公开(公告)号：US08568608B2

公开(公告)日：2013-10-29

申请号：US11755950

申请日：2007-05-31

Applicant: Mark Brandon Shiflett ,  Akimichi Yokozeki

Inventor： Mark Brandon Shiflett ,  Akimichi Yokozeki

IPC: C09K5/04 ,  F25D11/00

CPC classification number: C09K5/041 ,  C10M171/008 ,  C10M2201/0803 ,  C10M2201/081 ,  C10M2201/084 ,  C10M2201/085 ,  C10M2201/0853 ,  C10M2201/087 ,  C10M2201/0873 ,  C10M2207/1213 ,  C10M2207/122 ,  C10M2215/02 ,  C10M2215/023 ,  C10M2215/22 ,  C10M2215/2203 ,  C10M2215/221 ,  C10M2215/224 ,  C10M2215/2245 ,  C10M2215/225 ,  C10M2219/0406 ,  C10M2219/044 ,  C10M2219/101 ,  C10M2219/104 ,  C10M2223/06 ,  C10M2223/0603 ,  C10M2223/063 ,  C10N2220/04 ,  C10N2240/30 ,  F25B31/002

Abstract: This invention relates to the use of ionic liquids as lubricants in vapor compression systems for cooling or heating. This invention also relates to an apparatus for adjusting temperature that operates a vapor compression cycle.

Abstract translation: 本发明涉及在用于冷却或加热的蒸汽压缩系统中使用离子液体作为润滑剂。 本发明还涉及一种用于调节运行蒸气压缩循环的温度的装置。

公开(公告)号：US07943556B2

公开(公告)日：2011-05-17

申请号：US11295711

申请日：2005-12-05

Applicant: Michael J. Mitrovich

Inventor： Michael J. Mitrovich

IPC: F16C33/18 ,  F16C33/04 ,  C10L1/16

CPC classification number: C10M111/04 ,  B82Y30/00 ,  C08K3/04 ,  C08K3/30 ,  C10M103/02 ,  C10M103/06 ,  C10M107/04 ,  C10M107/06 ,  C10M169/04 ,  C10M2201/041 ,  C10M2201/0413 ,  C10M2201/042 ,  C10M2201/0423 ,  C10M2201/0603 ,  C10M2201/0613 ,  C10M2201/062 ,  C10M2201/0623 ,  C10M2201/0653 ,  C10M2201/066 ,  C10M2201/0663 ,  C10M2201/0803 ,  C10M2201/0853 ,  C10M2201/0863 ,  C10M2201/0873 ,  C10M2201/1006 ,  C10M2201/102 ,  C10M2201/1023 ,  C10M2201/1033 ,  C10M2201/1053 ,  C10M2201/123 ,  C10M2205/022 ,  C10M2205/0225 ,  C10M2205/024 ,  C10M2205/0245 ,  C10M2205/14 ,  C10M2207/40 ,  C10M2209/1023 ,  C10M2209/123 ,  C10N2210/02 ,  C10N2230/06 ,  C10N2230/64 ,  C10N2240/00 ,  C10N2240/22 ,  C10N2240/30 ,  C10N2240/50 ,  C10N2240/52 ,  C10N2240/54 ,  C10N2240/56 ,  C10N2240/58 ,  C10N2240/60 ,  C10N2240/66 ,  C10N2250/08

Abstract: A solid lubricant and composition useful for lubricating the flanges of locomotive wheels, railcar wheels, rail tracks and in applications where it is desirable to reduce friction when metal contacts metal. The solid lubricant having from about 25% to about 70% by volume of a biopolymer polymeric carrier, about 5% to 75% percent by volume of organic and inorganic extreme pressure additives, about 0% to 20% by volume synthetic extreme pressure anti-wear liquid oil, and about 0% to 1% by volume optical brightener.

