摘要:
A side lobe suppression method for an SAR image based on the deformation of a spatial spectral support area is provided. Using the relationship between the spatial spectral support area distribution of an SAR system and an impulse response, the trend of a side lobe in the impulse response is changed by deforming the spatial spectral support area; two SAR images with different side lobe trends are obtained by calculation; the difference information of the side lobe trends between the two SAR images is finally utilized to realize the mutual separation of a target main lobe and the side lobe, thus realizing effective side lobe suppression. The method has an obvious effect on side lobe suppression without losing image resolution, at the same time, can be realized simply, has less calculation amount, is not sensitive to noise, is also very convenient to implement, and can be directly used for processing an original SAR image.
摘要:
A class of polycyclic compounds of general formula (I), wherein Base1, Base2, Y, Za, Xa, Xa1, Xb, Xb1, Xc, Xc1, Xd, Xd1, R1, R1a, R2, R2a, R3, R4, R4a, R5, R6, R6a, R7, R7a, R8, R8a, and R9 are defined herein, that may be useful as inductors of type I interferon production, specifically as STING active agents, are provided. Also provided are processes for the synthesis and use of compounds.
摘要:
The present invention is directed to substituted certain 1-pyrazolyl, 5-, 6-disubstituted indazole derivatives of Formula (I) and pharmaceutically acceptable salts thereof, wherein R1, R2, and ring A are as defined herein, which are potent inhibitors of LRRK2 kinase and may be useful in the treatment or prevention of diseases in which the LRRK2 kinase is involved, such as Parkinson's Disease and other diseases and disorders described herein. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of diseases, such as Parkinson's disease, in which LRRK-2 kinase is involved.
摘要:
In one embodiment, a method includes accessing a mapping that represents a correspondence between a column in a source database and a column in a temporary storage table, in response to receiving a data operation request to execute a data operation on a column of the source database. The method further includes changing the temporary storage table by executing the data operation on the temporary storage table and performing a reconstruction operation using data from the temporary storage table and the source database.
摘要:
This invention relates to novel rationale and methods for identifying human and primate taste-specific genes, including genes involved in salty taste perception, especially human salty taste perception, but also genes involved in sweet, bitter, umami, and sour taste perception, and genes involved in other taste cell or taste receptor related activities such as digestive function and digestive related diseases, taste cell turnover, immunoregulation of the oral and digestive tract, and metabolic regulation such as in diabetes and obesity, the genes identified using these methods, and assays for identifying taste modulators (enhancers or blockers) and potential therapeutics using these genes. These compounds have potential application in modulating (enhancing or blocking) taste perception, especially salty taste perception and as potential therapeutics. In addition, this invention relates to novel methods for identifying taste-specific genes that can be used as markers for different taste cell types, including sweet, bitter, umami, sour, salty, and other taste cells in mammals as well as assays that measure the activity of the sweet, bitter, umami, or sour receptor in the presence of these genes to identify modulators of sweet, bitter, umami, and sour taste and to identify therapeutics especially for treating digestive or metabolic disorders, taste loss, and oral infections. Particularly, the genes identified herein and antibodies or oligos thereto can be used as markers to identify and/or purify specific taste cells e.g., from taste cell suspensions by use of FACS or magnetic bead cell selection or other known cell purification and isolation procedures.
摘要:
A system and method that facilitates processing and/or routing of emergency call in an IMS (IP Multimedia Subsystem) for VoIP (Voice over IP) subscribers is provided. Specifically, an E911 profile is generated, for example, by an application server, for each VoIP subscriber based in part on current location information associated with the subscriber, such as, the subscriber's IP address. The E911 profile is pushed to the HSS (Home Subscriber Server) of the IMS. The E911 profile can then be stored in the HSS and can be queried by an E-CSCF (Emergency Call Session Control Function) during emergency call processing. Moreover, when an emergency call is received from the subscriber, the E-CSCF can retrieve the E911 profile associated with the subscriber from the HSS and route the call to an appropriate PSAP (Public Safety Answering Point) based on an analysis of the information in the E911 profile.
摘要:
A method for providing multimedia services to subscriber user equipment (UE) within an IP multimedia subsystem network (IMS) may include configuring the IMS to enable a single UE to fork register and cooperate with multiple serving-call session control functions (S-CSCFs). After obtaining IP connectivity, the single UE signals to register with the IMS and the IMS determines whether the UE is configured to fork register with multiple S-CSCFs. If the UE is configured, the IMS determines which S-CSCFs are eligible for the UE registration and fork registers the UE to multiple S-CSCFs of the eligible S-CSCFs. Consequently, incoming and outgoing calls to/from the UE are routed by the IMS to any of the multiple registered S-CSCFs.
摘要:
A heat sink includes a fin assembly including a plurality of fins and a plate type heat pipe attached to the fin assembly. The plate type heat pipe includes a sealed shell in which a working fluid is filled, a wick layer formed on an inner face of the shell and a supporting member disposed in the shell. The supporting member includes a plurality of supporting portions and a plurality of bodies connecting the supporting portions. Each supporting portion includes a plurality of convex portions contacting a top of the wick layer and a plurality of concave portions contacting a bottom of the wick layer. The convex portions and the concave portions of each supporting portion are alternately arranged. Each convex portion and an adjacent concave portion cooperatively enclose a first through hole for the working fluid flowing therethrough.
摘要:
A method for building wizard-style user interfaces (UIs) for a business task is disclosed. The method includes receiving metadata at a computer system, where the metadata comprises information regarding the business task, generating an analysis by analyzing the metadata, generating user guidance information, and executing flow and business logic of the business task. The user guidance information is with regard to the business task, and the user guidance information is based on the analysis.
摘要:
In one embodiment, a method for facilitating long-lived data transactions includes starting a data transaction during a first user session, storing data associated with the data transaction in a temporary storage table, and ending the data transaction during a second user session using contents of the temporary storage table.