Thermo-induced stimuli-responsive membrane for leukocyte enrichment and application thereof

    公开(公告)号:US20240293784A1

    公开(公告)日:2024-09-05

    申请号:US18582695

    申请日:2024-02-21

    发明人: Yung Chang

    IPC分类号: B01D71/40 A61B5/15 B01D69/14

    摘要: A novel thermo-induced stimuli-responsive membrane for leukocyte enrichment and its application to white blood cells were disclosed. Specifically, the thermo-induced stimuli-responsive membrane for leukocyte enrichment comprises a layer coated on a porous substrate, and composition of the layer comprises at least one copolymer selected from one of group consisting of poly(acrylic acid-co-alkyl methacrylate), poly(N-alkyl acrylamide-co-alkyl methacrylate) and their mixture. In particular, the time for white blood cells recovery is within 1 hour, so as to obtain fresh and high purity white blood cells by using the novel thermo-induced stimuli-responsive membrane.