译： 被配置为检测由超发光二极管（SLD）产生的重影相干反射（260）的检测器（210,310）。 基于由SLD腔（213）内的反射的整数倍的表面（350,450,555）的反射产生的光学相干性来检测幻像反射（260），从而表现出精细的分辨率辨别 典型的光学相干检测器。 在优选实施例中，检测器（210,310）被配置为在内部反射的特定倍数处从表面检测重影反射（260）。 在其他倍数处的幽灵反射（260）被光学衰减（330），或者如果已知这种反射是不变的，则通过校准程序被取消。

    Classification of tumor tissue with a personalized threshold
    6.
    发明授权
    Classification of tumor tissue with a personalized threshold 有权
    具有个性化阈值的肿瘤组织分类

    公开(公告)号：US09498136B2

    公开(公告)日：2016-11-22

    申请号：US14112555

    申请日：2012-04-10

    申请人： Gerhardus Wilhelmus Lucassen ,  Bernardus Hendrikus Wilhelmus Hendriks ,  Rami Nachabe

    发明人： Gerhardus Wilhelmus Lucassen ,  Bernardus Hendrikus Wilhelmus Hendriks ,  Rami Nachabe

    IPC分类号： A61B5/00 ,  A61B1/00 ,  G01N21/64

    CPC分类号： A61B5/0075 ,  A61B1/00 ,  A61B5/0071 ,  A61B5/0084 ,  A61B5/0091 ,  A61B5/4887 ,  A61B5/6848 ,  A61B5/6852 ,  G01N21/64 ,  G01N2021/6421

    摘要： The present invention deals with discrimination of malignant tissue from normal and benign tissue in a single patient on the basis of optical spectroscopic measurements. Starting from spectroscopic measurements in normal tissue, reference values are obtained for the normal class. With spectroscopic measurements in other tissues data points can be assigned to new class(es) when the spectral characteristics fall outside a threshold defining the reference class. Thresholds between different classes can also be defined. Finding (the transition to) malignant tissue is based on comparing the spectroscopic values to the classification threshold discriminating normal and benign versus malignant tissue. Thus, the basis of normal spectroscopic measurements is tuned to the individual patient characteristic. Discriminating the normal plus benign and malignant from that reference is more efficient compared to the reference of the all patient database.

    摘要翻译： 本发明基于光学光谱测量法处理单个患者中恶性组织与正常和良性组织的鉴别。 从正常组织中的光谱测量开始，获得正常类的参考值。 通过在其他组织中的光谱测量，当光谱特性落在定义参考类的阈值之外时，可以将数据点分配给新类。 也可以定义不同类之间的阈值。 寻找（过渡到）恶性组织是基于将光谱值与鉴别正常和良性与恶性组织的分类阈值进行比较。 因此，正常光谱测量的基础被调整到个体患者的特征。 与所有患者数据库的参考相比，从该参考文献中区分正常和良性和恶性的效果更高。

    Apparatus for depth-resolved measurements of properties of tissue
    10.
    发明授权
    Apparatus for depth-resolved measurements of properties of tissue 失效
    用于深度分辨测量组织性质的装置

    公开(公告)号：US08417323B2

    公开(公告)日：2013-04-09

    申请号：US12302053

    申请日：2007-05-30

    申请人： Natallia Uzunbajakava ,  Rachel Estelle Thilwind ,  Joachim Kahlert ,  Gerhardus Wilhelmus Lucassen

    发明人： Natallia Uzunbajakava ,  Rachel Estelle Thilwind ,  Joachim Kahlert ,  Gerhardus Wilhelmus Lucassen

    IPC分类号： A61B6/00

    CPC分类号： A61B5/0086 ,  A61B5/0084 ,  A61B5/1459 ,  A61B18/24 ,  A61B2562/0242

    摘要： An apparatus for depth-resolved measurements of properties of tissue includes an illuminator that illuminates the tissue with light, a collector for collecting light which has not been absorbed by the tissue, and a determination device configured to determine properties of the tissue in different depths from the collected light. A casing for advancing into a hollow object includes at least a part of the illuminator and collector. The illuminator and collector are configured to collect light depth-resolved, and the determination device is configured to determine depth-resolved properties of the tissue from the light which has been collected depth-resolved.

    摘要翻译： 用于对组织性质进行深度分辨测量的装置包括用光照射组织的照明器，用于收集未被组织吸收的光的收集器;以及确定装置，其被配置为确定不同深度的组织的性质 收集的光。 用于前进到中空物体的壳体包括照明器和收集器的至少一部分。 照明器和收集器被配置为收集深度分辨的光，并且确定装置被配置为确定已经被深度分辨的光的组织的深度分辨特性。