Abstract translation: 用于润滑机车车轮，轨道车轮，轨道轨道的凸缘的固体润滑剂和组合物，以及在金属接触金属时期望减少摩擦的应用中。 固体润滑剂具有约25体积％至约70体积％的生物聚合物聚合物载体，约5％至75体积％的有机和无机极压添加剂，约0体积％至20体积％ 磨损液体油，约0〜1％（体积）荧光增白剂。

公开(公告)号：US20110100081A1

公开(公告)日：2011-05-05

申请号：US12863805

申请日：2009-01-26

Applicant: Uwe Rau ,  Klaus-Dieter Nittel ,  Andreas Lang

Inventor： Uwe Rau ,  Klaus-Dieter Nittel ,  Andreas Lang

IPC: C10M105/34 ,  B05D1/36 ,  C25D9/04 ,  B21C9/02

CPC classification number: C10M173/02 ,  C10M111/04 ,  C10M2201/041 ,  C10M2201/062 ,  C10M2201/066 ,  C10M2201/0853 ,  C10M2201/102 ,  C10M2205/022 ,  C10M2205/024 ,  C10M2205/04 ,  C10M2205/16 ,  C10M2205/18 ,  C10M2209/084 ,  C10M2209/0845 ,  C10M2209/103 ,  C10M2215/042 ,  C10M2217/044 ,  C10M2217/045 ,  C10M2217/046 ,  C10M2227/02 ,  C10M2227/04 ,  C10M2229/02 ,  C10N2220/021 ,  C10N2230/06 ,  C10N2230/12 ,  C10N2240/402 ,  C10N2240/405 ,  C10N2240/407 ,  C10N2240/408 ,  C10N2240/409 ,  C10N2250/121 ,  C10N2250/141 ,  C10N2280/00

Abstract: The invention relates to a method for preparing metal workpieces for cold forming by first applying a phosphate layer and then applying a lubricant layer which has a major content in organic polymer material. The phosphate layer is formed by an aqueous acidic phosphating solution having a major content in calcium, magnesium or manganese and phosphate. The lubricant layer is formed by contacting the phosphated surface with an aqueous lubricant composition which has a content in organic polymer material based on ionomer and optionally also non-ionomer the organic polymer material used predominantly being monomers, oligomers, co-oligomers, polymers or copolymers based on ionomer, acrylic acid/methacrylic acid, epoxide, ethylene, polyamide, propylene, styrene, urethane, the ester or salt thereof. The invention also relates to the corresponding lubricant composition, to the lubricant layer produced thereof and to its use.

Abstract translation: 本发明涉及一种通过首先施加磷酸盐层制备用于冷成型的金属工件的方法，然后施加在有机聚合物材料中具有主要含量的润滑剂层。 磷酸盐层由主要含量为钙，镁或锰和磷酸盐的酸性磷酸水溶液形成。 润滑剂层是通过使磷酸盐化表面与含水润滑剂组合物形成的，所述水性润滑剂组合物基于离聚物和任选的非离聚物，其有机聚合物材料的含量主要用作单体，低聚物，共低聚物，聚合物或共聚物 基于离聚物，丙烯酸/甲基丙烯酸，环氧化物，乙烯，聚酰胺，丙烯，苯乙烯，氨基甲酸酯，其酯或盐。 本发明还涉及相应的润滑剂组合物，与其制备的润滑剂层及其用途。

公开(公告)号：US20090178454A1

公开(公告)日：2009-07-16

申请号：US12382215

申请日：2009-03-11

Applicant: Shinobu KOMIYAMA ,  Masayuki YOSHIDA ,  Hidehiro YAMAGUCHI

Inventor： Shinobu KOMIYAMA ,  Masayuki YOSHIDA ,  Hidehiro YAMAGUCHI

IPC: B21B45/02

CPC classification number: C10M169/04 ,  C10M173/02 ,  C10M2201/0623 ,  C10M2201/085 ,  C10M2201/0853 ,  C10M2207/12 ,  C10M2207/1203 ,  C10M2207/1253 ,  C10M2207/126 ,  C10N2210/02 ,  C10N2220/084 ,  C10N2230/06 ,  C10N2240/402 ,  C10N2240/405 ,  C10N2250/08 ,  C10M2207/125

