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    Particle accelerator for radiotherapy by means of ion beams
    1.
    发明授权
    Particle accelerator for radiotherapy by means of ion beams 有权
    通过离子束进行放射治疗的粒子加速器

    公开(公告)号：US07906769B2

    公开(公告)日：2011-03-15

    申请号：US11629805

    申请日：2005-06-16

    申请人： Klaus Blasche ,  Bernhard Franczak

    发明人： Klaus Blasche ,  Bernhard Franczak

    IPC分类号： H01J1/50

    CPC分类号： H05H15/00 ,  A61N5/1078 ,  A61N5/1079 ,  A61N2005/1087

    摘要： The invention relates to a particle accelerator for radiotherapy by means of ion beams (150). The particle accelerator comprises a sixfold synchrotron ring (100) having six rectilinear beam sections (1 to 6) and six curved beam sections (7 to 12). Injection means (43) for introducing a linearly accelerated ion beam into the synchrotron ring (100) are arranged on a first rectilinear beam section (1) of the six rectilinear beam sections (1-6). Along the course of a second rectilinear beam section (5) there is at least one acceleration means (44) for the ion beam. Extraction means (45) for extracting the internal beam highly accelerated after several circulations are provided on a third rectilinear beam section (4). Each curved beam section (7 to 12) comprises a pair of dipole magnets (13/14, 15/16, 17/18, 19/20, 21/22, 23/24). A horizontally defocusing quadrupole magnet (31 to 36) is arranged between each pair of dipole magnets (13/14, 15/16, 17/18, 19/20, 21/22, 23/24), and a horizontally focusing quadrupole magnet (25 to 30) is arranged upstream of each pair of dipole magnets (13/14, 15/16, 17/18, 19/20, 21/22, 23/24).

    摘要翻译： 本发明涉及一种借助于离子束（150）进行放射治疗的颗粒加速器。 颗粒加速器包括具有六个直线梁部分（1-6）和六个弯曲梁部分（7至12）的六重同步加速器环（100）。 用于将线性加速的离子束引入同步加速器环（100）的喷射装置（43）布置在六个直线梁部分（1-6）的第一直线梁部分（1）上。 沿着第二直线梁段（5）的过程，至少有一个用于离子束的加速装置（44）。 在第三直线光束部分（4）上提供用于提取在几次循环之后被高度加速的内部光束的提取装置（45）。 每个弯曲梁部分（7至12）包括一对偶极子磁体（13/14,15/16,17 / 18,19/20,21 / 22,23 / 24）。 水平散焦四极磁体（31至36）布置在每对偶极子磁体（13/14,15/16,17 / 18,19 / 20,21 / 22,23 / 24）之间，水平聚焦四极磁铁 （25至30）布置在每对偶极子磁体（13/14,15/16,17 / 18,19/20,21 / 22,23 / 24）的上游。

    Apparatus and method for compensation of movements of a target volume during ion beam irradiation
    2.
    发明授权
    Apparatus and method for compensation of movements of a target volume during ion beam irradiation 有权
    用于在离子束照射期间补偿目标体积的运动的装置和方法

    公开(公告)号：US07482606B2

    公开(公告)日：2009-01-27

    申请号：US11148808

    申请日：2005-06-09

    申请人： Sven Oliver Groezinger ,  Thomas Haberer ,  Wolfgang Ott ,  Klaus Poppensieker

    发明人： Sven Oliver Groezinger ,  Thomas Haberer ,  Wolfgang Ott ,  Klaus Poppensieker

    IPC分类号： A61N5/00 ,  G21G5/00

    CPC分类号： A61N5/1043 ,  A61N5/1049 ,  A61N5/1067 ,  A61N2005/1061 ,  A61N2005/1074 ,  A61N2005/1087 ,  A61N2005/1095

    摘要： The invention relates to an apparatus and method for compensation of three-dimensional movements of a target volume (1) during ion beam irradiation. For the purpose, the apparatus comprises a position location and tracking system (4) for detecting the movements and a depth modulator (6) for modifying the depth of penetration of the ion beam. For the purpose of compensation, the movements are divided vectorially into a transverse component and a longitudinal component. The transverse component is compensated from irradiation point to irradiation point using the raster scanning apparatus (3) and the longitudinal component is compensated from irradiation point to irradiation point using the depth modulator (6) by means of the fact that, in addition to the change in the location of the target volume, the change in the structure of healthy tissue covering the target volume is, in the preliminaries to irradiation, detected and modelled and stored in the form of a look-up table in a memory of a movement measurement, control and read-out module SAMB and compared with the actual values during irradiation.

