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    Therapeutic magnetic control systems and contrast agents
    2.
    发明授权
    Therapeutic magnetic control systems and contrast agents 有权

    公开(公告)号：US10029008B2

    公开(公告)日：2018-07-24

    申请号：US15155386

    申请日：2016-05-16

    申请人： Pulse Therapeutics, Inc.

    发明人： Francis M. Creighton

    IPC分类号： A61N2/00 ,  H01F7/02 ,  A61B17/22 ,  A61K41/00 ,  A61N2/02 ,  A61N2/06 ,  A61K9/00 ,  A61K38/48 ,  A61B34/00 ,  A61K47/69 ,  B82Y5/00 ,  A61B17/00

    摘要： A system for the physical manipulation of free magnetic rotors in a circulatory system using a remotely placed magnetic field-generating stator is provided. In one embodiment, the invention relates to the control of magnetic particles in a fluid medium using permanent magnet-based or electromagnetic field-generating stator sources. Such a system can be useful for increasing the diffusion of therapeutic agents in a fluid medium, such as a human circulatory system, which can result in substantial clearance of fluid obstructions, such as vascular occlusions, in a circulatory system resulting in increased blood flow. Examples of vascular occlusions targeted by the system include, but are not limited to, atherosclerotic plaques, including fibrous caps, fatty buildup, coronary occlusions, arterial stenosis, restenosis, vein thrombi, arterial thrombi, cerebral thrombi, embolisms, hemorrhages, other blood clots, and very small vessels.

    DEVICES FOR CONTROLLING MAGNETIC NANOPARTICLES TO TREAT FLUID OBSTRUCTIONS
    4.
    发明申请
    DEVICES FOR CONTROLLING MAGNETIC NANOPARTICLES TO TREAT FLUID OBSTRUCTIONS 有权
    用于控制磁性纳米颗粒以治疗流体阻塞的装置

    公开(公告)号：US20120310034A1

    公开(公告)日：2012-12-06

    申请号：US13505447

    申请日：2010-11-02

    申请人： Francis M. Creighton ,  Rogers C. Ritter

    发明人： Francis M. Creighton ,  Rogers C. Ritter

    IPC分类号： A61N2/10 ,  B82Y5/00

    CPC分类号： A61K41/00 ,  A61B17/22 ,  A61B17/22012 ,  A61B34/73 ,  A61B2017/00876 ,  A61B2017/22084 ,  A61B2017/22094 ,  A61B2034/733 ,  A61K9/0019 ,  A61K38/482 ,  A61K38/484 ,  A61K47/6941 ,  A61N2/004 ,  A61N2/02 ,  A61N2/06 ,  B82Y5/00 ,  C12Y304/21007 ,  C12Y304/21068 ,  H01F7/0273 ,  Y10S977/811 ,  Y10S977/905 ,  Y10S977/909

    摘要： The present invention relates to a system for the physical manipulation of free magnetic rotors in a circulatory system using a remotely placed magnetic field-generating stator. In one aspect, the invention relates to the control of magnetic particles in a fluid medium using permanent magnet-based or electromagnetic field-generating stator sources. Such a system can be useful for increasing the diffusion of therapeutic agents in a fluid medium, such as a human circulatory system, which can result in substantial clearance of fluid obstructions, such as vascular occlusions, in a circulatory system resulting in increased blood flow. Examples of vascular occlusions targeted by the system include, but are not limited to, atherosclerotic plaques, including fibrous caps, fatty buildup, coronary occlusions, arterial stenosis, restenosis, vein thrombi, arterial thrombi, cerebral thrombi, embolisms, hemorrhages, other blood clots, and very small vessels.

    摘要翻译： 本发明涉及一种用于使用远程放置的产生磁场的定子在循环系统中物理地操纵自由磁转子的系统。 一方面，本发明涉及使用基于永磁体或电磁场产生定子源的流体介质中的磁性颗粒的控制。 这种系统可用于增加治疗剂在诸如人类循环系统的流体培养基中的扩散，其可导致循环系统中的流体障碍（例如血管闭塞）的实质性清除，导致血流量增加。 系统靶向的血管闭塞的实例包括但不限于动脉粥样硬化斑块，包括纤维帽，脂肪积聚，冠状动脉闭塞，动脉狭窄，再狭窄，静脉血栓，动脉血栓，脑血栓，栓塞，出血，其他血块 ，和非常小的船只。

    MAGNETIC PARTICLE CONTROL AND VISUALIZATION
    5.
    发明申请
    MAGNETIC PARTICLE CONTROL AND VISUALIZATION 有权

    公开(公告)号：US20210338818A1

    公开(公告)日：2021-11-04

    申请号：US17302625

    申请日：2021-05-07

    申请人： Pulse Therapeutics, Inc.