Abstract: Particles each of which consists of an inorganic polyvalent metal compound as a nucleus and a coating of a metallic soap of the polyvalent metal coating the nucleus (coated particles); products and preparation processes using the particles; a lubricating coating forming agent wherein particles each of which consists of a polyvalent metal salt of phosphoric acid as a nucleus and a coating of a metallic soap of the polyvalent metal coating the surface of the nucleus are suspended in an aqueous solution of a water soluble inorganic salt and/or a water soluble organic acid salt; and a lubricating coating. The coated particles are novel particles which can be used as an ingredient of coating-type lubricating coating; are excellent in seizure resistance; can inhibit wear of tools at the time of plastic working since the friction coefficient of the surface of the particles is low; and are slow to cause pollution of working oils. Lubricating coating obtained by applying the lubricating coating forming agent onto the surface of a metallic material gives excellent cold plastic working properties, namely lubricity and seizure resistance to the metallic material.

Abstract translation: 各自由作为核的无机多价金属化合物和包覆核（涂覆颗粒）的多价金属的金属皂的涂层组成的颗粒; 使用颗粒的产品和制备过程; 润滑涂层形成剂，其中由磷酸的多价金属盐作为核的颗粒和涂覆在核表面上的多价金属的金属皂的涂层悬浮在水溶性无机的水溶液中 盐和/或水溶性有机酸盐; 和润滑涂层。 涂层颗粒是可用作涂层型润滑涂层成分的新型颗粒; 抗癫痫发作优良; 由于颗粒表面的摩擦系数低，因此可以抑制塑料加工时工具的磨损; 造成工作油污染缓慢。 通过将润滑涂层形成剂涂覆在金属材料的表面上获得的润滑涂层具有优异的冷塑性加工性能，即对金属材料的润滑性和抗咬合性。

公开(公告)号：US20090053268A1

公开(公告)日：2009-02-26

申请号：US11843303

申请日：2007-08-22

Applicant: Juan J. DePablo ,  Mary Jo Biddy

Inventor： Juan J. DePablo ,  Mary Jo Biddy

IPC: C11C5/00 ,  A61K9/10 ,  A61K47/44 ,  C10M169/04 ,  C08L91/06 ,  C09G1/08 ,  A61K8/92 ,  A61K8/04

CPC classification number: C08L91/06 ,  A61K8/0241 ,  A61K8/92 ,  A61K2800/413 ,  A61K2800/651 ,  A61Q19/00 ,  B82Y5/00 ,  B82Y30/00 ,  C10M171/06 ,  C10M2201/061 ,  C10M2201/0613 ,  C10M2201/062 ,  C10M2201/0623 ,  C10M2201/08 ,  C10M2201/0803 ,  C10M2201/084 ,  C10M2201/085 ,  C10M2201/0853 ,  C10M2205/183 ,  C10M2207/10 ,  C10M2207/103 ,  C10M2207/401 ,  C10N2210/01 ,  C10N2210/02 ,  C11C5/002

Abstract: The present invention provides compositions and products, such as waxes and lubricants, comprising a plurality of nanoparticles dispersed in a continuous phase comprising a vegetable oil derived material, such as one or more vegetable oils or a synthetic product derived from one or more vegetable oils. Incorporation of nanoparticles in the present compositions is beneficial for providing mechanical, thermal and/or chemical properties useful for a selected product or product application. In some compositions of the present invention, for example, incorporation of the nanoparticle component provides compositions derived from one or more vegetable oils exhibiting enhanced mechanical stability, hardness, viscosity, thermal stability and mechanical strength.

Abstract translation: 本发明提供组合物和产品，例如蜡和润滑剂，其包含分散在连续相中的多种纳米颗粒，所述连续相包含植物油衍生物质，例如一种或多种植物油或衍生自一种或多种植物油的合成产品。 在本发明组合物中纳入纳米颗粒有利于提供对所选产品或产品应用有用的机械，热和/或化学性质。 在本发明的一些组合物中，例如，纳米颗粒组分的掺入提供衍生自一种或多种植物油的组合物，其表现出增强的机械稳定性，硬度，粘度，热稳定性和机械强度。