    摘要翻译： 本发明涉及用于在离子束照射期间补偿目标体积（1）的三维运动的装置和方法。 为此，该装置包括用于检测运动的位置位置和跟踪系统（4）和用于改变离子束穿透深度的深度调制器（6）。 为了补偿的目的，将运动向量地分成横向分量和纵向分量。 使用光栅扫描装置（3），从照射点到照射点补偿横向分量，并且通过使用深度调制器（6）的纵向分量从照射点到照射点补偿，除了改变之外 在目标体积的位置，覆盖目标体积的健康组织的结构的变化是在检测和建模的预备中，以查询表的形式在运动测量的存储器中存储， 控制和读出模块SAMB，并与照射期间的实际值进行比较。

    Irradiation Device
    3.
    发明申请
    Irradiation Device 有权
    照射装置

    公开(公告)号：US20080203323A1

    公开(公告)日：2008-08-28

    申请号：US11996498

    申请日：2006-07-20

    申请人： Georg Fehrenbacher ,  Torsten Radon

    发明人： Georg Fehrenbacher ,  Torsten Radon

    IPC分类号： A61N5/00

    CPC分类号： A61N5/10 ,  A61N5/1079 ,  A61N2005/1087 ,  A61N2005/1094 ,  G21F3/00 ,  G21F7/00

    摘要： Irradiation device (1) for proton and/or ion beam therapy, said device comprising a radiation source (3), a beam guiding device (5), and at least one therapy room (7) comprising at least one treatment site (9) and at least one access (17), into which a treatment beam (13) is directed, wherein the therapy room (7) is arranged in a first plane (E1), and the treatment beam (13) is directed into the therapy room (7) from a second plane (E2) located above or below the first plane (E1), derived therein, oriented towards the treatment site (9) so that the treatment beam (13) directed towards the treatment site (9) is directed away from the access (17); wherein in the therapy room, a shielding is provided, which is open towards the treatment site (9) and associated with the entrance region (E) of the treatment beam (13) into the therapy room (7) so that the access (17) is arranged on the side of the side of the shielding (33) opposing the treatment site (9), and wherein at least one labyrinth (L) leading from the access (17) to the treatment site (9) is provided laterally offset in relation to the treatment beam (13) proceeding in the therapy room (7) and to the shielding (33).

    摘要翻译： 用于质子和/或离子束治疗的照射装置（1），所述装置包括辐射源（3），光束引导装置（5）以及包括至少一个治疗部位（9）的至少一个治疗室（7） 以及治疗梁（13）被引导到其中的至少一个通路（17），其中所述治疗室（7）被布置在第一平面（E 1）中，并且所述治疗梁（13）被引导到所述治疗 从位于其中衍生的第一平面（E 1）上方或下方的第二平面（E 2）的房间（7）朝向治疗部位（9）定向，使得处理梁（13）朝向治疗部位（9） ）被指向远离访问（17）; 其特征在于，在治疗室中，设置有朝向治疗部位（9）开放并与处理梁（13）的入口区域（E）相连并进入治疗室（7）的屏蔽，使得通路 ）设置在与处理部位（9）相对的屏蔽部（33）侧的一侧，并且其中，从通路（17）到达治疗部位（9）的至少一个迷宫（L）被横向偏移 相对于在治疗室（7）和屏蔽（33）中进行的治疗束（13）。

    Sheet material having metal points and method for the production thereof
    5.
    发明授权
    Sheet material having metal points and method for the production thereof 失效
    具有金属点的片材及其制造方法