    发明人： Francis M. Creighton

    IPC分类号： A61K41/00 ,  H01F7/02 ,  A61B17/22 ,  A61B34/00 ,  A61K47/69 ,  A61N2/00 ,  A61N2/02 ,  A61N2/06 ,  A61K9/00 ,  A61K38/48

    摘要： Some embodiments provide a system for external manipulation of magnetic nanoparticles in vasculature using a remotely placed magnetic field-generating stator. In one aspect, the systems and methods relate to the control of magnetic nanoparticles in a fluid medium using permanent magnet-based or electromagnetic field-generating stator sources. Such a system can be useful for increasing the diffusion of therapeutic agents in a fluid medium, such as a human circulatory system, which can result in substantial clearance of fluid obstructions, such as vascular occlusions, in a circulatory system resulting in increased blood flow.

    DEVICES FOR CONTROLLING MAGNETIC NANOPARTICLES TO TREAT FLUID OBSTRUCTIONS
    6.
    发明申请
    DEVICES FOR CONTROLLING MAGNETIC NANOPARTICLES TO TREAT FLUID OBSTRUCTIONS 有权

    公开(公告)号：US20210283254A1

    公开(公告)日：2021-09-16

    申请号：US17079776

    申请日：2020-10-26

    申请人： Pulse Therapeutics, Inc.

    发明人： Francis M. Creighton

    IPC分类号： A61K41/00 ,  H01F7/02 ,  A61B17/22 ,  A61B34/00 ,  A61K47/69 ,  A61N2/00 ,  A61N2/02 ,  A61N2/06 ,  A61K9/00 ,  A61K38/48

    摘要： A system for the physical manipulation of free magnetic rotors in a circulatory system using a remotely placed magnetic field-generating stator is provided. In one embodiment, the invention relates to the control of magnetic particles in a fluid medium using permanent magnet-based or electromagnetic field-generating stator sources. Such a system can be useful for increasing the diffusion of therapeutic agents in a fluid medium, such as a human circulatory system, which can result in substantial clearance of fluid obstructions, such as vascular occlusions, in a circulatory system resulting in increased blood flow. Examples of vascular occlusions targeted by the system include, but are not limited to, atherosclerotic plaques, including fibrous caps, fatty buildup, coronary occlusions, arterial stenosis, restenosis, vein thrombi, arterial thrombi, cerebral thrombi, embolisms, hemorrhages, other blood clots, and very small vessels.

    Devices for controlling magnetic nanoparticles to treat fluid obstructions
    8.
    发明授权
    Devices for controlling magnetic nanoparticles to treat fluid obstructions 有权
    用于控制磁性纳米颗粒以治疗流体障碍物的装置

    公开(公告)号：US08715150B2

    公开(公告)日：2014-05-06

    申请号：US13505447

    申请日：2010-11-02

    申请人： Francis M. Creighton

    发明人： Francis M. Creighton

    IPC分类号： A61M37/00 ,  A61N2/00

    CPC分类号： A61K41/00 ,  A61B17/22 ,  A61B17/22012 ,  A61B34/73 ,  A61B2017/00876 ,  A61B2017/22084 ,  A61B2017/22094 ,  A61B2034/733 ,  A61K9/0019 ,  A61K38/482 ,  A61K38/484 ,  A61K47/6941 ,  A61N2/004 ,  A61N2/02 ,  A61N2/06 ,  B82Y5/00 ,  C12Y304/21007 ,  C12Y304/21068 ,  H01F7/0273 ,  Y10S977/811 ,  Y10S977/905 ,  Y10S977/909

    摘要： The present invention relates to a system for the physical manipulation of free magnetic rotors in a circulatory system using a remotely placed magnetic field-generating stator. In one aspect, the invention relates to the control of magnetic particles in a fluid medium using permanent magnet-based or electromagnetic field-generating stator sources. Such a system can be useful for increasing the diffusion of therapeutic agents in a fluid medium, such as a human circulatory system, which can result in substantial clearance of fluid obstructions, such as vascular occlusions, in a circulatory system resulting in increased blood flow. Examples of vascular occlusions targeted by the system include, but are not limited to, atherosclerotic plaques, including fibrous caps, fatty buildup, coronary occlusions, arterial stenosis, restenosis, vein thrombi, arterial thrombi, cerebral thrombi, embolisms, hemorrhages, other blood clots, and very small vessels.

    摘要翻译： 本发明涉及一种用于使用远程放置的产生磁场的定子在循环系统中物理地操纵自由磁转子的系统。 一方面，本发明涉及使用基于永磁体或电磁场产生定子源的流体介质中的磁性颗粒的控制。 这种系统可用于增加治疗剂在诸如人类循环系统的流体培养基中的扩散，其可导致循环系统中的流体障碍（例如血管闭塞）的实质性清除，导致血流量增加。 系统靶向的血管闭塞的实例包括但不限于动脉粥样硬化斑块，包括纤维帽，脂肪积聚，冠状动脉闭塞，动脉狭窄，再狭窄，静脉血栓，动脉血栓，脑血栓，栓塞，出血，其他血块 ，和非常小的船只。