公开(公告)号：US07358216B2

公开(公告)日：2008-04-15

申请号：US10733419

申请日：2003-12-11

Applicant: Richard Levy

Inventor： Richard Levy

IPC: C10M125/00 ,  C10M145/14

CPC classification number: C10M111/04 ,  C10M101/02 ,  C10M101/025 ,  C10M103/00 ,  C10M103/02 ,  C10M103/04 ,  C10M103/06 ,  C10M105/04 ,  C10M105/06 ,  C10M105/18 ,  C10M105/36 ,  C10M105/80 ,  C10M107/00 ,  C10M107/02 ,  C10M107/28 ,  C10M107/34 ,  C10M107/36 ,  C10M107/38 ,  C10M107/42 ,  C10M107/44 ,  C10M125/02 ,  C10M125/04 ,  C10M125/10 ,  C10M125/22 ,  C10M125/24 ,  C10M125/26 ,  C10M145/12 ,  C10M145/14 ,  C10M145/40 ,  C10M149/06 ,  C10M149/08 ,  C10M149/12 ,  C10M173/02 ,  C10M2201/0413 ,  C10M2201/053 ,  C10M2201/0623 ,  C10M2201/0653 ,  C10M2201/0663 ,  C10M2201/0853 ,  C10M2201/0873 ,  C10M2201/1023 ,  C10M2201/1033 ,  C10M2203/1006 ,  C10M2207/2825 ,  C10M2209/0845 ,  C10M2209/1045 ,  C10M2209/123 ,  C10M2217/0245 ,  C10M2217/0265 ,  C10N2230/06 ,  C10N2250/08 ,  C10N2250/10 ,  C10N2250/12 ,  C10N2250/16 ,  C10N2250/18 ,  Y10T428/2927 ,  Y10T428/2933 ,  Y10T428/294 ,  Y10T428/2962 ,  C10M2209/1085

Abstract: A process is disclosed for manufacturing a lubricant composition comprising combining a superabsorbent polymer with a material for decreasing friction between moving surfaces. The superabsorbent polymer absorbs from about 25 to greater than 100 times its weight in water and may comprise a polymer of acrylic acid, an acrylic ester, acrylonitrile or acrylamide, including co-polymers thereof or starch graft co-polymers thereof or mixtures thereof. A product produced by the process includes the material for decreasing friction comprising a petroleum lubricant containing an additive, water containing an additive, synthetic lubricant, grease, solid lubricant or metal working lubricant, wherein the synthetic lubricant, grease, solid lubricant or metal working lubricant optionally contain an additive. A process comprising controlling the delivery of a lubricant to at least one of two moving surfaces in order to decrease friction between said moving surfaces, is also disclosed. This process includes applying the lubricant composition to at least one of the surfaces. The lubricant composition in this instance comprises a superabsorbent polymer combined with a material for decreasing friction between moving surfaces, wherein the material for decreasing friction comprises a petroleum lubricant, water, synthetic lubricant, grease, solid lubricant or metal working lubricant, and optionally an additive.

公开(公告)号：US20040167043A1

公开(公告)日：2004-08-26

申请号：US10763687

申请日：2004-01-24

Applicant: Lee County Mosquito Control District

Inventor： Richard Levy

IPC: C10M101/00

CPC classification number: C10M111/04 ,  C10M2201/0413 ,  C10M2201/053 ,  C10M2201/0623 ,  C10M2201/0653 ,  C10M2201/0663 ,  C10M2201/0853 ,  C10M2201/0873 ,  C10M2201/1023 ,  C10M2201/1033 ,  C10M2203/1006 ,  C10M2207/2825 ,  C10M2209/0845 ,  C10M2209/1045 ,  C10M2209/123 ,  C10M2217/0245 ,  C10M2217/0265 ,  C10N2230/06 ,  C10N2250/08 ,  C10N2250/10 ,  C10N2250/12 ,  C10N2250/16 ,  C10N2250/18 ,  F16C33/109 ,  F16C2202/52 ,  C10M2209/1085