    公开(公告)号：US06923651B2

    公开(公告)日：2005-08-02

    申请号：US10952974

    申请日：2004-09-29

    申请人： Norbert Angert ,  Dobri Dobrev ,  Reinhard Neumann ,  Johann Vetter

    发明人： Norbert Angert ,  Dobri Dobrev ,  Reinhard Neumann ,  Johann Vetter

    IPC分类号： H01L21/48 ,  H01L23/498 ,  H05K3/00 ,  H05K3/42 ,  H01R12/00

    CPC分类号： H01L23/49827 ,  H01L21/486 ,  H01L2924/0002 ,  H05K3/002 ,  H05K3/423 ,  H05K2201/09827 ,  H05K2201/10378 ,  H05K2203/0733 ,  H05K2203/092 ,  Y10T428/24273 ,  Y10T428/24322 ,  H01L2924/00

    摘要： The invention relates to a sheet material having metal points (8) and surfaces (2 and 3) located opposite one another, wherein the sheet material (1) has through-holes (4) from one surface (2) to the surface (3) located opposite. Those through-holes (4) are filled with needle-point-shaped conical pins (5) or through-contacts (6) of electrically conducting material, whereas the surrounding sheet material in a preferred embodiment of the invention consists of an insulating plastics material (7). In a further embodiment of the invention, instead of the insulating plastics material (7) there are provided needle-shaped pins that are surrounded by air or some other gaseous medium. The invention further relates to a method for the production of such a sheet material (1) and to forms of use of the sheet material (1).

    摘要翻译： 本发明涉及具有金属点（8）和彼此相对定位的表面（2和3）的片材，其中片材（1）具有从一个表面（2）到表面（3）的通孔（4） ）位于对面。 那些通孔（4）填充有导电材料的针尖形锥形销（5）或通孔（6），而在本发明的优选实施例中，周围的片材由绝缘塑料 （7）。 在本发明的另一实施例中，代替绝缘塑料材料（7），提供了被空气或一些其它气体介质包围的针状销。 本发明还涉及生产这种片材（1）的方法和片材（1）的使用形式。

    Getter metal alloy coating and device and method for the production thereof
    7.
    发明授权
    Getter metal alloy coating and device and method for the production thereof 有权
    吸收剂金属合金涂层及其制造方法

    公开(公告)号：US07871679B2

    公开(公告)日：2011-01-18

    申请号：US10505254

    申请日：2003-02-27

    申请人： Hartmut Reich-Sprenger

    发明人： Hartmut Reich-Sprenger

    IPC分类号： H05H1/48

    CPC分类号： C23C14/564 ,  C23C14/046 ,  C23C14/16 ,  C23C14/325 ,  H01J37/32422 ,  Y10T428/12806 ,  Y10T428/12819

    摘要： The invention relates to a coating comprising a getter metal alloy and to an arrangement and method for the production thereof. The coating therein consists of a non-vaporizing getter metal alloy (2) for an inner wall (3) of a high-vacuum vessel (4). The arrangement basically consists of a metal plasma generator (7), which in turn comprises an insulator member (8), which carries an ignition electrode (9) and a cathode wire (10) comprising a getter metal alloy (2). Those three components are surrounded by a cage-like anode member (13), which together with the insulation member (8) projects into the high vacuum vessel (5) to be coated and is supplied with cathode potential (12), high-voltage ignition pulse (19) and anode potential (14) by a voltage supply device (16), the anode member (13) together with the high-vacuum vessel (4) being held at ground potential.

    摘要翻译： 本发明涉及一种包含吸气剂金属合金的涂层及其制备方法和装置。 其中的涂层由用于高真空容器（4）的内壁（3）的非汽化吸气剂金属合金（2）组成。 该装置基本上由金属等离子体发生器（7）组成，该金属等离子体发生器又包括承载点火电极（9）和包括吸气剂金属合金（2）的阴极线（10）的绝缘体构件（8）。 这三个部件被笼状阳极部件（13）包围，该阳极部件（13）与绝缘部件（8）一起投射到待涂覆的高真空容器（5）中并被供给阴极电位（12），高压 点火脉冲（19）和阳极电位（14），阳极部件（13）与高真空容器（4）一起保持接地电位。

    Irradiation Verification Device for Radiotherapy Installations, and Method for Handling Thereof
    8.
    发明申请
    Irradiation Verification Device for Radiotherapy Installations, and Method for Handling Thereof 有权
    放射治疗装置的照射验证装置及其处理方法