Abstract: A process is disclosed for manufacturing a lubricant composition comprising combining a superabsorbent polymer with a material for decreasing friction between moving surfaces. The superabsorbent polymer absorbs from about 25 to greater than 100 times its weight in water and may comprise a polymer of acrylic acid, an acrylic ester, acrylonitrile or acrylamide, including co-polymers thereof or starch graft co-polymers thereof or mixtures thereof. A product produced by the process includes the material for decreasing friction comprising a petroleum lubricant containing an additive, water containing an additive, synthetic lubricant, grease, solid lubricant or metal working lubricant, wherein the synthetic lubricant, grease, solid lubricant or metal working lubricant optionally contain an additive. A process comprising controlling the delivery of a lubricant to at least one of two moving surfaces in order to decrease friction between said moving surfaces, is also disclosed. This process includes applying the lubricant composition to at least one of the surfaces. The lubricant composition in this instance comprises a superabsorbent polymer combined with a material for decreasing friction between moving surfaces, wherein the material for decreasing friction comprises a petroleum lubricant, water, synthetic lubricant, grease, solid lubricant or metal working lubricant, and optionally an additive.

Abstract translation: 公开了一种用于制造润滑剂组合物的方法，其包括将超吸收聚合物与用于减少运动表面之间摩擦的材料组合。 超吸收性聚合物在水中吸收其重量的约25至大于100倍，并且可以包含丙烯酸，丙烯酸酯，丙烯腈或丙烯酰胺的聚合物，包括其共聚物或其淀粉接枝共聚物或其混合物。 通过该方法生产的产品包括用于减少摩擦的材料，其包含含有添加剂的石油润滑剂，含有添加剂的水，合成润滑剂，润滑脂，固体润滑剂或金属加工润滑剂，其中合成润滑剂，润滑脂，固体润滑剂或金属加工润滑剂 任选地含有添加剂。 还公开了一种方法，其包括控制将润滑剂输送到两个移动表面中的至少一个以减少所述移动表面之间的摩擦。 该方法包括将润滑剂组合物施加到至少一个表面。 在这种情况下，润滑剂组合物包括与用于减少运动表面之间的摩擦的材料组合的超吸收性聚合物，其中用于减少摩擦的材料包括石油润滑剂，水，合成润滑剂，润滑脂，固体润滑剂或金属加工润滑剂，以及任选的添加剂 。

公开(公告)号：US20040138072A1

公开(公告)日：2004-07-15

申请号：US10733419

申请日：2003-12-11

Applicant: Lee County Mosquito Control District

Inventor： Richard Levy

IPC: C10M141/00 ,  C10M173/00

CPC classification number: C10M111/04 ,  C10M101/02 ,  C10M101/025 ,  C10M103/00 ,  C10M103/02 ,  C10M103/04 ,  C10M103/06 ,  C10M105/04 ,  C10M105/06 ,  C10M105/18 ,  C10M105/36 ,  C10M105/80 ,  C10M107/00 ,  C10M107/02 ,  C10M107/28 ,  C10M107/34 ,  C10M107/36 ,  C10M107/38 ,  C10M107/42 ,  C10M107/44 ,  C10M125/02 ,  C10M125/04 ,  C10M125/10 ,  C10M125/22 ,  C10M125/24 ,  C10M125/26 ,  C10M145/12 ,  C10M145/14 ,  C10M145/40 ,  C10M149/06 ,  C10M149/08 ,  C10M149/12 ,  C10M173/02 ,  C10M2201/0413 ,  C10M2201/053 ,  C10M2201/0623 ,  C10M2201/0653 ,  C10M2201/0663 ,  C10M2201/0853 ,  C10M2201/0873 ,  C10M2201/1023 ,  C10M2201/1033 ,  C10M2203/1006 ,  C10M2207/2825 ,  C10M2209/0845 ,  C10M2209/1045 ,  C10M2209/123 ,  C10M2217/0245 ,  C10M2217/0265 ,  C10N2230/06 ,  C10N2250/08 ,  C10N2250/10 ,  C10N2250/12 ,  C10N2250/16 ,  C10N2250/18 ,  Y10T428/2927 ,  Y10T428/2933 ,  Y10T428/294 ,  Y10T428/2962 ,  C10M2209/1085

Abstract: A process is disclosed for manufacturing a lubricant composition comprising combining a superabsorbent polymer with a material for decreasing friction between moving surfaces. The superabsorbent polymer absorbs from about 25 to greater than 100 times its weight in water and may comprise a polymer of acrylic acid, an acrylic ester, acrylonitrile or acrylamide, including co-polymers thereof or starch graft co-polymers thereof or mixtures thereof. A product produced by the process includes the material for decreasing friction comprising a petroleum lubricant containing an additive, water containing an additive, synthetic lubricant, grease, solid lubricant or metal working lubricant, wherein the synthetic lubricant, grease, solid lubricant or metal working lubricant optionally contain an additive. A process comprising controlling the delivery of a lubricant to at least one of two moving surfaces in order to decrease friction between said moving surfaces, is also disclosed. This process includes applying the lubricant composition to at least one of the surfaces. The lubricant composition in this instance comprises a superabsorbent polymer combined with a material for decreasing friction between moving surfaces, wherein the material for decreasing friction comprises a petroleum lubricant, water, synthetic lubricant, grease, solid lubricant or metal working lubricant, and optionally an additive.

Abstract translation: 公开了一种用于制造润滑剂组合物的方法，其包括将超吸收聚合物与用于减少运动表面之间摩擦的材料组合。 超吸收性聚合物在水中吸收其重量的约25至大于100倍，并且可以包含丙烯酸，丙烯酸酯，丙烯腈或丙烯酰胺的聚合物，包括其共聚物或其淀粉接枝共聚物或其混合物。 通过该方法生产的产品包括用于减少摩擦的材料，其包含含有添加剂的石油润滑剂，含有添加剂的水，合成润滑剂，润滑脂，固体润滑剂或金属加工润滑剂，其中合成润滑剂，润滑脂，固体润滑剂或金属加工润滑剂 任选地含有添加剂。 还公开了一种方法，其包括控制将润滑剂输送到两个移动表面中的至少一个以减少所述移动表面之间的摩擦。 该方法包括将润滑剂组合物施加到至少一个表面。 在这种情况下，润滑剂组合物包括与用于减少运动表面之间的摩擦的材料组合的超吸收性聚合物，其中用于减少摩擦的材料包括石油润滑剂，水，合成润滑剂，润滑脂，固体润滑剂或金属加工润滑剂，以及任选的添加剂 。

公开(公告)号：US20040029748A1

公开(公告)日：2004-02-12

申请号：US10614114

申请日：2003-07-07

Applicant: LEE COUNTY MOSQUITO CONTROL DISTRICT

Inventor： Richard Levy

IPC: C10M145/14 ,  C10M149/04

CPC classification number: C10M111/04 ,  C10M101/02 ,  C10M101/025 ,  C10M103/00 ,  C10M103/02 ,  C10M103/04 ,  C10M103/06 ,  C10M105/04 ,  C10M105/06 ,  C10M105/18 ,  C10M105/36 ,  C10M105/80 ,  C10M107/00 ,  C10M107/02 ,  C10M107/28 ,  C10M107/34 ,  C10M107/36 ,  C10M107/38 ,  C10M107/42 ,  C10M107/44 ,  C10M125/02 ,  C10M125/04 ,  C10M125/10 ,  C10M125/22 ,  C10M125/24 ,  C10M125/26 ,  C10M145/12 ,  C10M145/14 ,  C10M145/40 ,  C10M149/06 ,  C10M149/08 ,  C10M149/12 ,  C10M173/02 ,  C10M2201/0413 ,  C10M2201/053 ,  C10M2201/0623 ,  C10M2201/0653 ,  C10M2201/0663 ,  C10M2201/0853 ,  C10M2201/0873 ,  C10M2201/1023 ,  C10M2201/1033 ,  C10M2203/1006 ,  C10M2207/2825 ,  C10M2209/0845 ,  C10M2209/1045 ,  C10M2209/123 ,  C10M2217/0245 ,  C10M2217/0265 ,  C10N2230/06 ,  C10N2250/08 ,  C10N2250/10 ,  C10N2250/12 ,  C10N2250/16 ,  C10N2250/18 ,  Y10T428/2927 ,  Y10T428/2933 ,  Y10T428/294 ,  Y10T428/2962 ,  C10M2209/1085