    公开(公告)号：US20090274273A1

    公开(公告)日：2009-11-05

    申请号：US12225197

    申请日：2007-03-12

    申请人： Cläre Hanna Von Neubeck ,  Wilma Kraft-Weyrather ,  Carola Sabine Hartel

    发明人： Cläre Hanna Von Neubeck ,  Wilma Kraft-Weyrather ,  Carola Sabine Hartel

    IPC分类号： A61N5/10 ,  G01D18/00

    CPC分类号： A61N5/1048 ,  A61N5/1071 ,  A61N2005/1076 ,  A61N2005/1087 ,  B01L3/5085

    摘要： The present invention relates to an irradiation verification apparatus (1), the irradiation verification apparatus (1) containing living cell material which is fixed in location on cell supports (3). The cell supports (3) are arranged between cell support holders (5,6). For irradiation verification, the z co-ordinate of the irradiation verification apparatus (1) is adjusted in the direction of the beam axis Z so that, after the irradiation, regions having killed cell material can be demarcated in spatial co-ordinates, with reference to an irradiation scheme, from regions having cell material of the irradiation verification apparatus (1) that is still active. A container (2) having an insert (4) for the cell supports (3) and also the cell support holders (5,6) comprise a beam-transparent material. The cell support holders (5,6) have a base plate (5) and a top plate (6), between which the cell supports (3) are arranged orthogonally to the holding plates (5,6). The holding plates (5,6) have blind holes (8,9) aligned with one another, in which the ends (10,11) of the cell supports are arranged, the cell supports (3) being solid rods (12) on the outer surfaces (13) of which the cell material is fixed.

    摘要翻译： 本发明涉及一种照射验证装置（1），该照射验证装置（1）包含固定在单元支撑体（3）上的位置的活细胞材料。 电池支撑体（3）布置在电池支撑支架（5,6）之间。 对于照射验证，照射验证装置（1）的z坐标在光束轴线Z的方向上被调节，使得在照射之后，具有杀死的细胞材料的区域可以在空间坐标中划定，参考 从具有仍然有效的照射验证装置（1）的细胞材料的区域到照射方案。 具有用于电池支撑件（3）的插入件（4）和电池支撑保持器（5,6）的容器（2）包括光束透明材料。 电池支撑保持器（5,6）具有基板（5）和顶板（6），电池支撑件（3）正好与支撑板（5,6）配置。 保持板（5,6）具有彼此对准的盲孔（8,9），其中细胞支撑件的端部（10,11）被布置，细胞支撑体（3）为实心棒（12） 电池材料固定的外表面（13）。

    Apparatus for pre-acceleration of ion beams used in a heavy ion beam application system
    9.
    发明授权
    Apparatus for pre-acceleration of ion beams used in a heavy ion beam application system 有权
    用于重离子束施加系统中使用的离子束预加速装置

    公开(公告)号：US07138771B2

    公开(公告)日：2006-11-21

    申请号：US11037572

    申请日：2005-01-18

    申请人： Alexander Bechthold ,  Ulrich Ratzinger ,  Alwin Schempp ,  Bernhard Schlitt

    发明人： Alexander Bechthold ,  Ulrich Ratzinger ,  Alwin Schempp ,  Bernhard Schlitt

    IPC分类号： H05H9/00

    CPC分类号： G21K5/04 ,  H05H7/04 ,  H05H7/08 ,  H05H2277/11

    摘要： The present invention relates to an apparatus for pre-acceleration of ions and optimized matching of beam parameters used in a heavy ion application comprising a radio frequency quadruple accelerator (RFQ) having two mini-vane pairs supported by a plurality of alternating stems accelerating the ions from about 8 keV/u to about 400 keV/u and an intertank matching section for matching the parameters of the ion beam coming from the radio frequency quadruple accelerator (RFQ) to the parameters required by a subsequent drift tube linear accelerator (DTL).

    摘要翻译： 本发明涉及一种用于预加速离子的装置和用于重离子应用中的光束参数的优化匹配，其包括具有两个微型叶片对的射频四重加速器（RFQ），所述微型叶片对由多个交替的茎支持，加速离子 从约8keV / u至约400keV / u，以及用于将来自射频四重加速器（RFQ）的离子束的参数与随后的漂移管线性加速器（DTL）所需的参数进行匹配的槽间匹配部。