Abstract: A process is disclosed for manufacturing a lubricant composition comprising combining a superabsorbent polymer with a material for decreasing friction between moving surfaces. The superabsorbent polymer absorbs from about 25 to greater than 100 times its weight in water and may comprise a polymer of acrylic acid, an acrylic ester, acrylonitrile or acrylamide, including co-polymers thereof or starch graft co-polymers thereof or mixtures thereof. A product produced by the process includes the material for decreasing friction comprising a petroleum lubricant containing an additive, water containing an additive, synthetic lubricant, grease, solid lubricant or metal working lubricant, wherein the synthetic lubricant, grease, solid lubricant or metal working lubricant optionally contain an additive. A process comprising controlling the delivery of a lubricant to at least one of two moving surfaces in order to decrease friction between said moving surfaces, is also disclosed. This process includes applying the lubricant composition to at least one of the surfaces. The lubricant composition in this instance comprises a superabsorbent polymer combined with a material for decreasing friction between moving surfaces, wherein the material for decreasing friction comprises a petroleum lubricant, water, synthetic lubricant, grease, solid lubricant or metal working lubricant, and optionally an additive.

公开(公告)号：US20030203903A1

公开(公告)日：2003-10-30

申请号：US10243141

申请日：2002-09-14

Inventor： Lynn M. Rose ,  David J. Porubek ,  Alan B. Montgomery

IPC: A61K031/538 ,  A61K031/7036

CPC classification number: A61K31/538 ,  A61K31/00 ,  A61K31/70 ,  C10M101/025 ,  C10M103/06 ,  C10M105/14 ,  C10M105/24 ,  C10M107/34 ,  C10M107/36 ,  C10M111/00 ,  C10M2201/0603 ,  C10M2201/0613 ,  C10M2201/0623 ,  C10M2201/0653 ,  C10M2201/0663 ,  C10M2201/0803 ,  C10M2201/0853 ,  C10M2201/0863 ,  C10M2201/0873 ,  C10M2201/1006 ,  C10M2201/1023 ,  C10M2201/1033 ,  C10M2201/1053 ,  C10M2201/123 ,  C10M2205/143 ,  C10M2205/163 ,  C10M2205/173 ,  C10M2205/183 ,  C10M2207/0225 ,  C10M2207/1203 ,  C10M2207/1213 ,  C10M2207/1253 ,  C10M2207/163 ,  C10M2207/183 ,  C10M2207/203 ,  C10M2207/243 ,  C10M2209/1033 ,  C10M2209/1045 ,  C10M2209/1055 ,  C10M2209/1065 ,  C10M2209/1075 ,  C10M2209/1085 ,  C10M2209/1095 ,  C10M2209/123 ,  Y10S514/924 ,  Y10S514/931 ,  A61K2300/00

Abstract: A method for treatment of bacterial infections with rifalazil administered once-weekly, or twice-weekly. A method for treatment of tuberculosis caused by Mycobacterium tuberculosis, infections caused by Mycobacterium avium complex, infections caused by Chlamydia pneumoniae and infections caused by Helicobacter pylori by administering to a patient suffering from the bacterial infection 1-100 mg of rifalazil once or twice a week. In this dose regimen, the treatment is fast, efficacious and eliminates undesirable secondary symptoms observed with daily doses of 1-50 mg of rifalazil.

Abstract translation: 一种每周一次或每周两次给予利福拉齐治疗细菌感染的方法。 一种治疗由结核分枝杆菌引起的结核病，由分枝杆菌复合体引起的感染，肺炎衣原体引起的感染和幽门螺杆菌感染引起的感染的方法，通过对患有细菌感染的患者施用1-100mg的利福拉齐，每周一次或两次 。 在这种剂量方案中，治疗是快速，有效的，并且消除了每日剂量的1-50mg利福肼的不期望的继发症状。